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The map label for this gene is ftsZ [H]

Identifier: 21227110

GI number: 21227110

Start: 1182688

End: 1183812

Strand: Direct

Name: ftsZ [H]

Synonym: MM_1008

Alternate gene names: 21227110

Gene position: 1182688-1183812 (Clockwise)

Preceding gene: 21227109

Following gene: 21227111

Centisome position: 28.87

GC content: 49.24

Gene sequence:

>1125_bases
ATGAGATCCATTGTGGAAGAAGCCCTTGCTCGATCTGCCCTGGAAGGACGTGGTGGGCAGGGAAATAACTCAAATTCGGA
TTACTCTGATGAAAACATAGAAGTGGACGCTGAACTTGAAGAAATACTGAGAAGCCTCAAAACAACTATCAAAGTGGTAG
GTTGCGGAGGCGGCGGTTCAAACAGTATACAGAGAATGATGGGCGAAGGTATCCAGGGAGCAGACCTTGTTGCCATAAAC
ACTGACGCTCAGCACCTTCTTCATATACGCTCCGGCAAAAAGATTCTCATCGGGAAAAAGAAAACCCGAGGGCTTGGAGC
CGGCAGTCTCCCCCAGATCGGAGAAGATGCAGCAATCGAGAGTATTGATGAGATTAACAAGATCGTCCAGGGCTCGGATA
TGGTTTTTATCACCGCGGGTCTTGGAGGAGGAACAGGGACAGGATCTGCACCAATAGTTGCTGAGGCAGCCAGAGATTCA
GGCGCCCTTACTATTGCAGTTGTGACTCTTCCGTTTAGCGTGGAAGGGCATGTCAGGAGGACAAATGCCGAAGCAGGCCT
CGAGCGCCTGAGAGACGTAGCCGATACGGTAATAGTTGTCCCAAACGATAAGCTGATTGAAGTAGTCCCGAAGCTTCCTC
TGCAGGCTGCCTTTAAGGTCTCTGACGAAGTCCTTATGAGAGCTGTAAAAGGTATAACCGAACTTATCACAAAGCCCGGG
CTTGTTAACCTTGACTTTGCAGATATAAGGACTGTAATGCAGAACGGAGGCGTTGCTATGATAGGACTTGGAGAATCTGA
CGGTGAAAACAAAGCTGTCGAATCAGTCCAGAAAGCACTGCGCAGCCCGCTCCTTGATGTGGACATATCCGGTGCAACCT
CTGCCCTCGTTAACGTGGTTGGAGGTCCTGACATGACCATTTCTGAAGCAGAATCTGTGGTACAGGAAGTCTACAGCCGC
ATAGACAGCAATGCTCGCCTTATCTGGGGTGCCCAGGTTGATCCGGATCTCGAAAAGACAGTACGTACAATGATAGTGGT
TACAGGAGTTACCTCCGCTCAGATATATGGGCACGGAAACGATAAGGACATCACATATAAGTACGGAATTGACTTCGTAG
AGTGA

Upstream 100 bases:

>100_bases
ATATGTGATGGTTAAAATAATTTTTTCCGTGTTGTAACATACTTATAGTTAATACAATTCATCAAATGATCACCCCAGCA
GAATGGAGGAAAACAGTAGC

Downstream 100 bases:

>100_bases
TCAGAGAGATGAAAAAGTAAAAATGGATAAAAACGTTCGGTTGGAGAAAAATACTGTTTTCCTCCTCTTAAGCTAAAAAG
AAGGAACGTAGAAATATAAA

Product: cell division protein FtsZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRSIVEEALARSALEGRGGQGNNSNSDYSDENIEVDAELEEILRSLKTTIKVVGCGGGGSNSIQRMMGEGIQGADLVAIN
TDAQHLLHIRSGKKILIGKKKTRGLGAGSLPQIGEDAAIESIDEINKIVQGSDMVFITAGLGGGTGTGSAPIVAEAARDS
GALTIAVVTLPFSVEGHVRRTNAEAGLERLRDVADTVIVVPNDKLIEVVPKLPLQAAFKVSDEVLMRAVKGITELITKPG
LVNLDFADIRTVMQNGGVAMIGLGESDGENKAVESVQKALRSPLLDVDISGATSALVNVVGGPDMTISEAESVVQEVYSR
IDSNARLIWGAQVDPDLEKTVRTMIVVTGVTSAQIYGHGNDKDITYKYGIDFVE

Sequences:

