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The map label for this gene is pdhR [H]

Identifier: 209696035

GI number: 209696035

Start: 2842192

End: 2842962

Strand: Reverse

Name: pdhR [H]

Synonym: VSAL_I2626

Alternate gene names: 209696035

Gene position: 2842962-2842192 (Counterclockwise)

Preceding gene: 209696036

Following gene: 209696034

Centisome position: 85.5

GC content: 42.54

Gene sequence:

>771_bases
ATGGCATATCAAAGGATCCGTCAGCCAAAATTGTCCGATGCAATCGAACAAGAACTTGAACGGCTGATATTAGAAGGAAC
CCTTTCTCCGGGACAGAAGTTACCCGCAGAAAGAGAGTTAGCAAAACAATTTGATGTTTCTCGTCCTTCTGTGCGAGAGG
CAATACAACGTTTAGAAGCGAAGCATTTATTAACTCGCCGTCAAGGTGGTGGTACGTTTGTTAATAAAGGCTTGTGGCAA
AGCTTTTCAGAGCCGTTGCTCGATTTATTGGCAACACACCCTGAAACGCAATTTGACTTACTGGAATCGCGTCACGCGTT
AGAAGGTATTTCTGCTTATTACGCGGCTTTACGTGGTAATGAAGAAGATTTCAAACGGATTAAAGAGTCACATGAATTAA
TCCAACAAGCGCAACAGGATGGTGATTTAAAAGCAGAAGCCTCTGCGGTTATGCACTGTCTTATTACGGTCACTGAATCA
GCGCATAATGTGGTATTACTTCACATGGTGCGCAGTTTAGAGCCGTTGCTTGAGCAAAACGTATTACAAAACTTTACCTT
ATTAAATCGTCGCGAAGCGGTGGTTGAAAAGGTGAGAGCACATAGAGCAGAAATGGTAGAAGCGATTGTGTCAGGAAAGC
CTGAAGAGGCTCGTTTGGCATCTCATTCTCATCTTGCTTATATTGAAGAAACATTGTTGGAATTGACAAAAGAAGAGAGT
CGCCGAGAGTGCTCACTTCGTCGAATTCAACAAAGTAATGACATGAATTAA

Upstream 100 bases:

>100_bases
AAATTTCAGCTCAGTTAAAATTGGTATTACCAATTAATTAGAATGACGAATGACTCACGGTAAAGTGAGCGGTAATCAAC
TTAAATCAGGTTGAGCTACG

Downstream 100 bases:

>100_bases
TCTGATTCATTTCATTGTCACCCTATTTGAACCAACAAATAAAAGGATAGCTCGCATGTCTGACATGAAGCATGACGTTG
ATGCACTAGAAACTCAAGAT

Product: transcriptional regulator PdhR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MAYQRIRQPKLSDAIEQELERLILEGTLSPGQKLPAERELAKQFDVSRPSVREAIQRLEAKHLLTRRQGGGTFVNKGLWQ
SFSEPLLDLLATHPETQFDLLESRHALEGISAYYAALRGNEEDFKRIKESHELIQQAQQDGDLKAEASAVMHCLITVTES
AHNVVLLHMVRSLEPLLEQNVLQNFTLLNRREAVVEKVRAHRAEMVEAIVSGKPEEARLASHSHLAYIEETLLELTKEES
RRECSLRRIQQSNDMN

Sequences:

>Translated_256_residues
MAYQRIRQPKLSDAIEQELERLILEGTLSPGQKLPAERELAKQFDVSRPSVREAIQRLEAKHLLTRRQGGGTFVNKGLWQ
SFSEPLLDLLATHPETQFDLLESRHALEGISAYYAALRGNEEDFKRIKESHELIQQAQQDGDLKAEASAVMHCLITVTES
AHNVVLLHMVRSLEPLLEQNVLQNFTLLNRREAVVEKVRAHRAEMVEAIVSGKPEEARLASHSHLAYIEETLLELTKEES
RRECSLRRIQQSNDMN
>Mature_255_residues
AYQRIRQPKLSDAIEQELERLILEGTLSPGQKLPAERELAKQFDVSRPSVREAIQRLEAKHLLTRRQGGGTFVNKGLWQS
FSEPLLDLLATHPETQFDLLESRHALEGISAYYAALRGNEEDFKRIKESHELIQQAQQDGDLKAEASAVMHCLITVTESA
HNVVLLHMVRSLEPLLEQNVLQNFTLLNRREAVVEKVRAHRAEMVEAIVSGKPEEARLASHSHLAYIEETLLELTKEESR
RECSLRRIQQSNDMN

Specific function: Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786303, Length=234, Percent_Identity=68.8034188034188, Blast_Score=327, Evalue=4e-91,
Organism=Escherichia coli, GI1790032, Length=236, Percent_Identity=32.6271186440678, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1789353, Length=232, Percent_Identity=28.448275862069, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790780, Length=220, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29231; Mature: 29099

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQRIRQPKLSDAIEQELERLILEGTLSPGQKLPAERELAKQFDVSRPSVREAIQRLEA
CCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
KHLLTRRQGGGTFVNKGLWQSFSEPLLDLLATHPETQFDLLESRHALEGISAYYAALRGN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
EEDFKRIKESHELIQQAQQDGDLKAEASAVMHCLITVTESAHNVVLLHMVRSLEPLLEQN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VLQNFTLLNRREAVVEKVRAHRAEMVEAIVSGKPEEARLASHSHLAYIEETLLELTKEES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRECSLRRIQQSNDMN
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AYQRIRQPKLSDAIEQELERLILEGTLSPGQKLPAERELAKQFDVSRPSVREAIQRLEA
CHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHH
KHLLTRRQGGGTFVNKGLWQSFSEPLLDLLATHPETQFDLLESRHALEGISAYYAALRGN
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
EEDFKRIKESHELIQQAQQDGDLKAEASAVMHCLITVTESAHNVVLLHMVRSLEPLLEQN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VLQNFTLLNRREAVVEKVRAHRAEMVEAIVSGKPEEARLASHSHLAYIEETLLELTKEES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RRECSLRRIQQSNDMN
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]