Click here to switch to the map view.

The map label for this gene is flhA [H]

Identifier: 209695725

GI number: 209695725

Start: 2466352

End: 2468445

Strand: Reverse

Name: flhA [H]

Synonym: VSAL_I2293

Alternate gene names: 209695725

Gene position: 2468445-2466352 (Counterclockwise)

Preceding gene: 209695727

Following gene: 209695724

Centisome position: 74.24

GC content: 42.22

Gene sequence:

>2094_bases
ATGAAATTTCAAATTCCACTACCGAATAAACTCTCTGCCTTAAAAGGCAAGAAAATCCCATCAATAGGTGCGCCGATTTT
AGTGCTATCAGCACTAGCGATGGTGATATTACCGATCCCGGCTTTTTTACTCGATCTTATGTTTACGTTCAATATCGCCT
TAGCAATGGTTGTATTGTTAGTGACAATCTACACTCGTAGACCTCTTGATTTTGCTGCGTTCCCAACCATTCTTCTTGTA
TCTACCTTACTTCGCCTTGCTTTGAACGTGGCATCGACTCGTGTGGTATTGCTGCATGGTCATGAAGGGCCGGGAGCGGC
AGGTAACGTTATCGAGGCGTTTGGTAATGTGGTTATCGGCGGTAACTATGCGGTTGGTTTGATTGTTTTTATTATCTTGA
TGATCATTAACTTTATGGTTGTAACCAAAGGTGCGGGCCGTATTTCAGAAGTAAGTGCACGTTTCACCTTGGATGCCTTA
CCAGGTAAACAAATGGCGATTGATGCGGATTTGAATGCCGGCTTAATCGATCAAGAACAAGCAAGAACACGTCGTTTTGA
AGTCACCAAAGAAGCTGACTTTTACGGTTCAATGGATGGCGCGTCAAAATTTGTAAAAGGGGATGCCATTGCTGGTATCT
TAATTCTATTTATTAATATTATTGGTGGCTTTGCCATCGGTATGGCGCAATTTGATTTAGGTTTTAGTGAAGCGATTCAA
ATTTATACTTTGCTAACGATTGGTGATGGCTTGGTTGCTCAAATCCCATCATTACTATTGTCGATTGGTGCTGCGATCAT
GGTAACTCGTCAAAACACAGACGAAGACATGGGCGAGCAATTGGTGTTTCAATTAGTTGATAACCCAAAAGCATTGATGG
TAACGGGTGGGATCATGTTTATCATGGGTATTGTTCCTGGAATGCCTCATTTTCCATTTATATTGCTTGCGATTCTGGCG
AGTGGTTGGGCGTATTACCTAACGAAGAAAAAAGCACAAGAGGGAGAAGATAAAAAAGCAGCACCTCCAATGGAGTTGTC
TTCTTCACAACCTAAAGAACTGTCATGGGATGATGTTCAACCTGTCGATGTGATTGGATTAGAAGTTGGTTATCGTTTGA
TCCCAATGGTAGATAAAGAACAAGGTGGCGAGCTTCTTGACCGTGTTAAAGGGGTTCGTAAGAAGCTGTCTCAAGATTTC
GGTTTCTTGGTACCTGCGGTTCATATTCGAGATAATTTAGAACTGCCACCAAACGTATACAGAATTACCTTGATGGGTGT
GGCCGGTGGCGAAGCTGAAATTCGTCCAGATAAAGAATTAGCGATTAACCCAGGGCAAGTGTATGGCTCGATTGAAGGTG
AACCAACGCTTGATCCAGCCTTTGGTCTTGAAGCCGTATGGATAAACGAAGAGCAAAGAGAGCATGCTCAAGCCTTAGGC
TATACTGTTGTAGATGCTGCAACGGTATTAGCAACCCATTTAAGTCAATTGTTAACAAATAATGCGGCGCAGTTATTAGG
ACATGAAGAAGTTCAGAACTTATTAGAGTTGCTCTCACAAAGCTCACCTAAATTAGTTGAAGGGTTAGTACCCGATCAAT
TACCGTTAGGGGCGGTTGTAAAAGTACTTCAGAATTTATTGAATGAAGCAATTCCAGTTCGTGATATTAGAACCATTGTC
CAAACTTTGTCTGAATATGCGCCAAAAAGTCAAGAACCCGACATTTTGACGGCCGCCGTCAGAATTGCGCTAAAACGACT
AATTGTTCAGGAAATCAATGGGGTAGAGGCTGAAATGCCTGTTATTACCTTAATCCCAGAACTGGAACAAATTTTGCATC
AAACTATGCAGGCGTCAGGCGGTGAAACAACGGGCATTGAACCTGGTTTGGCTGAACGCTTGCAAGCTTCATTAACGCTT
GCGACTCAAGAACAAGAGTTAAAAGGAGAGGCCGCTGTCTTGCTGACATCGGGGGTGTTGCGTTCAACATTAGCGAAATT
TGTTAAGAATACAATTCCAAATTTACGAGTGCTTTCTTATCAAGAAATTCCAGATGAGAAGCAAATTAGAATAGTTCAAG
CCGTTGGTCATTAA

Upstream 100 bases:

>100_bases
TAATCTGGCTCGAAAATTGCTTTGTTAGATGTAGCCGTAAATGATCAGACTAAGATTATTAATTTTTATTAGTAATAACA
ATGAGTAAGAAGCCTAAGTG

Downstream 100 bases:

