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The map label for this gene is sohB [H]

Identifier: 209694710

GI number: 209694710

Start: 1264620

End: 1265681

Strand: Direct

Name: sohB [H]

Synonym: VSAL_I1161

Alternate gene names: 209694710

Gene position: 1264620-1265681 (Clockwise)

Preceding gene: 209694708

Following gene: 209694712

Centisome position: 38.03

GC content: 40.96

Gene sequence:

>1062_bases
TTGGAATTTTTGTTTGATTACGGTCTCTTTTTAGCAAAGATAGCAACAGTGGTTGTTTCTATTATTGCCATCTTGGTGGC
AGCTAAAGCCGTTAGTGGAAAATCGACTGGCGCAAAAGGTGAACTAGAAGTCACTAATCTGACTGAGCAATATAAAGAGA
CGGTGGCCGATTTAGAATATCATTTGTTTGATGACGCAGAATTAAAAGCGCGTGATAAAGCAGAAAAAAAAGCGGATAAA
GAAGCCGAGAAAGCAAAACAGAAAGAAATAAAACAAGCCGCTAAAGCGGGAACATTAGAGCTTAAGCGTGATGCTCGTTT
ATTTGTTTTAGATTTTAAAGGCAGCATCGATGCAAAAGAAGTTGCGGGCCTTCGTGAAGAAGTGTCAGCAATTTTAGCGA
TTGCCGTAGAAGGGGATGAAGTGCTTCTTCGTCTTGAAAGTGGTGGGGGGATGGTTCATGGTTATGGCCTTGCTTCATCA
CAATTAGATCGTCTACGTGATGCGAATATTACGCTGACTATTTCAGTGGATAAAGTTGCCGCTTCAGGCGGTTATATGAT
GGCGTGTATCGGTGAGAAAATCATTGCTGCACCGTTCGCGATTGTGGGTTCTATTGGGGTTGTGGCGCAATTGCCTAACT
TTAGTAAGTTGTTGAAAAGAAATGATATTGAATTTGAACAACTGACCGCAGGTGAATACAAACGTACGTTAACTATGTTT
GGTGAAAACAGCGATAAAGCACGTGAGAAGTTTCAATTGGAGTTGGAAGAAACACACGTGTTATTTAAAGACTTCATTCA
TGAACATCGTGCCGATCTTGATCTTGAAAAAGTGGCGACTGGTGAGCATTGGTTTGGAAAGCAAGCGCTAGAGTTAGGTC
TCATTGATGCGATACAAACATCTGATGATTATGTAACTCAAGCATGTAAAGATCGTGAAGTATTAGCGATTCATTATGTG
CAGAAGAAAAAGTTGGGTGCAAAAATTGCGGGCATCGCAGGGCAGTCAGCTGAAAATGTCTTCATGCGAATGATTAATAT
TGGTCAACGACCGATTGTTTAA

Upstream 100 bases:

>100_bases
ATATAAAATGCGCGTTTAGTGCGATTTATTATCAATAAGATGAATTAACTTAGGGTTAAGTTAGGTACAATACACGAAAC
ATAGTTAAGAGGGTATTACA

Downstream 100 bases:

>100_bases
ATTTTTAAGCGGTAGTAATTAACGAAAAAAGGCTGAATCATTCAGCCTTTTTTATTGCCAAATTTATCGACATTATTTAA
TGGTAAATTCTTTTGATAAT

Product: periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVSGKSTGAKGELEVTNLTEQYKETVADLEYHLFDDAELKARDKAEKKADK
EAEKAKQKEIKQAAKAGTLELKRDARLFVLDFKGSIDAKEVAGLREEVSAILAIAVEGDEVLLRLESGGGMVHGYGLASS
QLDRLRDANITLTISVDKVAASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFSKLLKRNDIEFEQLTAGEYKRTLTMF
GENSDKAREKFQLELEETHVLFKDFIHEHRADLDLEKVATGEHWFGKQALELGLIDAIQTSDDYVTQACKDREVLAIHYV
QKKKLGAKIAGIAGQSAENVFMRMINIGQRPIV

Sequences:

>Translated_353_residues
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVSGKSTGAKGELEVTNLTEQYKETVADLEYHLFDDAELKARDKAEKKADK
EAEKAKQKEIKQAAKAGTLELKRDARLFVLDFKGSIDAKEVAGLREEVSAILAIAVEGDEVLLRLESGGGMVHGYGLASS
QLDRLRDANITLTISVDKVAASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFSKLLKRNDIEFEQLTAGEYKRTLTMF
GENSDKAREKFQLELEETHVLFKDFIHEHRADLDLEKVATGEHWFGKQALELGLIDAIQTSDDYVTQACKDREVLAIHYV
QKKKLGAKIAGIAGQSAENVFMRMINIGQRPIV
>Mature_353_residues
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVSGKSTGAKGELEVTNLTEQYKETVADLEYHLFDDAELKARDKAEKKADK
EAEKAKQKEIKQAAKAGTLELKRDARLFVLDFKGSIDAKEVAGLREEVSAILAIAVEGDEVLLRLESGGGMVHGYGLASS
QLDRLRDANITLTISVDKVAASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFSKLLKRNDIEFEQLTAGEYKRTLTMF
GENSDKAREKFQLELEETHVLFKDFIHEHRADLDLEKVATGEHWFGKQALELGLIDAIQTSDDYVTQACKDREVLAIHYV
QKKKLGAKIAGIAGQSAENVFMRMINIGQRPIV

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=353, Percent_Identity=53.8243626062323, Blast_Score=354, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 38752; Mature: 38752

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVSGKSTGAKGELEVTNLTEQYKETVADLEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
HLFDDAELKARDKAEKKADKEAEKAKQKEIKQAAKAGTLELKRDARLFVLDFKGSIDAKE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCHHH
VAGLREEVSAILAIAVEGDEVLLRLESGGGMVHGYGLASSQLDRLRDANITLTISVDKVA
HHHHHHHHHHHEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHCCCCEEEEEEEEEEE
ASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFSKLLKRNDIEFEQLTAGEYKRTLTMF
CCCCEEEEECCCHHHHHHHHHHHCHHHHHCCCCHHHHHHCCCCCHHHHCCHHHHHEEEEE
GENSDKAREKFQLELEETHVLFKDFIHEHRADLDLEKVATGEHWFGKQALELGLIDAIQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHCHHHHHHHHHHHHCC
SDDYVTQACKDREVLAIHYVQKKKLGAKIAGIAGQSAENVFMRMINIGQRPIV
CHHHHHHHHCCCCEEEEEEHHHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFLFDYGLFLAKIATVVVSIIAILVAAKAVSGKSTGAKGELEVTNLTEQYKETVADLEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHH
HLFDDAELKARDKAEKKADKEAEKAKQKEIKQAAKAGTLELKRDARLFVLDFKGSIDAKE
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCHHH
VAGLREEVSAILAIAVEGDEVLLRLESGGGMVHGYGLASSQLDRLRDANITLTISVDKVA
HHHHHHHHHHHEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHCCCCEEEEEEEEEEE
ASGGYMMACIGEKIIAAPFAIVGSIGVVAQLPNFSKLLKRNDIEFEQLTAGEYKRTLTMF
CCCCEEEEECCCHHHHHHHHHHHCHHHHHCCCCHHHHHHCCCCCHHHHCCHHHHHEEEEE
GENSDKAREKFQLELEETHVLFKDFIHEHRADLDLEKVATGEHWFGKQALELGLIDAIQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHCHHHHHHHHHHHHCC
SDDYVTQACKDREVLAIHYVQKKKLGAKIAGIAGQSAENVFMRMINIGQRPIV
CHHHHHHHHCCCCEEEEEEHHHHHHCCCEECCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]