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The map label for this gene is norW [H]

Identifier: 209695637

GI number: 209695637

Start: 2365334

End: 2366479

Strand: Direct

Name: norW [H]

Synonym: VSAL_I2200

Alternate gene names: 209695637

Gene position: 2365334-2366479 (Clockwise)

Preceding gene: 209695636

Following gene: 209695638

Centisome position: 71.13

GC content: 40.31

Gene sequence:

>1146_bases
ATGAGTTTACCAATCGTTATTATTGGCAGTGGTTTTGCTTCTTATCAACTAATTAAAACGATCCGTCGTACAGAAGTAGA
TTGTCCTATTCATGTATTTACGAATGATGATGGCCACGATTATAACAAGCCAGATTTAAGTCATGTGTTTTCAAAGCAAC
AGAGTCATGATGATGTAGTGACGCTATCAGGCTCCGATTTTTCTGAACAATACAATGTGGTATTGCATACCCGCACTTTA
GTTGAGTCGATTGATACCATCAGTCAAACCATTACGGTGAAAGACGAGGTGTTTTCTTACGCTAAATTGGTATTAGCCAC
GGGCTCTCAAACGTTTATCCCACCTTTTAAAGGGGACGGATGTGGTGAGATCCTTACGTTAAACAGCTTAAAAGAATTTG
CGGTTATTCATAAAAAAGTGGTGAGTTCACAAAGCATACTCGTTATTGGTGGTGGACTGATAGGCACAGAGTTAACAATG
GATCTTGCGGGTGCAGGTAAACACGTAACGGTGGTTGAGCCGAATACGCATCTTCTTGCCAATATGATCCCTGACTTTAT
TTCTTTGCCTTTAGAGAATGCGTGCAGAGATAAAGGCGTGGTTATTACGCTTTCTGATGGTGTTCAAAGTGTAAATCAGA
GTGGTAGTGGCTTTATAGTCACGACAATGAAGGGTCAGTCTTATCAAGTTGATTGTGTTATTTCAGCCGCTGGTCTAAAA
CCCAATACTCAGTTAGCGAAAGACGCTGATATTCGTGTTAATCGTGGAGTTGTGGTGGATTCAACCTTACAAACGTCGGC
TAGAAATGTGTATGCGTTAGGCGATTGCGCAGAAATAGAAGGCAAGGTAATGGCCTATCTTCAACCTATTTTACTGAGTG
CAAATGCATTAGCTAAGACATTGCTGGGCTTGAACACGCCGTTGGTATTACCGAATATGATGGTGAAAGTGAAAACCCCT
ATTTACCCAATACAGCTTGCGGGTAATACATCAAGTCATATCCATCGTTGGTCTATTGAACTTGATGAACAGGGGATATG
TGCTAAAGCTTATGACGAAAAGGATAACCTAACCGGATTTGTTGTGACAAAAGAACAGATGAAAAAGGCATTTCCTTTAT
TTAGAGAGATACATAATACGAATTAA

Upstream 100 bases:

>100_bases
AACCAAACACGGCGTGGATTGATGTGCCCGATTATTTCTTATGCCCTGAGTGTAATTTAGGCAAAGATGTCTTTGTTGAA
GTTAAATAGGGAGTGAAATA

Downstream 100 bases:

>100_bases
TAGAGGTGAATTATGACAGAAATTCCTCATGGCTTAATAAAAGGCGTGGTTCTGAGTCGCTATGATTGGACCGATCGTTT
ATTCAGTTTGTATGTTGAGG

Product: nitric oxide reductase

Products: NAD; reduced flavorubredoxin; H2O [C]

Alternate protein names: Flavorubredoxin reductase; FlRd-reductase; FlavoRb reductase [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSLPIVIIGSGFASYQLIKTIRRTEVDCPIHVFTNDDGHDYNKPDLSHVFSKQQSHDDVVTLSGSDFSEQYNVVLHTRTL
VESIDTISQTITVKDEVFSYAKLVLATGSQTFIPPFKGDGCGEILTLNSLKEFAVIHKKVVSSQSILVIGGGLIGTELTM
DLAGAGKHVTVVEPNTHLLANMIPDFISLPLENACRDKGVVITLSDGVQSVNQSGSGFIVTTMKGQSYQVDCVISAAGLK
PNTQLAKDADIRVNRGVVVDSTLQTSARNVYALGDCAEIEGKVMAYLQPILLSANALAKTLLGLNTPLVLPNMMVKVKTP
IYPIQLAGNTSSHIHRWSIELDEQGICAKAYDEKDNLTGFVVTKEQMKKAFPLFREIHNTN

Sequences:

