Click here to switch to the map view.

The map label for this gene is pabB [H]

Identifier: 209694875

GI number: 209694875

Start: 1461130

End: 1462500

Strand: Reverse

Name: pabB [H]

Synonym: VSAL_I1346

Alternate gene names: 209694875

Gene position: 1462500-1461130 (Counterclockwise)

Preceding gene: 209694877

Following gene: 209694874

Centisome position: 43.98

GC content: 39.97

Gene sequence:

>1371_bases
ATGAACAATCAATTAGACGCAAAATTACAAATGACATCCCTTGATTATCAATCCAACTCTTTGGTTGATTTGTTTTCTGC
AATTGAATCTCAACCATGGTCGATGTTATTGCATTCCTCTGCGGTTGCTCATGTCGATAATCGCTACGACATCGTCGTTT
CTGATCCAATAGCAACGTTACAAACTCACGATAAAATCACTTCTATTAATATAAAAGGAAGAGATCTCATAACCAGTGAG
GATTGCCCCTTTGAATTGTTAGCTCACTATCAAGAATCCCTAACACCAAGCTGCGATTCCATCACTGATCTTCCTTTTAT
TGGCGGCGCTTTAGGCTACTTTAGTTATGATCTAGGCCGCCGAGTTGAATCGATACCTAATATTTCAGAAAAAGACATCC
CCACCGCAGAGATGGCGATAGGGATTTATGATTGGGCACTGGTTGCTGATCATAAAAAGAAAACATTAACGTTAATTCAG
CCAAACAACAGTGATCGCCTAGCATGGTTGCAACCGTTCACCGCCATTCAAGAAGAGAAACTGTCGTTCCAATTAACGAC
ACCTTGGTCATCAAACATGACAAAAATTGAATACTCTGAAAAATTTGACGTTATTTCTGAGTATCTTCAATCCGGTGATT
GCTACCAGATAAATCTTGCCCAGCGCTTTAGTGCACACTATGAAGGTTCTGAATGGTTGGCTTATCAAAAACTCGCGATA
AATAACGGAGCCCCTTTTTCGGCGTTCATTAGAACACCTGAATTAACCATTATTTCCGTATCGCCTGAACGTTTTTTACA
CGTTAAAGACAAGCAGATAGAAACCAAACCAATCAAAGGCACTCGTCCTCGCTCAAAAGATCCAGTAATAGATGCGAAAG
AAGCTGAAATATTACGTAATAGCGCAAAAGATCGCTCAGAGAACTTAATGATTGTGGATTTATTACGTAACGATATTGGT
CGAGTAGCAAAACCGGGATCGGTGAACGTACCGAGCCTCTTTGCGATTGAATCATTTCCTGCTGTCCATCACCTCGTTAG
CACTATCACAGGTGAACTTAATACTGGTTACAGCGCTTTTGATTTATTAAAAGCCTCTTTTCCTGGAGGCTCTATCACTG
GAGCACCAAAAATTAGAGCAATGGAAATTATTGAAGAGTTAGAACCACATCGTCGTAATTTATATTGTGGCAGTATTGGT
TATATCAGTCGCTGTGGTGCGATGGACACCAGTATTACCATTCGAACATTAATCGCTTATGACGATACTTTATACGCTTC
CGCTGGCGGTGGCATTGTTGCAGATAGCGAAGTTGAACTAGAATATGAAGAGACATTACATAAGTTAAGTAAAATTCTAC
CGATATTATAA

Upstream 100 bases:

>100_bases
ATCGTCATCTATTATTTTCTTTTAGAACTCTCAGTATGATACTCTTGCTCTCTATTCAAGGCTATCGTTGCTCATCACAT
TCTGGTCATAAAAACTCAAA

Downstream 100 bases:

>100_bases
TGTCACTTAAACTAAGGATCCGGCTTATGGATACACATTTATTGTCTCATTTATTACTCAATAAGCCGAATTCATACAGT
GAAGATTTATTGCTGCACCC

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNNQLDAKLQMTSLDYQSNSLVDLFSAIESQPWSMLLHSSAVAHVDNRYDIVVSDPIATLQTHDKITSINIKGRDLITSE
DCPFELLAHYQESLTPSCDSITDLPFIGGALGYFSYDLGRRVESIPNISEKDIPTAEMAIGIYDWALVADHKKKTLTLIQ
PNNSDRLAWLQPFTAIQEEKLSFQLTTPWSSNMTKIEYSEKFDVISEYLQSGDCYQINLAQRFSAHYEGSEWLAYQKLAI
NNGAPFSAFIRTPELTIISVSPERFLHVKDKQIETKPIKGTRPRSKDPVIDAKEAEILRNSAKDRSENLMIVDLLRNDIG
RVAKPGSVNVPSLFAIESFPAVHHLVSTITGELNTGYSAFDLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIG
YISRCGAMDTSITIRTLIAYDDTLYASAGGGIVADSEVELEYEETLHKLSKILPIL

Sequences:

>Translated_456_residues
MNNQLDAKLQMTSLDYQSNSLVDLFSAIESQPWSMLLHSSAVAHVDNRYDIVVSDPIATLQTHDKITSINIKGRDLITSE
DCPFELLAHYQESLTPSCDSITDLPFIGGALGYFSYDLGRRVESIPNISEKDIPTAEMAIGIYDWALVADHKKKTLTLIQ
PNNSDRLAWLQPFTAIQEEKLSFQLTTPWSSNMTKIEYSEKFDVISEYLQSGDCYQINLAQRFSAHYEGSEWLAYQKLAI
NNGAPFSAFIRTPELTIISVSPERFLHVKDKQIETKPIKGTRPRSKDPVIDAKEAEILRNSAKDRSENLMIVDLLRNDIG
RVAKPGSVNVPSLFAIESFPAVHHLVSTITGELNTGYSAFDLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIG
YISRCGAMDTSITIRTLIAYDDTLYASAGGGIVADSEVELEYEETLHKLSKILPIL
>Mature_456_residues
MNNQLDAKLQMTSLDYQSNSLVDLFSAIESQPWSMLLHSSAVAHVDNRYDIVVSDPIATLQTHDKITSINIKGRDLITSE
DCPFELLAHYQESLTPSCDSITDLPFIGGALGYFSYDLGRRVESIPNISEKDIPTAEMAIGIYDWALVADHKKKTLTLIQ
PNNSDRLAWLQPFTAIQEEKLSFQLTTPWSSNMTKIEYSEKFDVISEYLQSGDCYQINLAQRFSAHYEGSEWLAYQKLAI
NNGAPFSAFIRTPELTIISVSPERFLHVKDKQIETKPIKGTRPRSKDPVIDAKEAEILRNSAKDRSENLMIVDLLRNDIG
RVAKPGSVNVPSLFAIESFPAVHHLVSTITGELNTGYSAFDLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIG
YISRCGAMDTSITIRTLIAYDDTLYASAGGGIVADSEVELEYEETLHKLSKILPIL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=435, Percent_Identity=56.551724137931, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1787518, Length=368, Percent_Identity=32.6086956521739, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786809, Length=200, Percent_Identity=28, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87082077, Length=267, Percent_Identity=23.2209737827715, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=415, Percent_Identity=31.8072289156626, Blast_Score=189, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=401, Percent_Identity=28.428927680798, Blast_Score=146, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50802; Mature: 50802

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQLDAKLQMTSLDYQSNSLVDLFSAIESQPWSMLLHSSAVAHVDNRYDIVVSDPIATL
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHH
QTHDKITSINIKGRDLITSEDCPFELLAHYQESLTPSCDSITDLPFIGGALGYFSYDLGR
CCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVESIPNISEKDIPTAEMAIGIYDWALVADHKKKTLTLIQPNNSDRLAWLQPFTAIQEEK
HHHHCCCCCCCCCCHHHHEEEEEHEEEEECCCCCEEEEECCCCCCCEEEECHHHHHHHCC
LSFQLTTPWSSNMTKIEYSEKFDVISEYLQSGDCYQINLAQRFSAHYEGSEWLAYQKLAI
CEEEEECCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCEEEEEEEEE
NNGAPFSAFIRTPELTIISVSPERFLHVKDKQIETKPIKGTRPRSKDPVIDAKEAEILRN
CCCCCCEEEEECCCEEEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SAKDRSENLMIVDLLRNDIGRVAKPGSVNVPSLFAIESFPAVHHLVSTITGELNTGYSAF
HCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHH
DLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIGYISRCGAMDTSITIRTLIAY
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHCCEEECCCHHHHHCCCCCCCEEEEEEEEE
DDTLYASAGGGIVADSEVELEYEETLHKLSKILPIL
CCEEEEECCCCEEECCEEEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNQLDAKLQMTSLDYQSNSLVDLFSAIESQPWSMLLHSSAVAHVDNRYDIVVSDPIATL
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHH
QTHDKITSINIKGRDLITSEDCPFELLAHYQESLTPSCDSITDLPFIGGALGYFSYDLGR
CCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVESIPNISEKDIPTAEMAIGIYDWALVADHKKKTLTLIQPNNSDRLAWLQPFTAIQEEK
HHHHCCCCCCCCCCHHHHEEEEEHEEEEECCCCCEEEEECCCCCCCEEEECHHHHHHHCC
LSFQLTTPWSSNMTKIEYSEKFDVISEYLQSGDCYQINLAQRFSAHYEGSEWLAYQKLAI
CEEEEECCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCEEEEEEEEE
NNGAPFSAFIRTPELTIISVSPERFLHVKDKQIETKPIKGTRPRSKDPVIDAKEAEILRN
CCCCCCEEEEECCCEEEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SAKDRSENLMIVDLLRNDIGRVAKPGSVNVPSLFAIESFPAVHHLVSTITGELNTGYSAF
HCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCHHH
DLLKASFPGGSITGAPKIRAMEIIEELEPHRRNLYCGSIGYISRCGAMDTSITIRTLIAY
HHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHCCEEECCCHHHHHCCCCCCCEEEEEEEEE
DDTLYASAGGGIVADSEVELEYEETLHKLSKILPIL
CCEEEEECCCCEEECCEEEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]