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The map label for this gene is 212225034

Identifier: 212225034

GI number: 212225034

Start: 1767180

End: 1769162

Strand: Reverse

Name: 212225034

Synonym: TON_1882

Alternate gene names: NA

Gene position: 1769162-1767180 (Counterclockwise)

Preceding gene: 212225035

Following gene: 212225033

Centisome position: 95.75

GC content: 53.2

Gene sequence:

>1983_bases
ATGGAGCTTGAGAAGTTCATCAACCACCTCAAGGTTCTCGTAGAGTACGAGAGAAAGGCCGAGATAGAAGCCATGAGGGC
AGAGATGAAAAGGCTAAGCGGCAGAGAGCGTGAGAAGGTAGGCAGAGCAATCCTTGGCCTGAACGGCAAAATAATCGGGG
AAGAACTCGGCTACTTCCTGGTAAAATACGGTCGAGATCGGGAAATTAAGACGGAAATAGGCGTAGGGGATTTGGTGGTT
ATCAGCAAACGCGATCCCCTGAAGAGCGATCTAGTTGGAACCGTCGTAGAGAAGGGGAAGCGATTCATTACAGTCGCCCT
TGAAACTGTCCCGGAATGGGCGCTTAAGGGGATAAGGCTAGACCTCTACGCCAACGATATCACATTCAAGCGCTGGATTG
AAAACCTTGAACACCTCCATGAGGGCGGAAAGAGGGCACTGGAGTTCTATCTCGGCCTAAGGGATCCGGAAGAAAGTGAG
CCGGTCGAGTTTGATCCGATCGATAAAAGCCTGAACGCGAGTCAGAGGAGAGCAATCAGCCAGGCACTCGGGAGCCCCAA
CTTCTTCCTCATCCACGGGCCTTTTGGAACGGGCAAAACCAGAACGCTGGCCGAGCTGATAAGGCAGGAAGTGGAGCGCG
GCCACAAGGTTCTTGCAACGGCAGAGAGCAACGTGGCTGTGGACAACCTCGTTGAGCGATTAGCAGAATCGGGCCTGAAA
ATCGTCCGGATTGGACACCCAAGCCGCGTTTCCAAACACCTCCACGAGACAACTCTTGCATATCTCATGACCAAGCATGA
CCTATACAGCGAGCTGAGAGAACTCCGAGTCACGGCACAGAACCTCGCGGAAAAGCGTGACACCTTCACAAAGCCCCTGC
CGAAGTACAGGCGCGGGTTGACCGACATTGAAATCCTTGCGTTGTCGAGGAGGAGGCGGGGCACGAGAGGGGTACCGGCA
AAACTCATCAGGGAGATGGCCAACTGGATAAAGCTCAACAAGCTCGTCCAGAAGGCCTTCGACGACGCCAGAAAGCTGGA
GGAGAGAATAGCCAGAGAGATAATTCAGGAGGCAGACGTTGTTCTCACCACCAACGCTTCGGCCGGGCTGGAGGTAATCG
GCTACGCAGACTACGATGTGGCCATCATAGATGAGGCGACCCAGGCGACCATACCAAGCGTGCTAATACCTATAAACCGT
GCCAAACGCTTCGTTTTAGCGGGCGACCACAGGCAGCTGCCGCCGACAATACTGAGTGAGAAGGCGCGGGAGCTCAGCAG
GACACTTTTTGAGGGACTGATTGAGCGCTATCCTGAGGACAGTGCTATGCTGACCGTTCAGTACAGGATGAACGAGAGGC
TGATGGAATTTCCGAACCGGGAGTTCTACGATGGGAAAATAAAGGCAGCACCCGGAGTTAAGTGCATCACTCTCACAGAT
CTCGGAATTAAGTGCCCCAATTTTGGGGAACCATGGGATGAAATCCTGAAAGCGGGCAATGTGCTCGTTTTTATAGACAC
ATCCAAACACCCGGAGAAGTGGGAGAGGCAGAGGCGCGGGAGCGAAAGCAGGGAGAACCCACTTGAGGCGAGGATAGTGG
CCGAGACCGTTGAGAAGCTCCTCGAGATGGGCGTCAAGCCAGAGTGGATTGGCGTGATAACGCCGTACGACGACCAGCGT
GACTTAATCAGCTCACTCGTTCCCGAGGAGATAGAGGTCAGAACCGTGGATGGCTATCAGGGCAGGGAAAAGGAAGTCAT
AATCCTCTCCTTCGTGCGCTCAAACGAGAGGGGCGAGGTTGGCTTCCTGAAGGATTTGAGAAGATTAAACGTCTCGCTGA
CGAGGGCAAAGAGGAAGCTGATAGTGGTTGGGGATTCCGAAACTTTAAGCGTTCATTCAACTTACAAAAGGTTCATCGAG
TTCGTGAAAGCTGAGGGTAGGTTCGTTGAGATTGGAAATGATTTTAAGACCAACGGGGGATGA

Upstream 100 bases:

>100_bases
ATGATGAGGGAAGTTTCGTCCGAGCGGTGAGGAAACTCGCATGGGCTGACCAACCCTCAACCTTTTAAGACGTTCTTCTT
TCCTCCGCTTGGGAGCGAGA

Downstream 100 bases:

>100_bases
GGAGCCATGTTCCTATTTACCAAGAACTTCGACGAGCAGAAGGCCAGGGCGATGGCAGGCCTTAGGAAGGCACTGGAAGA
GGGCAAGGTGGATGAGGACA

Product: DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MELEKFINHLKVLVEYERKAEIEAMRAEMKRLSGREREKVGRAILGLNGKIIGEELGYFLVKYGRDREIKTEIGVGDLVV
ISKRDPLKSDLVGTVVEKGKRFITVALETVPEWALKGIRLDLYANDITFKRWIENLEHLHEGGKRALEFYLGLRDPEESE
PVEFDPIDKSLNASQRRAISQALGSPNFFLIHGPFGTGKTRTLAELIRQEVERGHKVLATAESNVAVDNLVERLAESGLK
IVRIGHPSRVSKHLHETTLAYLMTKHDLYSELRELRVTAQNLAEKRDTFTKPLPKYRRGLTDIEILALSRRRRGTRGVPA
KLIREMANWIKLNKLVQKAFDDARKLEERIAREIIQEADVVLTTNASAGLEVIGYADYDVAIIDEATQATIPSVLIPINR
AKRFVLAGDHRQLPPTILSEKARELSRTLFEGLIERYPEDSAMLTVQYRMNERLMEFPNREFYDGKIKAAPGVKCITLTD
LGIKCPNFGEPWDEILKAGNVLVFIDTSKHPEKWERQRRGSESRENPLEARIVAETVEKLLEMGVKPEWIGVITPYDDQR
DLISSLVPEEIEVRTVDGYQGREKEVIILSFVRSNERGEVGFLKDLRRLNVSLTRAKRKLIVVGDSETLSVHSTYKRFIE
FVKAEGRFVEIGNDFKTNGG

Sequences:

