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The map label for this gene is ccmE [H]

Identifier: 209695709

GI number: 209695709

Start: 2452835

End: 2453275

Strand: Reverse

Name: ccmE [H]

Synonym: VSAL_I2277

Alternate gene names: 209695709

Gene position: 2453275-2452835 (Counterclockwise)

Preceding gene: 209695710

Following gene: 209695708

Centisome position: 73.78

GC content: 42.86

Gene sequence:

>441_bases
ATGAATCCAAGACGTAAAAAGCGCCTAGGGTTGATCCTTGCTCTAGTCCTAGGGGCGAGTGCAACGGTTGGGTTGATGCT
TTATGCATTGAATCAAAATATGGATTTATTCTATACCCCAACAGAATTAGTGAATGGTAAGCCTGATGGAACAAAACCTG
AAGTCGGCCAACGTTTACGTATCGGTGGTATGGTTGTTGTAGGATCGGTTAAACGTGATTCTCAGTCTTTAGAAGTTCGT
TTTCAAGTCGAAGACATTGGCCCTAAAGTCACCGTTATTTATGATGGTATTCTTCCTGATTTATTCCGTGAAGGCCAAGG
TATTGTCGCGCAAGGTGTTCTTGTTGATGCGACAACAGTTAAGGCTCATGAAGTATTAGCGAAACATGATGAAGAGTACA
TGCCGCCAGAGGTTGCAGAAGCGATGAAAAAAACGCACTAA

Upstream 100 bases:

>100_bases
TTTCTAGCCTTGGAAAACGACGCCAATTATTAAAAGAAATTGAGCAAAGAATGGCAAGAGAAGAACGAATTAAAAAAGCA
AAAACTATGGAGAATACATT

Downstream 100 bases:

>100_bases
CCTCTTAAATACACAGAAGAACAAAAACAAGGAACTGGTCAATGATTCCAGAACTCGGTCATTTTGCGATGATTGCCTCA
TTAGGACTTGCTGTCCTATT

Product: cytochrome C biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MNPRRKKRLGLILALVLGASATVGLMLYALNQNMDLFYTPTELVNGKPDGTKPEVGQRLRIGGMVVVGSVKRDSQSLEVR
FQVEDIGPKVTVIYDGILPDLFREGQGIVAQGVLVDATTVKAHEVLAKHDEEYMPPEVAEAMKKTH

Sequences:

>Translated_146_residues
MNPRRKKRLGLILALVLGASATVGLMLYALNQNMDLFYTPTELVNGKPDGTKPEVGQRLRIGGMVVVGSVKRDSQSLEVR
FQVEDIGPKVTVIYDGILPDLFREGQGIVAQGVLVDATTVKAHEVLAKHDEEYMPPEVAEAMKKTH
>Mature_146_residues
MNPRRKKRLGLILALVLGASATVGLMLYALNQNMDLFYTPTELVNGKPDGTKPEVGQRLRIGGMVVVGSVKRDSQSLEVR
FQVEDIGPKVTVIYDGILPDLFREGQGIVAQGVLVDATTVKAHEVLAKHDEEYMPPEVAEAMKKTH

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=147, Percent_Identity=57.1428571428571, Blast_Score=166, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 15997; Mature: 15997

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRRKKRLGLILALVLGASATVGLMLYALNQNMDLFYTPTELVNGKPDGTKPEVGQRLR
CCCHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCEEEECCHHHHCCCCCCCCCCCCCEEE
IGGMVVVGSVKRDSQSLEVRFQVEDIGPKVTVIYDGILPDLFREGQGIVAQGVLVDATTV
ECCEEEEECCCCCCCEEEEEEEEECCCCEEEEEECCCCHHHHHCCCCEEECCEEEECCHH
KAHEVLAKHDEEYMPPEVAEAMKKTH
HHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNPRRKKRLGLILALVLGASATVGLMLYALNQNMDLFYTPTELVNGKPDGTKPEVGQRLR
CCCHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCEEEECCHHHHCCCCCCCCCCCCCEEE
IGGMVVVGSVKRDSQSLEVRFQVEDIGPKVTVIYDGILPDLFREGQGIVAQGVLVDATTV
ECCEEEEECCCCCCCEEEEEEEEECCCCEEEEEECCCCHHHHHCCCCEEECCEEEECCHH
KAHEVLAKHDEEYMPPEVAEAMKKTH
HHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA