Click here to switch to the map view.

The map label for this gene is moaA [H]

Identifier: 21227117

GI number: 21227117

Start: 1188086

End: 1189219

Strand: Direct

Name: moaA [H]

Synonym: MM_1015

Alternate gene names: 21227117

Gene position: 1188086-1189219 (Clockwise)

Preceding gene: 21227116

Following gene: 21227118

Centisome position: 29.0

GC content: 43.3

Gene sequence:

>1134_bases
TTGATCGAAAAGGATGAAGATGGAATCTACATAGGAACTGTTCCCGAACTGAAAGGGTGCTATAGCTATGGAGATATTAA
TGACCCCCTTTTCCATTTTTACCCGAATTTCTTTTTAGAAAAACAAAACGCGATTGTTATGTCCCGATTTGATCCCATCC
TTGCTTCAAGAGCACTCTGGCAAATAAGAATCAAAAAACGCCCTTTTGTCCTCTCTCACGGCGTAAATGCTAATTGTAAT
ATGCGCTGCAAGTTCTGTGAATACTGGAGGAAAGAACCCGGAAAAGAACCGTCCAGAGACGAGGTCTTCAGGCTGCTCAA
TGATGCAAAAAAATTTGGAATCGGAGTTTACAATGCCTGGACCACGGAACCTCTCCTCAGAAAGGACCTGCCCCTCATAA
TGGCTCGCGCAAAGGAACTCGGGATGGTTACTTCCATGGTCACGAACGGGAAGCTTCTTTACGAAAGAGTGGAAGAGCTT
GAGAATGTGGACTACCTTTCGGTTTCAGTAGACGGGACAGAAAGCTATAAAGAAATCAGGAAAATGGATTTCGGAACCCT
TCTGAAAGGCTTGAAAAAAGCTATTGAGGTAAGAAAACTCCAGAAGCAGAAAAACCCGATCCTGATGAACTGCGTGCTCA
CAGGAAAGAACCTTGATGATATTGAAACCCTTATTTTGCTTGCAGAAAAACTGGGTGTGAAAATTTCTTTTGAACCAGTA
CATGAGTTCCCCGGAATCAGCCGGGAAATATGGGAAGAAATAGGAATCAGGGATAAGGAAAAGTTCCGCAGCACCGTTAA
CCTCATAATCGAGATGAAAGAAAAGGGCTACCCCATAATCAATTCCAAGACCTACCTGGGGATGGTCAGGGACGAAAAAA
AGGATTACAAATGCAGAGCAAGTGGCATTATTATTAACGTTACGCATGACGGAACTGCCGAGACCTGCCGTGTGCATCAG
GAACCTCTTGGAAACGTTATGAAAGACGGTTTTGAAAAGGTATGGAAGAACTCTGCGCAGCGCAGGGAAGAGATCGTAGA
AAACTGTAAAGGCTGCCTCTTTTTTGGATATACGGAAAACAGTTTAATGCAGAGTTTCAATCCTGAAGTTTTAATGCATT
ACGAATGGATGTGA

Upstream 100 bases:

>100_bases
TCCACAGATTCCCTACACATCTTCAAAATCATATTTACCTATTTATAGAATAAGATAGAGAGTATGAAGCAGTCAATACG
ACAAGCAAAAATTTGTCGTG

Downstream 100 bases:

>100_bases
TGCCCGAGTTCCGCTTCGGCACCCGAGTTCCGCTTCGGCACCCGAGTTCCGCTTCGGCACCCGAGTTCCGCTTCGGGAGC
ACGGTGTCCTTTTCGGTCGC

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MIEKDEDGIYIGTVPELKGCYSYGDINDPLFHFYPNFFLEKQNAIVMSRFDPILASRALWQIRIKKRPFVLSHGVNANCN
MRCKFCEYWRKEPGKEPSRDEVFRLLNDAKKFGIGVYNAWTTEPLLRKDLPLIMARAKELGMVTSMVTNGKLLYERVEEL
ENVDYLSVSVDGTESYKEIRKMDFGTLLKGLKKAIEVRKLQKQKNPILMNCVLTGKNLDDIETLILLAEKLGVKISFEPV
HEFPGISREIWEEIGIRDKEKFRSTVNLIIEMKEKGYPIINSKTYLGMVRDEKKDYKCRASGIIINVTHDGTAETCRVHQ
EPLGNVMKDGFEKVWKNSAQRREEIVENCKGCLFFGYTENSLMQSFNPEVLMHYEWM

Sequences:

>Translated_377_residues
MIEKDEDGIYIGTVPELKGCYSYGDINDPLFHFYPNFFLEKQNAIVMSRFDPILASRALWQIRIKKRPFVLSHGVNANCN
MRCKFCEYWRKEPGKEPSRDEVFRLLNDAKKFGIGVYNAWTTEPLLRKDLPLIMARAKELGMVTSMVTNGKLLYERVEEL
ENVDYLSVSVDGTESYKEIRKMDFGTLLKGLKKAIEVRKLQKQKNPILMNCVLTGKNLDDIETLILLAEKLGVKISFEPV
HEFPGISREIWEEIGIRDKEKFRSTVNLIIEMKEKGYPIINSKTYLGMVRDEKKDYKCRASGIIINVTHDGTAETCRVHQ
EPLGNVMKDGFEKVWKNSAQRREEIVENCKGCLFFGYTENSLMQSFNPEVLMHYEWM
>Mature_377_residues
MIEKDEDGIYIGTVPELKGCYSYGDINDPLFHFYPNFFLEKQNAIVMSRFDPILASRALWQIRIKKRPFVLSHGVNANCN
MRCKFCEYWRKEPGKEPSRDEVFRLLNDAKKFGIGVYNAWTTEPLLRKDLPLIMARAKELGMVTSMVTNGKLLYERVEEL
ENVDYLSVSVDGTESYKEIRKMDFGTLLKGLKKAIEVRKLQKQKNPILMNCVLTGKNLDDIETLILLAEKLGVKISFEPV
HEFPGISREIWEEIGIRDKEKFRSTVNLIIEMKEKGYPIINSKTYLGMVRDEKKDYKCRASGIIINVTHDGTAETCRVHQ
EPLGNVMKDGFEKVWKNSAQRREEIVENCKGCLFFGYTENSLMQSFNPEVLMHYEWM

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013485
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 43745; Mature: 43745

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKDEDGIYIGTVPELKGCYSYGDINDPLFHFYPNFFLEKQNAIVMSRFDPILASRALW
CCCCCCCCEEEECCHHHHCCCCCCCCCCCHHHHCCCCEEECCCEEEEECCCHHHHHHHHE
QIRIKKRPFVLSHGVNANCNMRCKFCEYWRKEPGKEPSRDEVFRLLNDAKKFGIGVYNAW
EEEECCCCEEEECCCCCCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECC
TTEPLLRKDLPLIMARAKELGMVTSMVTNGKLLYERVEELENVDYLSVSVDGTESYKEIR
CCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
KMDFGTLLKGLKKAIEVRKLQKQKNPILMNCVLTGKNLDDIETLILLAEKLGVKISFEPV
HCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCH
HEFPGISREIWEEIGIRDKEKFRSTVNLIIEMKEKGYPIINSKTYLGMVRDEKKDYKCRA
HHCCCCCHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCEECCCEEEEEECCCCCCCEEEE
SGIIINVTHDGTAETCRVHQEPLGNVMKDGFEKVWKNSAQRREEIVENCKGCLFFGYTEN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHH
SLMQSFNPEVLMHYEWM
HHHHHCCCCEEEEEECC
>Mature Secondary Structure
MIEKDEDGIYIGTVPELKGCYSYGDINDPLFHFYPNFFLEKQNAIVMSRFDPILASRALW
CCCCCCCCEEEECCHHHHCCCCCCCCCCCHHHHCCCCEEECCCEEEEECCCHHHHHHHHE
QIRIKKRPFVLSHGVNANCNMRCKFCEYWRKEPGKEPSRDEVFRLLNDAKKFGIGVYNAW
EEEECCCCEEEECCCCCCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECC
TTEPLLRKDLPLIMARAKELGMVTSMVTNGKLLYERVEELENVDYLSVSVDGTESYKEIR
CCCHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHH
KMDFGTLLKGLKKAIEVRKLQKQKNPILMNCVLTGKNLDDIETLILLAEKLGVKISFEPV
HCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHCCEEEECCH
HEFPGISREIWEEIGIRDKEKFRSTVNLIIEMKEKGYPIINSKTYLGMVRDEKKDYKCRA
HHCCCCCHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCEECCCEEEEEECCCCCCCEEEE
SGIIINVTHDGTAETCRVHQEPLGNVMKDGFEKVWKNSAQRREEIVENCKGCLFFGYTEN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHH
SLMQSFNPEVLMHYEWM
HHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]