>Translated_660_residues
MELEKFINHLKVLVEYERKAEIEAMRAEMKRLSGREREKVGRAILGLNGKIIGEELGYFLVKYGRDREIKTEIGVGDLVV
ISKRDPLKSDLVGTVVEKGKRFITVALETVPEWALKGIRLDLYANDITFKRWIENLEHLHEGGKRALEFYLGLRDPEESE
PVEFDPIDKSLNASQRRAISQALGSPNFFLIHGPFGTGKTRTLAELIRQEVERGHKVLATAESNVAVDNLVERLAESGLK
IVRIGHPSRVSKHLHETTLAYLMTKHDLYSELRELRVTAQNLAEKRDTFTKPLPKYRRGLTDIEILALSRRRRGTRGVPA
KLIREMANWIKLNKLVQKAFDDARKLEERIAREIIQEADVVLTTNASAGLEVIGYADYDVAIIDEATQATIPSVLIPINR
AKRFVLAGDHRQLPPTILSEKARELSRTLFEGLIERYPEDSAMLTVQYRMNERLMEFPNREFYDGKIKAAPGVKCITLTD
LGIKCPNFGEPWDEILKAGNVLVFIDTSKHPEKWERQRRGSESRENPLEARIVAETVEKLLEMGVKPEWIGVITPYDDQR
DLISSLVPEEIEVRTVDGYQGREKEVIILSFVRSNERGEVGFLKDLRRLNVSLTRAKRKLIVVGDSETLSVHSTYKRFIE
FVKAEGRFVEIGNDFKTNGG
>Mature_660_residues
MELEKFINHLKVLVEYERKAEIEAMRAEMKRLSGREREKVGRAILGLNGKIIGEELGYFLVKYGRDREIKTEIGVGDLVV
ISKRDPLKSDLVGTVVEKGKRFITVALETVPEWALKGIRLDLYANDITFKRWIENLEHLHEGGKRALEFYLGLRDPEESE
PVEFDPIDKSLNASQRRAISQALGSPNFFLIHGPFGTGKTRTLAELIRQEVERGHKVLATAESNVAVDNLVERLAESGLK
IVRIGHPSRVSKHLHETTLAYLMTKHDLYSELRELRVTAQNLAEKRDTFTKPLPKYRRGLTDIEILALSRRRRGTRGVPA
KLIREMANWIKLNKLVQKAFDDARKLEERIAREIIQEADVVLTTNASAGLEVIGYADYDVAIIDEATQATIPSVLIPINR
AKRFVLAGDHRQLPPTILSEKARELSRTLFEGLIERYPEDSAMLTVQYRMNERLMEFPNREFYDGKIKAAPGVKCITLTD
LGIKCPNFGEPWDEILKAGNVLVFIDTSKHPEKWERQRRGSESRENPLEARIVAETVEKLLEMGVKPEWIGVITPYDDQR
DLISSLVPEEIEVRTVDGYQGREKEVIILSFVRSNERGEVGFLKDLRRLNVSLTRAKRKLIVVGDSETLSVHSTYKRFIE
FVKAEGRFVEIGNDFKTNGG

Specific function: Unknown

COG id: COG1112

COG function: function code L; Superfamily I DNA and RNA helicases and helicase subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA2/NAM7 helicase family [H]

Homologues:

Organism=Homo sapiens, GI119392094, Length=677, Percent_Identity=33.5302806499261, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI18375673, Length=496, Percent_Identity=32.0564516129032, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI122937299, Length=316, Percent_Identity=33.5443037974684, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI113722133, Length=556, Percent_Identity=28.0575539568345, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI156105693, Length=535, Percent_Identity=27.1028037383178, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI156105695, Length=535, Percent_Identity=27.1028037383178, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI194272168, Length=543, Percent_Identity=27.255985267035, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI14211540, Length=543, Percent_Identity=27.255985267035, Blast_Score=120, Evalue=5e-27,
Organism=Homo sapiens, GI254826809, Length=310, Percent_Identity=32.5806451612903, Blast_Score=116, Evalue=8e-26,
Organism=Homo sapiens, GI14251207, Length=341, Percent_Identity=31.0850439882698, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI255759908, Length=315, Percent_Identity=32.0634920634921, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI255759910, Length=316, Percent_Identity=31.9620253164557, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI28626521, Length=301, Percent_Identity=26.578073089701, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI255759906, Length=270, Percent_Identity=30, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17510163, Length=568, Percent_Identity=30.9859154929577, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71981659, Length=535, Percent_Identity=27.4766355140187, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17533985, Length=326, Percent_Identity=33.4355828220859, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17533987, Length=326, Percent_Identity=33.4355828220859, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17531515, Length=566, Percent_Identity=24.9116607773852, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531513, Length=566, Percent_Identity=24.9116607773852, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI133958006, Length=320, Percent_Identity=25.9375, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538027, Length=390, Percent_Identity=25.3846153846154, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17535407, Length=263, Percent_Identity=27.3764258555133, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322835, Length=699, Percent_Identity=31.0443490701001, Blast_Score=226, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6323726, Length=512, Percent_Identity=35.15625, Blast_Score=213, Evalue=9e-56,
Organism=Saccharomyces cerevisiae, GI6323462, Length=557, Percent_Identity=29.2639138240575, Blast_Score=172, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321024, Length=516, Percent_Identity=28.8759689922481, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6321958, Length=308, Percent_Identity=33.7662337662338, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI18859757, Length=494, Percent_Identity=31.9838056680162, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24660647, Length=506, Percent_Identity=27.4703557312253, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI221330969, Length=507, Percent_Identity=27.810650887574, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281363531, Length=558, Percent_Identity=27.0609318996416, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281363529, Length=558, Percent_Identity=27.0609318996416, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24640932, Length=358, Percent_Identity=30.1675977653631, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161077698, Length=358, Percent_Identity=30.1675977653631, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45550425, Length=341, Percent_Identity=29.0322580645161, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24649577, Length=492, Percent_Identity=25, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI62471854, Length=521, Percent_Identity=25.5278310940499, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24656854, Length=521, Percent_Identity=25.5278310940499, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR004483 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 75226; Mature: 75226

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEKFINHLKVLVEYERKAEIEAMRAEMKRLSGREREKVGRAILGLNGKIIGEELGYFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEHHHHHHHH
VKYGRDREIKTEIGVGDLVVISKRDPLKSDLVGTVVEKGKRFITVALETVPEWALKGIRL
HHCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCEEE
DLYANDITFKRWIENLEHLHEGGKRALEFYLGLRDPEESEPVEFDPIDKSLNASQRRAIS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
QALGSPNFFLIHGPFGTGKTRTLAELIRQEVERGHKVLATAESNVAVDNLVERLAESGLK
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCE
IVRIGHPSRVSKHLHETTLAYLMTKHDLYSELRELRVTAQNLAEKRDTFTKPLPKYRRGL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
TDIEILALSRRRRGTRGVPAKLIREMANWIKLNKLVQKAFDDARKLEERIAREIIQEADV
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VLTTNASAGLEVIGYADYDVAIIDEATQATIPSVLIPINRAKRFVLAGDHRQLPPTILSE
EEEECCCCCEEEEEECCCCEEEECCCHHHCCCCEEEEHHHCCEEEEECCCCCCCHHHHHH
KARELSRTLFEGLIERYPEDSAMLTVQYRMNERLMEFPNREFYDGKIKAAPGVKCITLTD
HHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHCCCCCCCCCEEECCCCCEEEEEEC
LGIKCPNFGEPWDEILKAGNVLVFIDTSKHPEKWERQRRGSESRENPLEARIVAETVEKL
CCCCCCCCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LEMGVKPEWIGVITPYDDQRDLISSLVPEEIEVRTVDGYQGREKEVIILSFVRSNERGEV
HHCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCC
GFLKDLRRLNVSLTRAKRKLIVVGDSETLSVHSTYKRFIEFVKAEGRFVEIGNDFKTNGG
HHHHHHHHHHHHHEECCCEEEEECCCCEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MELEKFINHLKVLVEYERKAEIEAMRAEMKRLSGREREKVGRAILGLNGKIIGEELGYFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEHHHHHHHH
VKYGRDREIKTEIGVGDLVVISKRDPLKSDLVGTVVEKGKRFITVALETVPEWALKGIRL
HHCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCEEE
DLYANDITFKRWIENLEHLHEGGKRALEFYLGLRDPEESEPVEFDPIDKSLNASQRRAIS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
QALGSPNFFLIHGPFGTGKTRTLAELIRQEVERGHKVLATAESNVAVDNLVERLAESGLK
HHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCE
IVRIGHPSRVSKHLHETTLAYLMTKHDLYSELRELRVTAQNLAEKRDTFTKPLPKYRRGL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
TDIEILALSRRRRGTRGVPAKLIREMANWIKLNKLVQKAFDDARKLEERIAREIIQEADV
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VLTTNASAGLEVIGYADYDVAIIDEATQATIPSVLIPINRAKRFVLAGDHRQLPPTILSE
EEEECCCCCEEEEEECCCCEEEECCCHHHCCCCEEEEHHHCCEEEEECCCCCCCHHHHHH
KARELSRTLFEGLIERYPEDSAMLTVQYRMNERLMEFPNREFYDGKIKAAPGVKCITLTD
HHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHCCCCCCCCCEEECCCCCEEEEEEC
LGIKCPNFGEPWDEILKAGNVLVFIDTSKHPEKWERQRRGSESRENPLEARIVAETVEKL
CCCCCCCCCCCHHHHHHHCCEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LEMGVKPEWIGVITPYDDQRDLISSLVPEEIEVRTVDGYQGREKEVIILSFVRSNERGEV
HHCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCC
GFLKDLRRLNVSLTRAKRKLIVVGDSETLSVHSTYKRFIEFVKAEGRFVEIGNDFKTNGG
HHHHHHHHHHHHHEECCCEEEEECCCCEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]