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The map label for this gene is tdk [H]

Identifier: 212224382

GI number: 212224382

Start: 1124753

End: 1125331

Strand: Reverse

Name: tdk [H]

Synonym: TON_1233

Alternate gene names: 212224382

Gene position: 1125331-1124753 (Counterclockwise)

Preceding gene: 212224383

Following gene: 212224380

Centisome position: 60.91

GC content: 51.81

Gene sequence:

>579_bases
ATGCATCCGGGAGGGTTCTTGGAAGTCATCACGGGTCCAATGTTTGCGGGTAAAACAACGGAGCTGATTAAGCGCATAGA
ACGCCAGATGTTTGCAAAAAGAAAGGCAGCGCTCTTCAAACCTGCCATAGACAACAGGTACAGCGAGGATGAGATCGTTG
CCCACAACGGGCTGCGCTACGAAGCTTTTGTCATACCGACGGATGAAGAGGGTGTGAGAACGATAGGAGAAATAACCAAG
AGAGAGAACTTTGAGGTCATAGGAATTGACGAGGTGCAGTTCTTTCCGATGAGCATCGTTGAAACACTCGACAGGCTTGC
CGATGATGGTGTTTACGTCATAGCGAGTGGCCTGAATCTCGACTTCAAGGGAGACCCGTTCCCTGTAACTAGGGAACTTC
TTGTCAGGGCTGACAACATAGTCTACCTAACCGCTGTCTGCACTGTCTGTGGGAGGCCTGCGACCCGAAGTCAGAGGCTT
ATCGATGGAAAGCCTGCTCCCAGGGATTCCCCGGTAATCCTAGTTGGAGGAAGGGAGAGCTACGAGGCTAGATGCAGGCT
CCATCACGAGGTGCCTTAG

Upstream 100 bases:

>100_bases
TGACCGCTCTGACGGCTTTTTCTTCCCATTTTCGTCTTCCGTTCAACTTTTCTTCCGCAGGTAATTTTAACCCCAAGGTT
CTTGGTTCTTCGGTGAGACC

Downstream 100 bases:

>100_bases
CTCGTCAGCACTTTGCTCCAGGTGTTGATGTCTTTGAGTCCGTGGCCGGTTGCGATGATAACTACGCTTTCGCCTTTGTC
TATTATTCCCTCTTCCCTCA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MHPGGFLEVITGPMFAGKTTELIKRIERQMFAKRKAALFKPAIDNRYSEDEIVAHNGLRYEAFVIPTDEEGVRTIGEITK
RENFEVIGIDEVQFFPMSIVETLDRLADDGVYVIASGLNLDFKGDPFPVTRELLVRADNIVYLTAVCTVCGRPATRSQRL
IDGKPAPRDSPVILVGGRESYEARCRLHHEVP

Sequences:

>Translated_192_residues
MHPGGFLEVITGPMFAGKTTELIKRIERQMFAKRKAALFKPAIDNRYSEDEIVAHNGLRYEAFVIPTDEEGVRTIGEITK
RENFEVIGIDEVQFFPMSIVETLDRLADDGVYVIASGLNLDFKGDPFPVTRELLVRADNIVYLTAVCTVCGRPATRSQRL
IDGKPAPRDSPVILVGGRESYEARCRLHHEVP
>Mature_192_residues
MHPGGFLEVITGPMFAGKTTELIKRIERQMFAKRKAALFKPAIDNRYSEDEIVAHNGLRYEAFVIPTDEEGVRTIGEITK
RENFEVIGIDEVQFFPMSIVETLDRLADDGVYVIASGLNLDFKGDPFPVTRELLVRADNIVYLTAVCTVCGRPATRSQRL
IDGKPAPRDSPVILVGGRESYEARCRLHHEVP

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=185, Percent_Identity=36.7567567567568, Blast_Score=98, Evalue=4e-21,
Organism=Escherichia coli, GI1787490, Length=180, Percent_Identity=25.5555555555556, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17543396, Length=185, Percent_Identity=36.2162162162162, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21518; Mature: 21518

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPGGFLEVITGPMFAGKTTELIKRIERQMFAKRKAALFKPAIDNRYSEDEIVAHNGLRY
CCCCCEEHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEE
EAFVIPTDEEGVRTIGEITKRENFEVIGIDEVQFFPMSIVETLDRLADDGVYVIASGLNL
EEEEEECCCHHHHHHHHHHHCCCCEEEECCCCEECHHHHHHHHHHHCCCCEEEEEECCCC
DFKGDPFPVTRELLVRADNIVYLTAVCTVCGRPATRSQRLIDGKPAPRDSPVILVGGRES
CCCCCCCCHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
YEARCRLHHEVP
CEEHEEECCCCC
>Mature Secondary Structure
MHPGGFLEVITGPMFAGKTTELIKRIERQMFAKRKAALFKPAIDNRYSEDEIVAHNGLRY
CCCCCEEHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCEE
EAFVIPTDEEGVRTIGEITKRENFEVIGIDEVQFFPMSIVETLDRLADDGVYVIASGLNL
EEEEEECCCHHHHHHHHHHHCCCCEEEECCCCEECHHHHHHHHHHHCCCCEEEEEECCCC
DFKGDPFPVTRELLVRADNIVYLTAVCTVCGRPATRSQRLIDGKPAPRDSPVILVGGRES
CCCCCCCCHHHHHHHHCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCC
YEARCRLHHEVP
CEEHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA