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The map label for this gene is 212223503

Identifier: 212223503

GI number: 212223503

Start: 331582

End: 332388

Strand: Reverse

Name: 212223503

Synonym: TON_0357

Alternate gene names: NA

Gene position: 332388-331582 (Counterclockwise)

Preceding gene: 212223507

Following gene: 212223502

Centisome position: 17.99

GC content: 52.79

Gene sequence:

>807_bases
ATGAAACTGACGGTTCTCTACGAAAATAACTCGGGTTTTAAAAAGGGTCCCCTCGGGGCTCATGGCTTCTCTGCCCTGGT
GGAACACCGGGGAGTTAGGGTTCTCGTTGATACTGGAACGGACGGGAGGATCCTTCTCAACAACATGGAGGAGTTCAGAG
TAAAACCAAGAAAAATCAATTACATATTCATCACCCACGGTCACTACGACCACACGGGCGGGCTTAAAGTGTTCCTCGAA
GCGAGGGGAAAACCTATCAAGGTGATAGCTCATCCGGAGATATTCCGGAGAAGAATAGCACTTAAGCCACACAGGCGCGA
TATAGGGATTCCGTTCACGAGGGAAGAGCTTGAAGCTCTTGGAGCCGAGTTTATTTTAAGCGAGAAGCCCCTCGAGTTCG
CGCCCGGCTTCATCAGCTCCGGCGAAATCGAGAGAAGAACCTGGGACAGGGCGGTAGGCTATCTCGAAGAGAAAGGGGAG
CTCATCAAAGACCCCGTTAGGGACGACATGGCTCTCATAGTCGACCTGGGAGAGAGCGCTGCAGTTATCACCGGTTGCGG
ACACTCAGGCGTTCTCAACATAGCCTGGCAAGCCGAAGACGTTTTGGGGAAGCCCGTTAAAGCCCTAATCGGAGGGCTGC
ATCTCCTCGGTGCGAGCAAAGAGCTCCTTGATGACGTAGTTGAGAAAATTGACGCCGAAAAGCTCTACGCAGGCCACTGC
ACGGGCATAGACTCCTACGCCTATCTGAAGGCGAGACTTGGGGATAGAATAGAGCACCTTCACGTGGGCAAAACGGTAGA
GCTCTAG

Upstream 100 bases:

>100_bases
TACCCGAAATCAAGGGGAGAGAGTAGTCATTCAAATATACCATGGTGACCACATGAAAGGTTTTAACTCTATGGGAACAT
AAACTTTTCGAGGGAGTGAT

Downstream 100 bases:

>100_bases
CGAACCTTTAAATACCCAGTCGAAAAGCTAACCACCGCGAGAGAAAAGGGGAGGTGAGAGAGATGAAGAACCCATTCGAG
AAGATGCCAACTGTCCTTAC

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKLTVLYENNSGFKKGPLGAHGFSALVEHRGVRVLVDTGTDGRILLNNMEEFRVKPRKINYIFITHGHYDHTGGLKVFLE
ARGKPIKVIAHPEIFRRRIALKPHRRDIGIPFTREELEALGAEFILSEKPLEFAPGFISSGEIERRTWDRAVGYLEEKGE
LIKDPVRDDMALIVDLGESAAVITGCGHSGVLNIAWQAEDVLGKPVKALIGGLHLLGASKELLDDVVEKIDAEKLYAGHC
TGIDSYAYLKARLGDRIEHLHVGKTVEL

Sequences:

>Translated_268_residues
MKLTVLYENNSGFKKGPLGAHGFSALVEHRGVRVLVDTGTDGRILLNNMEEFRVKPRKINYIFITHGHYDHTGGLKVFLE
ARGKPIKVIAHPEIFRRRIALKPHRRDIGIPFTREELEALGAEFILSEKPLEFAPGFISSGEIERRTWDRAVGYLEEKGE
LIKDPVRDDMALIVDLGESAAVITGCGHSGVLNIAWQAEDVLGKPVKALIGGLHLLGASKELLDDVVEKIDAEKLYAGHC
TGIDSYAYLKARLGDRIEHLHVGKTVEL
>Mature_268_residues
MKLTVLYENNSGFKKGPLGAHGFSALVEHRGVRVLVDTGTDGRILLNNMEEFRVKPRKINYIFITHGHYDHTGGLKVFLE
ARGKPIKVIAHPEIFRRRIALKPHRRDIGIPFTREELEALGAEFILSEKPLEFAPGFISSGEIERRTWDRAVGYLEEKGE
LIKDPVRDDMALIVDLGESAAVITGCGHSGVLNIAWQAEDVLGKPVKALIGGLHLLGASKELLDDVVEKIDAEKLYAGHC
TGIDSYAYLKARLGDRIEHLHVGKTVEL

Specific function: Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin- 6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor

COG id: COG1237

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 29745; Mature: 29745

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTVLYENNSGFKKGPLGAHGFSALVEHRGVRVLVDTGTDGRILLNNMEEFRVKPRKIN
CEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEECCCHHHCCCCEEEE
YIFITHGHYDHTGGLKVFLEARGKPIKVIAHPEIFRRRIALKPHRRDIGIPFTREELEAL
EEEEECCCCCCCCCEEEEEECCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHC
GAEFILSEKPLEFAPGFISSGEIERRTWDRAVGYLEEKGELIKDPVRDDMALIVDLGESA
CHHHEECCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCE
AVITGCGHSGVLNIAWQAEDVLGKPVKALIGGLHLLGASKELLDDVVEKIDAEKLYAGHC
EEEEECCCCCEEEEEEECHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHEEECCC
TGIDSYAYLKARLGDRIEHLHVGKTVEL
CCCCHHHHHHHHHCCHHHEEECCCEECC
>Mature Secondary Structure
MKLTVLYENNSGFKKGPLGAHGFSALVEHRGVRVLVDTGTDGRILLNNMEEFRVKPRKIN
CEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCEEEECCCHHHCCCCEEEE
YIFITHGHYDHTGGLKVFLEARGKPIKVIAHPEIFRRRIALKPHRRDIGIPFTREELEAL
EEEEECCCCCCCCCEEEEEECCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCHHHHHHC
GAEFILSEKPLEFAPGFISSGEIERRTWDRAVGYLEEKGELIKDPVRDDMALIVDLGESA
CHHHEECCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEEECCCCE
AVITGCGHSGVLNIAWQAEDVLGKPVKALIGGLHLLGASKELLDDVVEKIDAEKLYAGHC
EEEEECCCCCEEEEEEECHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHEEECCC
TGIDSYAYLKARLGDRIEHLHVGKTVEL
CCCCHHHHHHHHHCCHHHEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]