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The map label for this gene is yqhT [H]

Identifier: 209696384

GI number: 209696384

Start: 3239242

End: 3241035

Strand: Reverse

Name: yqhT [H]

Synonym: VSAL_I2990

Alternate gene names: 209696384

Gene position: 3241035-3239242 (Counterclockwise)

Preceding gene: 209696385

Following gene: 209696383

Centisome position: 97.47

GC content: 43.48

Gene sequence:

>1794_bases
ATGCACCTACACACTTCTCAGCGTATTGAACAACTTCGCTCATGGCTTGCTCAACAACATTTAGATGCACTTATTATTCC
TCATGAAGATGAATTTTTAGGTGAATACATCCCTGAGCATAACGAACGTCTGTTATGGGCAACAGGATTCACCGGTTCAG
CTGGTGCCGCCGTCATAACAAAAGACAACGCCGCGATTTTTGTTGATGGCCGTTACACGGTTCAAGTTCGTAAACAAGTG
CCAGCAGAGGTATTTGAGTACCGTCATTTACATGAAGAACCTTTATTGGAGTGGATTAAAAATTCTCTACCTACTGGCTC
AAAAGTTGCCATCGACCCTCGTATGCATACCGCACAATGGTTACGTAATGCTAAAGCAGTTATTGAAGGACACGCCTCTC
TTGAGATGCTAAACAGTAATCCAATCGATCGCTTATGGTCAGATCGTCCAGCAGTTAAAGTGTCTGACGTTCGCTTAATG
GGATTAGCGCTTGTTGGTCAATCAAGCGCAGATAAACGTAAAGAAATTGCAGGTGTCATCGCAAATAAAAAGGCAGACGC
CGCCCTATTAACGCAACTTGATTCTATTTGTTGGTTACTGAATGTGCGTGGTTTGGATGTCTCTCGCCTTCCTGTTTTGT
TATCACACGCCATCATTCATGCTGACGAAAGTGTCGACTTTTTCCTAGACCCAACTCGTCTTCCTACCAACTTCATTGAA
CATGTAGGTCAAGGGGTTCGAATTCACAAACCTGACGCACTGCAATCGACTCTGCAATCGCTTGTTGGTCAAAAAGTCTT
GGTTGATTCAGCAACATCGAACGCATGGATGTCATTGATTCTATCTGACGCTAAAGCCGAAATTATAGAAGCTGCTGATC
CATGCCTATTACCAAAAGCAGCCAAAAACGAAACAGAAAAATCAGGAATGAAAGCGTGTCACATTCGTGATGGTGCCGCG
ATGGTTAAGTTTTTAACGTGGTTTGATGCAGAAATCGATGCAGGAAAATTGCATGATGAATCGGTACTTGCGGATAAACT
TCAAGGTTTCCGTGAAGAAGATGACACTTTGGCTGATTTAAGTTTTGATACCATTTCAGCCGCCGCAGGTAATGCATCGA
TGTGTCACTACAATCACGAAAACCAACCTGAGCCAGGTAAGCTACAAATGAACAGCTTATACCTTGTTGATTCAGGCGGC
CAATATCCAGATGGCACAACCGACATTACGCGTACACTTCCTGTTGGAACACCAAGTGATGACATCAAGCAGCAATTCAC
CCTTGTTCTAAAAGGCCACATTGGATTGGCATCAGCACGCTTTCCAAAAGGCACTTGTGGTCATCAGTTAGACATTCTTG
CTCGTCAACATTTATGGGCACAAGGCTACGACTATGATCATGGAACGGGTCACGGCGTTGGTCACTTCTTAAGTGTTCAT
GAAGGCCCACAGCGCATCGCTAAAGTCGTCAATAATACCGCTCTACTTCCGGGTATGGTTCTGTCTAATGAGCCGGGATA
TTACCGTGCAGATGAGTTTGGTATTCGTATTGAAAACTTAGAATTAGTTGTCGAAATAGAAACCAAAGGCGATTTCTCTG
TTCTTGGTTTTGAATCATTAACACGTTGCCCAATCGACAAACGTCTCATTAATGTTGATATGCTAAATCGCCCAGAACTG
GCTTGGTTAAATTCCTACCATCAGAAAGTGTGGAATGACGTCAGTCCATTAGTGAATGGCGAAGTAAAAGAATGGCTAAA
ACAAGCAACAGAAGCGCTTAGCTATGAAGACTAA

Upstream 100 bases:

>100_bases
CAATTGCAGACCACGAATAAAAGCACTAGGTTATAACCAAATAAAATCGATATTTTCTGCCTCTCCACATACGGACAGAT
CAATAATAAGGACACTTCAG

Downstream 100 bases:

>100_bases
TACATTGCTTTAAACAACTAAAATAATACGACCACGTAATCGACAGTGGTCGTATTATTGTCTAAAACGTTTCACGTGAA
ACATGCTTGTTATCACGCTG

Product: metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MHLHTSQRIEQLRSWLAQQHLDALIIPHEDEFLGEYIPEHNERLLWATGFTGSAGAAVITKDNAAIFVDGRYTVQVRKQV
PAEVFEYRHLHEEPLLEWIKNSLPTGSKVAIDPRMHTAQWLRNAKAVIEGHASLEMLNSNPIDRLWSDRPAVKVSDVRLM
GLALVGQSSADKRKEIAGVIANKKADAALLTQLDSICWLLNVRGLDVSRLPVLLSHAIIHADESVDFFLDPTRLPTNFIE
HVGQGVRIHKPDALQSTLQSLVGQKVLVDSATSNAWMSLILSDAKAEIIEAADPCLLPKAAKNETEKSGMKACHIRDGAA
MVKFLTWFDAEIDAGKLHDESVLADKLQGFREEDDTLADLSFDTISAAAGNASMCHYNHENQPEPGKLQMNSLYLVDSGG
QYPDGTTDITRTLPVGTPSDDIKQQFTLVLKGHIGLASARFPKGTCGHQLDILARQHLWAQGYDYDHGTGHGVGHFLSVH
EGPQRIAKVVNNTALLPGMVLSNEPGYYRADEFGIRIENLELVVEIETKGDFSVLGFESLTRCPIDKRLINVDMLNRPEL
AWLNSYHQKVWNDVSPLVNGEVKEWLKQATEALSYED

Sequences:

>Translated_597_residues
MHLHTSQRIEQLRSWLAQQHLDALIIPHEDEFLGEYIPEHNERLLWATGFTGSAGAAVITKDNAAIFVDGRYTVQVRKQV
PAEVFEYRHLHEEPLLEWIKNSLPTGSKVAIDPRMHTAQWLRNAKAVIEGHASLEMLNSNPIDRLWSDRPAVKVSDVRLM
GLALVGQSSADKRKEIAGVIANKKADAALLTQLDSICWLLNVRGLDVSRLPVLLSHAIIHADESVDFFLDPTRLPTNFIE
HVGQGVRIHKPDALQSTLQSLVGQKVLVDSATSNAWMSLILSDAKAEIIEAADPCLLPKAAKNETEKSGMKACHIRDGAA
MVKFLTWFDAEIDAGKLHDESVLADKLQGFREEDDTLADLSFDTISAAAGNASMCHYNHENQPEPGKLQMNSLYLVDSGG
QYPDGTTDITRTLPVGTPSDDIKQQFTLVLKGHIGLASARFPKGTCGHQLDILARQHLWAQGYDYDHGTGHGVGHFLSVH
EGPQRIAKVVNNTALLPGMVLSNEPGYYRADEFGIRIENLELVVEIETKGDFSVLGFESLTRCPIDKRLINVDMLNRPEL
AWLNSYHQKVWNDVSPLVNGEVKEWLKQATEALSYED
>Mature_597_residues
MHLHTSQRIEQLRSWLAQQHLDALIIPHEDEFLGEYIPEHNERLLWATGFTGSAGAAVITKDNAAIFVDGRYTVQVRKQV
PAEVFEYRHLHEEPLLEWIKNSLPTGSKVAIDPRMHTAQWLRNAKAVIEGHASLEMLNSNPIDRLWSDRPAVKVSDVRLM
GLALVGQSSADKRKEIAGVIANKKADAALLTQLDSICWLLNVRGLDVSRLPVLLSHAIIHADESVDFFLDPTRLPTNFIE
HVGQGVRIHKPDALQSTLQSLVGQKVLVDSATSNAWMSLILSDAKAEIIEAADPCLLPKAAKNETEKSGMKACHIRDGAA
MVKFLTWFDAEIDAGKLHDESVLADKLQGFREEDDTLADLSFDTISAAAGNASMCHYNHENQPEPGKLQMNSLYLVDSGG
QYPDGTTDITRTLPVGTPSDDIKQQFTLVLKGHIGLASARFPKGTCGHQLDILARQHLWAQGYDYDHGTGHGVGHFLSVH
EGPQRIAKVVNNTALLPGMVLSNEPGYYRADEFGIRIENLELVVEIETKGDFSVLGFESLTRCPIDKRLINVDMLNRPEL
AWLNSYHQKVWNDVSPLVNGEVKEWLKQATEALSYED

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=623, Percent_Identity=37.7207062600321, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI93141226, Length=610, Percent_Identity=34.5901639344262, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI264681565, Length=622, Percent_Identity=36.1736334405145, Blast_Score=347, Evalue=1e-95,
Organism=Escherichia coli, GI1788728, Length=306, Percent_Identity=28.4313725490196, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509539, Length=619, Percent_Identity=33.6025848142165, Blast_Score=316, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI25149105, Length=595, Percent_Identity=31.2605042016807, Blast_Score=263, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6322999, Length=659, Percent_Identity=30.0455235204856, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI17137632, Length=625, Percent_Identity=36, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI161078230, Length=582, Percent_Identity=27.8350515463918, Blast_Score=240, Evalue=3e-63,
Organism=Drosophila melanogaster, GI21357287, Length=582, Percent_Identity=27.8350515463918, Blast_Score=240, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 66283; Mature: 66283

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLHTSQRIEQLRSWLAQQHLDALIIPHEDEFLGEYIPEHNERLLWATGFTGSAGAAVIT
CCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEE
KDNAAIFVDGRYTVQVRKQVPAEVFEYRHLHEEPLLEWIKNSLPTGSKVAIDPRMHTAQW
ECCEEEEECCEEEEEEHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCHHHHHH
LRNAKAVIEGHASLEMLNSNPIDRLWSDRPAVKVSDVRLMGLALVGQSSADKRKEIAGVI
HHHHHHHHCCCCCEEEECCCCHHHHHCCCCCEEEECEEEEEEEEECCCCCHHHHHHHHHH
ANKKADAALLTQLDSICWLLNVRGLDVSRLPVLLSHAIIHADESVDFFLDPTRLPTNFIE
HCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
HVGQGVRIHKPDALQSTLQSLVGQKVLVDSATSNAWMSLILSDAKAEIIEAADPCLLPKA
HCCCCCEEECCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
AKNETEKSGMKACHIRDGAAMVKFLTWFDAEIDAGKLHDESVLADKLQGFREEDDTLADL
HCCCCHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHC
SFDTISAAAGNASMCHYNHENQPEPGKLQMNSLYLVDSGGQYPDGTTDITRTLPVGTPSD
CHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEECCCCCCCH
DIKQQFTLVLKGHIGLASARFPKGTCGHQLDILARQHLWAQGYDYDHGTGHGVGHFLSVH
HHHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHEECC
EGPQRIAKVVNNTALLPGMVLSNEPGYYRADEFGIRIENLELVVEIETKGDFSVLGFESL
CCHHHHHHHHCCCCCCCCEEECCCCCCEECHHHCEEEECEEEEEEEECCCCEEEECHHHH
TRCPIDKRLINVDMLNRPELAWLNSYHQKVWNDVSPLVNGEVKEWLKQATEALSYED
HCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHLHTSQRIEQLRSWLAQQHLDALIIPHEDEFLGEYIPEHNERLLWATGFTGSAGAAVIT
CCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEE
KDNAAIFVDGRYTVQVRKQVPAEVFEYRHLHEEPLLEWIKNSLPTGSKVAIDPRMHTAQW
ECCEEEEECCEEEEEEHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCHHHHHH
LRNAKAVIEGHASLEMLNSNPIDRLWSDRPAVKVSDVRLMGLALVGQSSADKRKEIAGVI
HHHHHHHHCCCCCEEEECCCCHHHHHCCCCCEEEECEEEEEEEEECCCCCHHHHHHHHHH
ANKKADAALLTQLDSICWLLNVRGLDVSRLPVLLSHAIIHADESVDFFLDPTRLPTNFIE
HCCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHH
HVGQGVRIHKPDALQSTLQSLVGQKVLVDSATSNAWMSLILSDAKAEIIEAADPCLLPKA
HCCCCCEEECCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
AKNETEKSGMKACHIRDGAAMVKFLTWFDAEIDAGKLHDESVLADKLQGFREEDDTLADL
HCCCCHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHC
SFDTISAAAGNASMCHYNHENQPEPGKLQMNSLYLVDSGGQYPDGTTDITRTLPVGTPSD
CHHHHHHCCCCCCEEECCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEECCCCCCCH
DIKQQFTLVLKGHIGLASARFPKGTCGHQLDILARQHLWAQGYDYDHGTGHGVGHFLSVH
HHHHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHEECC
EGPQRIAKVVNNTALLPGMVLSNEPGYYRADEFGIRIENLELVVEIETKGDFSVLGFESL
CCHHHHHHHHCCCCCCCCEEECCCCCCEECHHHCEEEECEEEEEEEECCCCEEEECHHHH
TRCPIDKRLINVDMLNRPELAWLNSYHQKVWNDVSPLVNGEVKEWLKQATEALSYED
HCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]