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The map label for this gene is dbpA [C]

Identifier: 212224218

GI number: 212224218

Start: 984126

End: 986495

Strand: Reverse

Name: dbpA [C]

Synonym: TON_1069

Alternate gene names: 212224218

Gene position: 986495-984126 (Counterclockwise)

Preceding gene: 212224220

Following gene: 212224215

Centisome position: 53.39

GC content: 53.71

Gene sequence:

>2370_bases
ATGTATCTCCGCAGGGACTTAATCCAGCCGCGCGTTTACCAGGAGGTCATCTACGCGAGGTGTAAGGAGAGTAACTGCCT
TGTTGTTCTGCCAACCGGATTAGGAAAGACTCTCATCGCGATGCTTATCGCCGACTACAGGCTTCAAAAATACGGCGGTA
AAGTTTTAATGCTCGCCCCTACAAAGCCCCTGGCTTTACAGCACGCGGAGAGCTTCAAAAAGCTCTTTGACATTCCTCCG
GAGAAAATAAACGTCCTGACAGGGGAGCTCTCGCCTAAAACAAGGCAGGAAATCTGGGAGAAAAGCGTGATAATAACTGC
CACGCCTCAAACGATAGAGAATGACATTTTAACAGGCAGGATCTCCCTTGAGGACGTCGTACTTCTCGTCTTCGACGAGG
CCCACAGGGCGGTGGGCAACTACTCCTACGTCTTCATCGCAAGGGAGTACCTCAAGACTGCTAAACATCCGCTTGTTCTT
GGCCTTACGGCCTCCCCTGGAAGCGACGAGGTGAGGATAAGGGAAATAATCAATAACCTCGGAATAGAGCGCATCGAGAT
AAGAACCGAGAGCTCACCGGATGTGAAGCCCTACGTCCATAGGATAGCCTTTGAGTGGGTCAAGGTCGACCTTCCAGGCG
TCTACAAGGAGGTCCGCTCCCTCCTGAGGGGGATGCTCAAGGAGAGCCTCAAACCCCTCGCCCAGTTTAAGCTCGTGAGT
TCATACTCGCCAGATATCTCAAAGAAGGAAGTTCTCCAGGCGGGCTCAAAAATCAATCAGGAGGTCGCGAGGGGCAACTA
CGAGATTGGGAGGCTGAGGATGTACCAGGCTAAAGCAGTCAAGCTCCAGCACGCGATTGAGCTCCTTGAGACGCAGGGAC
TGACCGCCCTCCGTGCTTATCTCAAAAAGCTTCGCGAGGACAAACGGACGAAGTCAAGCAGAGAGCTGATGGAAGATCCT
CGTATGAGAAAAGTGATATATCTCTTAGTCCAGGCGAAGGAGCTTGGAATAGACCACCCCAAGATGGAGAAGCTCAAGGA
GCTCGTTAAGGCCCAGCTGGAGAAAAAGCCGAACTCCAAGATAATCGTCTTTACCAACTACCGCGACACAGGAAAGAAGA
TAGTTGAGGAGCTTCGAGCGATGAGTGTCAGTGCGGAGCGCTTCATTGGTCAGGCCAGCAGGAGCAACGACCGGGGCATG
AGTCAGAAACAGCAGAAAGAGACGTTAGAGCGCTTTTCTAGGGGTGAGTTCAGCGTTCTGGTCGCCACAAGCGTCGGTGA
GGAAGGTCTCGATGTCCCCGAAGTCGACCTGGTAATCTTCTACGAGCCCGTGCCTTCCGCCATCAGAAGCATCCAGAGAC
GTGGACGGACTGGAAGGCACAGGCCGGGTAGGGTCGTTATCCTCATGGCGAAGGGAACGCGCGACGAGGCCTACTACTGG
AGCTCCAGACGGAAGGAAAGGGGAATGTTTGAGGCGATTAGGAAGATAGCCCGTGAGCTTGAGGCCGAGATGAAGGAGAG
GGAGGATATGAAGAGGGGTAAGATCACTTCCCTCGATGCTTTTCTAAAGCCCAAGAAGAAGCCGGCTGAAGAAAAAGCCG
AAGGAATTGAAGAGGCTGAGAAGCCCTCTGAGGGGAAAGTGGAAAAATACGAAAAGGCCGAGCCCTCGAAAGAGGAGCTC
TACGAGAAGCTCCCGATAAAGCCCGTCTTTGTCAGAAGGCCAAAGGGCATAGTTGTTTACGTTGACAGCAGGGAGCTAAG
AAGCGGCGTGCCAAAGCATCTCAGGGGGCTCGGGGCCGAGGTCGAGGTAAAGACGCTTGACGTTGCTGACTATGTGGTGA
GCGAAGAGGTCGGAATAGAGCGCAAGAGCGCCAACGACTTCATACAGTCCATAATCGATGGAAGGCTCTTTGACCAGGTG
GAGAGGTTGAAGAAGGCCTATGAGAAGCCCGTGATAATTATCGAGGGGCAACTCTACGGTATAAGGAACGTTCACCCCAA
CGCGATTAGGGGTGCCATAGCGGCTGTCACTTTGGACTGGGGCGTGCCGATACTCTTCTCCTCTGGGCCGGAAGAGACTG
CCCAGTTCATCTACCTGATGGCCAAGCGCGAGCAGGAGGAGAGGAAGAAGGAGGTAAGACTGAGGAGCGAGAAGAAGGCC
CTAACTCTTGCCGAAAGGCAGCGGTTGATAGTCGAGGGACTGCCCAACGTCTCGGCCACTCTGGCAAAGAGGCTCCTCAA
GCACTTCGGCAACGTCGAGAGGGTTTTCACCGCCACGGAGGAGGAGCTTCAGGAAGTTGAAGGCATCGGCCCGAAGAAGG
CGAGGGAGATAAGGAAGGTGATAACGGCACCTTATGTGGAAGAGGAGTGA

Upstream 100 bases:

>100_bases
TTTAGCGAGTCTTTTGACGAGTCTCTCCTTGGCGTGTCTCGTGAGTAGCATGACCTCAGTTCGTCCGAGAATTTATAAAC
TTCGTCGAGGAGATAGGAGT

Downstream 100 bases:

>100_bases
GGCTTGGAAAGCACTGAGTCCATTCCATTCACTCTTACGGTAATCTTGGGGATGTCTCCCATGCTCCGGAGCTTTCCGTC
GGTCAGAAAGGCCAGTACGA

Product: Hef nuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 789

Protein sequence:

>789_residues
MYLRRDLIQPRVYQEVIYARCKESNCLVVLPTGLGKTLIAMLIADYRLQKYGGKVLMLAPTKPLALQHAESFKKLFDIPP
EKINVLTGELSPKTRQEIWEKSVIITATPQTIENDILTGRISLEDVVLLVFDEAHRAVGNYSYVFIAREYLKTAKHPLVL
GLTASPGSDEVRIREIINNLGIERIEIRTESSPDVKPYVHRIAFEWVKVDLPGVYKEVRSLLRGMLKESLKPLAQFKLVS
SYSPDISKKEVLQAGSKINQEVARGNYEIGRLRMYQAKAVKLQHAIELLETQGLTALRAYLKKLREDKRTKSSRELMEDP
RMRKVIYLLVQAKELGIDHPKMEKLKELVKAQLEKKPNSKIIVFTNYRDTGKKIVEELRAMSVSAERFIGQASRSNDRGM
SQKQQKETLERFSRGEFSVLVATSVGEEGLDVPEVDLVIFYEPVPSAIRSIQRRGRTGRHRPGRVVILMAKGTRDEAYYW
SSRRKERGMFEAIRKIARELEAEMKEREDMKRGKITSLDAFLKPKKKPAEEKAEGIEEAEKPSEGKVEKYEKAEPSKEEL
YEKLPIKPVFVRRPKGIVVYVDSRELRSGVPKHLRGLGAEVEVKTLDVADYVVSEEVGIERKSANDFIQSIIDGRLFDQV
ERLKKAYEKPVIIIEGQLYGIRNVHPNAIRGAIAAVTLDWGVPILFSSGPEETAQFIYLMAKREQEERKKEVRLRSEKKA
LTLAERQRLIVEGLPNVSATLAKRLLKHFGNVERVFTATEEELQEVEGIGPKKAREIRKVITAPYVEEE

Sequences:

>Translated_789_residues
MYLRRDLIQPRVYQEVIYARCKESNCLVVLPTGLGKTLIAMLIADYRLQKYGGKVLMLAPTKPLALQHAESFKKLFDIPP
EKINVLTGELSPKTRQEIWEKSVIITATPQTIENDILTGRISLEDVVLLVFDEAHRAVGNYSYVFIAREYLKTAKHPLVL
GLTASPGSDEVRIREIINNLGIERIEIRTESSPDVKPYVHRIAFEWVKVDLPGVYKEVRSLLRGMLKESLKPLAQFKLVS
SYSPDISKKEVLQAGSKINQEVARGNYEIGRLRMYQAKAVKLQHAIELLETQGLTALRAYLKKLREDKRTKSSRELMEDP
RMRKVIYLLVQAKELGIDHPKMEKLKELVKAQLEKKPNSKIIVFTNYRDTGKKIVEELRAMSVSAERFIGQASRSNDRGM
SQKQQKETLERFSRGEFSVLVATSVGEEGLDVPEVDLVIFYEPVPSAIRSIQRRGRTGRHRPGRVVILMAKGTRDEAYYW
SSRRKERGMFEAIRKIARELEAEMKEREDMKRGKITSLDAFLKPKKKPAEEKAEGIEEAEKPSEGKVEKYEKAEPSKEEL
YEKLPIKPVFVRRPKGIVVYVDSRELRSGVPKHLRGLGAEVEVKTLDVADYVVSEEVGIERKSANDFIQSIIDGRLFDQV
ERLKKAYEKPVIIIEGQLYGIRNVHPNAIRGAIAAVTLDWGVPILFSSGPEETAQFIYLMAKREQEERKKEVRLRSEKKA
LTLAERQRLIVEGLPNVSATLAKRLLKHFGNVERVFTATEEELQEVEGIGPKKAREIRKVITAPYVEEE
>Mature_789_residues
MYLRRDLIQPRVYQEVIYARCKESNCLVVLPTGLGKTLIAMLIADYRLQKYGGKVLMLAPTKPLALQHAESFKKLFDIPP
EKINVLTGELSPKTRQEIWEKSVIITATPQTIENDILTGRISLEDVVLLVFDEAHRAVGNYSYVFIAREYLKTAKHPLVL
GLTASPGSDEVRIREIINNLGIERIEIRTESSPDVKPYVHRIAFEWVKVDLPGVYKEVRSLLRGMLKESLKPLAQFKLVS
SYSPDISKKEVLQAGSKINQEVARGNYEIGRLRMYQAKAVKLQHAIELLETQGLTALRAYLKKLREDKRTKSSRELMEDP
RMRKVIYLLVQAKELGIDHPKMEKLKELVKAQLEKKPNSKIIVFTNYRDTGKKIVEELRAMSVSAERFIGQASRSNDRGM
SQKQQKETLERFSRGEFSVLVATSVGEEGLDVPEVDLVIFYEPVPSAIRSIQRRGRTGRHRPGRVVILMAKGTRDEAYYW
SSRRKERGMFEAIRKIARELEAEMKEREDMKRGKITSLDAFLKPKKKPAEEKAEGIEEAEKPSEGKVEKYEKAEPSKEEL
YEKLPIKPVFVRRPKGIVVYVDSRELRSGVPKHLRGLGAEVEVKTLDVADYVVSEEVGIERKSANDFIQSIIDGRLFDQV
ERLKKAYEKPVIIIEGQLYGIRNVHPNAIRGAIAAVTLDWGVPILFSSGPEETAQFIYLMAKREQEERKKEVRLRSEKKA
LTLAERQRLIVEGLPNVSATLAKRLLKHFGNVERVFTATEEELQEVEGIGPKKAREIRKVITAPYVEEE

Specific function: Has A Helix-Destabilizing Activity, Which Is Not Coupled To The Atpase Activity. Can Unwind The 23s Rrna As Well As 16s Rrna. Exhibits An RNA-Dependent Atpase Activity, Specifically Stimulated By Bacterial 23s Rrna. Could Play A Major Role In Ribosome Ass

COG id: COG1111

COG function: function code L; ERCC4-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI74959747, Length=532, Percent_Identity=32.1428571428571, Blast_Score=262, Evalue=1e-69,
Organism=Homo sapiens, GI27881482, Length=532, Percent_Identity=25.3759398496241, Blast_Score=117, Evalue=5e-26,
Organism=Homo sapiens, GI149408122, Length=559, Percent_Identity=24.1502683363148, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4885217, Length=371, Percent_Identity=23.989218328841, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI27886568, Length=166, Percent_Identity=28.9156626506024, Blast_Score=72, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982860, Length=176, Percent_Identity=32.3863636363636, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539846, Length=187, Percent_Identity=33.6898395721925, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17532461, Length=281, Percent_Identity=24.9110320284698, Blast_Score=76, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6322192, Length=574, Percent_Identity=27.8745644599303, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI116008407, Length=501, Percent_Identity=30.3393213572854, Blast_Score=221, Evalue=2e-57,
Organism=Drosophila melanogaster, GI17933560, Length=224, Percent_Identity=27.2321428571429, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR020819
- InterPro:   IPR006166
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR011335
- InterPro:   IPR010994 [H]

Pfam domain/function: PF00270 DEAD; PF02732 ERCC4; PF00271 Helicase_C; PF00633 HHH [H]

EC number: =3.6.4.13 [H]

