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The map label for this gene is metA [H]

Identifier: 209695917

GI number: 209695917

Start: 2678218

End: 2679156

Strand: Direct

Name: metA [H]

Synonym: VSAL_I2499

Alternate gene names: 209695917

Gene position: 2678218-2679156 (Clockwise)

Preceding gene: 209695916

Following gene: 209695918

Centisome position: 80.54

GC content: 39.51

Gene sequence:

>939_bases
GTGCCAATTAGAATCCCTGACCAACTCCCTGCTGCTGAAGTATTGCGTGAAGAAAATATCTTTGTCATGCAAGAATCTCG
AGCCACCACACAAGCCATTCGTCCTCTTAAAGTGATCATATTAAATTTGATGCCTAAGAAGATAGAAACAGAAACTCAAT
TTCTTCGCTTGTTATCAAACAGTCCACTACAAGTGGATGTTGAGCTATTACGCATTGATAATCGCACCAGTAAAAATACC
CCGACCGAACATTTAGATACTTTTTATCGCCAATTTGAAGGCATTAAAAATCGTAATTTTGATGGATTGATAATTACTGG
CGCTCCATTGGGTTTAGTCCAATTTGAAGATGTTATTTATTGGGAGCACTTACAAACCATCATGACGTGGGCAAAGGATC
ATGTCACATCGAGTTTGTATGTTTGTTGGGCGGCACAAGCCGGTTTAAAATTGCTGTATGATTTACCAAAACGCACACGC
AAAGAAAAACTGTCTGGTGTTTACAAACACACCAACCTTGAACAACATCACCCCATTTTACGTGGTTTTGATGATCAATT
TTTAGCGCCTCATTCTCATTATGCGGATTTTTCTGCCGATTATCTTAACGCTCATACCGATCTCGACATCCTTGCTACCT
CAAAAGAAGCCGGGGTTTATTTAGCATCAACCAAAGACAAGCGAAATGTATTTGTTACTGGTCACCCTGAATACGACTCT
CTCACTTTACATAATGAATATCTTCGTGATTTAGGTGAAGGAATGGAACCTATTATTCCGGTTAATTATTACCCTGATGA
TAACCCTGATATTCCACCAAAAGCGACGTGGCGTAGTCACGGACATTTGTTGTTTTCTAATTGGTTGAATTACTGTGTTT
ACCAACAAACACCGTATGATCTTGACCATTTTTCAGAGCTCAACTTCACCCGCGATTAA

Upstream 100 bases:

>100_bases
TTAGTGCCCTTTCTTGTGTCGACACCCTATTCATATTAAGGTAGTTTAGGAGTATAGACGTATAGAATGCTATGAATTAA
AAATAACTTAAGGATAAGTT

Downstream 100 bases:

>100_bases
CTCCTCACTAGGGCGTAATACATCAATTACGCCCTCCTAATAATAAAACCACCTAGATTTATCTGATAGATAGCCCACAC
TTTTTTATTTCGATCAAAAA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPIRIPDQLPAAEVLREENIFVMQESRATTQAIRPLKVIILNLMPKKIETETQFLRLLSNSPLQVDVELLRIDNRTSKNT
PTEHLDTFYRQFEGIKNRNFDGLIITGAPLGLVQFEDVIYWEHLQTIMTWAKDHVTSSLYVCWAAQAGLKLLYDLPKRTR
KEKLSGVYKHTNLEQHHPILRGFDDQFLAPHSHYADFSADYLNAHTDLDILATSKEAGVYLASTKDKRNVFVTGHPEYDS
LTLHNEYLRDLGEGMEPIIPVNYYPDDNPDIPPKATWRSHGHLLFSNWLNYCVYQQTPYDLDHFSELNFTRD

Sequences:

>Translated_312_residues
MPIRIPDQLPAAEVLREENIFVMQESRATTQAIRPLKVIILNLMPKKIETETQFLRLLSNSPLQVDVELLRIDNRTSKNT
PTEHLDTFYRQFEGIKNRNFDGLIITGAPLGLVQFEDVIYWEHLQTIMTWAKDHVTSSLYVCWAAQAGLKLLYDLPKRTR
KEKLSGVYKHTNLEQHHPILRGFDDQFLAPHSHYADFSADYLNAHTDLDILATSKEAGVYLASTKDKRNVFVTGHPEYDS
LTLHNEYLRDLGEGMEPIIPVNYYPDDNPDIPPKATWRSHGHLLFSNWLNYCVYQQTPYDLDHFSELNFTRD
>Mature_311_residues
PIRIPDQLPAAEVLREENIFVMQESRATTQAIRPLKVIILNLMPKKIETETQFLRLLSNSPLQVDVELLRIDNRTSKNTP
TEHLDTFYRQFEGIKNRNFDGLIITGAPLGLVQFEDVIYWEHLQTIMTWAKDHVTSSLYVCWAAQAGLKLLYDLPKRTRK
EKLSGVYKHTNLEQHHPILRGFDDQFLAPHSHYADFSADYLNAHTDLDILATSKEAGVYLASTKDKRNVFVTGHPEYDSL
TLHNEYLRDLGEGMEPIIPVNYYPDDNPDIPPKATWRSHGHLLFSNWLNYCVYQQTPYDLDHFSELNFTRD

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=305, Percent_Identity=63.9344262295082, Blast_Score=423, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36198; Mature: 36067

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRIPDQLPAAEVLREENIFVMQESRATTQAIRPLKVIILNLMPKKIETETQFLRLLSN
CCCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
SPLQVDVELLRIDNRTSKNTPTEHLDTFYRQFEGIKNRNFDGLIITGAPLGLVQFEDVIY
CCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHH
WEHLQTIMTWAKDHVTSSLYVCWAAQAGLKLLYDLPKRTRKEKLSGVYKHTNLEQHHPIL
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHH
RGFDDQFLAPHSHYADFSADYLNAHTDLDILATSKEAGVYLASTKDKRNVFVTGHPEYDS
HCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCCCCCC
LTLHNEYLRDLGEGMEPIIPVNYYPDDNPDIPPKATWRSHGHLLFSNWLNYCVYQQTPYD
EEECHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHEEECCCCCC
LDHFSELNFTRD
HHHHHCCCCCCC
>Mature Secondary Structure 
PIRIPDQLPAAEVLREENIFVMQESRATTQAIRPLKVIILNLMPKKIETETQFLRLLSN
CCCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
SPLQVDVELLRIDNRTSKNTPTEHLDTFYRQFEGIKNRNFDGLIITGAPLGLVQFEDVIY
CCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHH
WEHLQTIMTWAKDHVTSSLYVCWAAQAGLKLLYDLPKRTRKEKLSGVYKHTNLEQHHPIL
HHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHH
RGFDDQFLAPHSHYADFSADYLNAHTDLDILATSKEAGVYLASTKDKRNVFVTGHPEYDS
HCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEEECCCCCEEEEECCCCCEEEEECCCCCCC
LTLHNEYLRDLGEGMEPIIPVNYYPDDNPDIPPKATWRSHGHLLFSNWLNYCVYQQTPYD
EEECHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHEEECCCCCC
LDHFSELNFTRD
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA