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The map label for this gene is arcB [H]

Identifier: 209695978

GI number: 209695978

Start: 2741396

End: 2743762

Strand: Reverse

Name: arcB [H]

Synonym: VSAL_I2560

Alternate gene names: 209695978

Gene position: 2743762-2741396 (Counterclockwise)

Preceding gene: 209695986

Following gene: 209695977

Centisome position: 82.52

GC content: 36.71

Gene sequence:

>2367_bases
ATGAAGCAGTTAAAAATTCTTGCGCAGTTTTATGTCGATCTTATGGTTAGGCTTGGGATCGTCCGTTTTAGTCTCTTACT
TGCCATCGCTCTTGTTGCTTTAGCTGTCATTGTTCAAGTTGGAGTGACTCTCGTCTTGAGTGGTGAAGTTAATGATTTAG
ACATTGTACGATCTGTTTTTTTTGGTTTACTGATCACTCCTTGGGCTGTTTTCTTTTTATCAGTAGTCGTTGAACACTTA
GAAGATTCTCGTCAACGCTTATCTAAATTGGTTGGTAAATTAGAAGAAATGAGAACTCGTGATCTTGATTTAAATAAAAA
ATTAAAAGGTAACGTCAAAAAACTGAATCAAGAAATAGAAGAGCGAGAAAAAGCAGAAGAGGCTCGCCAAGAAGCGATGG
GGGATTTGGAAAATGAGGTCTTTCATCGAGAAAAAGCACAATTAGAATTAGCTGAGCAAACTGCGTTATTGCGATCTTAC
CTTGATACTTCCCCCGATATAATTTATTACCGTAATGAATTAGGTTTTTTCTCTGGCTGTAATAAAGCCATGGAGGATCT
CATCGGTAAATCTGAAAAAGAACTGATTGGATTATCACCTAAAGATGTTTATAGCATTGAAGTCGCGACTAAAGTCATTG
ATACCGATAGACAAGTTCTTAAAGAGAACCAAGCATTAACGTATGAACAGTGGCTTGATTATCCTGATGGCAGAAAAGCG
TGTTTTGAATTAAGCAAAATCCCTTTTTATAGTAAAGATGGTCGTCACTTAGGTTTGGTTGGTTTTGGACGAAACATAAC
GGATCGTAAAAGTTACGAAGAGGCCCTAGAAAAAGCCAGTCGTGACAAAACAACATTTATATCAACAATCAGTCATGAAT
TACGAACACCACTTAATGGTATTGTCGGATTAAGTCGTATGCTGCTTGATACCCGTCTTGATGATGAACAACATAATTAT
ATGCGAACTATTAATGTCAGTGCGATCACTTTGGGTAATATATTTAACGATATTATTGATATGGATAAATTTGATCGCCG
TAGATTAGAACTATTACCTAAGCCTCTTGATTTTATTAGTTTTGTTACTGAAATGGAAAATATATCAGGATTAATGGCAG
AGCAAAAAGGGCTGCGTTTTGATCTAGAAAGACTAACGAGCCTTCCCGCGCATATCTGTGTTGATAGTACTCGTTTACGA
CAAGTTCTTTGGAATTTAATCGGGAATGCGACTAAATTCACGAAAGAAGGCGGAGTTGTGATGTCCGTGAGTGCCGATAT
ACACGGTGACAATGCAGATATAACTTTTGAAGTGGAAGATTCAGGAATTGGGATCCCTGAGTCTGAATTAGAAAATGTGT
TTACTATGTATTATCAGGTGAAACAAGGCAAAGATAATTTACATGCAGTAGGGACTGGTATTGGTTTAGCGGTATCTAAA
GAATTAATTAACTTGATGGGAGGGGACATTACAGTAACCAGTGATGTCGGGTTTGGTAGTACGTTTATTGTCTCTATCAA
CGTCCCCTTGGTTGATCATGTTGAAGAAGAAGAAGCAATGCCTGAGATGAAAAGTGCAAAATCTTTGCGAATTTTTATGC
TTGAGGATATTGAACTGAATATTACCGTCGCTCGTTCGTTGCTTGAAAGTTTAGGTCATACCGTCGATGTGGCTATGTGT
GGTGAAGATGCAATCAATCAATTTGATCCCACAAACTATGATTTAGCGTTATTAGATATTCAATTACCTGACATGACTGG
ATTTGATGTCGCTCAAATATTTAGAGAAAAATATGAGGAATTACCACCGTTAGTTGCTTTAACGGCTAATTTATTAAAAG
AAAAAGACGAATACTTTGAAAAAGGTATGGATGAAGCCATCAGCAAACCGTTAAGTGTTAAAGCGTTAACTGAAGTACTT
GAACTGTTCTCTATCTCCGATGAAAAAGAGAGAGAGAAAGAAAATAAAGTGGCTCAAATTAAAACGGCAGAACAACTTGA
GAGTGAGCATTTAATTGATACTTTACTCGATTTAGAAATGCTTGAGTCGTACATCGAGATAGTTGGTACAAAACCTATTT
ATACCAGCATCGAAATGTTTGAAAGCAGTATGAAAGAATATATTCAAATACTTGATTCAAACATGACAGCACGAGATCAA
GATGGCATTGTATTTGAGACTCATAAAATGAAAGGGGCTGCGGGATCCATTGGTTTAAAGCATATTCAACAAGTGGCCCA
AAAAGCACAGTCTCCAGATTTACCAGCGTGGTGGGAGAATATTGATGATTGGGTTGAAGAAATTAAAAATGAATATGAAA
ATGATATTCAAGTACTAAAAAGTTGGTTAAAGCAGCGACAAAATTAA

