Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 209695994

GI number: 209695994

Start: 2777237

End: 2778262

Strand: Direct

Name: appC [H]

Synonym: VSAL_I2578

Alternate gene names: 209695994

Gene position: 2777237-2778262 (Clockwise)

Preceding gene: 209695993

Following gene: 209695995

Centisome position: 83.52

GC content: 42.79

Gene sequence:

>1026_bases
ATGAAAAACTTAATTAAACTTCTTACTGGTAACTCTAAGTCACTGTTTGGTTTAGGTATCTTATTCACGTTTATCTTCGT
CGCTGTATTTGCTCCATTTTTGAGTGACCACGCACCAGATAAACGAACAGGTAATCCACATGAATACCCAAGCTTTGTTG
TCAATGCGGCTGAAAACAATCCTGATGGATGGGTTTCAGAAAATTTAGCCACTGACCGTCGTTCTTTATTAATGTCTAAA
AAAGCAGATCACGTAATGGGAACAACACGTATGGGACGTGATGTTTGGTCTCAGCTTGCTCATGGCGCTCGTGTATCACT
GGCGGTTGGTTTTGGTGCTGGTTTCGTGGTGTGTTTCTTAGCAACCGTAATTGGTATCTCTGCGGGTTATTTCGGCGGCA
AAGTCGATGATATCTTAACCGCAGCAATGAACATCATGCTGGTTATTCCACAATATCCATTACTGTTCGTTCTTGCTGCA
TTCATCGGTGAAGCGGGCCCCGTAACCATTACTTTGATTATTGGGTGTACGTCCTGGGCATGGGGCGCACGTGTTATTCG
AGCTCAAACCTTATCAATACGTGAAAAAGAATTTGTTAGAGCGGCAGAGGTTTTAGGTGAATCTTCATTGCGCATCATTT
TTGTTGAAATTCTTCCAAACCTTATTTCAATTGTAGGCGCAAGTTTCATTGGTTCAGTAATGTACGCCATCATGATGGAA
GCAACGATTTCATTCTTAGGTCTTGGTGATCCAAGTACCATTAGCTGGGGCATCATGCTGTACAACGTACAAACATCATC
ATCTATCCTAATTGGCGCATGGTGGGAGTTGATTGCACCTTGTATGGCTCTGACACTTCTCGCTGTCGGTCTTGCAATGC
TTAACTTCGCCGTTGATGAAATCGCTAACCCACAACTTCGTTCTCACAAAGGAATGAAACGTTGGAAAAAACTAGCCGCT
CAAGATACAAACGAGCGTAAACCAGACCTAGGTAAACCAGTATTAAATTGGAACAGGGAAGATTGA

Upstream 100 bases:

>100_bases
AGCTATTAATCATGACTCTGTTTATGCTCTTCTTTAACCTTCTTGCAGACATGTTATACGTTGTTCTAGACCCTCGCTTA
CGCAAGGGAGGAAAATAATA

Downstream 100 bases:

>100_bases
TATGACTGACCCGCAAATTTCTATCCGCAATCTGTGTGTGGATTACATTACTGAATCAGGTGATGTACGTGCTGTAAACA
ATGTGAGTTTTGACATTGGT

Product: ABC transoprter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKNLIKLLTGNSKSLFGLGILFTFIFVAVFAPFLSDHAPDKRTGNPHEYPSFVVNAAENNPDGWVSENLATDRRSLLMSK
KADHVMGTTRMGRDVWSQLAHGARVSLAVGFGAGFVVCFLATVIGISAGYFGGKVDDILTAAMNIMLVIPQYPLLFVLAA
FIGEAGPVTITLIIGCTSWAWGARVIRAQTLSIREKEFVRAAEVLGESSLRIIFVEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPSTISWGIMLYNVQTSSSILIGAWWELIAPCMALTLLAVGLAMLNFAVDEIANPQLRSHKGMKRWKKLAA
QDTNERKPDLGKPVLNWNRED

Sequences:

>Translated_341_residues
MKNLIKLLTGNSKSLFGLGILFTFIFVAVFAPFLSDHAPDKRTGNPHEYPSFVVNAAENNPDGWVSENLATDRRSLLMSK
KADHVMGTTRMGRDVWSQLAHGARVSLAVGFGAGFVVCFLATVIGISAGYFGGKVDDILTAAMNIMLVIPQYPLLFVLAA
FIGEAGPVTITLIIGCTSWAWGARVIRAQTLSIREKEFVRAAEVLGESSLRIIFVEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPSTISWGIMLYNVQTSSSILIGAWWELIAPCMALTLLAVGLAMLNFAVDEIANPQLRSHKGMKRWKKLAA
QDTNERKPDLGKPVLNWNRED
>Mature_341_residues
MKNLIKLLTGNSKSLFGLGILFTFIFVAVFAPFLSDHAPDKRTGNPHEYPSFVVNAAENNPDGWVSENLATDRRSLLMSK
KADHVMGTTRMGRDVWSQLAHGARVSLAVGFGAGFVVCFLATVIGISAGYFGGKVDDILTAAMNIMLVIPQYPLLFVLAA
FIGEAGPVTITLIIGCTSWAWGARVIRAQTLSIREKEFVRAAEVLGESSLRIIFVEILPNLISIVGASFIGSVMYAIMME
ATISFLGLGDPSTISWGIMLYNVQTSSSILIGAWWELIAPCMALTLLAVGLAMLNFAVDEIANPQLRSHKGMKRWKKLAA
QDTNERKPDLGKPVLNWNRED

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=308, Percent_Identity=28.2467532467532, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789889, Length=201, Percent_Identity=33.8308457711443, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787054, Length=226, Percent_Identity=27.4336283185841, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789964, Length=258, Percent_Identity=32.5581395348837, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787498, Length=227, Percent_Identity=34.3612334801762, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787549, Length=184, Percent_Identity=32.0652173913043, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788505, Length=210, Percent_Identity=28.0952380952381, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37138; Mature: 37138

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLIKLLTGNSKSLFGLGILFTFIFVAVFAPFLSDHAPDKRTGNPHEYPSFVVNAAENN
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEECCCCC
PDGWVSENLATDRRSLLMSKKADHVMGTTRMGRDVWSQLAHGARVSLAVGFGAGFVVCFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
ATVIGISAGYFGGKVDDILTAAMNIMLVIPQYPLLFVLAAFIGEAGPVTITLIIGCTSWA
HHHHHHHCCCCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCHH
WGARVIRAQTLSIREKEFVRAAEVLGESSLRIIFVEILPNLISIVGASFIGSVMYAIMME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATISFLGLGDPSTISWGIMLYNVQTSSSILIGAWWELIAPCMALTLLAVGLAMLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWKKLAAQDTNERKPDLGKPVLNWNRED
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNLIKLLTGNSKSLFGLGILFTFIFVAVFAPFLSDHAPDKRTGNPHEYPSFVVNAAENN
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHEEECCCCC
PDGWVSENLATDRRSLLMSKKADHVMGTTRMGRDVWSQLAHGARVSLAVGFGAGFVVCFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
ATVIGISAGYFGGKVDDILTAAMNIMLVIPQYPLLFVLAAFIGEAGPVTITLIIGCTSWA
HHHHHHHCCCCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCHH
WGARVIRAQTLSIREKEFVRAAEVLGESSLRIIFVEILPNLISIVGASFIGSVMYAIMME
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATISFLGLGDPSTISWGIMLYNVQTSSSILIGAWWELIAPCMALTLLAVGLAMLNFAVDE
HHHHHHCCCCCCCEEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IANPQLRSHKGMKRWKKLAAQDTNERKPDLGKPVLNWNRED
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]