>Translated_381_residues
MSLPIVIIGSGFASYQLIKTIRRTEVDCPIHVFTNDDGHDYNKPDLSHVFSKQQSHDDVVTLSGSDFSEQYNVVLHTRTL
VESIDTISQTITVKDEVFSYAKLVLATGSQTFIPPFKGDGCGEILTLNSLKEFAVIHKKVVSSQSILVIGGGLIGTELTM
DLAGAGKHVTVVEPNTHLLANMIPDFISLPLENACRDKGVVITLSDGVQSVNQSGSGFIVTTMKGQSYQVDCVISAAGLK
PNTQLAKDADIRVNRGVVVDSTLQTSARNVYALGDCAEIEGKVMAYLQPILLSANALAKTLLGLNTPLVLPNMMVKVKTP
IYPIQLAGNTSSHIHRWSIELDEQGICAKAYDEKDNLTGFVVTKEQMKKAFPLFREIHNTN
>Mature_380_residues
SLPIVIIGSGFASYQLIKTIRRTEVDCPIHVFTNDDGHDYNKPDLSHVFSKQQSHDDVVTLSGSDFSEQYNVVLHTRTLV
ESIDTISQTITVKDEVFSYAKLVLATGSQTFIPPFKGDGCGEILTLNSLKEFAVIHKKVVSSQSILVIGGGLIGTELTMD
LAGAGKHVTVVEPNTHLLANMIPDFISLPLENACRDKGVVITLSDGVQSVNQSGSGFIVTTMKGQSYQVDCVISAAGLKP
NTQLAKDADIRVNRGVVVDSTLQTSARNVYALGDCAEIEGKVMAYLQPILLSANALAKTLLGLNTPLVLPNMMVKVKTPI
YPIQLAGNTSSHIHRWSIELDEQGICAKAYDEKDNLTGFVVTKEQMKKAFPLFREIHNTN

Specific function: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI4757732, Length=221, Percent_Identity=25.3393665158371, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI22202629, Length=221, Percent_Identity=25.3393665158371, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789065, Length=377, Percent_Identity=44.2970822281167, Blast_Score=334, Evalue=6e-93,
Organism=Escherichia coli, GI1788892, Length=275, Percent_Identity=25.4545454545455, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789765, Length=323, Percent_Identity=24.7678018575851, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559934, Length=280, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573993, Length=314, Percent_Identity=22.2929936305732, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581020, Length=314, Percent_Identity=22.2929936305732, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639257, Length=278, Percent_Identity=23.021582733813, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281359715, Length=278, Percent_Identity=23.021582733813, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281359713, Length=278, Percent_Identity=23.021582733813, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639250, Length=278, Percent_Identity=23.021582733813, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI18543267, Length=278, Percent_Identity=23.021582733813, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639252, Length=278, Percent_Identity=23.021582733813, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 41375; Mature: 41244

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPIVIIGSGFASYQLIKTIRRTEVDCPIHVFTNDDGHDYNKPDLSHVFSKQQSHDDVV
CCCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEE
TLSGSDFSEQYNVVLHTRTLVESIDTISQTITVKDEVFSYAKLVLATGSQTFIPPFKGDG
EECCCCCCCCEEEEEEHHHHHHHHHHHHHEEEEHHHHHHHHHHEEECCCCEECCCCCCCC
CGEILTLNSLKEFAVIHKKVVSSQSILVIGGGLIGTELTMDLAGAGKHVTVVEPNTHLLA
CCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCEECCEEEEEECCCCCEEEEECCCCHHHH
NMIPDFISLPLENACRDKGVVITLSDGVQSVNQSGSGFIVTTMKGQSYQVDCVISAAGLK
HHHHHHHHCCCHHHCCCCCEEEEECCCHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCC
PNTQLAKDADIRVNRGVVVDSTLQTSARNVYALGDCAEIEGKVMAYLQPILLSANALAKT
CCCCCCCCCCEEEECCEEEECHHHHCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHH
LLGLNTPLVLPNMMVKVKTPIYPIQLAGNTSSHIHRWSIELDEQGICAKAYDEKDNLTGF
HHCCCCCEECCCEEEEEECCEEEEEECCCCCCCEEEEEEEECCCCCEEECCCCCCCCEEE
VVTKEQMKKAFPLFREIHNTN
EEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLPIVIIGSGFASYQLIKTIRRTEVDCPIHVFTNDDGHDYNKPDLSHVFSKQQSHDDVV
CCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCEE
TLSGSDFSEQYNVVLHTRTLVESIDTISQTITVKDEVFSYAKLVLATGSQTFIPPFKGDG
EECCCCCCCCEEEEEEHHHHHHHHHHHHHEEEEHHHHHHHHHHEEECCCCEECCCCCCCC
CGEILTLNSLKEFAVIHKKVVSSQSILVIGGGLIGTELTMDLAGAGKHVTVVEPNTHLLA
CCCEEEHHHHHHHHHHHHHHHCCCEEEEEECCEECCEEEEEECCCCCEEEEECCCCHHHH
NMIPDFISLPLENACRDKGVVITLSDGVQSVNQSGSGFIVTTMKGQSYQVDCVISAAGLK
HHHHHHHHCCCHHHCCCCCEEEEECCCHHHHCCCCCCEEEEEECCCCEEEEEEEEECCCC
PNTQLAKDADIRVNRGVVVDSTLQTSARNVYALGDCAEIEGKVMAYLQPILLSANALAKT
CCCCCCCCCCEEEECCEEEECHHHHCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHH
LLGLNTPLVLPNMMVKVKTPIYPIQLAGNTSSHIHRWSIELDEQGICAKAYDEKDNLTGF
HHCCCCCEECCCEEEEEECCEEEEEECCCCCCCEEEEEEEECCCCCEEECCCCCCCCEEE
VVTKEQMKKAFPLFREIHNTN
EEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; oxidized flavorubredoxin; O2 [C]

Specific reaction: NADH + oxidized flavorubredoxin + O2 = NAD + reduced flavorubredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA