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The map label for this gene is pabC [H]

Identifier: 209695679

GI number: 209695679

Start: 2413782

End: 2414588

Strand: Direct

Name: pabC [H]

Synonym: VSAL_I2243

Alternate gene names: 209695679

Gene position: 2413782-2414588 (Clockwise)

Preceding gene: 209695678

Following gene: 209695680

Centisome position: 72.59

GC content: 38.29

Gene sequence:

>807_bases
ATGTATTGGGTTAACGGGGTAGTTACGGATTCATTACCACTCACTGATCGTAGTATTCAATATGGTGATGGTTCTTTTAC
GACCATGAAAGTTGAGCGGGGGAGAGTCCGTTTATGGGACTTGCACTTAGCTCGTTTAAAAGAAGCGTCAAAACGATTAG
ACATCAAGATTGAAGATTGGCTTCTTCTTGAAACGCAAATTGAATCTTGCGCCCATGAGCTTCAAGATGGTGGCATTAAG
ATACTGATCAGTCGAGGGAGTGGTGGACGAGGTTATTCTCCTGAGGGCTGCCATGATACACAAATTATTGTGTCGACTTT
TTCTTATCCAACGTATTATCAGAATTGGAAAGAAGGCGGTATTAGTTTGATGCTTTGTGAAACCCAGTTAGGGTTGTCAC
CATTACTTGCAGGTATGAAGCATACAAACCGATTAGAACAAGTTTTGATTAAGAAAGAAATAGCAAAAACAACGTATCTT
GATGGCGTGGTTCTTGATCTTAATAACAAAGTTATAGAGACTTCAATAGGCAATATTTTTTGGGTGAAGGGTGATAATAT
TTACACCCCTAATTTATCAAACTCTGGTGTTGAAGGTGTGATGAAAGCACACATTTATGCATTGGCTAATTTACATGGGC
TAACGTTGTTCGAAACATCAATTTATGTAGACGAACTATGCATGGCCGATGAAGTTTTTATTAGTAATTCATTATTTGAA
ATAGTGCCAATTAACGCAATTGGCAATACGACTTTTGACAGTCATAAGTTGTCTCATTGGTTTCAGGAGAAATTGTACTC
GTGCTAA

Upstream 100 bases:

>100_bases
AATAACTTGTTTGTGAGGCTTAATTAGTTTCACTCAGTTAGTTATACTAGAAAGCGGCTTGATATTATATCAAGCCGCTT
TTTTCTGTTTGGAGTACTGT

Downstream 100 bases:

>100_bases
AGAAATTTTTATTCCTTATTTTAATTATCATCATTGGATCTGTAGGTTTTGGATTTTGGATCTATCAACAAGCAATTAAA
TTTACAGAGCAACCAGTTTT

Product: 4-amino-4-deoxychorismate lyase

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MYWVNGVVTDSLPLTDRSIQYGDGSFTTMKVERGRVRLWDLHLARLKEASKRLDIKIEDWLLLETQIESCAHELQDGGIK
ILISRGSGGRGYSPEGCHDTQIIVSTFSYPTYYQNWKEGGISLMLCETQLGLSPLLAGMKHTNRLEQVLIKKEIAKTTYL
DGVVLDLNNKVIETSIGNIFWVKGDNIYTPNLSNSGVEGVMKAHIYALANLHGLTLFETSIYVDELCMADEVFISNSLFE
IVPINAIGNTTFDSHKLSHWFQEKLYSC

Sequences:

>Translated_268_residues
MYWVNGVVTDSLPLTDRSIQYGDGSFTTMKVERGRVRLWDLHLARLKEASKRLDIKIEDWLLLETQIESCAHELQDGGIK
ILISRGSGGRGYSPEGCHDTQIIVSTFSYPTYYQNWKEGGISLMLCETQLGLSPLLAGMKHTNRLEQVLIKKEIAKTTYL
DGVVLDLNNKVIETSIGNIFWVKGDNIYTPNLSNSGVEGVMKAHIYALANLHGLTLFETSIYVDELCMADEVFISNSLFE
IVPINAIGNTTFDSHKLSHWFQEKLYSC
>Mature_268_residues
MYWVNGVVTDSLPLTDRSIQYGDGSFTTMKVERGRVRLWDLHLARLKEASKRLDIKIEDWLLLETQIESCAHELQDGGIK
ILISRGSGGRGYSPEGCHDTQIIVSTFSYPTYYQNWKEGGISLMLCETQLGLSPLLAGMKHTNRLEQVLIKKEIAKTTYL
DGVVLDLNNKVIETSIGNIFWVKGDNIYTPNLSNSGVEGVMKAHIYALANLHGLTLFETSIYVDELCMADEVFISNSLFE
IVPINAIGNTTFDSHKLSHWFQEKLYSC

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=261, Percent_Identity=39.8467432950192, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI48994963, Length=214, Percent_Identity=26.1682242990654, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017824
- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 30174; Mature: 30174

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWVNGVVTDSLPLTDRSIQYGDGSFTTMKVERGRVRLWDLHLARLKEASKRLDIKIEDW
CEEECEEEECCCCCCCCCEEECCCCEEEEEEECCCEEEEHHHHHHHHHHHHHCCEEECCE
LLLETQIESCAHELQDGGIKILISRGSGGRGYSPEGCHDTQIIVSTFSYPTYYQNWKEGG
EEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCC
ISLMLCETQLGLSPLLAGMKHTNRLEQVLIKKEIAKTTYLDGVVLDLNNKVIETSIGNIF
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCEEE
WVKGDNIYTPNLSNSGVEGVMKAHIYALANLHGLTLFETSIYVDELCMADEVFISNSLFE
EEECCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEE
IVPINAIGNTTFDSHKLSHWFQEKLYSC
EEEECCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYWVNGVVTDSLPLTDRSIQYGDGSFTTMKVERGRVRLWDLHLARLKEASKRLDIKIEDW
CEEECEEEECCCCCCCCCEEECCCCEEEEEEECCCEEEEHHHHHHHHHHHHHCCEEECCE
LLLETQIESCAHELQDGGIKILISRGSGGRGYSPEGCHDTQIIVSTFSYPTYYQNWKEGG
EEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCC
ISLMLCETQLGLSPLLAGMKHTNRLEQVLIKKEIAKTTYLDGVVLDLNNKVIETSIGNIF
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCEEEEECCCEEE
WVKGDNIYTPNLSNSGVEGVMKAHIYALANLHGLTLFETSIYVDELCMADEVFISNSLFE
EEECCEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEE
IVPINAIGNTTFDSHKLSHWFQEKLYSC
EEEECCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]