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The map label for this gene is ttdR [H]

Identifier: 209694777

GI number: 209694777

Start: 1343523

End: 1344458

Strand: Direct

Name: ttdR [H]

Synonym: VSAL_I1233

Alternate gene names: 209694777

Gene position: 1343523-1344458 (Clockwise)

Preceding gene: 209694775

Following gene: 209694778

Centisome position: 40.4

GC content: 43.38

Gene sequence:

>936_bases
ATGCATGATCGTGCCAGCCAAATGGTGATATTTTACGCCCTAGCCAAAGCGGGAAGCTTTACTGCTGCCGCAAAACAAAT
GGGCGTATCTACCTCTCATGTGAGTAAACAGCTGGGAATATTAGAAGCAGAGCTTAACGTTAAGTTAGTACAGCGCACGA
CACGCTCGTTAACACTGACTGATGCAGGGCAACAGTTCTATTTGTATTGTGAAAAGATGTACAGTGCGATGACAGAAGCC
AGTGCAATTATGGATAATGAACGTGATGAGGTCGCGGGTATCTTGCGTTTAGGGTTATCACAGTCTTTTGGTACCATGCA
CATTATCCCAGCGATAGATAAATTACGTCACCAATATCCAGATCTTCAGGTCGAAGTTCGTTTGTTCGATCATCGTGCTG
ATATGCTTAAAGACGGTCTAGATCTCTGGGTAACCAACTTTGAAGACTTACCAGAAGGTTACGTTGCACAGCGATTAGCG
GATTCGCATTTTGTATTGGCAGCATCACCTGATTATTTGATTGATAAAGCGGTTCCTCATCATCCTCAAGATCTCACTGA
GCACAATTGCTTAACGTACCAAAGCCGTCACCGTGACTACAGTAATTGGGATTTCAGTAAAGGTAATGAAGCATTGTGTG
TGAAGGTATCTGGTAATTACTGTGTCGATTTAGCTGAAGCGGTAAGAGATGCCGCGATTTCAGGATGGGGCGTGGCGTAT
TTAGCCAGTTACTTACTTACCAATGAGTTTAATGATGGCAAATTGATTCAGCTTTTACCCGACTGGAAAGCGAGTCAAAA
AATGCCAATTTACGCGGTTTACCCAAGCCGTAAACACCTGCCAAGAAAGATAAGTGCGGTGATTGATTTTTTACGAGAGC
ACATTGGACAACCGCCATATTGGGACAAAACGCTAATGAAACGGGTTAAGTTATAA

Upstream 100 bases:

>100_bases
CATGAGCGTAATTAATACTTATAAGGTTATTTTACTTAATAGACTAAGTAGATGTTATTATCTGCCGCCCAGATCCCCTT
TGAGTTAAAGGACAAGAGAG

Downstream 100 bases:

>100_bases
TCAACGTTTGATGCGTTCAATATTGTCATTGATTAAATAAAACACAGCGCAATGATGTCTTTTTAATCAATGACTTAAAT
CTATTATCAGTCTTGAAATA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MHDRASQMVIFYALAKAGSFTAAAKQMGVSTSHVSKQLGILEAELNVKLVQRTTRSLTLTDAGQQFYLYCEKMYSAMTEA
SAIMDNERDEVAGILRLGLSQSFGTMHIIPAIDKLRHQYPDLQVEVRLFDHRADMLKDGLDLWVTNFEDLPEGYVAQRLA
DSHFVLAASPDYLIDKAVPHHPQDLTEHNCLTYQSRHRDYSNWDFSKGNEALCVKVSGNYCVDLAEAVRDAAISGWGVAY
LASYLLTNEFNDGKLIQLLPDWKASQKMPIYAVYPSRKHLPRKISAVIDFLREHIGQPPYWDKTLMKRVKL

Sequences:

>Translated_311_residues
MHDRASQMVIFYALAKAGSFTAAAKQMGVSTSHVSKQLGILEAELNVKLVQRTTRSLTLTDAGQQFYLYCEKMYSAMTEA
SAIMDNERDEVAGILRLGLSQSFGTMHIIPAIDKLRHQYPDLQVEVRLFDHRADMLKDGLDLWVTNFEDLPEGYVAQRLA
DSHFVLAASPDYLIDKAVPHHPQDLTEHNCLTYQSRHRDYSNWDFSKGNEALCVKVSGNYCVDLAEAVRDAAISGWGVAY
LASYLLTNEFNDGKLIQLLPDWKASQKMPIYAVYPSRKHLPRKISAVIDFLREHIGQPPYWDKTLMKRVKL
>Mature_311_residues
MHDRASQMVIFYALAKAGSFTAAAKQMGVSTSHVSKQLGILEAELNVKLVQRTTRSLTLTDAGQQFYLYCEKMYSAMTEA
SAIMDNERDEVAGILRLGLSQSFGTMHIIPAIDKLRHQYPDLQVEVRLFDHRADMLKDGLDLWVTNFEDLPEGYVAQRLA
DSHFVLAASPDYLIDKAVPHHPQDLTEHNCLTYQSRHRDYSNWDFSKGNEALCVKVSGNYCVDLAEAVRDAAISGWGVAY
LASYLLTNEFNDGKLIQLLPDWKASQKMPIYAVYPSRKHLPRKISAVIDFLREHIGQPPYWDKTLMKRVKL

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=301, Percent_Identity=31.2292358803987, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=28.4722222222222, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786401, Length=299, Percent_Identity=27.4247491638796, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=29.1095890410959, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787128, Length=297, Percent_Identity=27.2727272727273, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=27.1477663230241, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=24.4827586206897, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789173, Length=247, Percent_Identity=28.7449392712551, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788706, Length=297, Percent_Identity=24.9158249158249, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786448, Length=273, Percent_Identity=24.5421245421245, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=177, Percent_Identity=28.2485875706215, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790011, Length=299, Percent_Identity=22.4080267558528, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=35, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=137, Percent_Identity=29.9270072992701, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=173, Percent_Identity=24.2774566473988, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35273; Mature: 35273

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDRASQMVIFYALAKAGSFTAAAKQMGVSTSHVSKQLGILEAELNVKLVQRTTRSLTLT
CCCCHHHEEHEEEHHHCCCHHHHHHHHCCCHHHHHHHHCEEEHHCCHHHHHHHHHEEEEE
DAGQQFYLYCEKMYSAMTEASAIMDNERDEVAGILRLGLSQSFGTMHIIPAIDKLRHQYP
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCC
DLQVEVRLFDHRADMLKDGLDLWVTNFEDLPEGYVAQRLADSHFVLAASPDYLIDKAVPH
CCEEEEEEEHHHHHHHHCCHHEEECCHHHCCHHHHHHHHCCCCEEEEECCCHHHHCCCCC
HPQDLTEHNCLTYQSRHRDYSNWDFSKGNEALCVKVSGNYCVDLAEAVRDAAISGWGVAY
CCCHHCCCCCEEEHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCHHH
LASYLLTNEFNDGKLIQLLPDWKASQKMPIYAVYPSRKHLPRKISAVIDFLREHIGQPPY
HHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
WDKTLMKRVKL
CCHHHHHHHCC
>Mature Secondary Structure
MHDRASQMVIFYALAKAGSFTAAAKQMGVSTSHVSKQLGILEAELNVKLVQRTTRSLTLT
CCCCHHHEEHEEEHHHCCCHHHHHHHHCCCHHHHHHHHCEEEHHCCHHHHHHHHHEEEEE
DAGQQFYLYCEKMYSAMTEASAIMDNERDEVAGILRLGLSQSFGTMHIIPAIDKLRHQYP
CCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCC
DLQVEVRLFDHRADMLKDGLDLWVTNFEDLPEGYVAQRLADSHFVLAASPDYLIDKAVPH
CCEEEEEEEHHHHHHHHCCHHEEECCHHHCCHHHHHHHHCCCCEEEEECCCHHHHCCCCC
HPQDLTEHNCLTYQSRHRDYSNWDFSKGNEALCVKVSGNYCVDLAEAVRDAAISGWGVAY
CCCHHCCCCCEEEHHHCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCHHH
LASYLLTNEFNDGKLIQLLPDWKASQKMPIYAVYPSRKHLPRKISAVIDFLREHIGQPPY
HHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
WDKTLMKRVKL
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]