>Translated_374_residues
MRSIVEEALARSALEGRGGQGNNSNSDYSDENIEVDAELEEILRSLKTTIKVVGCGGGGSNSIQRMMGEGIQGADLVAIN
TDAQHLLHIRSGKKILIGKKKTRGLGAGSLPQIGEDAAIESIDEINKIVQGSDMVFITAGLGGGTGTGSAPIVAEAARDS
GALTIAVVTLPFSVEGHVRRTNAEAGLERLRDVADTVIVVPNDKLIEVVPKLPLQAAFKVSDEVLMRAVKGITELITKPG
LVNLDFADIRTVMQNGGVAMIGLGESDGENKAVESVQKALRSPLLDVDISGATSALVNVVGGPDMTISEAESVVQEVYSR
IDSNARLIWGAQVDPDLEKTVRTMIVVTGVTSAQIYGHGNDKDITYKYGIDFVE
>Mature_374_residues
MRSIVEEALARSALEGRGGQGNNSNSDYSDENIEVDAELEEILRSLKTTIKVVGCGGGGSNSIQRMMGEGIQGADLVAIN
TDAQHLLHIRSGKKILIGKKKTRGLGAGSLPQIGEDAAIESIDEINKIVQGSDMVFITAGLGGGTGTGSAPIVAEAARDS
GALTIAVVTLPFSVEGHVRRTNAEAGLERLRDVADTVIVVPNDKLIEVVPKLPLQAAFKVSDEVLMRAVKGITELITKPG
LVNLDFADIRTVMQNGGVAMIGLGESDGENKAVESVQKALRSPLLDVDISGATSALVNVVGGPDMTISEAESVVQEVYSR
IDSNARLIWGAQVDPDLEKTVRTMIVVTGVTSAQIYGHGNDKDITYKYGIDFVE

Specific function: This protein is essential to the cell-division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. B

COG id: COG0206

COG function: function code D; Cell division GTPase

Gene ontology:

Cell location: Cytoplasm. Assemble at the Inner Surface of the Cytoplasmic Membrane. [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsZ family [H]

Homologues:

Organism=Escherichia coli, GI1786284, Length=292, Percent_Identity=46.5753424657534, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: 320 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020805
- InterPro:   IPR000158
- InterPro:   IPR008280
- InterPro:   IPR018316
- InterPro:   IPR003008 [H]

Pfam domain/function: PF00091 Tubulin [H]

EC number: NA

Molecular weight: Translated: 39359; Mature: 39359

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01134 FTSZ_1 ; PS01135 FTSZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIVEEALARSALEGRGGQGNNSNSDYSDENIEVDAELEEILRSLKTTIKVVGCGGGGS
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHEEEEEECCCCCH
NSIQRMMGEGIQGADLVAINTDAQHLLHIRSGKKILIGKKKTRGLGAGSLPQIGEDAAIE
HHHHHHHCCCCCCCEEEEEECCHHHHEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHH
SIDEINKIVQGSDMVFITAGLGGGTGTGSAPIVAEAARDSGALTIAVVTLPFSVEGHVRR
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEEEEEECCCCEEE
TNAEAGLERLRDVADTVIVVPNDKLIEVVPKLPLQAAFKVSDEVLMRAVKGITELITKPG
CCHHHHHHHHHHHHCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LVNLDFADIRTVMQNGGVAMIGLGESDGENKAVESVQKALRSPLLDVDISGATSALVNVV
EEECCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHC
GGPDMTISEAESVVQEVYSRIDSNARLIWGAQVDPDLEKTVRTMIVVTGVTSAQIYGHGN
CCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHEEEEECCCEEEEEECCC
DKDITYKYGIDFVE
CCCEEEEECCCCCC
>Mature Secondary Structure
MRSIVEEALARSALEGRGGQGNNSNSDYSDENIEVDAELEEILRSLKTTIKVVGCGGGGS
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHEEEEEECCCCCH
NSIQRMMGEGIQGADLVAINTDAQHLLHIRSGKKILIGKKKTRGLGAGSLPQIGEDAAIE
HHHHHHHCCCCCCCEEEEEECCHHHHEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHH
SIDEINKIVQGSDMVFITAGLGGGTGTGSAPIVAEAARDSGALTIAVVTLPFSVEGHVRR
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEEEEEECCCCEEE
TNAEAGLERLRDVADTVIVVPNDKLIEVVPKLPLQAAFKVSDEVLMRAVKGITELITKPG
CCHHHHHHHHHHHHCEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LVNLDFADIRTVMQNGGVAMIGLGESDGENKAVESVQKALRSPLLDVDISGATSALVNVV
EEECCHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHC
GGPDMTISEAESVVQEVYSRIDSNARLIWGAQVDPDLEKTVRTMIVVTGVTSAQIYGHGN
CCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHEEEEECCCEEEEEECCC
DKDITYKYGIDFVE
CCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]