Click here to switch to the map view.

The map label for this gene is serC [H]

Identifier: 209695524

GI number: 209695524

Start: 2228872

End: 2229957

Strand: Reverse

Name: serC [H]

Synonym: VSAL_I2078

Alternate gene names: 209695524

Gene position: 2229957-2228872 (Counterclockwise)

Preceding gene: 209695525

Following gene: 209695523

Centisome position: 67.06

GC content: 36.37

Gene sequence:

>1086_bases
ATGCACACTAAATATAATTTTTCTGCAGGGCCTGCTGTTATTCCTACGAGTGTTTTACAACAAGTTCAACATGATATTCT
TGATTGGAAAGGAACTGGATTATCAATCATGGGATTTAGCCATCGTAGTTCTGAGTTTATGCAATTAGCAGAAGAGTCTG
AAATGATATTACGAGAACTAATGGAGGTCCCTGATAATTATCATGTCCTGTTTTGTCATGGTGGTGGAAGTGGTCAATTT
TCAGCGGTTCCATTGAATTTGGTGGATAAGTCACAAACAGCGGATTATGTTGTTAGCGGTCATTGGTCAAAGTATGCAGC
GATAGAGGCGAGTAAATTTTGTAAGGTTAATACCATCAATATTGTTCAGAGAAATAATCAAAAGCAATCACTCTTATCTC
CCGTTGATTGGCAATTATCACAGGATGCTCAGTATGTTTTCTTCTGTCCAAATGAAACGGTTGATGGGTTAGAGATTAAT
GAATTGCCTATTACAGATAAACCAATAATTGCAGATATGTCTTCATTCATATTGTCACGCCCAATTGATGTTTCTAAATA
TGGAATTATTTATGCGGGAGCTCAAAAAAATATTGGTCCAGCAGGATTAACGTTAGTTATCATTCGTGATGATTTATTGG
GAAAAGTGAGTCGTGAAATACCCACTATTTTTGATTATAAGGTATTGGCTGAAAATTATTCGATGCCAAATACACCGCCA
ACCTATCCATGGTACGTTGCTAATGAAGTCTTTAAATGGCTTAAGGAGATTGGCGGTGTATCGGCTATTTACAAGATAAA
TATAGAAAAAGCAGCGTTATTGTATGATGCAATTGATAACTCAAGTTTATATATTAATCATATAGATTCTGCCGCTCGTT
CAATCATGAATGTTCCATTTTATTTAAAGTCAGAAGCATTAACAGAAAAGTTTGTATCTCTTGCTCATACTGCGGGACTT
ACCTCCCTTAAGGGCCATAGCTCTGTCGGTGGTATTCGAGCATCAATCTATAATGCGATGCCGATAGAGGGAGTAAAGAC
ATTAGTAACTTTCATGAAGCAATTCGAAGAACAATTCTATAACTAA

Upstream 100 bases:

>100_bases
ACATCTACAAGTCGAATGAATCAATTACTAGGTGATTTTTTAGATAATTTAGTTGCAAAATATCGATACGATGATTGCAA
AGAGATCGCGAGATAATCTT

Downstream 100 bases:

>100_bases
TTAAGAAATGAAATGAAATACAAAGTAGAGATATCAAAAGACGAAAAAGTACTATTTGAAGTGTTGATTGATGACATTAA
TCGAAATATCTTAGAAGAGA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MHTKYNFSAGPAVIPTSVLQQVQHDILDWKGTGLSIMGFSHRSSEFMQLAEESEMILRELMEVPDNYHVLFCHGGGSGQF
SAVPLNLVDKSQTADYVVSGHWSKYAAIEASKFCKVNTINIVQRNNQKQSLLSPVDWQLSQDAQYVFFCPNETVDGLEIN
ELPITDKPIIADMSSFILSRPIDVSKYGIIYAGAQKNIGPAGLTLVIIRDDLLGKVSREIPTIFDYKVLAENYSMPNTPP
TYPWYVANEVFKWLKEIGGVSAIYKINIEKAALLYDAIDNSSLYINHIDSAARSIMNVPFYLKSEALTEKFVSLAHTAGL
TSLKGHSSVGGIRASIYNAMPIEGVKTLVTFMKQFEEQFYN

Sequences:

