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The map label for this gene is yhcS [C]

Identifier: 209694745

GI number: 209694745

Start: 1308200

End: 1309102

Strand: Reverse

Name: yhcS [C]

Synonym: VSAL_I1199

Alternate gene names: 209694745

Gene position: 1309102-1308200 (Counterclockwise)

Preceding gene: 209694749

Following gene: 209694741

Centisome position: 39.37

GC content: 40.64

Gene sequence:

>903_bases
ATGGGTCAGCTAGAAAGTATGCACATTTTTACCAAGGTGGTAGAAGCAGGAGGAATAACAAAAGCGGCGGAACAGTTAAA
TTTGGCGAAATCGGCCGTCAGTAAACGACTGAGTGAATTAGAGCAACAACTTGGTATTAAGCTCATCAATCGAACGACTC
GTACTTCTAGTCTTACCGAAGCAGGGCAATCTTATTTCATAAAATGTAAATTAATACTTGAGGAAGTAAACGATCTTAAC
TGCCATGTGTCAGCCATTCATCAAGAATTAAATGGCACCATAAAACTCGCCGTTCCCCTCACCTTTGGTGTGATGCATTT
GGTTCCTGCCTTAGATGATTTTGCAAAAGCACACCCTAAATTGAAACTGGATATTGATTTCTCTGATCGCAAAGTCGATT
TGGTTGAAGAAGGTATCGATTTAGCGATTCGTATTGGTAATCTCACAAGCTCAACACTGCAAGCTAAAGCCATTGCCCCT
ATTCATCACGTGTTATGTGCAAGTCCTGCTTATTTAGCTGAACATGGCAATCCATCCACTCCTGACGCACTTAAATCACA
TCAGCTATTAAGATACCGTCAACAGCCTTTATCTGGTGTTGAATTACGTGATAATAAAAATCAAGCGATGACGGTTCCAA
TGGAAACACATTGTATTGCGAATAATGGAGACTTCTTAAAAGCGATGGCGGTCTCTGGGCATGGGATTATTTTTATGCCG
ACCTTTATTGTTTGGGAGGAGCTTGCGAAGGGAACGTTGCTGCCTATCATGAACGATTATCACTTCAACTCAGTACACGC
TTATGCTCTTTATCCTGAAACCCGATATCTTCCTCAAAAAGTACGTAAATTGATCGACTTTTTAAGTGCTTATTTTGGGA
ATGAGCCTTATTGGGATAAGTAA

Upstream 100 bases:

>100_bases
GCTTGGTGTAAAGAATAGTCGTTGAACAAAAGTAGATAAACAGCAATACTGAGGAAACACTGTTCTCATATAAAGAACAA
TAGATAAATAAGGGGCAGTC

Downstream 100 bases:

>100_bases
ATTTATGCGAAAGAAAGTTGCAATATCCGTATCGTAGAACCGAATATTGCAACTGTGTTATTTTAGTATAAGACCATGGT
TAGGTAACCTAAAACCAGTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MGQLESMHIFTKVVEAGGITKAAEQLNLAKSAVSKRLSELEQQLGIKLINRTTRTSSLTEAGQSYFIKCKLILEEVNDLN
CHVSAIHQELNGTIKLAVPLTFGVMHLVPALDDFAKAHPKLKLDIDFSDRKVDLVEEGIDLAIRIGNLTSSTLQAKAIAP
IHHVLCASPAYLAEHGNPSTPDALKSHQLLRYRQQPLSGVELRDNKNQAMTVPMETHCIANNGDFLKAMAVSGHGIIFMP
TFIVWEELAKGTLLPIMNDYHFNSVHAYALYPETRYLPQKVRKLIDFLSAYFGNEPYWDK

Sequences:

>Translated_300_residues
MGQLESMHIFTKVVEAGGITKAAEQLNLAKSAVSKRLSELEQQLGIKLINRTTRTSSLTEAGQSYFIKCKLILEEVNDLN
CHVSAIHQELNGTIKLAVPLTFGVMHLVPALDDFAKAHPKLKLDIDFSDRKVDLVEEGIDLAIRIGNLTSSTLQAKAIAP
IHHVLCASPAYLAEHGNPSTPDALKSHQLLRYRQQPLSGVELRDNKNQAMTVPMETHCIANNGDFLKAMAVSGHGIIFMP
TFIVWEELAKGTLLPIMNDYHFNSVHAYALYPETRYLPQKVRKLIDFLSAYFGNEPYWDK
>Mature_299_residues
GQLESMHIFTKVVEAGGITKAAEQLNLAKSAVSKRLSELEQQLGIKLINRTTRTSSLTEAGQSYFIKCKLILEEVNDLNC
HVSAIHQELNGTIKLAVPLTFGVMHLVPALDDFAKAHPKLKLDIDFSDRKVDLVEEGIDLAIRIGNLTSSTLQAKAIAPI
HHVLCASPAYLAEHGNPSTPDALKSHQLLRYRQQPLSGVELRDNKNQAMTVPMETHCIANNGDFLKAMAVSGHGIIFMPT
FIVWEELAKGTLLPIMNDYHFNSVHAYALYPETRYLPQKVRKLIDFLSAYFGNEPYWDK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=32.5342465753425, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=33.1081081081081, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=29.9319727891156, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=32.5342465753425, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=28.125, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787128, Length=280, Percent_Identity=25.7142857142857, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=25.5172413793103, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788706, Length=266, Percent_Identity=30.4511278195489, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789173, Length=259, Percent_Identity=27.4131274131274, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790011, Length=300, Percent_Identity=22.6666666666667, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=27.8688524590164, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=123, Percent_Identity=27.6422764227642, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=21.4532871972318, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33431; Mature: 33300

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQLESMHIFTKVVEAGGITKAAEQLNLAKSAVSKRLSELEQQLGIKLINRTTRTSSLTE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHH
AGQSYFIKCKLILEEVNDLNCHVSAIHQELNGTIKLAVPLTFGVMHLVPALDDFAKAHPK
CCHHEEEEHEEEEHHHCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHCCCC
LKLDIDFSDRKVDLVEEGIDLAIRIGNLTSSTLQAKAIAPIHHVLCASPAYLAEHGNPST
EEEEECCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
PDALKSHQLLRYRQQPLSGVELRDNKNQAMTVPMETHCIANNGDFLKAMAVSGHGIIFMP
CHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCHHEEEECCCCEEEEEEECCCCEEEHH
TFIVWEELAKGTLLPIMNDYHFNSVHAYALYPETRYLPQKVRKLIDFLSAYFGNEPYWDK
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GQLESMHIFTKVVEAGGITKAAEQLNLAKSAVSKRLSELEQQLGIKLINRTTRTSSLTE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHH
AGQSYFIKCKLILEEVNDLNCHVSAIHQELNGTIKLAVPLTFGVMHLVPALDDFAKAHPK
CCHHEEEEHEEEEHHHCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHCCCC
LKLDIDFSDRKVDLVEEGIDLAIRIGNLTSSTLQAKAIAPIHHVLCASPAYLAEHGNPST
EEEEECCCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCC
PDALKSHQLLRYRQQPLSGVELRDNKNQAMTVPMETHCIANNGDFLKAMAVSGHGIIFMP
CHHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCHHEEEECCCCEEEEEEECCCCEEEHH
TFIVWEELAKGTLLPIMNDYHFNSVHAYALYPETRYLPQKVRKLIDFLSAYFGNEPYWDK
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]