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The map label for this gene is trkH [H]

Identifier: 209696370

GI number: 209696370

Start: 3223557

End: 3225014

Strand: Direct

Name: trkH [H]

Synonym: VSAL_I2976

Alternate gene names: 209696370

Gene position: 3223557-3225014 (Clockwise)

Preceding gene: 209696369

Following gene: 209696371

Centisome position: 96.94

GC content: 41.63

Gene sequence:

>1458_bases
ATGCAGTTTCGATCAATAATCCGCATTGTGGGTATTTTACTCGCGGTGTTCAGTTTTTTCATGTTAGCTCCCGCTCTTGT
CGCGTTTATTTATCGTGATGGTGCTGGTGTGCCTTTTGTTATTACTTTTTTCTTGTTACTTGCCGGTGGAGGGCTACTTT
GGTTCCCCAATAGACAGCATAAACAAGAGTTAAAATCTCGCGATGGGTTTCTCATTGTGGTCTTATTTTGGATGGTAATT
GGTAGTGCGGGTGCATTGCCGTTTTTATTATCTGGTTCACCTGATATTTCGATAACCAATGCCTTTTTTGAGTCCTTTTC
TGGTTTGACGACAACAGGTGCTACCGTTCTTACGGGATTAGACCACTTACCAAAAGCGATTTTATTCTATCGACAACTGC
TTCAGTGGTTTGGCGGTATGGGTATCATTGTACTCGCCGTTGCGATTCTTCCTGTTCTTGGTATCGGTGGGATGCAGCTT
TATCGTGCTGAAATCCCTGGGCCGGTAAAAGATTCTAAGATGACTCCGCGAATAGCTGAAACGGCTAAGGTGCTTTGGTA
TATCTACTTAACATTAACCATTGCTTGTACATTGGCATTTTGGGCGGCGGGGATGGATTGGTTTGACGCCATCACTCATA
GTTTCTCAACAATTGCTATTGGTGGTTTCTCTACCCATGATGCCAGTATGGGGTATTTCAATAGCCCCGTAATTAATGCC
ATTACAGTGGTGTTTTTACTTATTTCAGCGTGTAACTTCTCTCTACACTTTGCCGCTTTTGCGTCTGGTGGTGTGCATCC
CAAGTATTATTGGAAAGATCCAGAATTCAGAGCATTTATCTTCATTCAAGTGTTGTTATTTTTAATTACGTTTTTGTTGT
TATTAAAACACAGTACTTATGATTCGATTGGTACTGCGGTTGATCAGGCGTTATTTCAAACCGTTTCTATCTCAACAACG
GCGGGTTTTACAACCACCAGTTTTGCTGAGTGGCCATTATTTTTACCTGTGTTGTTGCTGTTTTCTTCATTTATTGGTGG
TTGTGCGGGGTCTACTGGCGGCGGAATGAAAGTGATACGTATTTTGTTACTGTCATTACAAGGAATGCGTGAGCTTAAAC
GATTGATTCACCCAAGAGCCATTTATACGATTAAGATTGGCAGCAAGGCATTACCACAACGAGTGGTTGATGCTGTATGG
GGATTTTTCTCTGCTTATACATTAGTGTTCGTCATTTGTATGTTGGCATTGATTGCGACAGGCATTGATGAATTGACCGC
ATTCTCAGCGGTGGCGGCAACATTAAACAATTTAGGGCCTGGTTTAGGTGAGGTTGCTGTACACTTTGGTGATATAAATG
ATTCAGCGAAATGGATTTTAATCATCTCGATGTTATTTGGTCGTTTGGAAGTGTTTACACTCCTTATTTTATTTACGCCG
ACGTTTTGGCGTAGTTAA

Upstream 100 bases:

>100_bases
GATTAATAAAAGCGGGGCCAAAATTGAATTTCCAACACAATAATAAATTCAATTCATATAAACCATTAGGATGTGAGTGA
CGCGAAGCGTTTAATAAATC

Downstream 100 bases:

>100_bases
CACTCAAGATTAATAAAAGAGGTTATTGTGGAAAAAGTATTACTTCTTCATTCGAGCCGTGAAGGTCAAACGATTAAAAT
TTTGAATTACATAGCAACGA

Product: Trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MQFRSIIRIVGILLAVFSFFMLAPALVAFIYRDGAGVPFVITFFLLLAGGGLLWFPNRQHKQELKSRDGFLIVVLFWMVI
GSAGALPFLLSGSPDISITNAFFESFSGLTTTGATVLTGLDHLPKAILFYRQLLQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKVLWYIYLTLTIACTLAFWAAGMDWFDAITHSFSTIAIGGFSTHDASMGYFNSPVINA
ITVVFLLISACNFSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVLLFLITFLLLLKHSTYDSIGTAVDQALFQTVSISTT
AGFTTTSFAEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLSLQGMRELKRLIHPRAIYTIKIGSKALPQRVVDAVW
GFFSAYTLVFVICMLALIATGIDELTAFSAVAATLNNLGPGLGEVAVHFGDINDSAKWILIISMLFGRLEVFTLLILFTP
TFWRS

Sequences:

>Translated_485_residues
MQFRSIIRIVGILLAVFSFFMLAPALVAFIYRDGAGVPFVITFFLLLAGGGLLWFPNRQHKQELKSRDGFLIVVLFWMVI
GSAGALPFLLSGSPDISITNAFFESFSGLTTTGATVLTGLDHLPKAILFYRQLLQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKVLWYIYLTLTIACTLAFWAAGMDWFDAITHSFSTIAIGGFSTHDASMGYFNSPVINA
ITVVFLLISACNFSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVLLFLITFLLLLKHSTYDSIGTAVDQALFQTVSISTT
AGFTTTSFAEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLSLQGMRELKRLIHPRAIYTIKIGSKALPQRVVDAVW
GFFSAYTLVFVICMLALIATGIDELTAFSAVAATLNNLGPGLGEVAVHFGDINDSAKWILIISMLFGRLEVFTLLILFTP
TFWRS
>Mature_485_residues
MQFRSIIRIVGILLAVFSFFMLAPALVAFIYRDGAGVPFVITFFLLLAGGGLLWFPNRQHKQELKSRDGFLIVVLFWMVI
GSAGALPFLLSGSPDISITNAFFESFSGLTTTGATVLTGLDHLPKAILFYRQLLQWFGGMGIIVLAVAILPVLGIGGMQL
YRAEIPGPVKDSKMTPRIAETAKVLWYIYLTLTIACTLAFWAAGMDWFDAITHSFSTIAIGGFSTHDASMGYFNSPVINA
ITVVFLLISACNFSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVLLFLITFLLLLKHSTYDSIGTAVDQALFQTVSISTT
AGFTTTSFAEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIRILLLSLQGMRELKRLIHPRAIYTIKIGSKALPQRVVDAVW
GFFSAYTLVFVICMLALIATGIDELTAFSAVAATLNNLGPGLGEVAVHFGDINDSAKWILIISMLFGRLEVFTLLILFTP
TFWRS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=69.2783505154639, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=41.7355371900826, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53099; Mature: 53099

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFRSIIRIVGILLAVFSFFMLAPALVAFIYRDGAGVPFVITFFLLLAGGGLLWFPNRQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCHHH
KQELKSRDGFLIVVLFWMVIGSAGALPFLLSGSPDISITNAFFESFSGLTTTGATVLTGL
HHHHHCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
DHLPKAILFYRQLLQWFGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCCHHHH
TAKVLWYIYLTLTIACTLAFWAAGMDWFDAITHSFSTIAIGGFSTHDASMGYFNSPVINA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHH
ITVVFLLISACNFSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVLLFLITFLLLLKHSTY
HHHHHHHHHHHCCHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
DSIGTAVDQALFQTVSISTTAGFTTTSFAEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ILLLSLQGMRELKRLIHPRAIYTIKIGSKALPQRVVDAVWGFFSAYTLVFVICMLALIAT
HHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIDELTAFSAVAATLNNLGPGLGEVAVHFGDINDSAKWILIISMLFGRLEVFTLLILFTP
CHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRS
HHCCC
>Mature Secondary Structure
MQFRSIIRIVGILLAVFSFFMLAPALVAFIYRDGAGVPFVITFFLLLAGGGLLWFPNRQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCHHH
KQELKSRDGFLIVVLFWMVIGSAGALPFLLSGSPDISITNAFFESFSGLTTTGATVLTGL
HHHHHCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
DHLPKAILFYRQLLQWFGGMGIIVLAVAILPVLGIGGMQLYRAEIPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHEECCCCCCCCCCCCCCCHHHH
TAKVLWYIYLTLTIACTLAFWAAGMDWFDAITHSFSTIAIGGFSTHDASMGYFNSPVINA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHH
ITVVFLLISACNFSLHFAAFASGGVHPKYYWKDPEFRAFIFIQVLLFLITFLLLLKHSTY
HHHHHHHHHHHCCHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
DSIGTAVDQALFQTVSISTTAGFTTTSFAEWPLFLPVLLLFSSFIGGCAGSTGGGMKVIR
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ILLLSLQGMRELKRLIHPRAIYTIKIGSKALPQRVVDAVWGFFSAYTLVFVICMLALIAT
HHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIDELTAFSAVAATLNNLGPGLGEVAVHFGDINDSAKWILIISMLFGRLEVFTLLILFTP
CHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWRS
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]