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The map label for this gene is queC [H]

Identifier: 212224412

GI number: 212224412

Start: 1148299

End: 1149018

Strand: Reverse

Name: queC [H]

Synonym: TON_1263

Alternate gene names: 212224412

Gene position: 1149018-1148299 (Counterclockwise)

Preceding gene: 212224413

Following gene: 212224406

Centisome position: 62.19

GC content: 53.75

Gene sequence:

>720_bases
ATGAAGCGCGCAGTTGTGTTATTTTCCGGGGGGCTCGACTCGACGGCCTGCCTCTACTGGGCGAAGAGGAACTACGACGA
GGTGATAATGCTGACAGTAAACTACGGCAGCAATGAAGAGAAGGTCACTAATAGGGTCGCGGAATTCTTCTCGAAGGAGC
TGGACGTTCCGCTGAAAATAGTTAGGCTTGACTTTCTCGAGGAGTTCTCGAAGCTGAGGGGGACGACCTTGGTCGGCGGC
GAGACTCCAAAGGTGACCGCTGAAGAGCTCGAAGATATGGGCGTTGCACAGGAAACCGCGAAAAGCGTCTGGGTTCCAGC
AAGGAATGTCGTTCTCATCAGCGTCGCTGCTTCGCTCCTTGATGCGCTTGGTGGAGGCGATATAATAGTCGGCTTCAACG
CTGAAGAGGGAGCAACGTTCCCTGACAACACGCCCGAGTTCGTCGAGAGGATGAACGAGATGCTGAAGTACGGAGCGATG
GCGGAAGTTAGGGTCGTTGCCCCGCTCATAGACCTCGACAAGAAGGGAATCGCAGAACTCTTGAAAGAACTAGATGCAAA
GTACGAGTACTCTAACTCTTGCTACATGCCTAAGGGCTTCACGGAGGATGGCAAGCCTATACACTGCGGCGAGTGCGAGA
GCTGCGTCAGGAGGCATCGCGGTCTGATGGAAGCACTTGGAGAGGACAGAACCGTTTATGCCGTTGAACCGAAGATATAA

Upstream 100 bases:

>100_bases
CGAGGAGGAAGGCTTTGAGAGTATTGAGGAAATAGTTGGGCTGGCGCTGGAGTAGATTTTTAACCTTCAGTCCTCCTTTT
AATCTAAGCGAGGTGATAAC

Downstream 100 bases:

>100_bases
CTGCCTTTCTCCATCCTCTTTAGATTTTTAAAGACCTCTGGCCATACCACCGCAAGATTTATAAATACGCTCTCTACCCT
ATCCATTGGGCGTGGGGCGG

Product: putative transcription regulator

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKRAVVLFSGGLDSTACLYWAKRNYDEVIMLTVNYGSNEEKVTNRVAEFFSKELDVPLKIVRLDFLEEFSKLRGTTLVGG
ETPKVTAEELEDMGVAQETAKSVWVPARNVVLISVAASLLDALGGGDIIVGFNAEEGATFPDNTPEFVERMNEMLKYGAM
AEVRVVAPLIDLDKKGIAELLKELDAKYEYSNSCYMPKGFTEDGKPIHCGECESCVRRHRGLMEALGEDRTVYAVEPKI

Sequences:

>Translated_239_residues
MKRAVVLFSGGLDSTACLYWAKRNYDEVIMLTVNYGSNEEKVTNRVAEFFSKELDVPLKIVRLDFLEEFSKLRGTTLVGG
ETPKVTAEELEDMGVAQETAKSVWVPARNVVLISVAASLLDALGGGDIIVGFNAEEGATFPDNTPEFVERMNEMLKYGAM
AEVRVVAPLIDLDKKGIAELLKELDAKYEYSNSCYMPKGFTEDGKPIHCGECESCVRRHRGLMEALGEDRTVYAVEPKI
>Mature_239_residues
MKRAVVLFSGGLDSTACLYWAKRNYDEVIMLTVNYGSNEEKVTNRVAEFFSKELDVPLKIVRLDFLEEFSKLRGTTLVGG
ETPKVTAEELEDMGVAQETAKSVWVPARNVVLISVAASLLDALGGGDIIVGFNAEEGATFPDNTPEFVERMNEMLKYGAM
AEVRVVAPLIDLDKKGIAELLKELDAKYEYSNSCYMPKGFTEDGKPIHCGECESCVRRHRGLMEALGEDRTVYAVEPKI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=237, Percent_Identity=31.2236286919831, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 26474; Mature: 26474

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAVVLFSGGLDSTACLYWAKRNYDEVIMLTVNYGSNEEKVTNRVAEFFSKELDVPLKI
CCEEEEEEECCCCCHHEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHH
VRLDFLEEFSKLRGTTLVGGETPKVTAEELEDMGVAQETAKSVWVPARNVVLISVAASLL
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHH
DALGGGDIIVGFNAEEGATFPDNTPEFVERMNEMLKYGAMAEVRVVAPLIDLDKKGIAEL
HHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
LKELDAKYEYSNSCYMPKGFTEDGKPIHCGECESCVRRHRGLMEALGEDRTVYAVEPKI
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MKRAVVLFSGGLDSTACLYWAKRNYDEVIMLTVNYGSNEEKVTNRVAEFFSKELDVPLKI
CCEEEEEEECCCCCHHEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHH
VRLDFLEEFSKLRGTTLVGGETPKVTAEELEDMGVAQETAKSVWVPARNVVLISVAASLL
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHH
DALGGGDIIVGFNAEEGATFPDNTPEFVERMNEMLKYGAMAEVRVVAPLIDLDKKGIAEL
HHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
LKELDAKYEYSNSCYMPKGFTEDGKPIHCGECESCVRRHRGLMEALGEDRTVYAVEPKI
HHHHHCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA