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The map label for this gene is 212223302

Identifier: 212223302

GI number: 212223302

Start: 131567

End: 133150

Strand: Reverse

Name: 212223302

Synonym: TON_0156

Alternate gene names: NA

Gene position: 133150-131567 (Counterclockwise)

Preceding gene: 212223304

Following gene: 212223301

Centisome position: 7.21

GC content: 53.41

Gene sequence:

>1584_bases
GTGGAACAGAGGGATCAGTGGGCAACCAAGATTGGTTTAATTTTAGCCATGGCCGGAAATGCCATAGGTCTTGGAAACTT
CTGGAGGTTCCCATACCAGCTCGCTAGCAACGGTGGCGGCGCATTCATGATACCGTACTTCATAGCGTTGGTGTTCCTGG
GAATCCCTGTGATGTGGATTGAGTGGACCACCGGTCGCTACGGTGGTAAATACGGACACGGTACAATCGGACCAATGTTC
TACCTCATGGCCAGGGAGAGCCTCAAGCCAAGGACAGCCATGATCTTCGGTATCATCGGTGGAATGCTGGCCTTCTCGGT
CGCTTCCCTGCTCAGCTCATACTACTATCAGGTCATAGGCTGGTCCGCGGCTTACACCTACTACAGCCTAACCGGAGCCT
ACTTCGGCAAGGATACAGTGCAGTTCTTCCTTGACTATGTCGCCAACACCAAGGCAGTGATATTCTTCTGGGGACTGACG
ATGCTCTTCCTTGGAATAGCAGTTGGGCAGGGAGTTAGCAAAGGTATCGAGCGCTGGGTTAAAGTCATGATGCCCCTCCT
GTACGTGTTCGCTGTACTCCTGGTTCTCAGGGCACTGACCCTTGGCTCACCCGTAAAGCCAGAGTGGAGCGCCATCAAGG
GTCTCGAGTACATCTGGAAGCCTGACTTTCAGACACTCAGCCAGAACTTCTTCAGGATAAGCCTGGCAGCGGCGGGACAG
ATATTCTTCACACTGTCCCTCGGTATGGGTATCATACACAACTACGCAAGCTACCTCGGTCCTGAGGACGACGTTGCCCT
CTCAGGTCTCGCCACAGTTTCACTCAACGAGTTCGCAGAGGTCATCCTCGGTGGTTCTCTCGCCATCCCGATAGCCTTCG
CCTACCTCGGTCCAGAGCAGGCCGTCAAGGGTGGTGTCGGTCTCGCATACATGGCCCTTCCGAACGTCTTCGCCAACATG
CCGGCAGGTCAGATATTCGGTGCCATGTGGTTCCTCCTGCTCTGGTTCGCGGGATTCACTTCAGCTATAGCCACCTACAA
CTACCTCGTCGCCATGCTCGAGGAGGACATTCACATTGAGAGGAAGGTTGGCACCTGGCTAGTGTTCATATTCCTGTTCC
TGCTTGGACTGCCAGTTGCCCTTGACAGCACCCTAGCGTACCTCAGCGAGCTCGACATGTGGGTTGGTTCCTACTTCCTC
GTGCTGCTTGGTCTCTTCGACATCATAGTTGCAGTTTGGCTCTTCAAGCCCGACAACTTCTGGGAGGAGCTCCACAAGGG
TGCTTACATTAAAGTTCCAGAGTGGTACAGGCCAATAATGACCATAATAGCGCCGCTGTTCATGCTGTTCCTCCTCGGTG
GCAACACCCTTGACTACATCAAGAAAGGAGCCTTCAGCGTCTCAGAGGCCTACGTCACTCAGGTTCTCGGCTACGACTAC
ACCCCAGAAATCATCAGCCTCATCATTAGGGCTAGGATAGTTATCATCATAATCCTCGTCATCGGTGCTATCGAGGCTTA
CCTGGCCATCAAGAAGAAGTACGGCGAAGAGCTCGCAAAGAACGAGGTGCTCATAAAACTCTGA

Upstream 100 bases:

>100_bases
ATTAGAAAGCTTTTTATAGAATGCAAGAGCCCATACATAATGCCCCGTTATAGTACACGGGGTTTCGTTACCCACGCATT
TAAGAACGGGGGTGAATAAT

Downstream 100 bases:

>100_bases
GGTGATGAAAATGGACACAGGCGCTCTGGTATTCCTAATATTTGCGTGGGGTTCAATATTTACCCTGATGTACTGGAGCA
TTACAAAGCTACTTCGTGCC

Product: sodium-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MEQRDQWATKIGLILAMAGNAIGLGNFWRFPYQLASNGGGAFMIPYFIALVFLGIPVMWIEWTTGRYGGKYGHGTIGPMF
YLMARESLKPRTAMIFGIIGGMLAFSVASLLSSYYYQVIGWSAAYTYYSLTGAYFGKDTVQFFLDYVANTKAVIFFWGLT
MLFLGIAVGQGVSKGIERWVKVMMPLLYVFAVLLVLRALTLGSPVKPEWSAIKGLEYIWKPDFQTLSQNFFRISLAAAGQ
IFFTLSLGMGIIHNYASYLGPEDDVALSGLATVSLNEFAEVILGGSLAIPIAFAYLGPEQAVKGGVGLAYMALPNVFANM
PAGQIFGAMWFLLLWFAGFTSAIATYNYLVAMLEEDIHIERKVGTWLVFIFLFLLGLPVALDSTLAYLSELDMWVGSYFL
VLLGLFDIIVAVWLFKPDNFWEELHKGAYIKVPEWYRPIMTIIAPLFMLFLLGGNTLDYIKKGAFSVSEAYVTQVLGYDY
TPEIISLIIRARIVIIIILVIGAIEAYLAIKKKYGEELAKNEVLIKL

Sequences:

>Translated_527_residues
MEQRDQWATKIGLILAMAGNAIGLGNFWRFPYQLASNGGGAFMIPYFIALVFLGIPVMWIEWTTGRYGGKYGHGTIGPMF
YLMARESLKPRTAMIFGIIGGMLAFSVASLLSSYYYQVIGWSAAYTYYSLTGAYFGKDTVQFFLDYVANTKAVIFFWGLT
MLFLGIAVGQGVSKGIERWVKVMMPLLYVFAVLLVLRALTLGSPVKPEWSAIKGLEYIWKPDFQTLSQNFFRISLAAAGQ
IFFTLSLGMGIIHNYASYLGPEDDVALSGLATVSLNEFAEVILGGSLAIPIAFAYLGPEQAVKGGVGLAYMALPNVFANM
PAGQIFGAMWFLLLWFAGFTSAIATYNYLVAMLEEDIHIERKVGTWLVFIFLFLLGLPVALDSTLAYLSELDMWVGSYFL
VLLGLFDIIVAVWLFKPDNFWEELHKGAYIKVPEWYRPIMTIIAPLFMLFLLGGNTLDYIKKGAFSVSEAYVTQVLGYDY
TPEIISLIIRARIVIIIILVIGAIEAYLAIKKKYGEELAKNEVLIKL
>Mature_527_residues
MEQRDQWATKIGLILAMAGNAIGLGNFWRFPYQLASNGGGAFMIPYFIALVFLGIPVMWIEWTTGRYGGKYGHGTIGPMF
YLMARESLKPRTAMIFGIIGGMLAFSVASLLSSYYYQVIGWSAAYTYYSLTGAYFGKDTVQFFLDYVANTKAVIFFWGLT
MLFLGIAVGQGVSKGIERWVKVMMPLLYVFAVLLVLRALTLGSPVKPEWSAIKGLEYIWKPDFQTLSQNFFRISLAAAGQ
IFFTLSLGMGIIHNYASYLGPEDDVALSGLATVSLNEFAEVILGGSLAIPIAFAYLGPEQAVKGGVGLAYMALPNVFANM
PAGQIFGAMWFLLLWFAGFTSAIATYNYLVAMLEEDIHIERKVGTWLVFIFLFLLGLPVALDSTLAYLSELDMWVGSYFL
VLLGLFDIIVAVWLFKPDNFWEELHKGAYIKVPEWYRPIMTIIAPLFMLFLLGGNTLDYIKKGAFSVSEAYVTQVLGYDY
TPEIISLIIRARIVIIIILVIGAIEAYLAIKKKYGEELAKNEVLIKL

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=500, Percent_Identity=23.6, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI4507043, Length=530, Percent_Identity=25.2830188679245, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI171184408, Length=491, Percent_Identity=24.847250509165, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI171184406, Length=491, Percent_Identity=24.847250509165, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI171184404, Length=491, Percent_Identity=24.847250509165, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI21361581, Length=484, Percent_Identity=25, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI7657587, Length=512, Percent_Identity=23.6328125, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4507041, Length=501, Percent_Identity=22.9540918163673, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI197276623, Length=568, Percent_Identity=23.0633802816901, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI54607094, Length=568, Percent_Identity=23.0633802816901, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI289191377, Length=499, Percent_Identity=23.8476953907816, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI289191351, Length=499, Percent_Identity=23.8476953907816, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4557046, Length=499, Percent_Identity=23.8476953907816, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI194018524, Length=311, Percent_Identity=28.2958199356913, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI92859670, Length=506, Percent_Identity=22.7272727272727, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI134304856, Length=502, Percent_Identity=22.9083665338645, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI58219014, Length=332, Percent_Identity=28.0120481927711, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI33354281, Length=329, Percent_Identity=26.1398176291793, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI51468073, Length=314, Percent_Identity=26.1146496815287, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI67782317, Length=517, Percent_Identity=23.4042553191489, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI67782313, Length=517, Percent_Identity=23.4042553191489, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI67782315, Length=517, Percent_Identity=23.4042553191489, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI11181770, Length=607, Percent_Identity=21.2520593080725, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI197276625, Length=128, Percent_Identity=38.28125, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI5032097, Length=493, Percent_Identity=21.501014198783, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI218563756, Length=498, Percent_Identity=22.289156626506, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI21361693, Length=124, Percent_Identity=36.2903225806452, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI12408638, Length=583, Percent_Identity=20.2401372212693, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI6005715, Length=67, Percent_Identity=47.7611940298507, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146584, Length=497, Percent_Identity=23.5412474849095, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71995588, Length=464, Percent_Identity=23.9224137931034, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133952791, Length=131, Percent_Identity=39.6946564885496, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17554804, Length=502, Percent_Identity=24.7011952191235, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=122, Percent_Identity=36.8852459016393, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555248, Length=80, Percent_Identity=42.5, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=124, Percent_Identity=33.8709677419355, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17136952, Length=503, Percent_Identity=22.0675944333996, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281364394, Length=502, Percent_Identity=22.3107569721116, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574704, Length=502, Percent_Identity=22.3107569721116, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136950, Length=502, Percent_Identity=22.3107569721116, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574702, Length=502, Percent_Identity=22.3107569721116, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652942, Length=491, Percent_Identity=25.050916496945, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45551088, Length=491, Percent_Identity=25.050916496945, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19921936, Length=496, Percent_Identity=23.7903225806452, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24661428, Length=496, Percent_Identity=22.9838709677419, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24762620, Length=496, Percent_Identity=22.9838709677419, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24582567, Length=463, Percent_Identity=23.5421166306695, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281363702, Length=486, Percent_Identity=25.5144032921811, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI281364136, Length=498, Percent_Identity=23.4939759036145, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24655079, Length=534, Percent_Identity=21.9101123595506, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24639514, Length=487, Percent_Identity=23.2032854209446, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221329674, Length=487, Percent_Identity=23.2032854209446, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24639853, Length=537, Percent_Identity=22.3463687150838, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24639516, Length=510, Percent_Identity=23.3333333333333, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363700, Length=348, Percent_Identity=28.1609195402299, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654186, Length=290, Percent_Identity=24.8275862068966, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551183, Length=132, Percent_Identity=34.8484848484849, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45550877, Length=132, Percent_Identity=34.8484848484849, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281365034, Length=279, Percent_Identity=26.5232974910394, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921352, Length=279, Percent_Identity=26.5232974910394, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584353, Length=279, Percent_Identity=26.5232974910394, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 58652; Mature: 58652

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]