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The map label for this gene is ptsG [H]

Identifier: 209695688

GI number: 209695688

Start: 2421738

End: 2423168

Strand: Direct

Name: ptsG [H]

Synonym: VSAL_I2252

Alternate gene names: 209695688

Gene position: 2421738-2423168 (Clockwise)

Preceding gene: 209695687

Following gene: 209695692

Centisome position: 72.83

GC content: 42.28

Gene sequence:

>1431_bases
ATGTTTAAAAACCTTTTTGCCAGTTTACAGAAAGTTGGTAAGGCACTTATGTTGCCAGTATCAGTTCTTCCTGTTGCTGG
TATTCTTTTAGGAGTTGGTGCAGCCAACTTTAGTTTCCTTCCAGAAGTTGTTTCTCATTTAATGGAACAAGCTGGTGGTT
CAGTATTCGGCCAAATGGCACTACTCTTTGCAGTTGGTGTTGCTCTTGGTTTCACAAATAATGACGGTGTAGCAGGTCTT
TCTGCTATCGTTGGTTATGGCATCATGACAGCAACACTAGGCGTAATGGCTGAAGTGATGGGTGTTGATGGCATCGAAAC
GGGTGTTCTTGGTGGTATTCTTGCGGGTGGTGTTGCTGGTTGGGCATTTAATCGTTTTTACCGTATTCAACTTCCTGAAT
ATTTAGGCTTCTTTGCTGGTAAACGTGCAGTACCTATCATTACTGGTTTTGTATCAATTGCTTTGGGTGTGATTTTATCT
GTTATCTGGCCACCAATTGGTTCAGTAATCGCGTCTTTCTCTGATTGGGCTGCTCATCAGAACCCAGTAGCTGCTTTTGG
TATCTACGGTGTTGTTGAACGTTCTCTAATTCCTTTTGGTTTACACCATATCTGGAACGTACCATTCTTCTATGAAGCGG
GTTCTTGTGTAAATAATGCGGGTGAACAAGTTCACGGTATTATGACTTGTTTCCTAACCGCTGATGATGCGTCTCGTGCT
GCGAGTAATGGTTTCGGTCAACTTGCTGGTGGTTACTTGTTTAAAATGTTCGGTCTTCCTGCTGCTGCAATCGCGATTGC
ACATTCAGCAAAACCTGAAAACCGTGCAAAAGTAATGGGTATCATGGCATCTGCTGCGTTAACTTCATTCCTTACTGGTA
TTACAGAACCGATTGAATTTGCATTCTTATTTGTTGCTCCTGTTCTTTATGCTATTCACGCAGCTCTTGCTGGCGTGGCA
TACATGCTGACTAACGCATTAGGTATTGTTCACGGTCACACATTCTCAAATGGTTTCATTGACTTCATTGTTCAATCTCC
ACATGCTGAGAAAATGCCTCTTCTAATTGGATTAGGTCTTGTTTACGCTGCTGTTTACTACATCGTATTCCGCTTTGTGA
TTAAAGCAATGAACCTTAAAACGCCAGGTCGTGAAGATGAAGATGACAATGCAGCTCCAGTAGTAACTGGTACTGAATTG
GCAGGTGAACTTGTTGCTGCCTTTGGTGGTAAAGAGAACATCACCAACTTAGATGCTTGTATTACTCGCTTACGCGTTTC
TGTAGCAAGTGTAGAAGCGGTAAACCAAGACAGACTGAAACAACTAGGTGCAGCAGGCGTTGTTGTTGCTGGTTCTGGTG
TTCAGGCAATTTTTGGTACTAAATCAGATAACTTGAAAACAGACATGAATGAATGGATTAGCCATAACTAA

Upstream 100 bases:

>100_bases
AGCCACGAATTAAGCTATCAGAATGTGAATTTGAACTAATCCTCGCTTAAAGCATGTTTTATCCAGAATTCAGGTTATTT
ATAAATATTAGGAGCAAAAC

Downstream 100 bases:

