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The map label for this gene is rpoC [H]

Identifier: 209696265

GI number: 209696265

Start: 3100411

End: 3104616

Strand: Reverse

Name: rpoC [H]

Synonym: VSAL_I2865

Alternate gene names: 209696265

Gene position: 3104616-3100411 (Counterclockwise)

Preceding gene: 209696266

Following gene: 209696263

Centisome position: 93.37

GC content: 43.25

Gene sequence:

>4206_bases
GTGAAAGACTTATTAAAGTTTCTGAAAGCACAACATAAGACCGAAGAATTTGATGCAATCAAAATCGGTCTTGCTTCACC
TGACCAAATTCGTTCATGGTCTTTTGGTGAAGTTAAAAAGCCAGAAACAATCAACTATCGTACCTTTAAGCCAGAACGTG
ACGGTCTTTTCTGTGCACGTATCTTTGGCCCAGTGAAAGACTACGAGTGCTTATGTGGTAAATATAAGCGCCTGAAGCAC
CGTGGTGTTATCTGTGAAAAATGTGGCGTAGAAGTAACGCAAACTAAAGTTCGTCGTGACCGTATGGGTCATATTGAACT
TGCGTCTCCTGTTGCACACATCTGGTTCCTTAAGTCACTTCCGTCTCGTATTGGTTTGTTAATGGACATCCCTCTGCGTG
ATATCGAACGTGTACTTTATTTTGAATCATATGTGGTTACAGAGCCAGGTATGACTGACTTAGAGCGCAGCCAACTTCTT
TCAGAAGAAGAATATCTTGATAAGCTTGAAGAGTTCGGTGACGAATTCACAGCTAAGATGGGTGCGGAAGCGATTAAAGA
CTTGCTTGGTTCTATGGACATGCAAGCTGAAATCGAGAACATGCGTGAAGAGTTAGAAACAACTAACTCAGAAACAAAAC
GTAAGAAGCTGACTAAGCGTTTAAAACTTGTAGAAGCATTTGTTCAATCTGGTAACAACCCAGAATGGATGATCTTAACT
GTTCTACCTGTTCTTCCGCCAGATCTTCGTCCTCTAGTTCCACTAGATGGCGGTCGTTTTGCTACGTCTGATCTAAATGA
TTTATACCGTCGTGTGATTAACCGTAACAACCGTTTGAAGCGTCTTTTAGACTTAGCTGCACCAGACATCATCGTACGTA
ATGAAAAACGTATGCTGCAAGAGTCTGTTGATGCGCTGCTTGATAACGGTCGTCGTGGTCGTGCGATTACAGGTTCTAAC
AAGCGTCCTTTGAAATCTCTTGCTGATATGATCAAGGGTAAACAAGGTCGTTTCCGTCAGAACTTGCTTGGTAAACGTGT
AGACTACTCTGGTCGTTCTGTTATTACAGTAGGTCCATACCTTCGTCTACATCAGTGTGGTCTTCCTAAGAAGATGGCAC
TTGAATTATTTAAACCATTTATTTATAGCAAATTAGAAGGTCGTGGTTTTGCTACGACAATCAAAGCTGCTAAGAAAATG
GTAGAGCGTGAAGAAGCGATCGTTTGGGATATCCTAGATGACGTTATTCGTGAACACCCAGTACTGCTTAACCGTGCACC
AACACTTCACCGTCTTGGTATTCAAGCGTTTGAACCAGTACTAATCGAAGGTAAAGCGATTCAGCTGCACCCATTAGTGT
GTGCGGCATATAATGCCGATTTCGATGGTGACCAGATGGCGGTACACGTACCACTAACTCTGGAAGCTCAGCTAGAAGCT
CGTACCCTAATGATGTCGACGAATAATATTCTGTCGCCAGCATCAGGTGATCCAATCATCGTTCCTTCTCAGGATGTTGT
ATTAGGTCTGTACTACATGACGCGTGACAGAATTAACGCGAAAGGCGAAGGCATGTACCTAGAAGGTTTTGCTGAAGCTG
AAAAAGCATACCGTACAGGTAATGCTGAGCTACATGCTCGCGTTAAAGTTCGTATCACAGAAGTTCTTCGTGATGAGAAC
GGTATTGAAACTCGTGAAACTAAACTGGTTGATACGACTGTTGGTCGTGCAATGCTATGGCAGATCGTTCCTGAAGGTCT
TCCTTACAGCATCATTAACCAGAAGTTAGGTAAGAAGCAAATCTCTAACCTATTAAACGAGGCATATCGTACTCTTGGTT
CTAAAGATACAGTAATCTTTGCAGACCAAATCATGTACACCGGTTTCGCATACGCGGCATTGTCTGGTGCGTCTGTTGGT
ATCGATGACATGGTTATCCCTGATGCTAAGTATACGAAAGTTGCTGAAGCAGAAGAAGAAGTTAAGCAAATTCAAGAACA
ATATCAATCTGGTCTTGTAACTGCTGGCGAACGTTACAACAAAGTTATCGATATCTGGGCAGCAACGAATGAACAAGTTG
CTAAAGAGATGATGGATAACTTGTCTTCAGAAACTGTGCTTAACCGCGATGGTGAAGAAGAGCAACAAGAATCGTTTAAC
AGCGTTTACATGATGGCCGATTCAGGTGCTCGTGGTTCTGCAGCTCAGATTCGTCAGCTTGCAGGTATGCGTGGTCTGAT
GGCGAAACCAGATGGTTCAATCATCGAAACACCGATCACGGCGAACTTCCGTGAAGGTCTAAACGTAAACCAATATTTCA
TCTCAACGCATGGTGCGCGTAAAGGTCTTGCCGATACTGCACTTAAAACAGCGAACTCAGGTTACCTGACTCGTCGTTTA
GTAGACGTTGCTCAAGATGTAGTCGTTCATTTAGATGACTGTGGAACACTTGAAGGTGTTACCATGATGCCTCTAATTGA
AGGTGGTGATGTTAAAGAACCTCTACATGAACGTGTTCTAGGTCGTGTCGTTGCTGAAGATGTATTGAAACCAGGTACTG
ATGAGATCCTTCTTCCACGTAACACGCTTCTTGATGAGAAGCAGTGTCAAATCGTTGAAGAAAACTCAGTTGACCAAATC
AAAGTACGTTCAGTTGTAAGTTGTGAAGCTGACTTCGGTTGTTGTGCAAACTGTTATGGCCGTGACCTTGCTCGTGGACA
CATGGTAAACCAAGGTGAGGCAGTCGGTGTTATTGCGGCTCAGTCTATTGGTGAACCTGGTACACAGCTTACGATGCGTA
CGTTCCATATCGGTGGTGCGGCATCTACAGCAGCAGCAGACAACAGCATTCAAGTTAAGACGACAGGTTCGATTAAACTT
CATAATGCTAAGCACGTAACGAATAACGAAGGCAACCTAGTTATTACTTCTCGTGCATCTCAACTGACGGTTATTGATGG
GCATGGTCGTACGAAAGAAAGCTACAAGCTATCTTACGGTACTATTCTTTCTAAGAAAGATGGTGATGTTGTGACTCAAG
GCGATAAGATCGCAGCTTGGGACCCGCATACAATGCCAATCATCACAGAAGTAAAAGGTCAAGTTCAATTCGTTGATATG
ATTGATGGTGTGACTATTACAACTCAAACTGATGAGTTAACTGGTCTATCGTCAATTGTTATCCTTGATACGGCTGAGCG
TGCTTCTGCTGGTAAAGACATGCGTCCAACAGTGAAACTTGTTGATGCGAATGGTCGTGACATCATGATCCCTGGCACTG
AAATGCCAGCTCAATACTTCCTACCAGGTAAAGCAATTGTTAACTTGGCTGATGGTGGCGATGTAGGTATCGGTGAAACA
CTGGCTCGTATTCCTCAAGCTTCAAGTGGTACTAAAGATATTACCGGTGGTCTTCCACGCGTTGCGGATTTATTTGAAGC
TCGTAAACCTAAAGAGCCAGCAATTCTTGCTGAGCACGCAGGTATCGTTGCTTTTGGTAAAGAAACGAAAGGTAAAGTAC
GCTTATTGATCACTCGTGATGATACTGGTGAAGTTTATGAAGAAATGATTCATAAACATCGTCAACTTAACATTTTTGAT
GGTGATAAAGTTGAACGCGGTGACGTTATTTCTGATGGTCCAGAAACACCACATGATATTCTACGTTTACGTGGTATTCA
TGCCGTTACTGAATACATCACAAACGAAGTTCAAGAAGTTTACCGTTTACAAGGCGTTAAGATTAACGATAAGCACATTG
AGACTATCGTTCGTCAAATGCTACGTAAGTGTACTATCACACATTCTGGTGACTCTACTTTCCTTGAAGGTGAGCAACTA
GAATTTGCAAACGTAACTATTGCAAACCGTCAGCTTGAAGCTGAAGGAAAGCAACCAGCTCGTTTTGGTCGTGATTTACT
AGGTATTACTAAAGCGTCTCTTGCTACTGAGTCGTTCATCTCTGCTGCATCGTTCCAAGAAACGACGCGCGTACTTACTG
AGGCTGCGGTTTCTGGTAAGCGTGATGAACTACGTGGTCTGAAAGAAAACGTAATCGTTGGTCGTCTAATTCCAGCGGGT
ACAGGTTTCTCATACCACCAAGCACGTCAAAAGCAAAAAGCAGCAGCGAAAGTTGCGCCTTCTGCTGAAGAAGCAACAGA
TAACTTAGCGGCACTATTGAATGCGGGTTTCTCTTCTGAAGAGTAA

Upstream 100 bases:

>100_bases
TCAACATCGAGTTAGAAGACGAAGAATAATCTCATTGAGATTGTCCGGTAGAATATAAGGCGCTCGCCGAGCGCCTTTTT
TCTCCTTACAGGAGCCGAAT

Downstream 100 bases:

>100_bases
TTAGTTTTAATATTCGCTAAATAAAAAGCCCTACAGAAATGCAGGGCTTTTTTTATATTTAAACGTATGTGTGATTATAA
CTGTGTGATTAAAACAACGT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1401; Mature: 1401

Protein sequence:

>1401_residues
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLL
SEEEYLDKLEEFGDEFTAKMGAEAIKDLLGSMDMQAEIENMREELETTNSETKRKKLTKRLKLVEAFVQSGNNPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLEGRGFATTIKAAKKM
VEREEAIVWDILDDVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDRINAKGEGMYLEGFAEAEKAYRTGNAELHARVKVRITEVLRDEN
GIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQISNLLNEAYRTLGSKDTVIFADQIMYTGFAYAALSGASVG
IDDMVIPDAKYTKVAEAEEEVKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDVVVHLDDCGTLEGVTMMPLIEGGDVKEPLHERVLGRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQI
KVRSVVSCEADFGCCANCYGRDLARGHMVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HNAKHVTNNEGNLVITSRASQLTVIDGHGRTKESYKLSYGTILSKKDGDVVTQGDKIAAWDPHTMPIITEVKGQVQFVDM
IDGVTITTQTDELTGLSSIVILDTAERASAGKDMRPTVKLVDANGRDIMIPGTEMPAQYFLPGKAIVNLADGGDVGIGET
LARIPQASSGTKDITGGLPRVADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDTGEVYEEMIHKHRQLNIFD
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSGDSTFLEGEQL
EFANVTIANRQLEAEGKQPARFGRDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAG
TGFSYHQARQKQKAAAKVAPSAEEATDNLAALLNAGFSSEE

Sequences:

>Translated_1401_residues
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLL
SEEEYLDKLEEFGDEFTAKMGAEAIKDLLGSMDMQAEIENMREELETTNSETKRKKLTKRLKLVEAFVQSGNNPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLEGRGFATTIKAAKKM
VEREEAIVWDILDDVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDRINAKGEGMYLEGFAEAEKAYRTGNAELHARVKVRITEVLRDEN
GIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQISNLLNEAYRTLGSKDTVIFADQIMYTGFAYAALSGASVG
IDDMVIPDAKYTKVAEAEEEVKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDVVVHLDDCGTLEGVTMMPLIEGGDVKEPLHERVLGRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQI
KVRSVVSCEADFGCCANCYGRDLARGHMVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HNAKHVTNNEGNLVITSRASQLTVIDGHGRTKESYKLSYGTILSKKDGDVVTQGDKIAAWDPHTMPIITEVKGQVQFVDM
IDGVTITTQTDELTGLSSIVILDTAERASAGKDMRPTVKLVDANGRDIMIPGTEMPAQYFLPGKAIVNLADGGDVGIGET
LARIPQASSGTKDITGGLPRVADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDTGEVYEEMIHKHRQLNIFD
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSGDSTFLEGEQL
EFANVTIANRQLEAEGKQPARFGRDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAG
TGFSYHQARQKQKAAAKVAPSAEEATDNLAALLNAGFSSEE
>Mature_1401_residues
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSLPSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLL
SEEEYLDKLEEFGDEFTAKMGAEAIKDLLGSMDMQAEIENMREELETTNSETKRKKLTKRLKLVEAFVQSGNNPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYSKLEGRGFATTIKAAKKM
VEREEAIVWDILDDVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDRINAKGEGMYLEGFAEAEKAYRTGNAELHARVKVRITEVLRDEN
GIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQISNLLNEAYRTLGSKDTVIFADQIMYTGFAYAALSGASVG
IDDMVIPDAKYTKVAEAEEEVKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDVVVHLDDCGTLEGVTMMPLIEGGDVKEPLHERVLGRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQI
KVRSVVSCEADFGCCANCYGRDLARGHMVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HNAKHVTNNEGNLVITSRASQLTVIDGHGRTKESYKLSYGTILSKKDGDVVTQGDKIAAWDPHTMPIITEVKGQVQFVDM
IDGVTITTQTDELTGLSSIVILDTAERASAGKDMRPTVKLVDANGRDIMIPGTEMPAQYFLPGKAIVNLADGGDVGIGET
LARIPQASSGTKDITGGLPRVADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDTGEVYEEMIHKHRQLNIFD
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQMLRKCTITHSGDSTFLEGEQL
EFANVTIANRQLEAEGKQPARFGRDLLGITKASLATESFISAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAG
TGFSYHQARQKQKAAAKVAPSAEEATDNLAALLNAGFSSEE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=910, Percent_Identity=26.7032967032967, Blast_Score=211, Evalue=6e-54,
Organism=Homo sapiens, GI39725938, Length=307, Percent_Identity=31.9218241042345, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI103471997, Length=597, Percent_Identity=26.1306532663317, Blast_Score=117, Evalue=7e-26,
Organism=Escherichia coli, GI2367335, Length=1405, Percent_Identity=81.423487544484, Blast_Score=2350, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=905, Percent_Identity=26.0773480662983, Blast_Score=191, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI25145495, Length=676, Percent_Identity=26.4792899408284, Blast_Score=186, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6320061, Length=648, Percent_Identity=26.5432098765432, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324690, Length=732, Percent_Identity=25.2732240437158, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324917, Length=282, Percent_Identity=28.0141843971631, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17530899, Length=968, Percent_Identity=24.3801652892562, Blast_Score=199, Evalue=2e-50,
Organism=Drosophila melanogaster, GI281360912, Length=881, Percent_Identity=24.1770715096481, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17647875, Length=339, Percent_Identity=28.3185840707965, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 154955; Mature: 154955

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
PSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLLSEEEYLDKLEEFGDEFTAKM
HHHCCEEEECCHHHHHHHHHHHHEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GAEAIKDLLGSMDMQAEIENMREELETTNSETKRKKLTKRLKLVEAFVQSGNNPEWMILT
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYSKLEGRGFATTIKAAKKMVEREEAIVWDILDDVIREHP
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
EEECCCCCHHHHCHHHCCCEEEECCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCCCE
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDRINAKGEGMYLEGFAEAEKAYRTG
EEEEEECCCCCCCCCCCEEEECCCHHEEEEHHHHHHCCCCCCCCEEEECHHHHHHHHHCC
NAELHARVKVRITEVLRDENGIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQ
CCEEEEEEEEEEHHHHHCCCCCCHHHHEEHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHH
ISNLLNEAYRTLGSKDTVIFADQIMYTGFAYAALSGASVGIDDMVIPDAKYTKVAEAEEE
HHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHH
VKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
HHHHHHHHHCCCEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHCCCCCHHHHHCCC
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHCCCCCCEEEEECCCCC
KGLADTALKTANSGYLTRRLVDVAQDVVVHLDDCGTLEGVTMMPLIEGGDVKEPLHERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCCHHHHHHHH
GRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQIKVRSVVSCEADFGCCANCYG
HHHHHHHHHCCCCCCEEECCHHHCCCHHHHEECCCCCCCEEHHHHEECCCCCCCHHHHHH
RDLARGHMVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECCCEEE
HNAKHVTNNEGNLVITSRASQLTVIDGHGRTKESYKLSYGTILSKKDGDVVTQGDKIAAW
ECCCEEECCCCCEEEEECCCEEEEECCCCCCCCCEEEEEEEEEECCCCCEEECCCEEEEC
DPHTMPIITEVKGQVQFVDMIDGVTITTQTDELTGLSSIVILDTAERASAGKDMRPTVKL
CCCCCCEEEECCCCEEEEEECCCEEEEECCHHHCCCCEEEEEECHHHHCCCCCCCCEEEE
VDANGRDIMIPGTEMPAQYFLPGKAIVNLADGGDVGIGETLARIPQASSGTKDITGGLPR
EECCCCEEEECCCCCCHHHCCCCHHEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDTGEVYEEMIHKHRQLNIFD
HHHHHHHCCCCCCCEEECCCCEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHCEEEEEC
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRKCTITHSGDSTFLEGEQLEFANVTIANRQLEAEGKQPARFGRDLLGITKASLATESFI
HHHCCEEECCCCCEECCCCEEEEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAGTGFSYHQARQKQKAAAKVAP
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
SAEEATDNLAALLNAGFSSEE
CHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKDLLKFLKAQHKTEEFDAIKIGLASPDQIRSWSFGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRDRMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHH
PSRIGLLMDIPLRDIERVLYFESYVVTEPGMTDLERSQLLSEEEYLDKLEEFGDEFTAKM
HHHCCEEEECCHHHHHHHHHHHHEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GAEAIKDLLGSMDMQAEIENMREELETTNSETKRKKLTKRLKLVEAFVQSGNNPEWMILT
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYSKLEGRGFATTIKAAKKMVEREEAIVWDILDDVIREHP
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
EEECCCCCHHHHCHHHCCCEEEECCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCCCE
RTLMMSTNNILSPASGDPIIVPSQDVVLGLYYMTRDRINAKGEGMYLEGFAEAEKAYRTG
EEEEEECCCCCCCCCCCEEEECCCHHEEEEHHHHHHCCCCCCCCEEEECHHHHHHHHHCC
NAELHARVKVRITEVLRDENGIETRETKLVDTTVGRAMLWQIVPEGLPYSIINQKLGKKQ
CCEEEEEEEEEEHHHHHCCCCCCHHHHEEHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHH
ISNLLNEAYRTLGSKDTVIFADQIMYTGFAYAALSGASVGIDDMVIPDAKYTKVAEAEEE
HHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHH
VKQIQEQYQSGLVTAGERYNKVIDIWAATNEQVAKEMMDNLSSETVLNRDGEEEQQESFN
HHHHHHHHHCCCEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCHHHCCCCCHHHHHCCC
SVYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVNQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCHHHCCCCCCEEEEECCCCC
KGLADTALKTANSGYLTRRLVDVAQDVVVHLDDCGTLEGVTMMPLIEGGDVKEPLHERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCCHHHHHHHH
GRVVAEDVLKPGTDEILLPRNTLLDEKQCQIVEENSVDQIKVRSVVSCEADFGCCANCYG
HHHHHHHHHCCCCCCEEECCHHHCCCHHHHEECCCCCCCEEHHHHEECCCCCCCHHHHHH
RDLARGHMVNQGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASTAAADNSIQVKTTGSIKL
HHHHCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEEECCCEEE
HNAKHVTNNEGNLVITSRASQLTVIDGHGRTKESYKLSYGTILSKKDGDVVTQGDKIAAW
ECCCEEECCCCCEEEEECCCEEEEECCCCCCCCCEEEEEEEEEECCCCCEEECCCEEEEC
DPHTMPIITEVKGQVQFVDMIDGVTITTQTDELTGLSSIVILDTAERASAGKDMRPTVKL
CCCCCCEEEECCCCEEEEEECCCEEEEECCHHHCCCCEEEEEECHHHHCCCCCCCCEEEE
VDANGRDIMIPGTEMPAQYFLPGKAIVNLADGGDVGIGETLARIPQASSGTKDITGGLPR
EECCCCEEEECCCCCCHHHCCCCHHEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEHAGIVAFGKETKGKVRLLITRDDTGEVYEEMIHKHRQLNIFD
HHHHHHHCCCCCCCEEECCCCEEEECCCCCCEEEEEEEECCCHHHHHHHHHHHCEEEEEC
GDKVERGDVISDGPETPHDILRLRGIHAVTEYITNEVQEVYRLQGVKINDKHIETIVRQM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LRKCTITHSGDSTFLEGEQLEFANVTIANRQLEAEGKQPARFGRDLLGITKASLATESFI
HHHCCEEECCCCCEECCCCEEEEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVSGKRDELRGLKENVIVGRLIPAGTGFSYHQARQKQKAAAKVAP
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
SAEEATDNLAALLNAGFSSEE
CHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA