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The map label for this gene is infC

Identifier: 209695238

GI number: 209695238

Start: 1871032

End: 1871583

Strand: Reverse

Name: infC

Synonym: VSAL_I1759

Alternate gene names: 209695238

Gene position: 1871583-1871032 (Counterclockwise)

Preceding gene: 209695239

Following gene: 209695237

Centisome position: 56.29

GC content: 44.2

Gene sequence:

>552_bases
ATTAAAGGCGGAAAAAGAGCCCAACAGCCGGCAAAACAAAATGCTCATCGTCTAAACGGTGAAATTATTGGCGTTAAAGA
AGTGCGCCTTACAGGTCTAGATGGCGAGTCAGTTGGCGTCGTTTCACTAAATGAAGCGTTAGACGTTGCACTTACAGCAG
GTGTCGATCTAGTTGAAATCAGCCCGAATGCCGAGCCACCAGTCTGTCGTGTGATGGACTATGGCAAATTCCTCTTCGAA
AAGGCCAAGGCTGCTAAAGAACAGAAGAAAAAACAGAAACAGGTCCAAACTAAAGAAATTAAATTTAGACCTGGGACAGA
TATTGGAGACTATCAGGTAAAACTACGCAACCTGACTGGTTTCCTGGAAGAAGGCAACAAGGTGAAGGTAACAATTCGCT
TCCGTGGCCGAGAGATGGCTCACCAAAACATCGGTGTTGACGTTCTTAATCGTTTGAAAGCGGATACTGAAGAATTTGCA
GTAGTCGAATCATTTCCAACGAGAATTGAAGGTCGCCAGATGATTATGGTGTTAGCCCCTAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
TAAAGGTAAAGATTTGGGTAAATTTAAAATTGATGATTTTGTTGCATTCCTGCAGCAAGAAGTTAGTACCCGAACGCTCA
ATACTGTGGAGGAATAAGGT

Downstream 100 bases:

>100_bases
TTTAGTGCATTCAAGTAGTAAAGTGGGGTAACTGCTCGCAGTTATCCTGTTTTATTCGCCTAATTACTATATGTTTAATC
ACGCAACAATGCGGAGTTAT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKGGKRAQQPAKQNAHRLNGEIIGVKEVRLTGLDGESVGVVSLNEALDVALTAGVDLVEISPNAEPPVCRVMDYGKFLFE
KAKAAKEQKKKQKQVQTKEIKFRPGTDIGDYQVKLRNLTGFLEEGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFA
VVESFPTRIEGRQMIMVLAPKKK

Sequences:

>Translated_183_residues
MKGGKRAQQPAKQNAHRLNGEIIGVKEVRLTGLDGESVGVVSLNEALDVALTAGVDLVEISPNAEPPVCRVMDYGKFLFE
KAKAAKEQKKKQKQVQTKEIKFRPGTDIGDYQVKLRNLTGFLEEGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFA
VVESFPTRIEGRQMIMVLAPKKK
>Mature_183_residues
MKGGKRAQQPAKQNAHRLNGEIIGVKEVRLTGLDGESVGVVSLNEALDVALTAGVDLVEISPNAEPPVCRVMDYGKFLFE
KAKAAKEQKKKQKQVQTKEIKFRPGTDIGDYQVKLRNLTGFLEEGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFA
VVESFPTRIEGRQMIMVLAPKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=183, Percent_Identity=74.8633879781421, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_ALISL (B6EN33)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263167.1
- GeneID:   6989178
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1759
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20386; Mature: 20386

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGGKRAQQPAKQNAHRLNGEIIGVKEVRLTGLDGESVGVVSLNEALDVALTAGVDLVEI
CCCCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEEECHHHHHHHHCCEEEEEE
SPNAEPPVCRVMDYGKFLFEKAKAAKEQKKKQKQVQTKEIKFRPGTDIGDYQVKLRNLTG
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEHHHH
FLEEGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFAVVESFPTRIEGRQMIMVLAP
HHCCCCEEEEEEEECCCHHHHHCCCHHHHHHHCCCHHHHEEHHHCCCCCCCCEEEEEEEC
KKK
CCC
>Mature Secondary Structure
MKGGKRAQQPAKQNAHRLNGEIIGVKEVRLTGLDGESVGVVSLNEALDVALTAGVDLVEI
CCCCCCCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCEEEEEECHHHHHHHHCCEEEEEE
SPNAEPPVCRVMDYGKFLFEKAKAAKEQKKKQKQVQTKEIKFRPGTDIGDYQVKLRNLTG
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEEHHHH
FLEEGNKVKVTIRFRGREMAHQNIGVDVLNRLKADTEEFAVVESFPTRIEGRQMIMVLAP
HHCCCCEEEEEEEECCCHHHHHCCCHHHHHHHCCCHHHHEEHHHCCCCCCCCEEEEEEEC
KKK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA