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The map label for this gene is fabD [H]

Identifier: 209695676

GI number: 209695676

Start: 2410270

End: 2411193

Strand: Direct

Name: fabD [H]

Synonym: VSAL_I2240

Alternate gene names: 209695676

Gene position: 2410270-2411193 (Clockwise)

Preceding gene: 209695675

Following gene: 209695677

Centisome position: 72.49

GC content: 41.67

Gene sequence:

>924_bases
ATGAGCAATTTTGCTATCGTTTTTCCAGGCCAAGGCTCACAAGCTGTAGGCATGCTTGCTGAATTAGGTGAGCAACATGA
AGTGGTAACACAAACTTTTGCAGAAGCATCTGAAGCATTAGGTTATGACTTATGGTCTTTGGTTCAAAATGGTCCAGCTG
AAGATTTAAATCAAACATTTCGCACTCAGCCAGCATTATTAGCAACCTCTGTTGCATTATGGCGTGTGTGGCAAGAACAA
GGCTTAGCACAACCAAGTGTTTTAGCTGGTCATAGTCTTGGTGAGTATTCTGCTCTTGTCTGTGCTGGTGTTATTGACTT
TAAAGAAGCGATAAAATTAGTTGAGCTACGTGGTCAATTAATGCAAGAAGCGGTTCCTGCGGGGGTTGGTGCTATGTTTG
CTATCATCGGCTTAGACAATGATTCTATTGCTAAAGCATGTGAAGATGCAGCACAAGATGAAGTCGTTTCTCCTGTTAAC
TTTAATTCTCCAGGTCAAGTTGTTATTGCGGGTAATAAAGATGCTGTTGAGCGTGCTGGTGTATTGTGTAAAGAAGCGGG
CGCTAAGCGAGCACTTCCTCTACCAGTATCAGTGCCTTCTCATTGTGCATTAATGAAGCCTGCAGCTGATAAATTAGCCG
TTGCGTTAGAAAGCATTGAGTTCTCAACACCTGTTTTACCTGTTATTAATAACGTTGATGTTATTGCAGAGACGGATCCT
GAAAAAATTAAAGACGCACTTGTTCGTCAATTATATTGTCCAGTACGTTGGACTGAAGTCGTTGAACAAATGGCTGAACA
AGGTGTCGAAATGTTGTATGAAGTTGGTCCAGGTAAAGTACTTACTGGTTTAACTAAACGAATCGTAAAATCACTTAGCG
CTGCAGCGGTTAATGATGCCGCTTCTCTTGAAGCTGCTAAGTAA

Upstream 100 bases:

>100_bases
TGGTGGCTTTACGTGGGGCTCTGCGCTCGTTAAATTTTAGTTTGATTGTTGGGATGTCATCCCACTTTCTTTCTTTGTTT
ATTTAAAGGAAATAATACCC

Downstream 100 bases:

>100_bases
TTAAAGGGAAAATTAAATGATGAATTTAGAAGGCAAAATTGCCTTAGTTACTGGCGCTAGCCGTGGTATTGGTCGTGCTA
TTGCTGAGCAATTAGTGTCT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSNFAIVFPGQGSQAVGMLAELGEQHEVVTQTFAEASEALGYDLWSLVQNGPAEDLNQTFRTQPALLATSVALWRVWQEQ
GLAQPSVLAGHSLGEYSALVCAGVIDFKEAIKLVELRGQLMQEAVPAGVGAMFAIIGLDNDSIAKACEDAAQDEVVSPVN
FNSPGQVVIAGNKDAVERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADKLAVALESIEFSTPVLPVINNVDVIAETDP
EKIKDALVRQLYCPVRWTEVVEQMAEQGVEMLYEVGPGKVLTGLTKRIVKSLSAAAVNDAASLEAAK

Sequences:

>Translated_307_residues
MSNFAIVFPGQGSQAVGMLAELGEQHEVVTQTFAEASEALGYDLWSLVQNGPAEDLNQTFRTQPALLATSVALWRVWQEQ
GLAQPSVLAGHSLGEYSALVCAGVIDFKEAIKLVELRGQLMQEAVPAGVGAMFAIIGLDNDSIAKACEDAAQDEVVSPVN
FNSPGQVVIAGNKDAVERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADKLAVALESIEFSTPVLPVINNVDVIAETDP
EKIKDALVRQLYCPVRWTEVVEQMAEQGVEMLYEVGPGKVLTGLTKRIVKSLSAAAVNDAASLEAAK
>Mature_306_residues
SNFAIVFPGQGSQAVGMLAELGEQHEVVTQTFAEASEALGYDLWSLVQNGPAEDLNQTFRTQPALLATSVALWRVWQEQG
LAQPSVLAGHSLGEYSALVCAGVIDFKEAIKLVELRGQLMQEAVPAGVGAMFAIIGLDNDSIAKACEDAAQDEVVSPVNF
NSPGQVVIAGNKDAVERAGVLCKEAGAKRALPLPVSVPSHCALMKPAADKLAVALESIEFSTPVLPVINNVDVIAETDPE
KIKDALVRQLYCPVRWTEVVEQMAEQGVEMLYEVGPGKVLTGLTKRIVKSLSAAAVNDAASLEAAK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=33.4448160535117, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=41.8181818181818, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=71.5686274509804, Blast_Score=429, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=29.5918367346939, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=298, Percent_Identity=29.1946308724832, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24665753, Length=308, Percent_Identity=32.7922077922078, Blast_Score=134, Evalue=9e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32476; Mature: 32344

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFAIVFPGQGSQAVGMLAELGEQHEVVTQTFAEASEALGYDLWSLVQNGPAEDLNQTF
CCCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RTQPALLATSVALWRVWQEQGLAQPSVLAGHSLGEYSALVCAGVIDFKEAIKLVELRGQL
HCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPAGVGAMFAIIGLDNDSIAKACEDAAQDEVVSPVNFNSPGQVVIAGNKDAVERAG
HHHHHCCCHHHHEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHH
VLCKEAGAKRALPLPVSVPSHCALMKPAADKLAVALESIEFSTPVLPVINNVDVIAETDP
HHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEECCCH
EKIKDALVRQLYCPVRWTEVVEQMAEQGVEMLYEVGPGKVLTGLTKRIVKSLSAAAVNDA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCH
ASLEAAK
HHCCCCC
>Mature Secondary Structure 
SNFAIVFPGQGSQAVGMLAELGEQHEVVTQTFAEASEALGYDLWSLVQNGPAEDLNQTF
CCCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RTQPALLATSVALWRVWQEQGLAQPSVLAGHSLGEYSALVCAGVIDFKEAIKLVELRGQL
HCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQEAVPAGVGAMFAIIGLDNDSIAKACEDAAQDEVVSPVNFNSPGQVVIAGNKDAVERAG
HHHHHCCCHHHHEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHH
VLCKEAGAKRALPLPVSVPSHCALMKPAADKLAVALESIEFSTPVLPVINNVDVIAETDP
HHHHHCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEECCCH
EKIKDALVRQLYCPVRWTEVVEQMAEQGVEMLYEVGPGKVLTGLTKRIVKSLSAAAVNDA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCH
ASLEAAK
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]