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The map label for this gene is gcp [H]

Identifier: 212224785

GI number: 212224785

Start: 1493599

End: 1494576

Strand: Reverse

Name: gcp [H]

Synonym: TON_1634

Alternate gene names: 212224785

Gene position: 1494576-1493599 (Counterclockwise)

Preceding gene: 212224786

Following gene: 212224784

Centisome position: 80.89

GC content: 51.84

Gene sequence:

>978_bases
ATGATAGCTCTTGGCATAGAGGGGACGGCACACACTCTTGGCATAGGTATAGTCACCGAGAAGAAAGTTCTCGCCAACGT
ATTCGATACTCTCACTACTGAAAAGGGTGGAATCCACCCAAAGGAAGCCGCCGAACACCATGCAAGGCTTTTGAAGCCTC
TTCTGAGAAAGGCCCTTGACGAGGCGGGAATAACTATCGAGGACGTTGACATGATAGCCTTCTCCCAGGGACCAGGTCTT
GGGCCTTCTTTGCGAGTTGTTGCCACGGCTGCACGAGCTCTTGCCATAAAGCATAACAAACCGATAATCGGTGTGAATCA
CTGCATAGCTCACGTTGAGATAGCTAAGATGTTCGGTGTTAAAGACCCCGTTGGTCTCTACGTGAGCGGTGGAAACACCC
AGGTTCTGGCGTTGGAGGGAGGCCGCTACCGAGTCTTCGGTGAAACGCTTGATATTGGCATAGGTAACGCTATAGACACC
TTTGCGCGCGAGATTGGGATAGGTTTCCCTGGAGGACCCAAGATAGAGAAGCTTGCCCTGGAGGGAGAGAAATACATTGA
GCTCCCCTATGCGGTTAAAGGTATGGATTTGAGCTTCTCCGGAATACTCACTGAGGCCGTCCGGAAGTACCGCACGGGCC
GGTATCGGGTTGAGGATCTTGCCTATTCTTTTCAGGAGACTGCATTTGCAGCGCTCGTTGAGGTCACCGAGAGGGCCGTT
GCCCACACCGGCAAGGATGAGGTCGTTCTCGTTGGAGGCGTCGCCGCGAACAACAGATTGAGGGAGATGCTTAGAATAAT
GACCGAGGACAGGGGGATAAAGTTCTTCGTTCCGCCCTACGATCTCTGCAGAGACAACGGGGCCATGATAGCTTACACTG
GATTGAGGATGTATCTTGGCGGTGTTAAGTTCAATCTCGAGGAAACTGTGGTAAAGCAGAAGTTTAGGACGGATGAGGTG
GAGGTTGTATGGAGTTAA

Upstream 100 bases:

>100_bases
ACTGCATGGACGGATTTTGTGACCTTCGAGAAGCACGTCCATCGTCCTCCTCAAGTCCACTCTCGATAACCTTTTATACT
ATTTTTACACTCCACCCTTG

Downstream 100 bases:

>100_bases
AGGTTTCAATCTGGATCTTTTTTATTGATATCGTACTGTTCATCGTTATCGGATATTCCGCGCTCTACGCCCTCAGAAGG
ATATCACGTTACGGTGAACC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MIALGIEGTAHTLGIGIVTEKKVLANVFDTLTTEKGGIHPKEAAEHHARLLKPLLRKALDEAGITIEDVDMIAFSQGPGL
GPSLRVVATAARALAIKHNKPIIGVNHCIAHVEIAKMFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDT
FAREIGIGFPGGPKIEKLALEGEKYIELPYAVKGMDLSFSGILTEAVRKYRTGRYRVEDLAYSFQETAFAALVEVTERAV
AHTGKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYLGGVKFNLEETVVKQKFRTDEV
EVVWS

Sequences:

>Translated_325_residues
MIALGIEGTAHTLGIGIVTEKKVLANVFDTLTTEKGGIHPKEAAEHHARLLKPLLRKALDEAGITIEDVDMIAFSQGPGL
GPSLRVVATAARALAIKHNKPIIGVNHCIAHVEIAKMFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDT
FAREIGIGFPGGPKIEKLALEGEKYIELPYAVKGMDLSFSGILTEAVRKYRTGRYRVEDLAYSFQETAFAALVEVTERAV
AHTGKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYLGGVKFNLEETVVKQKFRTDEV
EVVWS
>Mature_325_residues
MIALGIEGTAHTLGIGIVTEKKVLANVFDTLTTEKGGIHPKEAAEHHARLLKPLLRKALDEAGITIEDVDMIAFSQGPGL
GPSLRVVATAARALAIKHNKPIIGVNHCIAHVEIAKMFGVKDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDT
FAREIGIGFPGGPKIEKLALEGEKYIELPYAVKGMDLSFSGILTEAVRKYRTGRYRVEDLAYSFQETAFAALVEVTERAV
AHTGKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYLGGVKFNLEETVVKQKFRTDEV
EVVWS

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI8923380, Length=329, Percent_Identity=49.2401215805471, Blast_Score=315, Evalue=4e-86,
Organism=Homo sapiens, GI116812636, Length=338, Percent_Identity=28.9940828402367, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789445, Length=328, Percent_Identity=36.890243902439, Blast_Score=176, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71995670, Length=333, Percent_Identity=45.3453453453453, Blast_Score=287, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI17557464, Length=329, Percent_Identity=27.6595744680851, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322891, Length=368, Percent_Identity=44.5652173913043, Blast_Score=275, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6320099, Length=323, Percent_Identity=31.8885448916409, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21357207, Length=343, Percent_Identity=48.1049562682216, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI20129063, Length=339, Percent_Identity=29.4985250737463, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022449
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35384; Mature: 35384

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALGIEGTAHTLGIGIVTEKKVLANVFDTLTTEKGGIHPKEAAEHHARLLKPLLRKALD
CEEEECCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EAGITIEDVDMIAFSQGPGLGPSLRVVATAARALAIKHNKPIIGVNHCIAHVEIAKMFGV
HHCCEEEECEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCEEEHHHHHHHHHHHHHHCC
KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDTFAREIGIGFPGGPKIEKLAL
CCCCEEEEECCCEEEEEEECCEEEEECCEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEE
EGEKYIELPYAVKGMDLSFSGILTEAVRKYRTGRYRVEDLAYSFQETAFAALVEVTERAV
CCCCEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
AHTGKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYLG
HHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCEEEEECHHHHHC
GVKFNLEETVVKQKFRTDEVEVVWS
CEEECHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MIALGIEGTAHTLGIGIVTEKKVLANVFDTLTTEKGGIHPKEAAEHHARLLKPLLRKALD
CEEEECCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EAGITIEDVDMIAFSQGPGLGPSLRVVATAARALAIKHNKPIIGVNHCIAHVEIAKMFGV
HHCCEEEECEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCEEEHHHHHHHHHHHHHHCC
KDPVGLYVSGGNTQVLALEGGRYRVFGETLDIGIGNAIDTFAREIGIGFPGGPKIEKLAL
CCCCEEEEECCCEEEEEEECCEEEEECCEEECCCCHHHHHHHHHHCCCCCCCCCCEEEEE
EGEKYIELPYAVKGMDLSFSGILTEAVRKYRTGRYRVEDLAYSFQETAFAALVEVTERAV
CCCCEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
AHTGKDEVVLVGGVAANNRLREMLRIMTEDRGIKFFVPPYDLCRDNGAMIAYTGLRMYLG
HHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCEEEEECHHHHHC
GVKFNLEETVVKQKFRTDEVEVVWS
CEEECHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA