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The map label for this gene is uspA [H]

Identifier: 209696343

GI number: 209696343

Start: 3192315

End: 3192740

Strand: Reverse

Name: uspA [H]

Synonym: VSAL_I2946

Alternate gene names: 209696343

Gene position: 3192740-3192315 (Counterclockwise)

Preceding gene: 209696350

Following gene: 209696341

Centisome position: 96.02

GC content: 37.79

Gene sequence:

>426_bases
ATGAGCTATAAACATATTCTTGTTGCTGTCGATTTAACAGAAGAGAGTAAGTCACTGGTCACTAAAGCGGTTGGTTTAGC
CAAGGCTCTTGATGCGAAAGTCTCTTTTATTCACATTGATGTTAGCTATGCAGAATTATATACCGGATTAATTGATATTA
ATCTGGCTGAAACACAACACCAAGCAATGGAAGCATCGCACGAAGCCATGAAGCATTTAGTGACCTTTGCAGATTATCCA
ATTCATAAAACATTGGTAAGTAGTGGGGATCTAAGCAGTGAGTTGTGCGAAGCAATTGAAAACTTAGATGTAAACCTTGT
GGTTTGTGGTCATCACCAAGATTTCTGGAGTAAATTATTATCATCAACCAGACAAGTGATCAACACCTGTCCAATTGACG
TTCTTGTTGTGCCATTTAAAGATTAA

Upstream 100 bases:

>100_bases
CGACAAAAAAAGAGAAAGACTGGTGCTAATCTATAGATAATCCATCTTAAATATCGAATTCAAAAGGGATTTAACTTTTG
GATTACCTAGGAGATAAATT

Downstream 100 bases:

>100_bases
GACTTCATTCCAGCGTTAACATACACATCGAAACGATTCTTCTTCGTTTCAATCGCCATCGAAGGCTTTTGATTATCTAG
CCATTCAGCATAATCAGGAC

Product: universal stress protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MSYKHILVAVDLTEESKSLVTKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQHQAMEASHEAMKHLVTFADYP
IHKTLVSSGDLSSELCEAIENLDVNLVVCGHHQDFWSKLLSSTRQVINTCPIDVLVVPFKD

Sequences:

>Translated_141_residues
MSYKHILVAVDLTEESKSLVTKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQHQAMEASHEAMKHLVTFADYP
IHKTLVSSGDLSSELCEAIENLDVNLVVCGHHQDFWSKLLSSTRQVINTCPIDVLVVPFKD
>Mature_140_residues
SYKHILVAVDLTEESKSLVTKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQHQAMEASHEAMKHLVTFADYPI
HKTLVSSGDLSSELCEAIENLDVNLVVCGHHQDFWSKLLSSTRQVINTCPIDVLVVPFKD

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=141, Percent_Identity=58.8652482269503, Blast_Score=178, Evalue=1e-46,
Organism=Escherichia coli, GI1790358, Length=141, Percent_Identity=34.7517730496454, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1788205, Length=140, Percent_Identity=35, Blast_Score=83, Evalue=8e-18,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15580; Mature: 15449

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKHILVAVDLTEESKSLVTKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQH
CCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHEEEEHHHHH
QAMEASHEAMKHLVTFADYPIHKTLVSSGDLSSELCEAIENLDVNLVVCGHHQDFWSKLL
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHH
SSTRQVINTCPIDVLVVPFKD
HHHHHHHHHCCEEEEEEECCC
>Mature Secondary Structure 
SYKHILVAVDLTEESKSLVTKAVGLAKALDAKVSFIHIDVSYAELYTGLIDINLAETQH
CCCEEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEEEEEHHHHHHHHHHEEEEHHHHH
QAMEASHEAMKHLVTFADYPIHKTLVSSGDLSSELCEAIENLDVNLVVCGHHQDFWSKLL
HHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHH
SSTRQVINTCPIDVLVVPFKD
HHHHHHHHHCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]