Molecular weight: Translated: 90107; Mature: 90107

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLRRDLIQPRVYQEVIYARCKESNCLVVLPTGLGKTLIAMLIADYRLQKYGGKVLMLAP
CCCHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEC
TKPLALQHAESFKKLFDIPPEKINVLTGELSPKTRQEIWEKSVIITATPQTIENDILTGR
CCCHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHCCEEEEECCCHHHCCCEEEE
ISLEDVVLLVFDEAHRAVGNYSYVFIAREYLKTAKHPLVLGLTASPGSDEVRIREIINNL
EEHHHEEEEEEHHHHHHHCCCEEEEEEHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHC
GIERIEIRTESSPDVKPYVHRIAFEWVKVDLPGVYKEVRSLLRGMLKESLKPLAQFKLVS
CCEEEEEECCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYSPDISKKEVLQAGSKINQEVARGNYEIGRLRMYQAKAVKLQHAIELLETQGLTALRAY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHHHCCHHHHHHH
LKKLREDKRTKSSRELMEDPRMRKVIYLLVQAKELGIDHPKMEKLKELVKAQLEKKPNSK
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCE
IIVFTNYRDTGKKIVEELRAMSVSAERFIGQASRSNDRGMSQKQQKETLERFSRGEFSVL
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEE
VATSVGEEGLDVPEVDLVIFYEPVPSAIRSIQRRGRTGRHRPGRVVILMAKGTRDEAYYW
EEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHH
SSRRKERGMFEAIRKIARELEAEMKEREDMKRGKITSLDAFLKPKKKPAEEKAEGIEEAE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHC
KPSEGKVEKYEKAEPSKEELYEKLPIKPVFVRRPKGIVVYVDSRELRSGVPKHLRGLGAE
CCCCCCCHHHHCCCCCHHHHHHHCCCCEEEEECCCCEEEEECCHHHHCCCCHHHHCCCCE
VEVKTLDVADYVVSEEVGIERKSANDFIQSIIDGRLFDQVERLKKAYEKPVIIIEGQLYG
EEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCEEE
IRNVHPNAIRGAIAAVTLDWGVPILFSSGPEETAQFIYLMAKREQEERKKEVRLRSEKKA
ECCCCCHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLAERQRLIVEGLPNVSATLAKRLLKHFGNVERVFTATEEELQEVEGIGPKKAREIRKV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
ITAPYVEEE
HHCCCCCCC
>Mature Secondary Structure
MYLRRDLIQPRVYQEVIYARCKESNCLVVLPTGLGKTLIAMLIADYRLQKYGGKVLMLAP
CCCHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEC
TKPLALQHAESFKKLFDIPPEKINVLTGELSPKTRQEIWEKSVIITATPQTIENDILTGR
CCCHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHCCEEEEECCCHHHCCCEEEE
ISLEDVVLLVFDEAHRAVGNYSYVFIAREYLKTAKHPLVLGLTASPGSDEVRIREIINNL
EEHHHEEEEEEHHHHHHHCCCEEEEEEHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHC
GIERIEIRTESSPDVKPYVHRIAFEWVKVDLPGVYKEVRSLLRGMLKESLKPLAQFKLVS
CCEEEEEECCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYSPDISKKEVLQAGSKINQEVARGNYEIGRLRMYQAKAVKLQHAIELLETQGLTALRAY
CCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHHHCCHHHHHHH
LKKLREDKRTKSSRELMEDPRMRKVIYLLVQAKELGIDHPKMEKLKELVKAQLEKKPNSK
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCE
IIVFTNYRDTGKKIVEELRAMSVSAERFIGQASRSNDRGMSQKQQKETLERFSRGEFSVL
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEE
VATSVGEEGLDVPEVDLVIFYEPVPSAIRSIQRRGRTGRHRPGRVVILMAKGTRDEAYYW
EEECCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHH
SSRRKERGMFEAIRKIARELEAEMKEREDMKRGKITSLDAFLKPKKKPAEEKAEGIEEAE
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHC
KPSEGKVEKYEKAEPSKEELYEKLPIKPVFVRRPKGIVVYVDSRELRSGVPKHLRGLGAE
CCCCCCCHHHHCCCCCHHHHHHHCCCCEEEEECCCCEEEEECCHHHHCCCCHHHHCCCCE
VEVKTLDVADYVVSEEVGIERKSANDFIQSIIDGRLFDQVERLKKAYEKPVIIIEGQLYG
EEEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCEEE
IRNVHPNAIRGAIAAVTLDWGVPILFSSGPEETAQFIYLMAKREQEERKKEVRLRSEKKA
ECCCCCHHHHHHHHEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLAERQRLIVEGLPNVSATLAKRLLKHFGNVERVFTATEEELQEVEGIGPKKAREIRKV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHH
ITAPYVEEE
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]