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The map label for this gene is udp [H]

Identifier: 209695301

GI number: 209695301

Start: 1959321

End: 1960079

Strand: Reverse

Name: udp [H]

Synonym: VSAL_I1831

Alternate gene names: 209695301

Gene position: 1960079-1959321 (Counterclockwise)

Preceding gene: 209695302

Following gene: 209695299

Centisome position: 58.95

GC content: 42.82

Gene sequence:

>759_bases
ATGACAGCAGCAGTATTCCATTTAGGTGTTACAAAAGACGATCTTCAAGGCGCAGAAATGGCTATCATTCCAGGTGATCC
AGCACGTGTTCAGAAAATTGCAGAACAAATGGAAAACCCTAAGTTTTTAGCAAGTCACCGTGAATACACTGTGTATCTAG
CAGAATTAGAAGGCAAAAAAATTGTTGTTTGTTCTACTGGTATCGGTGGTCCATCAACGTCTATTGCTGTTGAAGAGTTA
GCTCAATTGGGTGTGCGTACCTTCTTACGTGTTGGTACTACTGGTGCAATCCAACCGCATGTAAATGTAGGTGATATGAT
TGTAACGACAGGTTCAGTTCGTTTAGATGGTGCGAGCTTGCATTTTGCTCCAATGGAATTCCCAGCCGTTGCTGATTTTG
ATGTTGCAACAGCAATGCGTAAAGCGGTTGTTGACCAAGGCGCGACAGTACATACCGGTGTTACTGCATCAAGTGATACA
TTCTACCCAGGTCAAGAGCGTTACGATACGTTCTCTGGTCGTGTTGTTAAGCGTTTCCAAGGTTCTATGCAAGAATGGCA
AGACATGGGCGTGTTAAACTTTGAGATGGAATCTGCAACGCTATTAACTATGTGTGCAAGCTCTGGTTTACGTGCGGGTT
GTGTTGCCGGTGTTATTATTAACCGTACTCAAAAAGAAACACCTGATCACGTGACATTAAAAGAAACTGAAGCTCGTTCA
ATTAAAGTTGTGATTGAGGCGGCTCGTAATCTTCTATAA

Upstream 100 bases:

>100_bases
CTTAGTCACACTAATGCCTCAACCGTTTGGGTAGAGTAACTTCATCGAATCAAATATAACTATTTAATTAACGCGACCCT
ACAATCGCAAGGAGTTAACC

Downstream 100 bases:

>100_bases
TCACTGAAGCGAATAGATATAAAAAATGCCGCTGATTCTTAACGAATAAGCGGCATTTTTATCGCTGTATATTGATGCAA
TTTAAAGTCCCGATAATAAA

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTAAVFHLGVTKDDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELEGKKIVVCSTGIGGPSTSIAVEEL
AQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVADFDVATAMRKAVVDQGATVHTGVTASSDT
FYPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKETPDHVTLKETEARS
IKVVIEAARNLL

Sequences:

>Translated_252_residues
MTAAVFHLGVTKDDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELEGKKIVVCSTGIGGPSTSIAVEEL
AQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVADFDVATAMRKAVVDQGATVHTGVTASSDT
FYPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKETPDHVTLKETEARS
IKVVIEAARNLL
>Mature_251_residues
TAAVFHLGVTKDDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELEGKKIVVCSTGIGGPSTSIAVEELA
QLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASLHFAPMEFPAVADFDVATAMRKAVVDQGATVHTGVTASSDTF
YPGQERYDTFSGRVVKRFQGSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKETPDHVTLKETEARSI
KVVIEAARNLL

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=248, Percent_Identity=73.7903225806452, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1790844, Length=215, Percent_Identity=30.6976744186047, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 27091; Mature: 26960

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVFHLGVTKDDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELEGKK
CCEEEEEECCCHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEEECCCEEEEEEEEECCCE
IVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASL
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEECCCEE
HFAPMEFPAVADFDVATAMRKAVVDQGATVHTGVTASSDTFYPGQERYDTFSGRVVKRFQ
EECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHH
GSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKETPDHVTLKETEARS
HHHHHHHHCCEEEEECCCHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCEEEECCCCCH
IKVVIEAARNLL
HHHHHHHHHHCC
>Mature Secondary Structure 
TAAVFHLGVTKDDLQGAEMAIIPGDPARVQKIAEQMENPKFLASHREYTVYLAELEGKK
CEEEEEECCCHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEEECCCEEEEEEEEECCCE
IVVCSTGIGGPSTSIAVEELAQLGVRTFLRVGTTGAIQPHVNVGDMIVTTGSVRLDGASL
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEECCCEE
HFAPMEFPAVADFDVATAMRKAVVDQGATVHTGVTASSDTFYPGQERYDTFSGRVVKRFQ
EECCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHH
GSMQEWQDMGVLNFEMESATLLTMCASSGLRAGCVAGVIINRTQKETPDHVTLKETEARS
HHHHHHHHCCEEEEECCCHHHHHHHHCCCCCHHHHHHHEEECCCCCCCCCEEEECCCCCH
IKVVIEAARNLL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2674901; 1379743; 9278503; 8506346; 8899705; 9661793; 7796917; 12499542 [H]