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The map label for this gene is cls [C]

Identifier: 212224875

GI number: 212224875

Start: 1591993

End: 1592757

Strand: Reverse

Name: cls [C]

Synonym: TON_1724

Alternate gene names: 212224875

Gene position: 1592757-1591993 (Counterclockwise)

Preceding gene: 212224877

Following gene: 212224874

Centisome position: 86.21

GC content: 51.63

Gene sequence:

>765_bases
ATGGTGGTACGCGTGAAGAAAGCTCTGGTATTTCTGCTCATCATAACTGTTCTATCAGCGGGCTGTCTTGGTGGAACTCA
AACCGTGACAACCACCGTAACTGAAATCCAGAACCACACACTCACCGAAACCGTAACCGAAACCCATACCGAGGTGAAAG
TGATAGAGCCTGGAATCAACGTCACCGAGCTGACCGAGAATCTTAGCCTGTGCGTCTCAAAGCTCTCCGAGCTCAACTCC
ACATTGGCCGAAGAGGAAGGAGAGCTCAGCTCGTTGAAGGCCAAATACCAGAGCTGTCTGATTCAGCAGGCCCTTGGAAA
TGAGGCAGGTTTTGAAATACTCCTCGATAATGAATACTACTATGAGGTTCTCAACACCATAAACAACGCCGGTGAGAGCA
TCTATGTAATGATGTTCTCCATGAAGTACGACCCCGCGGACAGCTTCGACTGGGCAAACGATCTCATAAGAGCCCTGGCG
GAGGCCGAAAAGAGGGGAGTCAGCGTTCATGTCCTCCTCGAGGACTCCTCGGACATCAATCAGGCCGCCTACGATTACCT
GAAAGCCAACGGCGTGGATGTTTCTTTTGACTCGCCCGAAACGACGCTTCACGCTAAGGTGGTGGTGATAGACGGGAAGA
CAGTCTTCCTCGGGAGTCACAACTGGAGCGAGAGCGCCCTCTACTGGAACCACGAGGTCAGCATCAAAATAGTCTCCGAA
GATCTCGCCCAGAGCCTGATTAACTACTTCTGGAGCATCCGCTAA

Upstream 100 bases:

>100_bases
ACGGAACCCACTATTATGCGATTTCAGTCTCAAAAATATGAGAGTCTTAACGGTTGCCCTACGTTAAGGTTAAATTCACA
AGTTGGATGTACACCATTGG

Downstream 100 bases:

>100_bases
GGCTTTAAGCCCTGCTCTCAACTTTTTTCGGTGTTGAAGATGTTTGAGTCACTGAAGAAGATTTACTGGAAGTGGCGCTC
CCGCTGCCCCTTCGTCAGAA

Product: phospholipase D-related protein

Products: Biphosphatidylglycerol; Glycerol. [C]

Alternate protein names: Phospholipase D-Related Protein

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MVVRVKKALVFLLIITVLSAGCLGGTQTVTTTVTEIQNHTLTETVTETHTEVKVIEPGINVTELTENLSLCVSKLSELNS
TLAEEEGELSSLKAKYQSCLIQQALGNEAGFEILLDNEYYYEVLNTINNAGESIYVMMFSMKYDPADSFDWANDLIRALA
EAEKRGVSVHVLLEDSSDINQAAYDYLKANGVDVSFDSPETTLHAKVVVIDGKTVFLGSHNWSESALYWNHEVSIKIVSE
DLAQSLINYFWSIR

Sequences:

>Translated_254_residues
MVVRVKKALVFLLIITVLSAGCLGGTQTVTTTVTEIQNHTLTETVTETHTEVKVIEPGINVTELTENLSLCVSKLSELNS
TLAEEEGELSSLKAKYQSCLIQQALGNEAGFEILLDNEYYYEVLNTINNAGESIYVMMFSMKYDPADSFDWANDLIRALA
EAEKRGVSVHVLLEDSSDINQAAYDYLKANGVDVSFDSPETTLHAKVVVIDGKTVFLGSHNWSESALYWNHEVSIKIVSE
DLAQSLINYFWSIR
>Mature_254_residues
MVVRVKKALVFLLIITVLSAGCLGGTQTVTTTVTEIQNHTLTETVTETHTEVKVIEPGINVTELTENLSLCVSKLSELNS
TLAEEEGELSSLKAKYQSCLIQQALGNEAGFEILLDNEYYYEVLNTINNAGESIYVMMFSMKYDPADSFDWANDLIRALA
EAEKRGVSVHVLLEDSSDINQAAYDYLKANGVDVSFDSPETTLHAKVVVIDGKTVFLGSHNWSESALYWNHEVSIKIVSE
DLAQSLINYFWSIR

Specific function: Catalyzes The Reversible Phosphatidyl Group Transfer From One Phosphatidylglycerol Molecule To Another To Form Cardiolipin (Cl) (Diphosphatidylglycerol) And Glycerol. Affects Resistance To The Gyrase Inhibitor Novobiocin. [C]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.8.- [C]

Molecular weight: Translated: 28184; Mature: 28184

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRVKKALVFLLIITVLSAGCLGGTQTVTTTVTEIQNHTLTETVTETHTEVKVIEPGIN
CEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCC
VTELTENLSLCVSKLSELNSTLAEEEGELSSLKAKYQSCLIQQALGNEAGFEILLDNEYY
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
YEVLNTINNAGESIYVMMFSMKYDPADSFDWANDLIRALAEAEKRGVSVHVLLEDSSDIN
HHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
QAAYDYLKANGVDVSFDSPETTLHAKVVVIDGKTVFLGSHNWSESALYWNHEVSIKIVSE
HHHHHHHHCCCEEEECCCCCCEEEEEEEEEECCEEEEECCCCCCCEEEECCEEEEEEHHH
DLAQSLINYFWSIR
HHHHHHHHHHHCCC
>Mature Secondary Structure
MVVRVKKALVFLLIITVLSAGCLGGTQTVTTTVTEIQNHTLTETVTETHTEVKVIEPGIN
CEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCC
VTELTENLSLCVSKLSELNSTLAEEEGELSSLKAKYQSCLIQQALGNEAGFEILLDNEYY
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
YEVLNTINNAGESIYVMMFSMKYDPADSFDWANDLIRALAEAEKRGVSVHVLLEDSSDIN
HHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
QAAYDYLKANGVDVSFDSPETTLHAKVVVIDGKTVFLGSHNWSESALYWNHEVSIKIVSE
HHHHHHHHCCCEEEECCCCCCEEEEEEEEEECCEEEEECCCCCCCEEEECCEEEEEEHHH
DLAQSLINYFWSIR
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Phosphatidylglycerol [C]

Specific reaction: 2 Phosphatidylglycerol = Biphosphatidylglycerol + Glycerol. [C]

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA