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The map label for this gene is prsW [H]

Identifier: 212223354

GI number: 212223354

Start: 185131

End: 185838

Strand: Reverse

Name: prsW [H]

Synonym: TON_0208

Alternate gene names: 212223354

Gene position: 185838-185131 (Counterclockwise)

Preceding gene: 212223355

Following gene: 212223353

Centisome position: 10.06

GC content: 54.8

Gene sequence:

>708_bases
ATGGACGTGTTGAGTGCACTTGTGTTCTTCGCCTACGCTCCTGCGCTTGTCATACTCTGGTACTTCTATCACGCGGACAA
GTTCGAGCCAGAGCCCAAAAAATACGTCATAGGCACATTCATCCTCGGCGGAACGCTCTCCGTTGGAATAGCGTACATTC
TGGAGATGTTTCTTACTATTGGCGGCAGGGTGGATCCGGTACTCCCAACGACTGCCTTCTATGTGGCTCTCGTCGCAGGT
ATCGTGGAAGAGCCAGCCAAGGCCTTGGCGATTAGGTGGCCGTTCAAGGCAGGCCAGATGGACGGCATAATGGACGGCCT
TGTTTACGGAGTCGCCGCTGGCCTCGGCTTTGCCGCCACGGAGAACTTCCTGTATGGCCTCGGTTACGGCATTCCGGTCA
CGATTGTGAGAGGATTCTTAACGCCCTTTGCCCACGCCACGTGGAGCGCAATAATTGGCGTTGGCTACGGCATGAAGGCC
GAAGGAAAAGTGGACTCGGTGGGCCCGTTCTTCCTGCTGGCCATCATCCTGCACTTCGTCTGGGACTACTACGCCTTCCT
AAGCTACAACGTGGCGGCATACCACATAATGTTGATTCTGTTCATTATGATCAACTTGGCGATACTGCGCTACTTCCTCC
TGATGGGCCAAGCGGAGGATGCCAGTAGGGTATGGTACTACTGGTTCAGGAGGGGTGGGTATGAGTGA

Upstream 100 bases:

>100_bases
CCCATACCCTACTCCAACTAGGAAGCTCTTGTAGGAGGCCCTTGCCAGATGCTAAACCTTTAAATTTCCAGCTTTCCATT
CTTTTTTGGTGAGCAGCAAT

Downstream 100 bases:

>100_bases
CAAGCTTAACGAGGCCCTCTTTGAGGCGAGGCCTTACGTGGAGTACTATGAAAAGCTAGAAAACCTTGTAAAAAGGCTCT
GGACGGAGGCAGCGACCGAG

Product: membrane protein, conserved

Products: NA

Alternate protein names: Protease responsible for activating sigma-W [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MDVLSALVFFAYAPALVILWYFYHADKFEPEPKKYVIGTFILGGTLSVGIAYILEMFLTIGGRVDPVLPTTAFYVALVAG
IVEEPAKALAIRWPFKAGQMDGIMDGLVYGVAAGLGFAATENFLYGLGYGIPVTIVRGFLTPFAHATWSAIIGVGYGMKA
EGKVDSVGPFFLLAIILHFVWDYYAFLSYNVAAYHIMLILFIMINLAILRYFLLMGQAEDASRVWYYWFRRGGYE

Sequences:

>Translated_235_residues
MDVLSALVFFAYAPALVILWYFYHADKFEPEPKKYVIGTFILGGTLSVGIAYILEMFLTIGGRVDPVLPTTAFYVALVAG
IVEEPAKALAIRWPFKAGQMDGIMDGLVYGVAAGLGFAATENFLYGLGYGIPVTIVRGFLTPFAHATWSAIIGVGYGMKA
EGKVDSVGPFFLLAIILHFVWDYYAFLSYNVAAYHIMLILFIMINLAILRYFLLMGQAEDASRVWYYWFRRGGYE
>Mature_235_residues
MDVLSALVFFAYAPALVILWYFYHADKFEPEPKKYVIGTFILGGTLSVGIAYILEMFLTIGGRVDPVLPTTAFYVALVAG
IVEEPAKALAIRWPFKAGQMDGIMDGLVYGVAAGLGFAATENFLYGLGYGIPVTIVRGFLTPFAHATWSAIIGVGYGMKA
EGKVDSVGPFFLLAIILHFVWDYYAFLSYNVAAYHIMLILFIMINLAILRYFLLMGQAEDASRVWYYWFRRGGYE

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26147; Mature: 26147

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLSALVFFAYAPALVILWYFYHADKFEPEPKKYVIGTFILGGTLSVGIAYILEMFLTI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
GGRVDPVLPTTAFYVALVAGIVEEPAKALAIRWPFKAGQMDGIMDGLVYGVAAGLGFAAT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHH
ENFLYGLGYGIPVTIVRGFLTPFAHATWSAIIGVGYGMKAEGKVDSVGPFFLLAIILHFV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
WDYYAFLSYNVAAYHIMLILFIMINLAILRYFLLMGQAEDASRVWYYWFRRGGYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDVLSALVFFAYAPALVILWYFYHADKFEPEPKKYVIGTFILGGTLSVGIAYILEMFLTI
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
GGRVDPVLPTTAFYVALVAGIVEEPAKALAIRWPFKAGQMDGIMDGLVYGVAAGLGFAAT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHH
ENFLYGLGYGIPVTIVRGFLTPFAHATWSAIIGVGYGMKAEGKVDSVGPFFLLAIILHFV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
WDYYAFLSYNVAAYHIMLILFIMINLAILRYFLLMGQAEDASRVWYYWFRRGGYE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA