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The map label for this gene is yrhP [H]

Identifier: 209695273

GI number: 209695273

Start: 1921280

End: 1921921

Strand: Reverse

Name: yrhP [H]

Synonym: VSAL_I1798

Alternate gene names: 209695273

Gene position: 1921921-1921280 (Counterclockwise)

Preceding gene: 209695278

Following gene: 209695270

Centisome position: 57.8

GC content: 38.79

Gene sequence:

>642_bases
ATGGACATTAACGTGATTCTTGATTTTTGGGCGTTTTTTATCGCTATTCTCTTATTAACGATGACACCGGGGTTGGATAC
TGCTCTGGTTATTCGTAATACCACGCGTGGTGGCTGGAAAGACGGCATTACTTGCAGTTTTGGTATTTGTTGTGGCTTGT
TTGTGCATGCCACTATGTCAGCCATTGGTTTGTCAGTGTTGCTAGTCAGCTCTTCTGAGTTGTTTACTGTGATAAAAACC
ATCGGTGCTATCTATTTGATATGGTTAGGTATTCAATCAATAAGAAGTACGTTTAAAGCAGGGGCAGGGCTGACGATAGA
AAAGAACGTATCGCATGAAGACATACCTTTAACGCTTTCGTTTAAAGAGGGTTTTTTATCTAATATTTTAAATCCAAAAA
CGGCGGTTTTCTATTTGGCATTATTGCCTCAATTTATTAACCCTGAATATAATGCGTTTCTTCAATCTTTATTGATGGCG
AGCATCCATTTTATTATTGCGATGTGTTGGCAGGGAGGGATTGCGTTGTTGGTTGAAAAAGCAAAGCAGTTTATGTCTAG
CCCAACAGTTACAAAAAGAATTGAAAGGATCACGGGGGGAGTATTAATTGCCTTGGGTTTCAATTTGTTGGTTTCAAAAT
AA

Upstream 100 bases:

>100_bases
GTAAATATATGTGTCGAGTAATTACTCTGTTTTATAATTGATATTAATTTTAAGTAGTAATTAAAAGAAAAACCGATATA
TTAATTAATCTCACAATTAA

Downstream 100 bases:

>100_bases
ATTGATGATGTCGATAAAATAAGAATGCTATTCTTGAAAAGAGCACCTAATTTAAGATGCTCTTTTTTATGGGATGGTTT
AGCTGTCTTTTGATCGAACA

Product: amino acid transport protein, LysE type

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MDINVILDFWAFFIAILLLTMTPGLDTALVIRNTTRGGWKDGITCSFGICCGLFVHATMSAIGLSVLLVSSSELFTVIKT
IGAIYLIWLGIQSIRSTFKAGAGLTIEKNVSHEDIPLTLSFKEGFLSNILNPKTAVFYLALLPQFINPEYNAFLQSLLMA
SIHFIIAMCWQGGIALLVEKAKQFMSSPTVTKRIERITGGVLIALGFNLLVSK

Sequences:

>Translated_213_residues
MDINVILDFWAFFIAILLLTMTPGLDTALVIRNTTRGGWKDGITCSFGICCGLFVHATMSAIGLSVLLVSSSELFTVIKT
IGAIYLIWLGIQSIRSTFKAGAGLTIEKNVSHEDIPLTLSFKEGFLSNILNPKTAVFYLALLPQFINPEYNAFLQSLLMA
SIHFIIAMCWQGGIALLVEKAKQFMSSPTVTKRIERITGGVLIALGFNLLVSK
>Mature_213_residues
MDINVILDFWAFFIAILLLTMTPGLDTALVIRNTTRGGWKDGITCSFGICCGLFVHATMSAIGLSVLLVSSSELFTVIKT
IGAIYLIWLGIQSIRSTFKAGAGLTIEKNVSHEDIPLTLSFKEGFLSNILNPKTAVFYLALLPQFINPEYNAFLQSLLMA
SIHFIIAMCWQGGIALLVEKAKQFMSSPTVTKRIERITGGVLIALGFNLLVSK

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=201, Percent_Identity=27.8606965174129, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788099, Length=143, Percent_Identity=25.8741258741259, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI48994978, Length=193, Percent_Identity=24.8704663212435, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786522, Length=186, Percent_Identity=22.0430107526882, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23281; Mature: 23281

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINVILDFWAFFIAILLLTMTPGLDTALVIRNTTRGGWKDGITCSFGICCGLFVHATMS
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
AIGLSVLLVSSSELFTVIKTIGAIYLIWLGIQSIRSTFKAGAGLTIEKNVSHEDIPLTLS
HHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEE
FKEGFLSNILNPKTAVFYLALLPQFINPEYNAFLQSLLMASIHFIIAMCWQGGIALLVEK
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AKQFMSSPTVTKRIERITGGVLIALGFNLLVSK
HHHHHCCCHHHHHHHHHHCCCCEEEHHHHHCCC
>Mature Secondary Structure
MDINVILDFWAFFIAILLLTMTPGLDTALVIRNTTRGGWKDGITCSFGICCGLFVHATMS
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
AIGLSVLLVSSSELFTVIKTIGAIYLIWLGIQSIRSTFKAGAGLTIEKNVSHEDIPLTLS
HHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEE
FKEGFLSNILNPKTAVFYLALLPQFINPEYNAFLQSLLMASIHFIIAMCWQGGIALLVEK
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AKQFMSSPTVTKRIERITGGVLIALGFNLLVSK
HHHHHCCCHHHHHHHHHHCCCCEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]