>100_bases
TTCCTGATTTTATGAATGAAAAAAAGGAGACTTTCGAGTCTCCTTTTTTATTGCCAGTCTAAAGAGTACGGTCTTTATTT
TGAGGGAAACTGACTTCATG

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MFKNLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGL
SAIVGYGIMTATLGVMAEVMGVDGIETGVLGGILAGGVAGWAFNRFYRIQLPEYLGFFAGKRAVPIITGFVSIALGVILS
VIWPPIGSVIASFSDWAAHQNPVAAFGIYGVVERSLIPFGLHHIWNVPFFYEAGSCVNNAGEQVHGIMTCFLTADDASRA
ASNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAALAGVA
YMLTNALGIVHGHTFSNGFIDFIVQSPHAEKMPLLIGLGLVYAAVYYIVFRFVIKAMNLKTPGREDEDDNAAPVVTGTEL
AGELVAAFGGKENITNLDACITRLRVSVASVEAVNQDRLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISHN

Sequences:

>Translated_476_residues
MFKNLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGL
SAIVGYGIMTATLGVMAEVMGVDGIETGVLGGILAGGVAGWAFNRFYRIQLPEYLGFFAGKRAVPIITGFVSIALGVILS
VIWPPIGSVIASFSDWAAHQNPVAAFGIYGVVERSLIPFGLHHIWNVPFFYEAGSCVNNAGEQVHGIMTCFLTADDASRA
ASNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAALAGVA
YMLTNALGIVHGHTFSNGFIDFIVQSPHAEKMPLLIGLGLVYAAVYYIVFRFVIKAMNLKTPGREDEDDNAAPVVTGTEL
AGELVAAFGGKENITNLDACITRLRVSVASVEAVNQDRLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISHN
>Mature_476_residues
MFKNLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGL
SAIVGYGIMTATLGVMAEVMGVDGIETGVLGGILAGGVAGWAFNRFYRIQLPEYLGFFAGKRAVPIITGFVSIALGVILS
VIWPPIGSVIASFSDWAAHQNPVAAFGIYGVVERSLIPFGLHHIWNVPFFYEAGSCVNNAGEQVHGIMTCFLTADDASRA
ASNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAALAGVA
YMLTNALGIVHGHTFSNGFIDFIVQSPHAEKMPLLIGLGLVYAAVYYIVFRFVIKAMNLKTPGREDEDDNAAPVVTGTEL
AGELVAAFGGKENITNLDACITRLRVSVASVEAVNQDRLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISHN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=486, Percent_Identity=65.2263374485597, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI1786894, Length=486, Percent_Identity=38.2716049382716, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1787908, Length=519, Percent_Identity=33.140655105973, Blast_Score=256, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 49853; Mature: 49853

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LLFAVGVALGFTNNDGVAGLSAIVGYGIMTATLGVMAEVMGVDGIETGVLGGILAGGVAG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
WAFNRFYRIQLPEYLGFFAGKRAVPIITGFVSIALGVILSVIWPPIGSVIASFSDWAAHQ
HHHHHEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
NPVAAFGIYGVVERSLIPFGLHHIWNVPFFYEAGSCVNNAGEQVHGIMTCFLTADDASRA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHEEEECCCHHHH
ASNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEF
HCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFLFVAPVLYAIHAALAGVAYMLTNALGIVHGHTFSNGFIDFIVQSPHAEKMPLLIGLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCCCCCCHHHHHHHH
VYAAVYYIVFRFVIKAMNLKTPGREDEDDNAAPVVTGTELAGELVAAFGGKENITNLDAC
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCHHHHH
ITRLRVSVASVEAVNQDRLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISHN
HHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MFKNLFASLQKVGKALMLPVSVLPVAGILLGVGAANFSFLPEVVSHLMEQAGGSVFGQMA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
LLFAVGVALGFTNNDGVAGLSAIVGYGIMTATLGVMAEVMGVDGIETGVLGGILAGGVAG
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
WAFNRFYRIQLPEYLGFFAGKRAVPIITGFVSIALGVILSVIWPPIGSVIASFSDWAAHQ
HHHHHEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
NPVAAFGIYGVVERSLIPFGLHHIWNVPFFYEAGSCVNNAGEQVHGIMTCFLTADDASRA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHEEEECCCHHHH
ASNGFGQLAGGYLFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEF
HCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFLFVAPVLYAIHAALAGVAYMLTNALGIVHGHTFSNGFIDFIVQSPHAEKMPLLIGLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCCCCCCHHHHHHHH
VYAAVYYIVFRFVIKAMNLKTPGREDEDDNAAPVVTGTELAGELVAAFGGKENITNLDAC
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCCCCCHHHHH
ITRLRVSVASVEAVNQDRLKQLGAAGVVVAGSGVQAIFGTKSDNLKTDMNEWISHN
HHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]