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The map label for this gene is ycgM [H]

Identifier: 209694736

GI number: 209694736

Start: 1296672

End: 1297286

Strand: Reverse

Name: ycgM [H]

Synonym: VSAL_I1190

Alternate gene names: 209694736

Gene position: 1297286-1296672 (Counterclockwise)

Preceding gene: 209694738

Following gene: 209694732

Centisome position: 39.01

GC content: 39.51

Gene sequence:

>615_bases
ATGAACACGATTCGTATTGGAGAAAAACGAATTACACCAAGTAAATTGTTATGCGTTGGCCGGAATTATCATGCTCATAT
CAATGAACTAAACAATGCGGTTCCTGAGCAAATGGTCGTGTTCAATAAACCCAATTCTTGCATTAGCTCTACGCTGTCTT
CTTTTCACCAAGAAACATTACATTATGAAGCTGAAATCTGTTTTTTAATCGAGAATGGACAACTGTCTGCAGTGGCTGTT
GGGCTTGATCTAACTAAGCGTGAGTTACAATCTTATCTAAAAAAGAAAGGATTACCGTGGGAAAGAGCAAAAGCGTTCAA
TGGCTCAGCCCTATTTAGTCGCTTTATTCCCTTAGACACGATTGATATTAATGCACTTCAAATTGAACTGTTTATAAATA
GCATGCGCGTACAATGCGGCAACGTAAGCCAAATGATTTATTCTCCAGAAGCCATCCTTACAGACCTACAAAGTTATACT
CAATTATATGATGGAGATGTGATCATGAGTGGAACGCCACAAGGCGTAGGCGAAATCCACTGCGGTGATATTTTTCTTAG
TCGCTTAAAATCAGGCGATAAAACCCTAATAGAAACGGAATGGGTCGCAAGGTAG

Upstream 100 bases:

>100_bases
AGCTAGAGATCTAATTTTGGACAAAAACTCGACAGAATTAAATGTAAGCATAACAAGATCAGGTAAACTCTGCCTCCTCA
CTTCTACCAAGGATAGGAAA

Downstream 100 bases:

>100_bases
CCTTACCCTATAAATACCCATAAATTCAGCACTAGAAACACCACCATGCTTACAATGGTCGTCAATAATACATTCTTAGT
TTTCCATGCGATTACTGCCG

Product: fumarylacetoacetate hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MNTIRIGEKRITPSKLLCVGRNYHAHINELNNAVPEQMVVFNKPNSCISSTLSSFHQETLHYEAEICFLIENGQLSAVAV
GLDLTKRELQSYLKKKGLPWERAKAFNGSALFSRFIPLDTIDINALQIELFINSMRVQCGNVSQMIYSPEAILTDLQSYT
QLYDGDVIMSGTPQGVGEIHCGDIFLSRLKSGDKTLIETEWVAR

Sequences:

>Translated_204_residues
MNTIRIGEKRITPSKLLCVGRNYHAHINELNNAVPEQMVVFNKPNSCISSTLSSFHQETLHYEAEICFLIENGQLSAVAV
GLDLTKRELQSYLKKKGLPWERAKAFNGSALFSRFIPLDTIDINALQIELFINSMRVQCGNVSQMIYSPEAILTDLQSYT
QLYDGDVIMSGTPQGVGEIHCGDIFLSRLKSGDKTLIETEWVAR
>Mature_204_residues
MNTIRIGEKRITPSKLLCVGRNYHAHINELNNAVPEQMVVFNKPNSCISSTLSSFHQETLHYEAEICFLIENGQLSAVAV
GLDLTKRELQSYLKKKGLPWERAKAFNGSALFSRFIPLDTIDINALQIELFINSMRVQCGNVSQMIYSPEAILTDLQSYT
QLYDGDVIMSGTPQGVGEIHCGDIFLSRLKSGDKTLIETEWVAR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI215422413, Length=184, Percent_Identity=34.7826086956522, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI13654274, Length=184, Percent_Identity=34.7826086956522, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI66348062, Length=184, Percent_Identity=34.7826086956522, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI156231349, Length=209, Percent_Identity=28.7081339712919, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40786394, Length=209, Percent_Identity=27.7511961722488, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1787428, Length=189, Percent_Identity=37.037037037037, Blast_Score=115, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=34.0425531914894, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6324161, Length=217, Percent_Identity=31.7972350230415, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 22884; Mature: 22884

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIRIGEKRITPSKLLCVGRNYHAHINELNNAVPEQMVVFNKPNSCISSTLSSFHQETL
CCCEECCCCCCCHHHEEEECCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
HYEAEICFLIENGQLSAVAVGLDLTKRELQSYLKKKGLPWERAKAFNGSALFSRFIPLDT
EEEEEEEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHCCCCCE
IDINALQIELFINSMRVQCGNVSQMIYSPEAILTDLQSYTQLYDGDVIMSGTPQGVGEIH
ECCCEEEEEEEEEHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEE
CGDIFLSRLKSGDKTLIETEWVAR
HHHHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure
MNTIRIGEKRITPSKLLCVGRNYHAHINELNNAVPEQMVVFNKPNSCISSTLSSFHQETL
CCCEECCCCCCCHHHEEEECCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
HYEAEICFLIENGQLSAVAVGLDLTKRELQSYLKKKGLPWERAKAFNGSALFSRFIPLDT
EEEEEEEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHCCCCCE
IDINALQIELFINSMRVQCGNVSQMIYSPEAILTDLQSYTQLYDGDVIMSGTPQGVGEIH
ECCCEEEEEEEEEHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEE
CGDIFLSRLKSGDKTLIETEWVAR
HHHHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]