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The map label for this gene is int [H]

Identifier: 209695207

GI number: 209695207

Start: 1830387

End: 1831628

Strand: Reverse

Name: int [H]

Synonym: VSAL_I1721

Alternate gene names: 209695207

Gene position: 1831628-1830387 (Counterclockwise)

Preceding gene: 209695208

Following gene: 209695205

Centisome position: 55.08

GC content: 38.33

Gene sequence:

>1242_bases
ATGGCTATAAAAGTACAGCCCTTAACGGCGACCCAAGTTAAACAAGCAAAACCAAAAGATAAAGAATATAACCTAGGTGA
TGGTGATGGTTTATCTTTAAAGGTAAAACCAATAGGCACTAAGTTATGGCGCTTTTCTTATTATCATCCAATAACAAGAA
AACGCCTTAATTTAGCTTTAGGTAAATATCCAGATATCTCACTTGCTAAAGCAAGAAGTAAAGCAATTGAAGCCAGAGAG
ATACTTGCCGACGGTATTGATCCGAAAGAGCATCGAGATAATACACTTCGTGAAAAACAACTAGAGTTATCTAATACCTT
ACAAGCGGTATTTGATGACTGGCTTGAAGTAAAGAAAACAAGTATTAAAGAACAAACAGCTAAGAAATTAAAACAACGAA
TAGAGAAGTACCTTTTACCTGATCTTGGTAAACTCCCGCTTGGTGACATTACCGCTCCACAAGCCATAAAAACCATTAAG
CCAATTGCGAACCAAGGTAAGTTAGAAACGGTAGGGCGATTGTGTCGTAATTTAAACGAGATCATGACGTTTGCGGTGAA
CACTGGCGTTATCGAACATAATAGACTTGCTGGTATTGGGAAAGCGTTTGAAACTGCAAAAGTTACTAACCAGGCATCGC
TAGATCCTAAAGATCTACCAGAACTGTTAAAAACGATTAATTACGCATCTATTAAGCCTATCACACGCTGTTTGTTAGAA
TGGCAACTTCATACAATGACAAGACCAGCCGAGACTGCTGGTGCGCGCTGGAATGAAATAGACAAAGAAAAAATGCTTTG
GGTTATCCCTGCTGAACGAATGAAGAAGGGAAGAGTACATACCGTCCCATTAACAAAGCAAACATTAGATTTATTAGAAA
CGATTGATTTTATTACAGGTGAGAGTGAATACCTTTTCCCTGCTGATAAAAGTAATAAAAATCACATAAATAAAGAAACA
GCTAATAAAGCATTGGTTCGAATGGGATTTAAGGGAAGACAAACTTCTCATGGCCTACGAGCATTAGCTAGTACTACCTT
AAATGAACAAAACTTCGATTCGGATATTATTGAAGCAGCACTTTCTCACGTTGATAGAGATAAGGTTCGAAGTGCTTATA
ATCGCACAGACTACCTTGAACGACGTAAGGTTCTAATGGCGTGGTGGAGCAATCATATTGAAGAGGCAGCTACTGGTAGT
TTGTCTATGAGTGGGAAAAAGAGTCTTAAGGCTGTAGGTTAG

Upstream 100 bases:

>100_bases
GTAAGCGTCCATTAGTGTCTTGTAAAATCCACGGTTTGAAGTAATCTCTGAAGTAACCTTTTTAAAATTGTGTGCTTTCG
AGGTTACTTCAGAGGTTCAA

Downstream 100 bases:

>100_bases
TTTTAAAGTTGTAGATCTTTTAATATATTTATGATTAGTGTCATTTCTATAGTTAAATTTGCTATGAAGTGACACTCTCT
TTTAAAAAGATATTAAGACA

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MAIKVQPLTATQVKQAKPKDKEYNLGDGDGLSLKVKPIGTKLWRFSYYHPITRKRLNLALGKYPDISLAKARSKAIEARE
ILADGIDPKEHRDNTLREKQLELSNTLQAVFDDWLEVKKTSIKEQTAKKLKQRIEKYLLPDLGKLPLGDITAPQAIKTIK
PIANQGKLETVGRLCRNLNEIMTFAVNTGVIEHNRLAGIGKAFETAKVTNQASLDPKDLPELLKTINYASIKPITRCLLE
WQLHTMTRPAETAGARWNEIDKEKMLWVIPAERMKKGRVHTVPLTKQTLDLLETIDFITGESEYLFPADKSNKNHINKET
ANKALVRMGFKGRQTSHGLRALASTTLNEQNFDSDIIEAALSHVDRDKVRSAYNRTDYLERRKVLMAWWSNHIEEAATGS
LSMSGKKSLKAVG

Sequences:

>Translated_413_residues
MAIKVQPLTATQVKQAKPKDKEYNLGDGDGLSLKVKPIGTKLWRFSYYHPITRKRLNLALGKYPDISLAKARSKAIEARE
ILADGIDPKEHRDNTLREKQLELSNTLQAVFDDWLEVKKTSIKEQTAKKLKQRIEKYLLPDLGKLPLGDITAPQAIKTIK
PIANQGKLETVGRLCRNLNEIMTFAVNTGVIEHNRLAGIGKAFETAKVTNQASLDPKDLPELLKTINYASIKPITRCLLE
WQLHTMTRPAETAGARWNEIDKEKMLWVIPAERMKKGRVHTVPLTKQTLDLLETIDFITGESEYLFPADKSNKNHINKET
ANKALVRMGFKGRQTSHGLRALASTTLNEQNFDSDIIEAALSHVDRDKVRSAYNRTDYLERRKVLMAWWSNHIEEAATGS
LSMSGKKSLKAVG
>Mature_412_residues
AIKVQPLTATQVKQAKPKDKEYNLGDGDGLSLKVKPIGTKLWRFSYYHPITRKRLNLALGKYPDISLAKARSKAIEAREI
LADGIDPKEHRDNTLREKQLELSNTLQAVFDDWLEVKKTSIKEQTAKKLKQRIEKYLLPDLGKLPLGDITAPQAIKTIKP
IANQGKLETVGRLCRNLNEIMTFAVNTGVIEHNRLAGIGKAFETAKVTNQASLDPKDLPELLKTINYASIKPITRCLLEW
QLHTMTRPAETAGARWNEIDKEKMLWVIPAERMKKGRVHTVPLTKQTLDLLETIDFITGESEYLFPADKSNKNHINKETA
NKALVRMGFKGRQTSHGLRALASTTLNEQNFDSDIIEAALSHVDRDKVRSAYNRTDYLERRKVLMAWWSNHIEEAATGSL
SMSGKKSLKAVG

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=413, Percent_Identity=45.2784503631961, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788690, Length=389, Percent_Identity=30.3341902313625, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI145693166, Length=400, Percent_Identity=32.5, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46597; Mature: 46466

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKVQPLTATQVKQAKPKDKEYNLGDGDGLSLKVKPIGTKLWRFSYYHPITRKRLNLAL
CEEEECCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHH
GKYPDISLAKARSKAIEAREILADGIDPKEHRDNTLREKQLELSNTLQAVFDDWLEVKKT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKEQTAKKLKQRIEKYLLPDLGKLPLGDITAPQAIKTIKPIANQGKLETVGRLCRNLNE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IMTFAVNTGVIEHNRLAGIGKAFETAKVTNQASLDPKDLPELLKTINYASIKPITRCLLE
HHHHHHHCCCEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
WQLHTMTRPAETAGARWNEIDKEKMLWVIPAERMKKGRVHTVPLTKQTLDLLETIDFITG
HHHHHCCCCHHHHCCCCCCCCHHHEEEEECHHHHHCCCEEECCCCHHHHHHHHHHHHHCC
ESEYLFPADKSNKNHINKETANKALVRMGFKGRQTSHGLRALASTTLNEQNFDSDIIEAA
CCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
LSHVDRDKVRSAYNRTDYLERRKVLMAWWSNHIEEAATGSLSMSGKKSLKAVG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
AIKVQPLTATQVKQAKPKDKEYNLGDGDGLSLKVKPIGTKLWRFSYYHPITRKRLNLAL
EEEECCCCHHHHHHCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHH
GKYPDISLAKARSKAIEAREILADGIDPKEHRDNTLREKQLELSNTLQAVFDDWLEVKKT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIKEQTAKKLKQRIEKYLLPDLGKLPLGDITAPQAIKTIKPIANQGKLETVGRLCRNLNE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IMTFAVNTGVIEHNRLAGIGKAFETAKVTNQASLDPKDLPELLKTINYASIKPITRCLLE
HHHHHHHCCCEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
WQLHTMTRPAETAGARWNEIDKEKMLWVIPAERMKKGRVHTVPLTKQTLDLLETIDFITG
HHHHHCCCCHHHHCCCCCCCCHHHEEEEECHHHHHCCCEEECCCCHHHHHHHHHHHHHCC
ESEYLFPADKSNKNHINKETANKALVRMGFKGRQTSHGLRALASTTLNEQNFDSDIIEAA
CCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
LSHVDRDKVRSAYNRTDYLERRKVLMAWWSNHIEEAATGSLSMSGKKSLKAVG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]