>100_bases
TCGCGTCGACTTATTTAACGCAGGAATACGAAATTGAAAATTAAACGATTTTTTGCAAAAGATATGCGCTCAGCTCTAGT
TCAAGTAAAAGAAGAACTGG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MKFQIPLPNKLSALKGKKIPSIGAPILVLSALAMVILPIPAFLLDLMFTFNIALAMVVLLVTIYTRRPLDFAAFPTILLV
STLLRLALNVASTRVVLLHGHEGPGAAGNVIEAFGNVVIGGNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQEQARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGFAIGMAQFDLGFSEAIQ
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTGGIMFIMGIVPGMPHFPFILLAILA
SGWAYYLTKKKAQEGEDKKAAPPMELSSSQPKELSWDDVQPVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDF
GFLVPAVHIRDNLELPPNVYRITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTLDPAFGLEAVWINEEQREHAQALG
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLSQSSPKLVEGLVPDQLPLGAVVKVLQNLLNEAIPVRDIRTIV
QTLSEYAPKSQEPDILTAAVRIALKRLIVQEINGVEAEMPVITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTL
ATQEQELKGEAAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGH

Sequences:

>Translated_697_residues
MKFQIPLPNKLSALKGKKIPSIGAPILVLSALAMVILPIPAFLLDLMFTFNIALAMVVLLVTIYTRRPLDFAAFPTILLV
STLLRLALNVASTRVVLLHGHEGPGAAGNVIEAFGNVVIGGNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQEQARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGFAIGMAQFDLGFSEAIQ
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTGGIMFIMGIVPGMPHFPFILLAILA
SGWAYYLTKKKAQEGEDKKAAPPMELSSSQPKELSWDDVQPVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDF
GFLVPAVHIRDNLELPPNVYRITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTLDPAFGLEAVWINEEQREHAQALG
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLSQSSPKLVEGLVPDQLPLGAVVKVLQNLLNEAIPVRDIRTIV
QTLSEYAPKSQEPDILTAAVRIALKRLIVQEINGVEAEMPVITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTL
ATQEQELKGEAAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGH
>Mature_697_residues
MKFQIPLPNKLSALKGKKIPSIGAPILVLSALAMVILPIPAFLLDLMFTFNIALAMVVLLVTIYTRRPLDFAAFPTILLV
STLLRLALNVASTRVVLLHGHEGPGAAGNVIEAFGNVVIGGNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQEQARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGFAIGMAQFDLGFSEAIQ
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTGGIMFIMGIVPGMPHFPFILLAILA
SGWAYYLTKKKAQEGEDKKAAPPMELSSSQPKELSWDDVQPVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDF
GFLVPAVHIRDNLELPPNVYRITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTLDPAFGLEAVWINEEQREHAQALG
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLSQSSPKLVEGLVPDQLPLGAVVKVLQNLLNEAIPVRDIRTIV
QTLSEYAPKSQEPDILTAAVRIALKRLIVQEINGVEAEMPVITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTL
ATQEQELKGEAAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGH

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=684, Percent_Identity=52.6315789473684, Blast_Score=699, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75367; Mature: 75367

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFQIPLPNKLSALKGKKIPSIGAPILVLSALAMVILPIPAFLLDLMFTFNIALAMVVLL
CEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIYTRRPLDFAAFPTILLVSTLLRLALNVASTRVVLLHGHEGPGAAGNVIEAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHCCEEEC
GNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHH
ARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGFAIGMAQFDLGFSEAIQ
HHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTGGIMF
HHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECHHHH
IMGIVPGMPHFPFILLAILASGWAYYLTKKKAQEGEDKKAAPPMELSSSQPKELSWDDVQ
HHHHCCCCCHHHHHHHHHHHCCHHEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDFGFLVPAVHIRDNLELPPNVY
CHHEEEHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEE
RITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTLDPAFGLEAVWINEEQREHAQALG
EEEEEEECCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHC
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLSQSSPKLVEGLVPDQLPLGAVV
HHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHH
KVLQNLLNEAIPVRDIRTIVQTLSEYAPKSQEPDILTAAVRIALKRLIVQEINGVEAEMP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
VITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTLATQEQELKGEAAVLLTSGVL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHEECCHHHHCCCCEEEHHHHHH
RSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGH
HHHHHHHHHHCCCCCEEEEHHCCCCHHHEEEEEECCC
>Mature Secondary Structure
MKFQIPLPNKLSALKGKKIPSIGAPILVLSALAMVILPIPAFLLDLMFTFNIALAMVVLL
CEEECCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTIYTRRPLDFAAFPTILLVSTLLRLALNVASTRVVLLHGHEGPGAAGNVIEAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHCCEEEC
GNYAVGLIVFIILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHH
ARTRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGFAIGMAQFDLGFSEAIQ
HHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGEQLVFQLVDNPKALMVTGGIMF
HHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECHHHH
IMGIVPGMPHFPFILLAILASGWAYYLTKKKAQEGEDKKAAPPMELSSSQPKELSWDDVQ
HHHHCCCCCHHHHHHHHHHHCCHHEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVDVIGLEVGYRLIPMVDKEQGGELLDRVKGVRKKLSQDFGFLVPAVHIRDNLELPPNVY
CHHEEEHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEE
RITLMGVAGGEAEIRPDKELAINPGQVYGSIEGEPTLDPAFGLEAVWINEEQREHAQALG
EEEEEEECCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHC
YTVVDAATVLATHLSQLLTNNAAQLLGHEEVQNLLELLSQSSPKLVEGLVPDQLPLGAVV
HHHHHHHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHH
KVLQNLLNEAIPVRDIRTIVQTLSEYAPKSQEPDILTAAVRIALKRLIVQEINGVEAEMP
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
VITLIPELEQILHQTMQASGGETTGIEPGLAERLQASLTLATQEQELKGEAAVLLTSGVL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHEECCHHHHCCCCEEEHHHHHH
RSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGH
HHHHHHHHHHCCCCCEEEEHHCCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]