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The map label for this gene is 212224092

Identifier: 212224092

GI number: 212224092

Start: 868088

End: 869668

Strand: Reverse

Name: 212224092

Synonym: TON_0943

Alternate gene names: NA

Gene position: 869668-868088 (Counterclockwise)

Preceding gene: 212224094

Following gene: 212224087

Centisome position: 47.07

GC content: 55.72

Gene sequence:

>1581_bases
ATGAGCCCTCCCGAGCGAATCCTCCTCGTCACCGGCAAGCTCGCCGAACCGCTTGTTCGAAAGTACGGTAAGGGCTGCGA
CGTTTTCGTTACGCCCCTGAGCGTAGCGGCTTTTCTGACTCCCGAGATGATAGTTCGCTATCTGAAGAAGGCTAAAATCA
AAAGCGAGGAGTACGACCTTATTCTCATTCCTGGCCTCGTGAGGGGCTCGACCCAAGAAATCGAGGAAGAGCTGGGCATT
CCCACATTCAAGGGGCCGAGGAACGCGATGGACCTTCCTCAGGTGCTGAAGGCGGTAAGAGAAGGCTTCAATCTGAGCAA
AGAGGTTCCGGCGGATGACCTCTTCTCCTTCGATGCTCTAAAGCGCGTTGAGGACATAAGGAACCGGACGAGAAACAAGC
GCTACATGGAGGAGGCCCTCAAAAGGCCGTGGAACGTCCTTGTAGGGAACCTGCCCGCGGGGAGGGACTTTCCCACCAGA
ATCCTCGGCGAGGTCGTCGATGCCCCGAGGCTGGGCGTCGAAGGAACCGTGCAAAAGGCCCTCTACTACCTCCGTGAGGG
GGCGGATATAATTGATATCGGTATGATCGCGGGCGAGACGAACCTTGACTTCGTCGAGCTCATCCCCGAAATACGCGAGA
GGCTGAGGGAGAACGGTTTCGACGTGCCCATAAGCTTTGACTCTCTAAACACCGCTGAAATCGAAAGGGCCCTTGATTAC
GCTGATCTGTTCCTCAGCGTCGATGATAGCAACCTGGAGAGCCTTGTTACCGATAAGCCCGTCGTTCTCATCCCAACCAA
CCAGGCGAAAGGGTATTTTCCAACGAGACCTGCGAAGAGAGTTGAATTTCTTGAGGGGCTTAAGGCCAGGGCCCTTGATC
TGGGTTACAAAACGATAATCTCGGACCTAATCCTGGAGCACGTGCCCCATCTGGCGCGCTCGATAACGGCCTTCCAGCTC
TACCGTGAGAGGAACCCGGACGACGTTCTCCTTGCCGGCGTCGGAAACGTCGTCGAGCTCTACGACGCCGACAGCGTCGG
GATGAACGCCCTTCTTGCTGGAATGGCCAAGGAGCTCTCTATAGGCCTTCTCCTAACGACGGAGACAAGCGCCAAGGCCA
GGGGCTCGATAAGGGAGCTGCGGAGAGCCCTGGACATGAACCTCTTTGAGATGCCAAAGGACCTCGGCTTTGACCTGCTG
ATACTCAAAGAGAAGAGGACCAATGACTGGCGCTTTGAGCCTGCCAAAGAAATCGTCAAGGCCGAGGAGAGGCCAGTTGA
GCTCGAACCCGTTTACTTCCGCATCTGGCTTGAAGATGGGAAAATATGGGTGAACGCTCACCACGGAACAAAGGCCGTCT
TAACCATCGTCGGAGACGAGCCGAACGCGATAATCGACACAATCCTTGAGTGCTTTGAGATAAGCCCGAGGCACGCCTTT
TACCTCGGCAGGGAGCTGGAGAAGGCCTACACCGCGCTGAGACTGAGGAGAAGCTATGTCCAGGAGGTCGAGCTTTTTAA
GGACTTCTACCTTCAGAACAAGGGAAGTGATGAGCGGAGCTCTCCTGAGGGCTCCCGATGA

Upstream 100 bases:

>100_bases
TAACATCGCCGGAGAGAATTTGTCCTGGGAGCATTTAACCCTTTCGTGAAGGCAAAGTTTGTACGAAAGCTCTAAATAGC
GGGAACGCCAATCTCCGACC

Downstream 100 bases:

>100_bases
TGACTACAGCCAGGGCTGATCCTTAGCCCTCGAAAATCGGTGGCTTCGCCTTCCTGAACTGCTCGTCAAGCTCTGCTCTC
CTTGCACTGACCCTTTCCAG

Product: Pterin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MSPPERILLVTGKLAEPLVRKYGKGCDVFVTPLSVAAFLTPEMIVRYLKKAKIKSEEYDLILIPGLVRGSTQEIEEELGI
PTFKGPRNAMDLPQVLKAVREGFNLSKEVPADDLFSFDALKRVEDIRNRTRNKRYMEEALKRPWNVLVGNLPAGRDFPTR
ILGEVVDAPRLGVEGTVQKALYYLREGADIIDIGMIAGETNLDFVELIPEIRERLRENGFDVPISFDSLNTAEIERALDY
ADLFLSVDDSNLESLVTDKPVVLIPTNQAKGYFPTRPAKRVEFLEGLKARALDLGYKTIISDLILEHVPHLARSITAFQL
YRERNPDDVLLAGVGNVVELYDADSVGMNALLAGMAKELSIGLLLTTETSAKARGSIRELRRALDMNLFEMPKDLGFDLL
ILKEKRTNDWRFEPAKEIVKAEERPVELEPVYFRIWLEDGKIWVNAHHGTKAVLTIVGDEPNAIIDTILECFEISPRHAF
YLGRELEKAYTALRLRRSYVQEVELFKDFYLQNKGSDERSSPEGSR

Sequences:

>Translated_526_residues
MSPPERILLVTGKLAEPLVRKYGKGCDVFVTPLSVAAFLTPEMIVRYLKKAKIKSEEYDLILIPGLVRGSTQEIEEELGI
PTFKGPRNAMDLPQVLKAVREGFNLSKEVPADDLFSFDALKRVEDIRNRTRNKRYMEEALKRPWNVLVGNLPAGRDFPTR
ILGEVVDAPRLGVEGTVQKALYYLREGADIIDIGMIAGETNLDFVELIPEIRERLRENGFDVPISFDSLNTAEIERALDY
ADLFLSVDDSNLESLVTDKPVVLIPTNQAKGYFPTRPAKRVEFLEGLKARALDLGYKTIISDLILEHVPHLARSITAFQL
YRERNPDDVLLAGVGNVVELYDADSVGMNALLAGMAKELSIGLLLTTETSAKARGSIRELRRALDMNLFEMPKDLGFDLL
ILKEKRTNDWRFEPAKEIVKAEERPVELEPVYFRIWLEDGKIWVNAHHGTKAVLTIVGDEPNAIIDTILECFEISPRHAF
YLGRELEKAYTALRLRRSYVQEVELFKDFYLQNKGSDERSSPEGSR
>Mature_525_residues
SPPERILLVTGKLAEPLVRKYGKGCDVFVTPLSVAAFLTPEMIVRYLKKAKIKSEEYDLILIPGLVRGSTQEIEEELGIP
TFKGPRNAMDLPQVLKAVREGFNLSKEVPADDLFSFDALKRVEDIRNRTRNKRYMEEALKRPWNVLVGNLPAGRDFPTRI
LGEVVDAPRLGVEGTVQKALYYLREGADIIDIGMIAGETNLDFVELIPEIRERLRENGFDVPISFDSLNTAEIERALDYA
DLFLSVDDSNLESLVTDKPVVLIPTNQAKGYFPTRPAKRVEFLEGLKARALDLGYKTIISDLILEHVPHLARSITAFQLY
RERNPDDVLLAGVGNVVELYDADSVGMNALLAGMAKELSIGLLLTTETSAKARGSIRELRRALDMNLFEMPKDLGFDLLI
LKEKRTNDWRFEPAKEIVKAEERPVELEPVYFRIWLEDGKIWVNAHHGTKAVLTIVGDEPNAIIDTILECFEISPRHAFY
LGRELEKAYTALRLRRSYVQEVELFKDFYLQNKGSDERSSPEGSR