Upstream 100 bases:

>100_bases
ATTAACACGCCTTTCAAATACACGATCCCAGTGTTGAAAAAATAACTCAAATAGAATGAACCCTGATATTATTCATATTG
AATATTATCAGGGTGTATCT

Downstream 100 bases:

>100_bases
GGAACTATAATGAAAAGAATAATGATAGTAACCGCAGTCATAATCGGACTTGCTGGTTGTCAGATGACTTCTGAAGACAA
CATCGATTGGCAACAAGATA

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIVRSVFFGLLITPWAVFFLSVVVEHL
EDSRQRLSKLVGKLEEMRTRDLDLNKKLKGNVKKLNQEIEEREKAEEARQEAMGDLENEVFHREKAQLELAEQTALLRSY
LDTSPDIIYYRNELGFFSGCNKAMEDLIGKSEKELIGLSPKDVYSIEVATKVIDTDRQVLKENQALTYEQWLDYPDGRKA
CFELSKIPFYSKDGRHLGLVGFGRNITDRKSYEEALEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTRLDDEQHNY
MRTINVSAITLGNIFNDIIDMDKFDRRRLELLPKPLDFISFVTEMENISGLMAEQKGLRFDLERLTSLPAHICVDSTRLR
QVLWNLIGNATKFTKEGGVVMSVSADIHGDNADITFEVEDSGIGIPESELENVFTMYYQVKQGKDNLHAVGTGIGLAVSK
ELINLMGGDITVTSDVGFGSTFIVSINVPLVDHVEEEEAMPEMKSAKSLRIFMLEDIELNITVARSLLESLGHTVDVAMC
GEDAINQFDPTNYDLALLDIQLPDMTGFDVAQIFREKYEELPPLVALTANLLKEKDEYFEKGMDEAISKPLSVKALTEVL
ELFSISDEKEREKENKVAQIKTAEQLESEHLIDTLLDLEMLESYIEIVGTKPIYTSIEMFESSMKEYIQILDSNMTARDQ
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYENDIQVLKSWLKQRQN

Sequences:

>Translated_788_residues
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIVRSVFFGLLITPWAVFFLSVVVEHL
EDSRQRLSKLVGKLEEMRTRDLDLNKKLKGNVKKLNQEIEEREKAEEARQEAMGDLENEVFHREKAQLELAEQTALLRSY
LDTSPDIIYYRNELGFFSGCNKAMEDLIGKSEKELIGLSPKDVYSIEVATKVIDTDRQVLKENQALTYEQWLDYPDGRKA
CFELSKIPFYSKDGRHLGLVGFGRNITDRKSYEEALEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTRLDDEQHNY
MRTINVSAITLGNIFNDIIDMDKFDRRRLELLPKPLDFISFVTEMENISGLMAEQKGLRFDLERLTSLPAHICVDSTRLR
QVLWNLIGNATKFTKEGGVVMSVSADIHGDNADITFEVEDSGIGIPESELENVFTMYYQVKQGKDNLHAVGTGIGLAVSK
ELINLMGGDITVTSDVGFGSTFIVSINVPLVDHVEEEEAMPEMKSAKSLRIFMLEDIELNITVARSLLESLGHTVDVAMC
GEDAINQFDPTNYDLALLDIQLPDMTGFDVAQIFREKYEELPPLVALTANLLKEKDEYFEKGMDEAISKPLSVKALTEVL
ELFSISDEKEREKENKVAQIKTAEQLESEHLIDTLLDLEMLESYIEIVGTKPIYTSIEMFESSMKEYIQILDSNMTARDQ
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYENDIQVLKSWLKQRQN
>Mature_788_residues
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIVRSVFFGLLITPWAVFFLSVVVEHL
EDSRQRLSKLVGKLEEMRTRDLDLNKKLKGNVKKLNQEIEEREKAEEARQEAMGDLENEVFHREKAQLELAEQTALLRSY
LDTSPDIIYYRNELGFFSGCNKAMEDLIGKSEKELIGLSPKDVYSIEVATKVIDTDRQVLKENQALTYEQWLDYPDGRKA
CFELSKIPFYSKDGRHLGLVGFGRNITDRKSYEEALEKASRDKTTFISTISHELRTPLNGIVGLSRMLLDTRLDDEQHNY
MRTINVSAITLGNIFNDIIDMDKFDRRRLELLPKPLDFISFVTEMENISGLMAEQKGLRFDLERLTSLPAHICVDSTRLR
QVLWNLIGNATKFTKEGGVVMSVSADIHGDNADITFEVEDSGIGIPESELENVFTMYYQVKQGKDNLHAVGTGIGLAVSK
ELINLMGGDITVTSDVGFGSTFIVSINVPLVDHVEEEEAMPEMKSAKSLRIFMLEDIELNITVARSLLESLGHTVDVAMC
GEDAINQFDPTNYDLALLDIQLPDMTGFDVAQIFREKYEELPPLVALTANLLKEKDEYFEKGMDEAISKPLSVKALTEVL
ELFSISDEKEREKENKVAQIKTAEQLESEHLIDTLLDLEMLESYIEIVGTKPIYTSIEMFESSMKEYIQILDSNMTARDQ
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYENDIQVLKSWLKQRQN

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=791, Percent_Identity=58.2806573957016, Blast_Score=919, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=527, Percent_Identity=29.4117647058824, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789149, Length=396, Percent_Identity=30.3030303030303, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI87081816, Length=534, Percent_Identity=25.8426966292135, Blast_Score=156, Evalue=5e-39,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=37.1308016877637, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=29.7297297297297, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=385, Percent_Identity=24.4155844155844, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=261, Percent_Identity=26.8199233716475, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=258, Percent_Identity=25.1937984496124, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786600, Length=361, Percent_Identity=23.2686980609418, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=329, Percent_Identity=24.6200607902736, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=22.2222222222222, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89327; Mature: 89327

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIVRSVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCHHHHHHHHH
FGLLITPWAVFFLSVVVEHLEDSRQRLSKLVGKLEEMRTRDLDLNKKLKGNVKKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHH
EREKAEEARQEAMGDLENEVFHREKAQLELAEQTALLRSYLDTSPDIIYYRNELGFFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
NKAMEDLIGKSEKELIGLSPKDVYSIEVATKVIDTDRQVLKENQALTYEQWLDYPDGRKA
HHHHHHHHCCCCHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCHHH
CFELSKIPFYSKDGRHLGLVGFGRNITDRKSYEEALEKASRDKTTFISTISHELRTPLNG
HHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDTRLDDEQHNYMRTINVSAITLGNIFNDIIDMDKFDRRRLELLPKPLDFIS
HHHHHHHHHHHCCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FVTEMENISGLMAEQKGLRFDLERLTSLPAHICVDSTRLRQVLWNLIGNATKFTKEGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHHCCCHHHHCCHHHHHHHHHHHHCCCHHEECCCCEE
MSVSADIHGDNADITFEVEDSGIGIPESELENVFTMYYQVKQGKDNLHAVGTGIGLAVSK
EEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHH
ELINLMGGDITVTSDVGFGSTFIVSINVPLVDHVEEEEAMPEMKSAKSLRIFMLEDIELN
HHHHHCCCCEEEEECCCCCCEEEEEECCCHHHCCCHHHHCCHHHCCCCEEEEEEECCEEH
ITVARSLLESLGHTVDVAMCGEDAINQFDPTNYDLALLDIQLPDMTGFDVAQIFREKYEE
HHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
LPPLVALTANLLKEKDEYFEKGMDEAISKPLSVKALTEVLELFSISDEKEREKENKVAQI
CCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KTAEQLESEHLIDTLLDLEMLESYIEIVGTKPIYTSIEMFESSMKEYIQILDSNMTARDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYENDIQVLK
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SWLKQRQN
HHHHHHCC
>Mature Secondary Structure
MKQLKILAQFYVDLMVRLGIVRFSLLLAIALVALAVIVQVGVTLVLSGEVNDLDIVRSVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCHHHHHHHHH
FGLLITPWAVFFLSVVVEHLEDSRQRLSKLVGKLEEMRTRDLDLNKKLKGNVKKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHH
EREKAEEARQEAMGDLENEVFHREKAQLELAEQTALLRSYLDTSPDIIYYRNELGFFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
NKAMEDLIGKSEKELIGLSPKDVYSIEVATKVIDTDRQVLKENQALTYEQWLDYPDGRKA
HHHHHHHHCCCCHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCHHH
CFELSKIPFYSKDGRHLGLVGFGRNITDRKSYEEALEKASRDKTTFISTISHELRTPLNG
HHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRMLLDTRLDDEQHNYMRTINVSAITLGNIFNDIIDMDKFDRRRLELLPKPLDFIS
HHHHHHHHHHHCCCCCHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FVTEMENISGLMAEQKGLRFDLERLTSLPAHICVDSTRLRQVLWNLIGNATKFTKEGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHHCCCHHHHCCHHHHHHHHHHHHCCCHHEECCCCEE
MSVSADIHGDNADITFEVEDSGIGIPESELENVFTMYYQVKQGKDNLHAVGTGIGLAVSK
EEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHH
ELINLMGGDITVTSDVGFGSTFIVSINVPLVDHVEEEEAMPEMKSAKSLRIFMLEDIELN
HHHHHCCCCEEEEECCCCCCEEEEEECCCHHHCCCHHHHCCHHHCCCCEEEEEEECCEEH
ITVARSLLESLGHTVDVAMCGEDAINQFDPTNYDLALLDIQLPDMTGFDVAQIFREKYEE
HHHHHHHHHHCCCEEEEEECCHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
LPPLVALTANLLKEKDEYFEKGMDEAISKPLSVKALTEVLELFSISDEKEREKENKVAQI
CCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KTAEQLESEHLIDTLLDLEMLESYIEIVGTKPIYTSIEMFESSMKEYIQILDSNMTARDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DGIVFETHKMKGAAGSIGLKHIQQVAQKAQSPDLPAWWENIDDWVEEIKNEYENDIQVLK
CCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SWLKQRQN
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]