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The map label for this gene is citT [H]

Identifier: 209695623

GI number: 209695623

Start: 2348783

End: 2349457

Strand: Direct

Name: citT [H]

Synonym: VSAL_I2186

Alternate gene names: 209695623

Gene position: 2348783-2349457 (Clockwise)

Preceding gene: 209695620

Following gene: 209695624

Centisome position: 70.64

GC content: 41.63

Gene sequence:

>675_bases
GTGAGCAGTAAAGTAACCATCGTTATTGTCGAAGATGACATTGCTATTGCGGAAATACATCGTCGTAATTTAGATAAAAT
AGACGCGGTTGAGGTGATCGGTATTGCCGCAAGTAAAGAAGAAGCCGATACCTTGTTTGATGTGTTGAACCCAGATATGG
TGTTACTCGATATTTATTTACCTGATGGTAATGGGTTGGATATTTTGCGTGAGCTACGCCAAAAAGAAAACTCCCCAGAC
GTCATTTTAATTACCGCAGACAGAGACGTAAATACATTACAAGAAGCCATGCGTGGTGGTGTGATTGATTATTTGCTAAA
ACCGGTCATCTTTAGCCGATTAGAAGAGTCCATAAATAAGTATTTGAGCCAAAAGAAACAACTGACTGCTCGGCTTGATA
TTGATCAATCAATGGTGGATGCGATGCTACATTCTGGGGTCGCATCGCAAGTTACTCGTTTACCAAAAGGAATTGATGGA
GTAACTTTAGAAAAGGTACGACGTCTTTTTGAGAGTAAAACTAAATTAACCGCAGATCAGGCGGGGGAACTCTTTGGCGC
AAGCAGAACAACAGCGCGTCGTTATCTCGAATATTTGATTAGCTCTGGAGAGTTGAGTGCTGATCTGTCTTATGGCAGTG
TGGGGCGACCAGAGAGAACTTACTTTAAGCATTAA

Upstream 100 bases:

>100_bases
TACACAGTGAAACGGATGTAGGTACAGTGATGACCATCTATTTACCAAAAGAATGGCTTAAAAAGTCGTCATGATAAAAA
GAATGAAATAAGGATATTGA

Downstream 100 bases:

>100_bases
AGAGGGCAACATGACCCCAGCAACAAAATTATTAAAGAAATTAAAAATAGATCATCAGGTGCTTGAGTATCATCATGATT
CTAAAGCGCAAGCTTATGGA

Product: HTH-type transcriptional regulator, two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSSKVTIVIVEDDIAIAEIHRRNLDKIDAVEVIGIAASKEEADTLFDVLNPDMVLLDIYLPDGNGLDILRELRQKENSPD
VILITADRDVNTLQEAMRGGVIDYLLKPVIFSRLEESINKYLSQKKQLTARLDIDQSMVDAMLHSGVASQVTRLPKGIDG
VTLEKVRRLFESKTKLTADQAGELFGASRTTARRYLEYLISSGELSADLSYGSVGRPERTYFKH

Sequences:

>Translated_224_residues
MSSKVTIVIVEDDIAIAEIHRRNLDKIDAVEVIGIAASKEEADTLFDVLNPDMVLLDIYLPDGNGLDILRELRQKENSPD
VILITADRDVNTLQEAMRGGVIDYLLKPVIFSRLEESINKYLSQKKQLTARLDIDQSMVDAMLHSGVASQVTRLPKGIDG
VTLEKVRRLFESKTKLTADQAGELFGASRTTARRYLEYLISSGELSADLSYGSVGRPERTYFKH
>Mature_223_residues
SSKVTIVIVEDDIAIAEIHRRNLDKIDAVEVIGIAASKEEADTLFDVLNPDMVLLDIYLPDGNGLDILRELRQKENSPDV
ILITADRDVNTLQEAMRGGVIDYLLKPVIFSRLEESINKYLSQKKQLTARLDIDQSMVDAMLHSGVASQVTRLPKGIDGV
TLEKVRRLFESKTKLTADQAGELFGASRTTARRYLEYLISSGELSADLSYGSVGRPERTYFKH

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=223, Percent_Identity=37.6681614349776, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI1790566, Length=223, Percent_Identity=31.390134529148, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1788550, Length=87, Percent_Identity=39.0804597701149, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=102, Percent_Identity=39.2156862745098, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25011; Mature: 24880

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKVTIVIVEDDIAIAEIHRRNLDKIDAVEVIGIAASKEEADTLFDVLNPDMVLLDIYL
CCCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEE
PDGNGLDILRELRQKENSPDVILITADRDVNTLQEAMRGGVIDYLLKPVIFSRLEESINK
CCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YLSQKKQLTARLDIDQSMVDAMLHSGVASQVTRLPKGIDGVTLEKVRRLFESKTKLTADQ
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
AGELFGASRTTARRYLEYLISSGELSADLSYGSVGRPERTYFKH
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SSKVTIVIVEDDIAIAEIHRRNLDKIDAVEVIGIAASKEEADTLFDVLNPDMVLLDIYL
CCCEEEEEEECCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEE
PDGNGLDILRELRQKENSPDVILITADRDVNTLQEAMRGGVIDYLLKPVIFSRLEESINK
CCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YLSQKKQLTARLDIDQSMVDAMLHSGVASQVTRLPKGIDGVTLEKVRRLFESKTKLTADQ
HHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
AGELFGASRTTARRYLEYLISSGELSADLSYGSVGRPERTYFKH
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]