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The map label for this gene is 212223783

Identifier: 212223783

GI number: 212223783

Start: 591326

End: 591841

Strand: Reverse

Name: 212223783

Synonym: TON_0635

Alternate gene names: NA

Gene position: 591841-591326 (Counterclockwise)

Preceding gene: 212223785

Following gene: 212223776

Centisome position: 32.03

GC content: 51.55

Gene sequence:

>516_bases
ATGCCAATAACGACCAAAACCGGTGATAAGGGTTTAACAGGCCTCTTTACAGGCGACAGAATTGCGAAGTACTCACCCAT
AATGGAAGCTAACGGCACCATAGACGAGCTGAGCAGCTTTCTGGGCGAGGCCAAACACTACGTGCCCAAAGAGATGGCAG
AGGTACTAGAAAAAATCCAGGTCGAGCTTTACTCGCTCATGGCTGAGATAGCCAGTAAGGGCAAGTACAAAAAGGTCGGG
GAAGGGGAAGTCAAGTGGCTTGAGGAACTTATTCATAAGTATGAAGAAGAAGTCCAGCTCCGCGCCTTCGTCCTGCCGGG
CTCCACCATCGCCAGCGCCAAGCTCGATGTGTGCAGGACAGTTGCAAGGAGGGCCGAGAGGGCCGTTGCACGGCTCGTTC
TTGATTACGGCTTTGGAAGCAGCGCCCTCATCTACCTTAATAGGCTCAGCGACCTGTTATTCATAATGGCACGGGCAATA
GAAAAGAGGGAGGGAAAGATAAAAGAGGTCAAGTAG

Upstream 100 bases:

>100_bases
AAGTTTTTCCATAACTTACTCCGACAATTTATCACTCACCGTGTTCAGAAATTCCGAAATTAATAAAACTTGGTCACACA
ATACCCACCTCGGTGATCCC

Downstream 100 bases:

>100_bases
CTCTCTCCGCTTCAGCTCTCTCCGTATTTTTGCTCCCTGAGTAGGGTCTCCCTGTGCTCGATGTAGTAGTAGAGTATCAC
GGCCCCCATCATAATCCAAA

Product: cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; ORFW [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPITTKTGDKGLTGLFTGDRIAKYSPIMEANGTIDELSSFLGEAKHYVPKEMAEVLEKIQVELYSLMAEIASKGKYKKVG
EGEVKWLEELIHKYEEEVQLRAFVLPGSTIASAKLDVCRTVARRAERAVARLVLDYGFGSSALIYLNRLSDLLFIMARAI
EKREGKIKEVK

Sequences:

>Translated_171_residues
MPITTKTGDKGLTGLFTGDRIAKYSPIMEANGTIDELSSFLGEAKHYVPKEMAEVLEKIQVELYSLMAEIASKGKYKKVG
EGEVKWLEELIHKYEEEVQLRAFVLPGSTIASAKLDVCRTVARRAERAVARLVLDYGFGSSALIYLNRLSDLLFIMARAI
EKREGKIKEVK
>Mature_170_residues
PITTKTGDKGLTGLFTGDRIAKYSPIMEANGTIDELSSFLGEAKHYVPKEMAEVLEKIQVELYSLMAEIASKGKYKKVGE
GEVKWLEELIHKYEEEVQLRAFVLPGSTIASAKLDVCRTVARRAERAVARLVLDYGFGSSALIYLNRLSDLLFIMARAIE
KREGKIKEVK

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=180, Percent_Identity=39.4444444444444, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI115534154, Length=166, Percent_Identity=34.3373493975904, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19130; Mature: 18998

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITTKTGDKGLTGLFTGDRIAKYSPIMEANGTIDELSSFLGEAKHYVPKEMAEVLEKIQ
CCCCCCCCCCCCEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
VELYSLMAEIASKGKYKKVGEGEVKWLEELIHKYEEEVQLRAFVLPGSTIASAKLDVCRT
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
VARRAERAVARLVLDYGFGSSALIYLNRLSDLLFIMARAIEKREGKIKEVK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PITTKTGDKGLTGLFTGDRIAKYSPIMEANGTIDELSSFLGEAKHYVPKEMAEVLEKIQ
CCCCCCCCCCCEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
VELYSLMAEIASKGKYKKVGEGEVKWLEELIHKYEEEVQLRAFVLPGSTIASAKLDVCRT
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHH
VARRAERAVARLVLDYGFGSSALIYLNRLSDLLFIMARAIEKREGKIKEVK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA