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The map label for this gene is gcp

Identifier: 209696102

GI number: 209696102

Start: 2915221

End: 2916237

Strand: Reverse

Name: gcp

Synonym: VSAL_I2694

Alternate gene names: 209696102

Gene position: 2916237-2915221 (Counterclockwise)

Preceding gene: 209696110

Following gene: 209696100

Centisome position: 87.7

GC content: 43.17

Gene sequence:

>1017_bases
ATGCGAATTTTAGGTATTGAAACCTCGTGTGATGAAACGGGTGTGGCTATTTATGATGACGAAAAAGGGCTATTGGCTCA
TCAGCTGTACAGCCAAGTTAAGTTACACGCAGATTATGGTGGTGTAGTACCTGAATTAGCGTCTCGTGATCATGTTAAAA
AAACAATTCCACTGATTCAAGCGGCATTAAATGATGCTGGCATGACAAAAGATGATATTGATGGTATTGCGTATACCGCT
GGCCCTGGTTTGGTTGGTGCGTTATTGGTTGGTTCAACTATTGGTCGTAGCATTGCGTACGCATGGGATGTACCTGCGAT
TCCTGTTCATCATATGGAAGGACATTTATTGGCTCCAATGCTGGAAGATAATCCACCGGAGTTTCCGTTTGTTGCATTGC
TCGTGTCTGGCGGACATACGTTGATGGTTGAAGTTAAAGGCATTGGTGATTATCAAATTCTTGGAGAATCTGTGGATGAT
GCTGCGGGTGAAGCGTTTGATAAAACGGCAAAATTAATGGGATTAGATTACCCAGGTGGCCCACGACTTTCTAAATTAGC
GGAAGCGGGTGTGAAAGGTCGTTTTAAATTCCCTCGCCCAATGACTGATCGTCCGGGACTTGATTTTAGTTTTTCAGGAT
TAAAAACATTTGCTGCAAATACCATTCGAGCAAATGATGACGATGAACAGACTCGTGCAGATATTGCATTTGCTTTCCAA
GAAGCAGTGGCGGATACGTTAGCGATAAAGTGTCGTCGTGCTTTAAAACAAACAGGTATGAAGCGATTGGTGATGGCGGG
TGGTGTGAGTGCAAATACGTATCTTCGTCAGGAATTAGAAGCCATGATGAAGAAAATTGGTGGCGAGGTATTTTACCCTC
GAACTGAGTTTTGTACGGATAACGGTGCGATGATTGCTTATGCAGGAATGCAACGTTTGAAAAATGGCGAAACAACAGAT
TTGGCCGTTCAAGCTAAACCTCGTTGGCCGATAGATCAATTAGCACCGATTAAATAA

Upstream 100 bases:

>100_bases
ATTTCTTTGTTTATTTTAGCTATGCTAGTCATCTCCTTGCTTGAGCTAGCTTAGGGATGTAGGTAATATGGCGATAAATT
AACAGGTAACAGAGAAAAAT

Downstream 100 bases:

>100_bases
GAAAAGATCGACAGAGATCGTAATGGATCTTTTTTACGAAATAAAGAAGGGGGACTTATTAGTCCCTTTTTCTTTACCAA
ATTTTCTTTTCTTTTCCGGC

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIQAALNDAGMTKDDIDGIAYTA
GPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTLMVEVKGIGDYQILGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAEAGVKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRANDDDEQTRADIAFAFQ
EAVADTLAIKCRRALKQTGMKRLVMAGGVSANTYLRQELEAMMKKIGGEVFYPRTEFCTDNGAMIAYAGMQRLKNGETTD
LAVQAKPRWPIDQLAPIK

Sequences:

>Translated_338_residues
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIQAALNDAGMTKDDIDGIAYTA
GPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTLMVEVKGIGDYQILGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAEAGVKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRANDDDEQTRADIAFAFQ
EAVADTLAIKCRRALKQTGMKRLVMAGGVSANTYLRQELEAMMKKIGGEVFYPRTEFCTDNGAMIAYAGMQRLKNGETTD
LAVQAKPRWPIDQLAPIK
>Mature_338_residues
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIQAALNDAGMTKDDIDGIAYTA
GPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTLMVEVKGIGDYQILGESVDD
AAGEAFDKTAKLMGLDYPGGPRLSKLAEAGVKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRANDDDEQTRADIAFAFQ
EAVADTLAIKCRRALKQTGMKRLVMAGGVSANTYLRQELEAMMKKIGGEVFYPRTEFCTDNGAMIAYAGMQRLKNGETTD
LAVQAKPRWPIDQLAPIK

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=337, Percent_Identity=35.6083086053413, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI8923380, Length=321, Percent_Identity=32.0872274143302, Blast_Score=149, Evalue=3e-36,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=79.6407185628742, Blast_Score=560, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17557464, Length=330, Percent_Identity=31.8181818181818, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71995670, Length=342, Percent_Identity=32.7485380116959, Blast_Score=147, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6320099, Length=370, Percent_Identity=31.8918918918919, Blast_Score=176, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=28.448275862069, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=34.1176470588235, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357207, Length=330, Percent_Identity=29.0909090909091, Blast_Score=147, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_ALISL (B6EM15)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264032.1
- MEROPS:   M22.001
- GeneID:   6987883
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2694
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36514; Mature: 36514

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIQ
CEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALNDAGMTKDDIDGIAYTAGPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCH
LEDNPPEFPFVALLVSGGHTLMVEVKGIGDYQILGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHEECCCCCC
PRLSKLAEAGVKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRANDDDEQTRADIAFAFQ
CHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHCCEECCCCCHHHHHHHHHHHH
EAVADTLAIKCRRALKQTGMKRLVMAGGVSANTYLRQELEAMMKKIGGEVFYPRTEFCTD
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEECCCHHHCCC
NGAMIAYAGMQRLKNGETTDLAVQAKPRWPIDQLAPIK
CCCEEEHHHHHHHCCCCCCEEEEEECCCCCHHHCCCCC
>Mature Secondary Structure
MRILGIETSCDETGVAIYDDEKGLLAHQLYSQVKLHADYGGVVPELASRDHVKKTIPLIQ
CEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALNDAGMTKDDIDGIAYTAGPGLVGALLVGSTIGRSIAYAWDVPAIPVHHMEGHLLAPM
HHHHHCCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEECCH
LEDNPPEFPFVALLVSGGHTLMVEVKGIGDYQILGESVDDAAGEAFDKTAKLMGLDYPGG
HCCCCCCCCEEEEEEECCCEEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHEECCCCCC
PRLSKLAEAGVKGRFKFPRPMTDRPGLDFSFSGLKTFAANTIRANDDDEQTRADIAFAFQ
CHHHHHHHCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHCCEECCCCCHHHHHHHHHHHH
EAVADTLAIKCRRALKQTGMKRLVMAGGVSANTYLRQELEAMMKKIGGEVFYPRTEFCTD
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEECCCHHHCCC
NGAMIAYAGMQRLKNGETTDLAVQAKPRWPIDQLAPIK
CCCEEEHHHHHHHCCCCCCEEEEEECCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA