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The map label for this gene is modB [H]

Identifier: 21226829

GI number: 21226829

Start: 874974

End: 875639

Strand: Direct

Name: modB [H]

Synonym: MM_0727

Alternate gene names: 21226829

Gene position: 874974-875639 (Clockwise)

Preceding gene: 21226828

Following gene: 21226830

Centisome position: 21.36

GC content: 47.3

Gene sequence:

>666_bases
ATGGAAATGTTTCAGGTGGTCATGAGCCCTCTTTTGCTTACTCTCAAAATTGCCGCAGTTTCAACCTTCTTTGTGACATT
TCTGGGTATTCTGATCGCCTATGTGCTGGCAAAAAAAGAGTTTAGCGGAAAATGGCTGGCTGATGCGCTCGTGACCCTTC
CCCTTATTCTGCCACCAACTGTAACCGGTTATATTCTGGTTATTCTCCTCGGTAAAAACGGAATTTTAGGAAATATCTTT
ACCGAAATTACGGGAAAAGGCATACTTTTTACCTGGCAGGCAGCAGCCATTGCAGCCTTTGTAGTCTCTTTGCCCCTGAT
GGTAAAAACTGCCGCCTCAGCCATAGGGACTGTGGACAGGAGTGTTGAGGAAGCAGCCCGTATCCTCGGGAGAAACGAAC
TGGAAACTGCTCTCTTCATAACCCTGCCTCTTGCAAAAAAAGGCGTCATCGCAGGCTGTATTCTGAGTTTTGCAAGAGCA
GTCGGAGAGTTTGGGGCAACCCTGATGGTTGCTGGAAATATTCCGGGAAAGACAGGCACAATGCCTCTTTCCATCTATGG
GGCATACCAGACCGGAAATAATGAACTTGCCAGCCTGCTTGTGATAGTTCTGGTTGCCATATCCTTCCTGACCATTGCAG
CAACCAGCAGGCTTGCTGAAAAATAA

Upstream 100 bases:

>100_bases
AAATCAAAATTACAGATTGAAGGACTTTGTAAATTGAAAAAGTAAGGATAAGATTCAGGCTTTTAACCAGAACAGGGCCT
GAAAATTTGGAAGGGATTTA

Downstream 100 bases:

>100_bases
GAGGTGAAGGCTGAATGACTATTGAAGTTGACATTGAGAAGGAATTCTACGGAAGAAAACATGGGAAGAAAGGAGAAAAC
CCGAGCTTTTCAATGAACTG

Product: molybdenum ABC transporter permease

Products: ADP; phosphate; MoO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MEMFQVVMSPLLLTLKIAAVSTFFVTFLGILIAYVLAKKEFSGKWLADALVTLPLILPPTVTGYILVILLGKNGILGNIF
TEITGKGILFTWQAAAIAAFVVSLPLMVKTAASAIGTVDRSVEEAARILGRNELETALFITLPLAKKGVIAGCILSFARA
VGEFGATLMVAGNIPGKTGTMPLSIYGAYQTGNNELASLLVIVLVAISFLTIAATSRLAEK

Sequences:

>Translated_221_residues
MEMFQVVMSPLLLTLKIAAVSTFFVTFLGILIAYVLAKKEFSGKWLADALVTLPLILPPTVTGYILVILLGKNGILGNIF
TEITGKGILFTWQAAAIAAFVVSLPLMVKTAASAIGTVDRSVEEAARILGRNELETALFITLPLAKKGVIAGCILSFARA
VGEFGATLMVAGNIPGKTGTMPLSIYGAYQTGNNELASLLVIVLVAISFLTIAATSRLAEK
>Mature_221_residues
MEMFQVVMSPLLLTLKIAAVSTFFVTFLGILIAYVLAKKEFSGKWLADALVTLPLILPPTVTGYILVILLGKNGILGNIF
TEITGKGILFTWQAAAIAAFVVSLPLMVKTAASAIGTVDRSVEEAARILGRNELETALFITLPLAKKGVIAGCILSFARA
VGEFGATLMVAGNIPGKTGTMPLSIYGAYQTGNNELASLLVIVLVAISFLTIAATSRLAEK

Specific function: could be part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786980, Length=211, Percent_Identity=39.3364928909953, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788764, Length=208, Percent_Identity=32.6923076923077, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082099, Length=219, Percent_Identity=29.2237442922374, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787369, Length=175, Percent_Identity=32.5714285714286, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787080, Length=157, Percent_Identity=33.7579617834395, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23276; Mature: 23276

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMFQVVMSPLLLTLKIAAVSTFFVTFLGILIAYVLAKKEFSGKWLADALVTLPLILPPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
VTGYILVILLGKNGILGNIFTEITGKGILFTWQAAAIAAFVVSLPLMVKTAASAIGTVDR
HHHHEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVEEAARILGRNELETALFITLPLAKKGVIAGCILSFARAVGEFGATLMVAGNIPGKTGT
HHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
MPLSIYGAYQTGNNELASLLVIVLVAISFLTIAATSRLAEK
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEMFQVVMSPLLLTLKIAAVSTFFVTFLGILIAYVLAKKEFSGKWLADALVTLPLILPPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
VTGYILVILLGKNGILGNIFTEITGKGILFTWQAAAIAAFVVSLPLMVKTAASAIGTVDR
HHHHEEEEEECCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVEEAARILGRNELETALFITLPLAKKGVIAGCILSFARAVGEFGATLMVAGNIPGKTGT
HHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
MPLSIYGAYQTGNNELASLLVIVLVAISFLTIAATSRLAEK
CEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; MoO42- [Periplasm]; H2O [C]

Specific reaction: ATP + MoO42- [Periplasm] + H2O = ADP + phosphate + MoO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]