Specific function: Unknown. Does not possess dihydropteroate synthase (DHPS) activity since it does not catalyze the condensation of 6- hydroxymethyl-7,8-dihydropterin pyrophosphate (DHPP) and 4- aminobenzoate to form 7,8-dihydropteroate [H]

COG id: COG0294

COG function: function code H; Dihydropteroate synthase and related enzymes

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005236
- InterPro:   IPR011005
- InterPro:   IPR000489 [H]

Pfam domain/function: PF00809 Pterin_bind [H]

EC number: NA

Molecular weight: Translated: 59507; Mature: 59376

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPERILLVTGKLAEPLVRKYGKGCDVFVTPLSVAAFLTPEMIVRYLKKAKIKSEEYDL
CCCCCEEEEEECHHHHHHHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCE
ILIPGLVRGSTQEIEEELGIPTFKGPRNAMDLPQVLKAVREGFNLSKEVPADDLFSFDAL
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KRVEDIRNRTRNKRYMEEALKRPWNVLVGNLPAGRDFPTRILGEVVDAPRLGVEGTVQKA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
LYYLREGADIIDIGMIAGETNLDFVELIPEIRERLRENGFDVPISFDSLNTAEIERALDY
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
ADLFLSVDDSNLESLVTDKPVVLIPTNQAKGYFPTRPAKRVEFLEGLKARALDLGYKTII
HHHEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SDLILEHVPHLARSITAFQLYRERNPDDVLLAGVGNVVELYDADSVGMNALLAGMAKELS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHE
IGLLLTTETSAKARGSIRELRRALDMNLFEMPKDLGFDLLILKEKRTNDWRFEPAKEIVK
EEEEEEECCCHHHHHHHHHHHHHHCCCHHHCCHHCCCEEEEEEECCCCCCCCCHHHHHHH
AEERPVELEPVYFRIWLEDGKIWVNAHHGTKAVLTIVGDEPNAIIDTILECFEISPRHAF
HCCCCCEECCEEEEEEEECCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHH
YLGRELEKAYTALRLRRSYVQEVELFKDFYLQNKGSDERSSPEGSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPPERILLVTGKLAEPLVRKYGKGCDVFVTPLSVAAFLTPEMIVRYLKKAKIKSEEYDL
CCCCEEEEEECHHHHHHHHHHCCCCEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCCCE
ILIPGLVRGSTQEIEEELGIPTFKGPRNAMDLPQVLKAVREGFNLSKEVPADDLFSFDAL
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KRVEDIRNRTRNKRYMEEALKRPWNVLVGNLPAGRDFPTRILGEVVDAPRLGVEGTVQKA
HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
LYYLREGADIIDIGMIAGETNLDFVELIPEIRERLRENGFDVPISFDSLNTAEIERALDY
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHH
ADLFLSVDDSNLESLVTDKPVVLIPTNQAKGYFPTRPAKRVEFLEGLKARALDLGYKTII
HHHEEEECCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SDLILEHVPHLARSITAFQLYRERNPDDVLLAGVGNVVELYDADSVGMNALLAGMAKELS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHHE
IGLLLTTETSAKARGSIRELRRALDMNLFEMPKDLGFDLLILKEKRTNDWRFEPAKEIVK
EEEEEEECCCHHHHHHHHHHHHHHCCCHHHCCHHCCCEEEEEEECCCCCCCCCHHHHHHH
AEERPVELEPVYFRIWLEDGKIWVNAHHGTKAVLTIVGDEPNAIIDTILECFEISPRHAF
HCCCCCEECCEEEEEEEECCEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCHHH
YLGRELEKAYTALRLRRSYVQEVELFKDFYLQNKGSDERSSPEGSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]