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The map label for this gene is udp [H]

Identifier: 212223277

GI number: 212223277

Start: 103106

End: 103939

Strand: Reverse

Name: udp [H]

Synonym: TON_0131

Alternate gene names: 212223277

Gene position: 103939-103106 (Counterclockwise)

Preceding gene: 212223286

Following gene: 212223276

Centisome position: 5.63

GC content: 54.92

Gene sequence:

>834_bases
ATGACAAAGTTCCTATCTGCAGACAGGCCCCAAACTGAGGAAGGCTATCAGTACCACATAGCATGCAAGCCGGGGGATGT
TTCAAGATATGTTCTCCTGCCCGGCGACCCAGAGAGGGTTCCAAAGATAAGCTCTCTGTGGGATGAGGCAAAGGAGATAG
CCTTCCACAGGGAATACAGAACTCACACGGGCAAATACAAGGGGGTTCCAATAAGCGTTACTTCAACCGGGATAGGTGGG
CCCTCAACGGCGATAGCGATTGAAGAGCTCGCAGCCATTGGAGCAGATACCTTCATAAGAGTAGGCTCCACCGGCGCTAT
CCAGCGTGGAATGGAAATAGGCGACCTCATCATAGCGAAGGCAGCGGTTAGGCTCGAGGGCACTTCAAAGCAGTACGTGA
GGATTGAATATCCAGCCGTTGCCGACTTGGAGGTTACCCTCGCACTAATCGAGGCCGCCGAGACCCTCGGAGTGCGCTAT
CATATCGGCATAACCGCCTCGACCGACAGCTTCTACCTCGGCCAAGGAAGGCCAGGCTTAAACGGTTACTTCCCGAGCTT
CGCCAAGAACATCCTCGACGACCTCAGGCAGGCCAGGGTCACCAACTTTGAGATGGAAGCGGCGACCCTCTTCACGCTGG
CGAACATCTACGGCCTCAGGGCTGGCTGTGTCTGTGCAGTCTTTGCTAACAGGGTAACCAACGAGTTCGGCAAAGCTGGA
GAGAAGGAAGCCGCAATGGTCGCCACTGAGGCCGTAAAGATACTCGCCGAATGGGACGAAGAGAAGGAGCAGAAAGGCAA
GAAGGTGTGGTTCCCGGGATTGAGAAGGCTTTAG

Upstream 100 bases:

>100_bases
CAAAGAGGCTTCTGCTCCATATTTTATAGACTTTTAGTTAGGGAAGACTTTTTATCCACAATTCTACAAGGTATTCTCAC
AAAAGCGATGGGTGATTGCC

Downstream 100 bases:

>100_bases
CTGTTCTGTTTGACCTTTAATTTTCTGTGGAATTAACCTGCGTCACACGGAATTCTTTGAATTTTTGCCCAATTTTCACA
ATTTCATGAAGCATCCAAAA

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTKFLSADRPQTEEGYQYHIACKPGDVSRYVLLPGDPERVPKISSLWDEAKEIAFHREYRTHTGKYKGVPISVTSTGIGG
PSTAIAIEELAAIGADTFIRVGSTGAIQRGMEIGDLIIAKAAVRLEGTSKQYVRIEYPAVADLEVTLALIEAAETLGVRY
HIGITASTDSFYLGQGRPGLNGYFPSFAKNILDDLRQARVTNFEMEAATLFTLANIYGLRAGCVCAVFANRVTNEFGKAG
EKEAAMVATEAVKILAEWDEEKEQKGKKVWFPGLRRL

Sequences:

>Translated_277_residues
MTKFLSADRPQTEEGYQYHIACKPGDVSRYVLLPGDPERVPKISSLWDEAKEIAFHREYRTHTGKYKGVPISVTSTGIGG
PSTAIAIEELAAIGADTFIRVGSTGAIQRGMEIGDLIIAKAAVRLEGTSKQYVRIEYPAVADLEVTLALIEAAETLGVRY
HIGITASTDSFYLGQGRPGLNGYFPSFAKNILDDLRQARVTNFEMEAATLFTLANIYGLRAGCVCAVFANRVTNEFGKAG
EKEAAMVATEAVKILAEWDEEKEQKGKKVWFPGLRRL
>Mature_276_residues
TKFLSADRPQTEEGYQYHIACKPGDVSRYVLLPGDPERVPKISSLWDEAKEIAFHREYRTHTGKYKGVPISVTSTGIGGP
STAIAIEELAAIGADTFIRVGSTGAIQRGMEIGDLIIAKAAVRLEGTSKQYVRIEYPAVADLEVTLALIEAAETLGVRYH
IGITASTDSFYLGQGRPGLNGYFPSFAKNILDDLRQARVTNFEMEAATLFTLANIYGLRAGCVCAVFANRVTNEFGKAGE
KEAAMVATEAVKILAEWDEEKEQKGKKVWFPGLRRL

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=243, Percent_Identity=43.2098765432099, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1790844, Length=242, Percent_Identity=29.7520661157025, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 30313; Mature: 30182

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFLSADRPQTEEGYQYHIACKPGDVSRYVLLPGDPERVPKISSLWDEAKEIAFHREYR
CCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHH
THTGKYKGVPISVTSTGIGGPSTAIAIEELAAIGADTFIRVGSTGAIQRGMEIGDLIIAK
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHHHHHH
AAVRLEGTSKQYVRIEYPAVADLEVTLALIEAAETLGVRYHIGITASTDSFYLGQGRPGL
HHEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCEEECCCCCCC
NGYFPSFAKNILDDLRQARVTNFEMEAATLFTLANIYGLRAGCVCAVFANRVTNEFGKAG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EKEAAMVATEAVKILAEWDEEKEQKGKKVWFPGLRRL
CCHHHHHHHHHHHHHHHCCHHHHHCCCEEECCHHCCC
>Mature Secondary Structure 
TKFLSADRPQTEEGYQYHIACKPGDVSRYVLLPGDPERVPKISSLWDEAKEIAFHREYR
CCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHH
THTGKYKGVPISVTSTGIGGPSTAIAIEELAAIGADTFIRVGSTGAIQRGMEIGDLIIAK
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHHHHHH
AAVRLEGTSKQYVRIEYPAVADLEVTLALIEAAETLGVRYHIGITASTDSFYLGQGRPGL
HHEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCCEEECCCCCCC
NGYFPSFAKNILDDLRQARVTNFEMEAATLFTLANIYGLRAGCVCAVFANRVTNEFGKAG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EKEAAMVATEAVKILAEWDEEKEQKGKKVWFPGLRRL
CCHHHHHHHHHHHHHHHCCHHHHHCCCEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]