>Translated_361_residues
MHTKYNFSAGPAVIPTSVLQQVQHDILDWKGTGLSIMGFSHRSSEFMQLAEESEMILRELMEVPDNYHVLFCHGGGSGQF
SAVPLNLVDKSQTADYVVSGHWSKYAAIEASKFCKVNTINIVQRNNQKQSLLSPVDWQLSQDAQYVFFCPNETVDGLEIN
ELPITDKPIIADMSSFILSRPIDVSKYGIIYAGAQKNIGPAGLTLVIIRDDLLGKVSREIPTIFDYKVLAENYSMPNTPP
TYPWYVANEVFKWLKEIGGVSAIYKINIEKAALLYDAIDNSSLYINHIDSAARSIMNVPFYLKSEALTEKFVSLAHTAGL
TSLKGHSSVGGIRASIYNAMPIEGVKTLVTFMKQFEEQFYN
>Mature_361_residues
MHTKYNFSAGPAVIPTSVLQQVQHDILDWKGTGLSIMGFSHRSSEFMQLAEESEMILRELMEVPDNYHVLFCHGGGSGQF
SAVPLNLVDKSQTADYVVSGHWSKYAAIEASKFCKVNTINIVQRNNQKQSLLSPVDWQLSQDAQYVFFCPNETVDGLEIN
ELPITDKPIIADMSSFILSRPIDVSKYGIIYAGAQKNIGPAGLTLVIIRDDLLGKVSREIPTIFDYKVLAENYSMPNTPP
TYPWYVANEVFKWLKEIGGVSAIYKINIEKAALLYDAIDNSSLYINHIDSAARSIMNVPFYLKSEALTEKFVSLAHTAGL
TSLKGHSSVGGIRASIYNAMPIEGVKTLVTFMKQFEEQFYN

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=48.4764542936288, Blast_Score=342, Evalue=4e-94,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=45.2247191011236, Blast_Score=299, Evalue=2e-81,
Organism=Escherichia coli, GI1787136, Length=360, Percent_Identity=54.4444444444444, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17506897, Length=361, Percent_Identity=43.4903047091413, Blast_Score=312, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=41.4507772020725, Blast_Score=253, Evalue=3e-68,
Organism=Drosophila melanogaster, GI21356589, Length=357, Percent_Identity=45.9383753501401, Blast_Score=328, Evalue=3e-90,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40229; Mature: 40229

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTKYNFSAGPAVIPTSVLQQVQHDILDWKGTGLSIMGFSHRSSEFMQLAEESEMILREL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
MEVPDNYHVLFCHGGGSGQFSAVPLNLVDKSQTADYVVSGHWSKYAAIEASKFCKVNTIN
HHCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEECCCCCEEEEEHHHCEEEEEEE
IVQRNNQKQSLLSPVDWQLSQDAQYVFFCPNETVDGLEINELPITDKPIIADMSSFILSR
EEECCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHCC
PIDVSKYGIIYAGAQKNIGPAGLTLVIIRDDLLGKVSREIPTIFDYKVLAENYSMPNTPP
CCCCCCCEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
TYPWYVANEVFKWLKEIGGVSAIYKINIEKAALLYDAIDNSSLYINHIDSAARSIMNVPF
CCCHHHHHHHHHHHHHHCCCEEEEEEECHHHEEEEECCCCCEEEEEHHHHHHHHHHCCCC
YLKSEALTEKFVSLAHTAGLTSLKGHSSVGGIRASIYNAMPIEGVKTLVTFMKQFEEQFY
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
N
C
>Mature Secondary Structure
MHTKYNFSAGPAVIPTSVLQQVQHDILDWKGTGLSIMGFSHRSSEFMQLAEESEMILREL
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
MEVPDNYHVLFCHGGGSGQFSAVPLNLVDKSQTADYVVSGHWSKYAAIEASKFCKVNTIN
HHCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCEEEECCCCCEEEEEHHHCEEEEEEE
IVQRNNQKQSLLSPVDWQLSQDAQYVFFCPNETVDGLEINELPITDKPIIADMSSFILSR
EEECCCCHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHCC
PIDVSKYGIIYAGAQKNIGPAGLTLVIIRDDLLGKVSREIPTIFDYKVLAENYSMPNTPP
CCCCCCCEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
TYPWYVANEVFKWLKEIGGVSAIYKINIEKAALLYDAIDNSSLYINHIDSAARSIMNVPF
CCCHHHHHHHHHHHHHHCCCEEEEEEECHHHEEEEECCCCCEEEEEHHHHHHHHHHCCCC
YLKSEALTEKFVSLAHTAGLTSLKGHSSVGGIRASIYNAMPIEGVKTLVTFMKQFEEQFY
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA