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The map label for this gene is speH

Identifier: 212224893

GI number: 212224893

Start: 1607696

End: 1608121

Strand: Reverse

Name: speH

Synonym: TON_1742

Alternate gene names: 212224893

Gene position: 1608121-1607696 (Counterclockwise)

Preceding gene: 212224909

Following gene: 212224890

Centisome position: 87.04

GC content: 52.35

Gene sequence:

>426_bases
ATGGAGACGATAGGGTTTCACTACGTGGTTGAGGCTGCAGGCTGCGATCCAGAGATCCTCGGTAACGCTGACAAGATAAG
ACAGATATTCCTCGAGGCTGCCAAAGTAGGCAAAATGGAGGTCAAAGCGAGCTATTTCTTCAAGTTCTCACCGACCGGTG
TCAGCGGAGTGGTCATAGTTGCAGAGAGCCACATCTCGATTCACACCTGGCCGGAGAAGGGCTACGCCGCTCTCGACGTC
TACACCTGTGGAACCACCGCGGATCCGGAAAAAGCCGTTGACTACATCCTCGACAAGATAAAGGCCCAGTATGCTCACGT
TTCAGAGATCAAGAGAGGTATCGAGGAGGACGACGAGACCTTCACCCACATGATTCTTACCTGGGAAGAGAAGCTCGAGA
GAAAGAACGGAGATGAGAAGAGCTGA

Upstream 100 bases:

>100_bases
TTCTGAACAGTTCAACGCTCGAAAGACCCGCCCAGGTCTCTTCGCTTCAGGGCTTAACTTTAAAAAGGGTAGGTTCTACT
GGAACAACAGGTGAGAGGCC

Downstream 100 bases:

>100_bases
ACCTCAGAGTAGACTTTTAATCTCTTCTATCTTCTTCTCCAGGGTGGTTGTTACCTCCCTTACCTTCTCGAGCTTGTTCT
TAAGCTCTTCGTTCTCACTT

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
METIGFHYVVEAAGCDPEILGNADKIRQIFLEAAKVGKMEVKASYFFKFSPTGVSGVVIVAESHISIHTWPEKGYAALDV
YTCGTTADPEKAVDYILDKIKAQYAHVSEIKRGIEEDDETFTHMILTWEEKLERKNGDEKS

Sequences:

>Translated_141_residues
METIGFHYVVEAAGCDPEILGNADKIRQIFLEAAKVGKMEVKASYFFKFSPTGVSGVVIVAESHISIHTWPEKGYAALDV
YTCGTTADPEKAVDYILDKIKAQYAHVSEIKRGIEEDDETFTHMILTWEEKLERKNGDEKS
>Mature_141_residues
METIGFHYVVEAAGCDPEILGNADKIRQIFLEAAKVGKMEVKASYFFKFSPTGVSGVVIVAESHISIHTWPEKGYAALDV
YTCGTTADPEKAVDYILDKIKAQYAHVSEIKRGIEEDDETFTHMILTWEEKLERKNGDEKS

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_THEON (B6YV04)

Other databases:

- EMBL:   CP000855
- RefSeq:   YP_002308129.1
- GeneID:   7017411
- GenomeReviews:   CP000855_GR
- KEGG:   ton:TON_1742
- HOGENOM:   HBG485559
- OMA:   VEAAGCD
- ProtClustDB:   PRK04025
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 15789; Mature: 15789

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIGFHYVVEAAGCDPEILGNADKIRQIFLEAAKVGKMEVKASYFFKFSPTGVSGVVIV
CCCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEE
AESHISIHTWPEKGYAALDVYTCGTTADPEKAVDYILDKIKAQYAHVSEIKRGIEEDDET
EECCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
FTHMILTWEEKLERKNGDEKS
HHHHEEEHHHHHHHCCCCCCC
>Mature Secondary Structure
METIGFHYVVEAAGCDPEILGNADKIRQIFLEAAKVGKMEVKASYFFKFSPTGVSGVVIV
CCCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEE
AESHISIHTWPEKGYAALDVYTCGTTADPEKAVDYILDKIKAQYAHVSEIKRGIEEDDET
EECCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
FTHMILTWEEKLERKNGDEKS
HHHHEEEHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA