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The map label for this gene is xerC [C]

Identifier: 212224162

GI number: 212224162

Start: 935913

End: 936761

Strand: Reverse

Name: xerC [C]

Synonym: TON_1013

Alternate gene names: 212224162

Gene position: 936761-935913 (Counterclockwise)

Preceding gene: 212224163

Following gene: 212224159

Centisome position: 50.7

GC content: 53.36

Gene sequence:

>849_bases
ATGGAAGCCATCAACGAGGTAATCGAGGAGTACGAGACTTACCTTGATCTGGAGGGCAAGAGCCCGAACACCATTAGGAT
GTACTCCTACTACGTGAGGCGTTATCTGGAAGGGGGCGGGGAGCTTAAAGCCCGCTCCGCACTCCGTTTTCTCGCAAAGC
TCAGGCGCGAAGGTTACTCCAACAAGAGTCTGAACCTTGTCGTCCAAGCCCTGCGCTCCTACTTCCGCTTTGAAGGCTAT
GATGAAGAGGCCGAAAAGCTCAGGCCGCCAAAGGTACCCAAGAGCCTCCCCAAGAGCCTGACGAGGGAGGAGGTCAGGAA
AATTCTCTCCGTTATCCCGCCGACGAAGAAGCGCGACAGGCTCATTTTTCTCCTCCTCTACGGCGCAGGTCTTCGCGTCA
GCGAGCTGTGCAATCTGAAGAAGTCCGATGTCGACTTCGAGCGCTCCCTTATAATCGTTCGCGGCGGAAAGGGCGCCAAG
GATCGCGTTGTGCCGATTCCTGCCTTCCTGCTGGAAGGGATTAAGGCTTACCTTGAAACAAGAGATGACGACAGCGAATA
CCTTATTGTGGAAGACAGGCGGGAGAGGAAGGATAAGCTCTCTCCGAAGACCGTCTGGTACCTCCTTAAAAAATACGGCG
ACAGGGCTGGAATTCGGGTTACACCCCATATGCTCCGCCACAGCTTTGCCACCCACATGCTCGAAAACGGCGTTGATATA
AGGGCTATTCAGGAACTGCTCGGTCACTCGAACCTGTCAACAACTCAGATTTACACGAAAGTCACAGTGGAGCATCTCAG
GAAGGCACAGGAGAAGGCGAGGTTGATAGAGGGATTAATTGAGAAATAA

Upstream 100 bases:

>100_bases
GAGCCGCCAAAACCGTCTGAGCCTCCCGAAGAGCCAGAAGTTGTCGCTGACGCAGAGATAAAGCCTGACGACATTGAGGG
CCTCTTGAAGGGGCTGTGAA

Downstream 100 bases:

>100_bases
TCAGAGTTCTCCTTTCTCTTTCAGCAGGGCAAGGTAGCTCGTGAAGGCTCCAGCTGAAATCGTGTCTCCGAGGCCAACCG
TTGAAACCGGGTTCTTGACT

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MEAINEVIEEYETYLDLEGKSPNTIRMYSYYVRRYLEGGGELKARSALRFLAKLRREGYSNKSLNLVVQALRSYFRFEGY
DEEAEKLRPPKVPKSLPKSLTREEVRKILSVIPPTKKRDRLIFLLLYGAGLRVSELCNLKKSDVDFERSLIIVRGGKGAK
DRVVPIPAFLLEGIKAYLETRDDDSEYLIVEDRRERKDKLSPKTVWYLLKKYGDRAGIRVTPHMLRHSFATHMLENGVDI
RAIQELLGHSNLSTTQIYTKVTVEHLRKAQEKARLIEGLIEK

Sequences:

>Translated_282_residues
MEAINEVIEEYETYLDLEGKSPNTIRMYSYYVRRYLEGGGELKARSALRFLAKLRREGYSNKSLNLVVQALRSYFRFEGY
DEEAEKLRPPKVPKSLPKSLTREEVRKILSVIPPTKKRDRLIFLLLYGAGLRVSELCNLKKSDVDFERSLIIVRGGKGAK
DRVVPIPAFLLEGIKAYLETRDDDSEYLIVEDRRERKDKLSPKTVWYLLKKYGDRAGIRVTPHMLRHSFATHMLENGVDI
RAIQELLGHSNLSTTQIYTKVTVEHLRKAQEKARLIEGLIEK
>Mature_282_residues
MEAINEVIEEYETYLDLEGKSPNTIRMYSYYVRRYLEGGGELKARSALRFLAKLRREGYSNKSLNLVVQALRSYFRFEGY
DEEAEKLRPPKVPKSLPKSLTREEVRKILSVIPPTKKRDRLIFLLLYGAGLRVSELCNLKKSDVDFERSLIIVRGGKGAK
DRVVPIPAFLLEGIKAYLETRDDDSEYLIVEDRRERKDKLSPKTVWYLLKKYGDRAGIRVTPHMLRHSFATHMLENGVDI
RAIQELLGHSNLSTTQIYTKVTVEHLRKAQEKARLIEGLIEK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=34.4594594594595, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789261, Length=249, Percent_Identity=37.3493975903614, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1790767, Length=183, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790768, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERCL_THEON (B6YWN8)

Other databases:

- EMBL:   CP000855
- RefSeq:   YP_002307398.1
- GeneID:   7018032
- GenomeReviews:   CP000855_GR
- KEGG:   ton:TON_1013
- HOGENOM:   HBG727654
- OMA:   YLHASRE
- ProtClustDB:   CLSK340523
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz

EC number: NA

Molecular weight: Translated: 32689; Mature: 32689

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: ACT_SITE 132-132 ACT_SITE 157-157 ACT_SITE 223-223 ACT_SITE 226-226 ACT_SITE 249-249 ACT_SITE 258-258

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAINEVIEEYETYLDLEGKSPNTIRMYSYYVRRYLEGGGELKARSALRFLAKLRREGYS
CHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
NKSLNLVVQALRSYFRFEGYDEEAEKLRPPKVPKSLPKSLTREEVRKILSVIPPTKKRDR
CCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
LIFLLLYGAGLRVSELCNLKKSDVDFERSLIIVRGGKGAKDRVVPIPAFLLEGIKAYLET
EEEEEEECCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
RDDDSEYLIVEDRRERKDKLSPKTVWYLLKKYGDRAGIRVTPHMLRHSFATHMLENGVDI
CCCCCCEEEECCHHHHHHCCCHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCH
RAIQELLGHSNLSTTQIYTKVTVEHLRKAQEKARLIEGLIEK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEAINEVIEEYETYLDLEGKSPNTIRMYSYYVRRYLEGGGELKARSALRFLAKLRREGYS
CHHHHHHHHHHHHHEECCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
NKSLNLVVQALRSYFRFEGYDEEAEKLRPPKVPKSLPKSLTREEVRKILSVIPPTKKRDR
CCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
LIFLLLYGAGLRVSELCNLKKSDVDFERSLIIVRGGKGAKDRVVPIPAFLLEGIKAYLET
EEEEEEECCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
RDDDSEYLIVEDRRERKDKLSPKTVWYLLKKYGDRAGIRVTPHMLRHSFATHMLENGVDI
CCCCCCEEEECCHHHHHHCCCHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCH
RAIQELLGHSNLSTTQIYTKVTVEHLRKAQEKARLIEGLIEK
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA