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The map label for this gene is rnr [H]

Identifier: 209696174

GI number: 209696174

Start: 2996572

End: 2999073

Strand: Reverse

Name: rnr [H]

Synonym: VSAL_I2768

Alternate gene names: 209696174

Gene position: 2999073-2996572 (Counterclockwise)

Preceding gene: 209696175

Following gene: 209696173

Centisome position: 90.19

GC content: 43.13

Gene sequence:

>2502_bases
ATGTCTAAGATTATTCAAAACGATCCTTTCAAAGATCGAGAAGCAGAAAAGTACGAGAATCCAATTCCAAGCCGTGAGTT
CATTCTTGAATTTTTCCAAAAAGCAGAAGCGCCTTTAAATCGTAATGACTTATTCGAAGCCCTAGGTTTATCTGGTGAAG
ATAACTATGAAGGCTTACGTCGTCGTTTAAGAGCAATGGAACGAGATGGGCAATTAGTCTTTACTCGTCGTCAGTGTTAC
GCGCTACCTGAACGTATTGAAGTATTGAAAGGCCTTGTTCTTGGTCACCGTGATGGCTTCGGTTGGATCCGTCCTGAAGG
CAGCATTGGTAAAGATAACGATGTGCTTTTGCCTTTCCACCAAATGAAAAAAGTCATTCATGGTGATGTGGTATTAGTGC
AACCAACGGGTACCGATAAACGAGGCCGAAAAGAAGGTCGTGTTATCCGTGTATTAGAGCCTCATAACGATGGCATTGTT
GGTCGATTCTTTACGGAAGATGGATTAAGTTTCGTTGTGCCTGACGATTCGCGTATTAACCAAGATATCTTCATTCCTAA
TGAGCATAAAATGAGTGCTCGTATGGGAAATGTTGTTGTGATTAATATCACTGACCGTGGTGGCCGTGCTCGCGGCATGT
CAGGTCATGTTATTGAAGTTCTTGGTGAGAATATGGCACCGGGAATGGAAATTGACATTGCACTTCGTACTCACAATATT
CCTCATGTATGGCCAGCAGCGGTTGAAAAACAAGTTGAAGGGCTAGCAGAGGAAGTGCCAGAAGAAGCAAAAGAAGGTCG
TGTCGATCTTCGTGAACTGCCATTAGTCACCATTGATGGTGAAGATGCTCGAGATTTCGATGATGCGGTATTCTGTCAAG
CAAAAGCCTCAGGTGGCTGGCGCTTATGGGTTGCGATTGCCGATGTTAGTTATTACGTTCGTCCAGAAAACGCATTAGAC
AAAGAAGCGATTCAGCGTGGTAATTCCGTTTACTTCCCTGCTCAAGTGGTTCCGATGTTACCGGAAATCTTGTCTAACGG
TTTATGTTCATTGAATCCTCAAGTTGACCGTTTATGTATGGTGTGTGAGATGACTATCTCTGCATCAGGAAAACTGTCAG
GCTTTAAACATTACGAAGCGGTGATGAACTCACACGCGCGTCTTACGTATAATAAAGTAAGCGACATTCTTGATGGTGAC
GAAGAGCTAACTCAACGTTATGAACCGTTGGTTCCGCACTTGAAAGAACTGCACAACATGTATCAGGTGCTAAAAACAGC
ACGTGAAGCGCGTGGTGCCATTGAATTTGAAACCATTGAAACTAAATTTATTTTCAATGCTGAACGTAAAATTGATCGCA
TCGAACCTGTGATCCGTAATGACGCACATAAAATCATCGAAGAATGTATGATTTTGGCGAATATCGCTTCAGCGACTTTT
GTAGAAAAAGCAAAAGAGCCAGCGTTGTACCGTGTGCATGAAGCGCCAGGTGAAGAACGCTTAACGGGTTTCCGTGATTT
CTTAGGAGAACTGGGTTTAAGCTTATCTGGTGGGTTAACGCCATCTCCAACAGATTACGGTCAATTAGTTCATTTGATTG
CCGATCGTCCAGATAAAGAATTGATTCAAACGATGTTACTGCGCTCAATGAAGCAAGCGGTATATAACGCAGATAATCAA
GGTCACTTTGGGTTGGCTCTTAAGCGTTATGCACACTTTACATCGCCAATTCGTCGTTACCCTGATTTATTATTGCATCG
TGCTATTAAGTATCTTATTGCAAAAGAAAAAGGTCATAACACCGATCGTTGGACACCAACAGGTGGGTATCATTATTCGT
TTGATGATATGGATGTGTTTGGTGAGCAATGTTCAATGACAGAGCGTCGTGCAGATGATGCGACACGTGATGTGTCTGAT
TGGTTGAAGTGTGAATACATGCAAGACCATATTGGCGAAGAACTAGAAGGTGTGATTGCCAATGTCACGGGCTTTGGTTT
CTTTGTTCGATTGAATGAGTTGCACATTGATGGTCTGGTACATATTTCATCTTTGGCAAATGACTATTACCAATTTGATG
CTGCGGGTCAGCGTTTAACGGGTGAGAGTTCAGGTCAGATCTTCCGATTGGGTGATCAAGTGACGGTGAAAGTACTTGCC
GTTAACTTAGATAGTCGCAACATTGACTTTGAATGCACTACCTCAATGCGTAAAGCGCGTGGTCAAGGCAAAACAGCCAA
AGACAATGCGAAGACGCGTGATGATAAAAAAGCCCCTCGCCGTGATCCTAATTTTAAAGCGAAAAAAGGCGATAAAGTTG
AACCGAAAGGTCGTGGTCAATTAGGTGAGCGTAAATCCAAAGGTAAGGGCAAAGTTAATTCAAAAGCTCAAGCCATGGTT
GAACCGACAAAGCGTCCTGACAGTTCTGCTGAAGGTGCTCCGGCGAATAAAAAACCAAGACACAAGAAAAAAGTACGCGC
AAGAAAGCCAAAGGCTGAGTAA

Upstream 100 bases:

>100_bases
ATTTTGTTAAAACGAGTGTAATTACTGATACTTTCCTATCTGTTGTTTCTATACTCAGGTACAATTACCTTATTATCTCC
TCTGACTAAGCAGGTCGCCT

Downstream 100 bases:

>100_bases
GTAAACATTCGATGATGAGGCAACGTTGCCTCATTAGCTCCACTAATTTGTAATAGAAAGAAGCGATAACATGAGTAATG
AATTTCTTTTTGGTATCCAC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 833; Mature: 832

Protein sequence:

>833_residues
MSKIIQNDPFKDREAEKYENPIPSREFILEFFQKAEAPLNRNDLFEALGLSGEDNYEGLRRRLRAMERDGQLVFTRRQCY
ALPERIEVLKGLVLGHRDGFGWIRPEGSIGKDNDVLLPFHQMKKVIHGDVVLVQPTGTDKRGRKEGRVIRVLEPHNDGIV
GRFFTEDGLSFVVPDDSRINQDIFIPNEHKMSARMGNVVVINITDRGGRARGMSGHVIEVLGENMAPGMEIDIALRTHNI
PHVWPAAVEKQVEGLAEEVPEEAKEGRVDLRELPLVTIDGEDARDFDDAVFCQAKASGGWRLWVAIADVSYYVRPENALD
KEAIQRGNSVYFPAQVVPMLPEILSNGLCSLNPQVDRLCMVCEMTISASGKLSGFKHYEAVMNSHARLTYNKVSDILDGD
EELTQRYEPLVPHLKELHNMYQVLKTAREARGAIEFETIETKFIFNAERKIDRIEPVIRNDAHKIIEECMILANIASATF
VEKAKEPALYRVHEAPGEERLTGFRDFLGELGLSLSGGLTPSPTDYGQLVHLIADRPDKELIQTMLLRSMKQAVYNADNQ
GHFGLALKRYAHFTSPIRRYPDLLLHRAIKYLIAKEKGHNTDRWTPTGGYHYSFDDMDVFGEQCSMTERRADDATRDVSD
WLKCEYMQDHIGEELEGVIANVTGFGFFVRLNELHIDGLVHISSLANDYYQFDAAGQRLTGESSGQIFRLGDQVTVKVLA
VNLDSRNIDFECTTSMRKARGQGKTAKDNAKTRDDKKAPRRDPNFKAKKGDKVEPKGRGQLGERKSKGKGKVNSKAQAMV
EPTKRPDSSAEGAPANKKPRHKKKVRARKPKAE

Sequences:

>Translated_833_residues
MSKIIQNDPFKDREAEKYENPIPSREFILEFFQKAEAPLNRNDLFEALGLSGEDNYEGLRRRLRAMERDGQLVFTRRQCY
ALPERIEVLKGLVLGHRDGFGWIRPEGSIGKDNDVLLPFHQMKKVIHGDVVLVQPTGTDKRGRKEGRVIRVLEPHNDGIV
GRFFTEDGLSFVVPDDSRINQDIFIPNEHKMSARMGNVVVINITDRGGRARGMSGHVIEVLGENMAPGMEIDIALRTHNI
PHVWPAAVEKQVEGLAEEVPEEAKEGRVDLRELPLVTIDGEDARDFDDAVFCQAKASGGWRLWVAIADVSYYVRPENALD
KEAIQRGNSVYFPAQVVPMLPEILSNGLCSLNPQVDRLCMVCEMTISASGKLSGFKHYEAVMNSHARLTYNKVSDILDGD
EELTQRYEPLVPHLKELHNMYQVLKTAREARGAIEFETIETKFIFNAERKIDRIEPVIRNDAHKIIEECMILANIASATF
VEKAKEPALYRVHEAPGEERLTGFRDFLGELGLSLSGGLTPSPTDYGQLVHLIADRPDKELIQTMLLRSMKQAVYNADNQ
GHFGLALKRYAHFTSPIRRYPDLLLHRAIKYLIAKEKGHNTDRWTPTGGYHYSFDDMDVFGEQCSMTERRADDATRDVSD
WLKCEYMQDHIGEELEGVIANVTGFGFFVRLNELHIDGLVHISSLANDYYQFDAAGQRLTGESSGQIFRLGDQVTVKVLA
VNLDSRNIDFECTTSMRKARGQGKTAKDNAKTRDDKKAPRRDPNFKAKKGDKVEPKGRGQLGERKSKGKGKVNSKAQAMV
EPTKRPDSSAEGAPANKKPRHKKKVRARKPKAE
>Mature_832_residues
SKIIQNDPFKDREAEKYENPIPSREFILEFFQKAEAPLNRNDLFEALGLSGEDNYEGLRRRLRAMERDGQLVFTRRQCYA
LPERIEVLKGLVLGHRDGFGWIRPEGSIGKDNDVLLPFHQMKKVIHGDVVLVQPTGTDKRGRKEGRVIRVLEPHNDGIVG
RFFTEDGLSFVVPDDSRINQDIFIPNEHKMSARMGNVVVINITDRGGRARGMSGHVIEVLGENMAPGMEIDIALRTHNIP
HVWPAAVEKQVEGLAEEVPEEAKEGRVDLRELPLVTIDGEDARDFDDAVFCQAKASGGWRLWVAIADVSYYVRPENALDK
EAIQRGNSVYFPAQVVPMLPEILSNGLCSLNPQVDRLCMVCEMTISASGKLSGFKHYEAVMNSHARLTYNKVSDILDGDE
ELTQRYEPLVPHLKELHNMYQVLKTAREARGAIEFETIETKFIFNAERKIDRIEPVIRNDAHKIIEECMILANIASATFV
EKAKEPALYRVHEAPGEERLTGFRDFLGELGLSLSGGLTPSPTDYGQLVHLIADRPDKELIQTMLLRSMKQAVYNADNQG
HFGLALKRYAHFTSPIRRYPDLLLHRAIKYLIAKEKGHNTDRWTPTGGYHYSFDDMDVFGEQCSMTERRADDATRDVSDW
LKCEYMQDHIGEELEGVIANVTGFGFFVRLNELHIDGLVHISSLANDYYQFDAAGQRLTGESSGQIFRLGDQVTVKVLAV
NLDSRNIDFECTTSMRKARGQGKTAKDNAKTRDDKKAPRRDPNFKAKKGDKVEPKGRGQLGERKSKGKGKVNSKAQAMVE
PTKRPDSSAEGAPANKKPRHKKKVRARKPKAE

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=483, Percent_Identity=29.8136645962733, Blast_Score=182, Evalue=9e-46,
Organism=Homo sapiens, GI190014625, Length=483, Percent_Identity=29.8136645962733, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI134288890, Length=362, Percent_Identity=33.1491712707182, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI19115966, Length=655, Percent_Identity=26.1068702290076, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI219521928, Length=708, Percent_Identity=26.1299435028249, Blast_Score=157, Evalue=3e-38,
Organism=Escherichia coli, GI87082383, Length=744, Percent_Identity=66.1290322580645, Blast_Score=1048, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=653, Percent_Identity=25.7274119448698, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17553506, Length=419, Percent_Identity=32.4582338902148, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI212645896, Length=409, Percent_Identity=31.0513447432763, Blast_Score=176, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6324552, Length=536, Percent_Identity=26.3059701492537, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24649634, Length=449, Percent_Identity=29.8440979955457, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI19922976, Length=369, Percent_Identity=28.7262872628726, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24654597, Length=369, Percent_Identity=28.7262872628726, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24654592, Length=369, Percent_Identity=28.7262872628726, Blast_Score=130, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 93954; Mature: 93823

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIQNDPFKDREAEKYENPIPSREFILEFFQKAEAPLNRNDLFEALGLSGEDNYEGLR
CCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHH
RRLRAMERDGQLVFTRRQCYALPERIEVLKGLVLGHRDGFGWIRPEGSIGKDNDVLLPFH
HHHHHHCCCCCEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEECHH
QMKKVIHGDVVLVQPTGTDKRGRKEGRVIRVLEPHNDGIVGRFFTEDGLSFVVPDDSRIN
HHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEECCCCCCC
QDIFIPNEHKMSARMGNVVVINITDRGGRARGMSGHVIEVLGENMAPGMEIDIALRTHNI
CCEECCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCC
PHVWPAAVEKQVEGLAEEVPEEAKEGRVDLRELPLVTIDGEDARDFDDAVFCQAKASGGW
CCCCHHHHHHHHHHHHHHCCHHHHCCCCCHHHCCEEEECCCCCCCCCCCEEEEEECCCCE
RLWVAIADVSYYVRPENALDKEAIQRGNSVYFPAQVVPMLPEILSNGLCSLNPQVDRLCM
EEEEEEECCEEEECCCCCCCHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCCCHHHHHHH
VCEMTISASGKLSGFKHYEAVMNSHARLTYNKVSDILDGDEELTQRYEPLVPHLKELHNM
HHHHHHCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
YQVLKTAREARGAIEFETIETKFIFNAERKIDRIEPVIRNDAHKIIEECMILANIASATF
HHHHHHHHHHCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEKAKEPALYRVHEAPGEERLTGFRDFLGELGLSLSGGLTPSPTDYGQLVHLIADRPDKE
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHH
LIQTMLLRSMKQAVYNADNQGHFGLALKRYAHFTSPIRRYPDLLLHRAIKYLIAKEKGHN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDRWTPTGGYHYSFDDMDVFGEQCSMTERRADDATRDVSDWLKCEYMQDHIGEELEGVIA
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
NVTGFGFFVRLNELHIDGLVHISSLANDYYQFDAAGQRLTGESSGQIFRLGDQVTVKVLA
HHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEE
VNLDSRNIDFECTTSMRKARGQGKTAKDNAKTRDDKKAPRRDPNFKAKKGDKVEPKGRGQ
EECCCCCCCEEECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LGERKSKGKGKVNSKAQAMVEPTKRPDSSAEGAPANKKPRHKKKVRARKPKAE
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SKIIQNDPFKDREAEKYENPIPSREFILEFFQKAEAPLNRNDLFEALGLSGEDNYEGLR
CCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHH
RRLRAMERDGQLVFTRRQCYALPERIEVLKGLVLGHRDGFGWIRPEGSIGKDNDVLLPFH
HHHHHHCCCCCEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEECHH
QMKKVIHGDVVLVQPTGTDKRGRKEGRVIRVLEPHNDGIVGRFFTEDGLSFVVPDDSRIN
HHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCEEEECCCCCCC
QDIFIPNEHKMSARMGNVVVINITDRGGRARGMSGHVIEVLGENMAPGMEIDIALRTHNI
CCEECCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCC
PHVWPAAVEKQVEGLAEEVPEEAKEGRVDLRELPLVTIDGEDARDFDDAVFCQAKASGGW
CCCCHHHHHHHHHHHHHHCCHHHHCCCCCHHHCCEEEECCCCCCCCCCCEEEEEECCCCE
RLWVAIADVSYYVRPENALDKEAIQRGNSVYFPAQVVPMLPEILSNGLCSLNPQVDRLCM
EEEEEEECCEEEECCCCCCCHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCCCHHHHHHH
VCEMTISASGKLSGFKHYEAVMNSHARLTYNKVSDILDGDEELTQRYEPLVPHLKELHNM
HHHHHHCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
YQVLKTAREARGAIEFETIETKFIFNAERKIDRIEPVIRNDAHKIIEECMILANIASATF
HHHHHHHHHHCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEKAKEPALYRVHEAPGEERLTGFRDFLGELGLSLSGGLTPSPTDYGQLVHLIADRPDKE
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCHHH
LIQTMLLRSMKQAVYNADNQGHFGLALKRYAHFTSPIRRYPDLLLHRAIKYLIAKEKGHN
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDRWTPTGGYHYSFDDMDVFGEQCSMTERRADDATRDVSDWLKCEYMQDHIGEELEGVIA
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHH
NVTGFGFFVRLNELHIDGLVHISSLANDYYQFDAAGQRLTGESSGQIFRLGDQVTVKVLA
HHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEEEEEEE
VNLDSRNIDFECTTSMRKARGQGKTAKDNAKTRDDKKAPRRDPNFKAKKGDKVEPKGRGQ
EECCCCCCCEEECHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LGERKSKGKGKVNSKAQAMVEPTKRPDSSAEGAPANKKPRHKKKVRARKPKAE
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]