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The map label for this gene is erpA

Identifier: 209695988

GI number: 209695988

Start: 2765930

End: 2766271

Strand: Reverse

Name: erpA

Synonym: VSAL_I2571

Alternate gene names: 209695988

Gene position: 2766271-2765930 (Counterclockwise)

Preceding gene: 209696002

Following gene: 209695987

Centisome position: 83.19

GC content: 36.55

Gene sequence:

>342_bases
ATGAGTGATGTATCTGTGCCGTTAACGTTTTCTGATGTTGCAGCAGCAAAAGTTAAAACGTTAATTGCAGAAGAAGAAAA
TCCAAATCTAAAACTGCGTGTTTATATTACAGGTGGTGGTTGTAGCGGTTTCCAATACGGATTTACTTTTGATGAAGAAG
TAAATGAAGGCGATATGACCCTTGTAAATGATGGTGTAACACTTGTTGTTGATCCAATGAGTTTACAATACTTAATTGGT
GGTATTGTTGATTATACTGAAGGCCTAGAAGGCTCTCGTTTTTTCATTAATAACCCTAATGCAACGACAACTTGTGGTTG
TGGTGCATCATTTAGCGTTTAA

Upstream 100 bases:

>100_bases
CGGTTGAAGAGGATGTTTGTATTGAATACTTGAATGAAACAGTCAGGTATTAGATAATCAGAATTAAAATAGAATTGGAA
ACCAATCTTGAGAGGTTTAA

Downstream 100 bases:

>100_bases
GATTTACTATAATATAGGTAAATGAATATTTTTTCGTTTACCTTATTCTCTGCTTTGTAAAACGACATAACTTACAGTAA
ATCAGGATGTATTACTGTTT

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MSDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEEVNEGDMTLVNDGVTLVVDPMSLQYLIG
GIVDYTEGLEGSRFFINNPNATTTCGCGASFSV

Sequences:

>Translated_113_residues
MSDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEEVNEGDMTLVNDGVTLVVDPMSLQYLIG
GIVDYTEGLEGSRFFINNPNATTTCGCGASFSV
>Mature_112_residues
SDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEEVNEGDMTLVNDGVTLVVDPMSLQYLIGG
IVDYTEGLEGSRFFINNPNATTTCGCGASFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=44.578313253012, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=31.1320754716981, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=77.4774774774775, Blast_Score=187, Evalue=1e-49,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=41.8181818181818, Blast_Score=71, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=37.037037037037, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=28.3185840707965, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=108, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=36.7924528301887, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=44.578313253012, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=34.5794392523364, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_ALISL (B6EL03)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263918.1
- ProteinModelPortal:   B6EL03
- GeneID:   6987824
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2571
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12033; Mature: 11901

Theoretical pI: Translated: 3.76; Mature: 3.76

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEEVNEGDMT
CCCCEEEEEEHHHHHHHHHEEEECCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEE
LVNDGVTLVVDPMSLQYLIGGIVDYTEGLEGSRFFINNPNATTTCGCGASFSV
EEECCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
SDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEEVNEGDMT
CCCEEEEEEHHHHHHHHHEEEECCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEE
LVNDGVTLVVDPMSLQYLIGGIVDYTEGLEGSRFFINNPNATTTCGCGASFSV
EEECCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA