Click here to switch to the map view.

The map label for this gene is ubiE [C]

Identifier: 212224339

GI number: 212224339

Start: 1086601

End: 1087554

Strand: Reverse

Name: ubiE [C]

Synonym: TON_1190

Alternate gene names: 212224339

Gene position: 1087554-1086601 (Counterclockwise)

Preceding gene: 212224340

Following gene: 212224338

Centisome position: 58.86

GC content: 52.83

Gene sequence:

>954_bases
ATGAATCCCATCGATGCCGTCGATGCCAACATCGAGCAGATGATTAAGTTCTCGGTGCTTGAAATAATCAGCCTTGGAAC
CAAGCATGGTGTGTTTCCACTTCTTGCAAGGGGGCCAACGATTCAGGAGCTGATAGATGAAGTGGATCTTCCCAACAGGC
GCCTTCTACTCGGTTTCATAGAGACCCTCGAGAGCCTGAAGATAGTCAAGGAGAAAAACGGCAGGCTGTACCTCGATGGT
TTCTCATATACCATCAACGTACCAGATGAGAAGTACGACCTTCTCGTCCCGGACTGGGTTCCCATCCAGGAGGAGATCTA
CCGCATGGTGGATTATGCATTCATAACTCCCATTCACCCCCACGTTCTCATGGACTTCGACAAGGACGCTGACTTCTGGG
ACATACGTATGAGCACAAGGTTCTCCCGCATCTACCGCGAGGCGATGGCCCAGGTGGCCGGCCTTAGACAGGGGATGCAT
GTTCTTGACATTGGCTGTGGCTCATATTCCCCGCTCCAGTTCGGGGAGATGATAGGATACAACGGCTTCTACCTCGGCAT
CGACTACTCCCCGGCGCTCATTGAGATAGCTCGCGCCCGTATCGAGGATAAGAGCCTGCCGGTGGAGCTCAAGGAGATGG
ACGCGAAGCTCATAAGGCCTGTGAACGAGTACGACTCTGTTTTCCTCAGTTTCGTCCTTGAGTACATCGATGACTTTCCC
ATGGTACTCAAGCGCGCCATGGAGGCCCTCAATTCTGGTGGTAGGATGGTAATCCTTGAGCCCTTCAGAGACACCTTCAA
GTATGTCCAGGCCCTGGAGTTCTTCGAGGGCCTCAACAAGGACTTCATTGGCTTCCCGTCCGCCCGGGATGTGAAAGATG
CCATCCTGAATGAGGGCTTTGACGTTGAGATAAGCCAGCCAGCGAGGAGCATGCTGGTCGTTAAGAAGATGTAA

Upstream 100 bases:

>100_bases
CGGCTTCAAATACTACCGCCTGACAGACTACGGGAAGAAGGTTGTGGACTACCTCAAGGAATATTACCGCTATTACAGGA
GGTTCATGTGAGGTGATAAC

Downstream 100 bases:

>100_bases
TTCCATAGTCTCTGCTTTTTCACTACTTTGTACCATCCTTAATTAATGTCTTTGTCCCTTGTTGTTTTTGGCACATCTCC
CAGTGAGTTTTGGATGTCCT

Product: SAM-dependent methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNPIDAVDANIEQMIKFSVLEIISLGTKHGVFPLLARGPTIQELIDEVDLPNRRLLLGFIETLESLKIVKEKNGRLYLDG
FSYTINVPDEKYDLLVPDWVPIQEEIYRMVDYAFITPIHPHVLMDFDKDADFWDIRMSTRFSRIYREAMAQVAGLRQGMH
VLDIGCGSYSPLQFGEMIGYNGFYLGIDYSPALIEIARARIEDKSLPVELKEMDAKLIRPVNEYDSVFLSFVLEYIDDFP
MVLKRAMEALNSGGRMVILEPFRDTFKYVQALEFFEGLNKDFIGFPSARDVKDAILNEGFDVEISQPARSMLVVKKM

Sequences:

>Translated_317_residues
MNPIDAVDANIEQMIKFSVLEIISLGTKHGVFPLLARGPTIQELIDEVDLPNRRLLLGFIETLESLKIVKEKNGRLYLDG
FSYTINVPDEKYDLLVPDWVPIQEEIYRMVDYAFITPIHPHVLMDFDKDADFWDIRMSTRFSRIYREAMAQVAGLRQGMH
VLDIGCGSYSPLQFGEMIGYNGFYLGIDYSPALIEIARARIEDKSLPVELKEMDAKLIRPVNEYDSVFLSFVLEYIDDFP
MVLKRAMEALNSGGRMVILEPFRDTFKYVQALEFFEGLNKDFIGFPSARDVKDAILNEGFDVEISQPARSMLVVKKM
>Mature_317_residues
MNPIDAVDANIEQMIKFSVLEIISLGTKHGVFPLLARGPTIQELIDEVDLPNRRLLLGFIETLESLKIVKEKNGRLYLDG
FSYTINVPDEKYDLLVPDWVPIQEEIYRMVDYAFITPIHPHVLMDFDKDADFWDIRMSTRFSRIYREAMAQVAGLRQGMH
VLDIGCGSYSPLQFGEMIGYNGFYLGIDYSPALIEIARARIEDKSLPVELKEMDAKLIRPVNEYDSVFLSFVLEYIDDFP
MVLKRAMEALNSGGRMVILEPFRDTFKYVQALEFFEGLNKDFIGFPSARDVKDAILNEGFDVEISQPARSMLVVKKM

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013217 [H]

Pfam domain/function: PF08242 Methyltransf_12 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 36362; Mature: 36362

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIDAVDANIEQMIKFSVLEIISLGTKHGVFPLLARGPTIQELIDEVDLPNRRLLLGFI
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHCCCCCCHHHHHHH
ETLESLKIVKEKNGRLYLDGFSYTINVPDEKYDLLVPDWVPIQEEIYRMVDYAFITPIHP
HHHHHHHHHHHCCCEEEEECEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCC
HVLMDFDKDADFWDIRMSTRFSRIYREAMAQVAGLRQGMHVLDIGCGSYSPLQFGEMIGY
CEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCC
NGFYLGIDYSPALIEIARARIEDKSLPVELKEMDAKLIRPVNEYDSVFLSFVLEYIDDFP
CCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
MVLKRAMEALNSGGRMVILEPFRDTFKYVQALEFFEGLNKDFIGFPSARDVKDAILNEGF
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCC
DVEISQPARSMLVVKKM
CEEECCCHHHEEEEECC
>Mature Secondary Structure
MNPIDAVDANIEQMIKFSVLEIISLGTKHGVFPLLARGPTIQELIDEVDLPNRRLLLGFI
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHHHHHHCCCCCCHHHHHHH
ETLESLKIVKEKNGRLYLDGFSYTINVPDEKYDLLVPDWVPIQEEIYRMVDYAFITPIHP
HHHHHHHHHHHCCCEEEEECEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCC
HVLMDFDKDADFWDIRMSTRFSRIYREAMAQVAGLRQGMHVLDIGCGSYSPLQFGEMIGY
CEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHCC
NGFYLGIDYSPALIEIARARIEDKSLPVELKEMDAKLIRPVNEYDSVFLSFVLEYIDDFP
CCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
MVLKRAMEALNSGGRMVILEPFRDTFKYVQALEFFEGLNKDFIGFPSARDVKDAILNEGF
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCC
DVEISQPARSMLVVKKM
CEEECCCHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]