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The map label for this gene is lspL [H]

Identifier: 209696419

GI number: 209696419

Start: 3279138

End: 3280274

Strand: Direct

Name: lspL [H]

Synonym: VSAL_I3029

Alternate gene names: 209696419

Gene position: 3279138-3280274 (Clockwise)

Preceding gene: 209696418

Following gene: 209696420

Centisome position: 98.62

GC content: 34.48

Gene sequence:

>1137_bases
ATGACTAAGAATGTATTAATCACAGGTGGTGCAGGCTTTATTGGCTCAAATTTGGCGCTGGATTTAATAGATAAAGGCTG
TAATGTCACAGTACTTGATAATTTATCACCGCAGATACATGGAGAAAATCCTGAATTATCACCTTTGTATTGTTCAATAA
AAGGTAAAGTTCGATTTATTCAAGGTACTGTGGAATCTCGTGACGACTGGCTAGAAGCATTGAAAGATATTGATACTGTT
GTTCATTTAGCGGCAGAGACCGGAACTGGACAGTCGATGTACCAAATAAAAAAATATTCAGATATCAATATTGGTGGTAG
CGCGATATTTTTAGATTTACTTGCTAATGAACCACATAACATCACTAAGATGGTAATTGCCTCTTCACGATCTATTTACG
GGGAAGGTAAGTATTTATGTTCAGAACACGGCATTGTGTATCCTAACGCCCGCAATGATGAAGATATGAAGCATGATGAT
TTTAATGTTAAGTGCCCTTTATGCTCCATTAATGTTGAATTGCTTGCTACTGATGAAGAAAGCAAAATACATCCTTCTTC
TATTTATGGTGTAACGAAACAAGTTCAAGAACAAATGTTTATGATCACAGGGGAAAGTTTAGATATTCCTACCGTGTCAT
TAAGATTTCAAAATGTATATGGCGCTGGTCAGTCATTATCTAATCCATACACAGGTATCTTATCTATTTTTTCAACGAGA
ATTAAAAATGGTAATGATATCAATATATTTGAAGATGGTTTGGAAAGTCGTGATTTTGTTTATATCGATGATGTAGTCGA
TTCTATTGTACTCTCTATTTTCAATGAGAATGCAAATTATCAAATCTTTAATGTTGGTTCTGGGGTCTGTACAGACGTAT
TGAGCGTTGCAGAGACATTGAAGAGTGTTTATGAGTCTAGTTCTAATATACTGATTAGTAGCAATTATCGTGTTGGAGAT
ATTCGACATAATTTTGCCGATCTTACTTTAATTAAATCGAAAATCGGATTTGAACCTAAAGTTGATTTTGTTAGTGGTAT
GCGAAAATTTACTGCTTGGGTTAATCAACAAGAAGTTCAAGCTGACTTGTATGAAAGCTCCATTGCTGAAATGAAGTCAA
AAGGCTTGTATAAATAA

Upstream 100 bases:

>100_bases
TATAGTCGGTGTCCCAGCAAAAATTATTAAACGTTATGATCCAATTGATATGATTTGGAAAAAAACAGACACTGTTGGAA
ATTTTATTTAGGATTTAAAA

Downstream 100 bases:

>100_bases
CATTTATTTTAATAAGTATGAATCGTTATGTTAAAGAATAAAAAAATACTTTTCATTGCGCCATCATTTTTTGGTTATGA
AAAAGACATCACTGATGAAT

Product: NAD dependent epimerase/dehydratase

Products: NA

Alternate protein names: UDP-glucuronic acid epimerase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTKNVLITGGAGFIGSNLALDLIDKGCNVTVLDNLSPQIHGENPELSPLYCSIKGKVRFIQGTVESRDDWLEALKDIDTV
VHLAAETGTGQSMYQIKKYSDINIGGSAIFLDLLANEPHNITKMVIASSRSIYGEGKYLCSEHGIVYPNARNDEDMKHDD
FNVKCPLCSINVELLATDEESKIHPSSIYGVTKQVQEQMFMITGESLDIPTVSLRFQNVYGAGQSLSNPYTGILSIFSTR
IKNGNDINIFEDGLESRDFVYIDDVVDSIVLSIFNENANYQIFNVGSGVCTDVLSVAETLKSVYESSSNILISSNYRVGD
IRHNFADLTLIKSKIGFEPKVDFVSGMRKFTAWVNQQEVQADLYESSIAEMKSKGLYK

Sequences:

>Translated_378_residues
MTKNVLITGGAGFIGSNLALDLIDKGCNVTVLDNLSPQIHGENPELSPLYCSIKGKVRFIQGTVESRDDWLEALKDIDTV
VHLAAETGTGQSMYQIKKYSDINIGGSAIFLDLLANEPHNITKMVIASSRSIYGEGKYLCSEHGIVYPNARNDEDMKHDD
FNVKCPLCSINVELLATDEESKIHPSSIYGVTKQVQEQMFMITGESLDIPTVSLRFQNVYGAGQSLSNPYTGILSIFSTR
IKNGNDINIFEDGLESRDFVYIDDVVDSIVLSIFNENANYQIFNVGSGVCTDVLSVAETLKSVYESSSNILISSNYRVGD
IRHNFADLTLIKSKIGFEPKVDFVSGMRKFTAWVNQQEVQADLYESSIAEMKSKGLYK
>Mature_377_residues
TKNVLITGGAGFIGSNLALDLIDKGCNVTVLDNLSPQIHGENPELSPLYCSIKGKVRFIQGTVESRDDWLEALKDIDTVV
HLAAETGTGQSMYQIKKYSDINIGGSAIFLDLLANEPHNITKMVIASSRSIYGEGKYLCSEHGIVYPNARNDEDMKHDDF
NVKCPLCSINVELLATDEESKIHPSSIYGVTKQVQEQMFMITGESLDIPTVSLRFQNVYGAGQSLSNPYTGILSIFSTRI
KNGNDINIFEDGLESRDFVYIDDVVDSIVLSIFNENANYQIFNVGSGVCTDVLSVAETLKSVYESSSNILISSNYRVGDI
RHNFADLTLIKSKIGFEPKVDFVSGMRKFTAWVNQQEVQADLYESSIAEMKSKGLYK

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1786974, Length=360, Percent_Identity=25.5555555555556, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=381, Percent_Identity=23.3595800524934, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19923002, Length=357, Percent_Identity=25.2100840336134, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.12 [H]

Molecular weight: Translated: 41786; Mature: 41654

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNVLITGGAGFIGSNLALDLIDKGCNVTVLDNLSPQIHGENPELSPLYCSIKGKVRFI
CCCCEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECEEEEE
QGTVESRDDWLEALKDIDTVVHLAAETGTGQSMYQIKKYSDINIGGSAIFLDLLANEPHN
EECCCCHHHHHHHHHHHHHHHEEHHCCCCCCHHEEEECCCCCCCCCCEEEEEECCCCCCC
ITKMVIASSRSIYGEGKYLCSEHGIVYPNARNDEDMKHDDFNVKCPLCSINVELLATDEE
CEEEEEECCCCCCCCCCEEECCCCEECCCCCCCCCCCCCCCEEECEEEEEEEEEEEECCC
SKIHPSSIYGVTKQVQEQMFMITGESLDIPTVSLRFQNVYGAGQSLSNPYTGILSIFSTR
CCCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHH
IKNGNDINIFEDGLESRDFVYIDDVVDSIVLSIFNENANYQIFNVGSGVCTDVLSVAETL
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
KSVYESSSNILISSNYRVGDIRHNFADLTLIKSKIGFEPKVDFVSGMRKFTAWVNQQEVQ
HHHHCCCCCEEEECCEEEECCCCCHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCHHHHH
ADLYESSIAEMKSKGLYK
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKNVLITGGAGFIGSNLALDLIDKGCNVTVLDNLSPQIHGENPELSPLYCSIKGKVRFI
CCCEEEECCCCCCCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECEEEEE
QGTVESRDDWLEALKDIDTVVHLAAETGTGQSMYQIKKYSDINIGGSAIFLDLLANEPHN
EECCCCHHHHHHHHHHHHHHHEEHHCCCCCCHHEEEECCCCCCCCCCEEEEEECCCCCCC
ITKMVIASSRSIYGEGKYLCSEHGIVYPNARNDEDMKHDDFNVKCPLCSINVELLATDEE
CEEEEEECCCCCCCCCCEEECCCCEECCCCCCCCCCCCCCCEEECEEEEEEEEEEEECCC
SKIHPSSIYGVTKQVQEQMFMITGESLDIPTVSLRFQNVYGAGQSLSNPYTGILSIFSTR
CCCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHH
IKNGNDINIFEDGLESRDFVYIDDVVDSIVLSIFNENANYQIFNVGSGVCTDVLSVAETL
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
KSVYESSSNILISSNYRVGDIRHNFADLTLIKSKIGFEPKVDFVSGMRKFTAWVNQQEVQ
HHHHCCCCCEEEECCEEEECCCCCHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCHHHHH
ADLYESSIAEMKSKGLYK
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]