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The map label for this gene is ainR [H]

Identifier: 209694706

GI number: 209694706

Start: 1258540

End: 1261008

Strand: Reverse

Name: ainR [H]

Synonym: VSAL_I1157

Alternate gene names: 209694706

Gene position: 1261008-1258540 (Counterclockwise)

Preceding gene: 209694707

Following gene: 209694703

Centisome position: 37.92

GC content: 32.52

Gene sequence:

>2469_bases
ATGCTAATTGGCTTCCCAAAAGATAAATTACTGCTATTTATCGCTGTATTCATTTTATTATGGGTAGCCTTTTTCATCCG
TTCTTTATTCAAAGAGCGGATGAAAGTTGATCCTAAAATTTACTATCCATATATAGGGTATTCTATATTCATCGTTTTTT
GGGTTCTAATAAATTACTATTTCCAATCAAATCTTTTACTTCATTTTAGTGAACGAGTTGCCACGACGATGGCTATTCTT
GCTAACTTAGCCTCTTATTTTGCCTTTGCATTTGCATTTTTGTTCTCATGTCGCCTCTCATCAACAAGAAAGAACAAAAA
GATGGCAACGTGGCAAATCATTTTATTTTATGCTGAAACTATCTTTGCAATCACGATAAATACAATTCCAAACCAAACAG
TTACAGGAGTGACCATCGTAGAGAAAGGCATTTTCACTATTCACTTTGGCCCCTTTGCTTCTTTCTTTTTTATCAATGCA
TTTCTTTTCATTGGATTAATTTTTTATAATTTTTTCAAACTAAGAAAAAGTACAATTCGATTAAATAAAGAAAAATCCAT
TTATTTACTCTTCGGAATTGTTATTTTCATGATTTCAACCATCATATCTCAAATTATCATTCCAATTATTTGGCAAGACT
TTTCATTTGCTTGGCTTCCTCCTGCGCTTTCAGTTACTGAAGCTATATTAATAGGTTACACCTTGTTATATCATCGTTTA
TATAGCCTTCGTTACCTTGCATTTTGGATATTATCTTATTCCTTAAATGCACTTATTTATTTACTGCCTTTATTTTACAT
TTATAAAGGAGCATCAGAGTCAAATTTATTATACATGAGTATTTTCTTAATCGTATTCACAGGTTTATTCTGGGAAAAAT
CCCTCAAAAGAACCAAGAAAATGTCTAGTTTACTTATATATAAAGACAGAAAAACACCTGTAGAAAAGATTTATGCCATT
GCAGAAGAATTCAAGTTTTCAAGTAATAATGCAATGGTAAAACTGGCTGAATTATTAAATACACCAAAAGAAGATCTTTT
ATTAGTTGGGAAAAATGCTAATTACAATATTTTTATCCCTCATTTAAACAAAATACATTCAGCGCTAGTAAAAGATGAGC
TCGATTATCAAATTCATTACGCTCCAGAAAAAGACAACTCTAGTCTGCATCAAGTACAAGAGAAAATGAATGAAAGCAAG
ACCGCTTTAATTTTGCCTATTTTTGGAGAAAATAAACACATCTCACATTTATTAATTTCGTCGAATAAACGAGATGGTTC
TACCTTTTCAAATGAAGAAATATCCGCCATTCAATGGGTCTTAACTAAAGTTCAAGGCTACATAGAAAGTGAACGAAAAG
TACTTCAATCACAAGCACTTGCAAACTCTATTGCTCATGAAATGCGTAATCCACTATCCCAGTTACAATACCATTTTGAA
CGCATTAAACATCACTCAAGCATAGATAAAGAAAATAAAGAGTTGATTAATAATGAGCTGAGACAAGGAAGTTTAGCGAT
TCAAAGAGGCGCTCAGTTAATTGATATCATTTTAAGTGAAGCAAAAAACACGGCTATTAATGATGAATTATTTACCCATT
ACTCTGCGGCATTATTAACCGAACGTATTGTCGATGAATACGCTTTTGATTCTGATGACATGAAAAAAAGAATTAATATC
GATCTTTCTCAAGACTTTATTTTCAACTTAAATGACACTCTATATAGTTTTATATTATTTAACTTATTAAGAAACGCAGT
TCATTACTTTAGTGAATGTAATAGCACGATATCCATCCGTTTAGTAAAAGGGTTCGCTTCAAATAAAGTGATATTTAGAG
ATACAGGCCCTGGTATAGATTCTCATATTCTACCTAATATTTTTGATGATTTTTTCACTCATAACAAAGAAGGCGGCAGT
GGTTTAGGCCTCTCTTATTGCTTACGAGTAATGCATGCCTTTGAAGGAAACATTGCCTGTTATTCTAAGAAAGGGGAATT
TACTGAATTTGTACTTAGCTTTCCTTATATTGAAGGCGATCTCACTTCTTTAATTAATCAGCAAGAGCATCATGAGTCTG
CATTGCCTTTAATTGATGTATACGATTCAGGGGATACGATAAAAACGATTCTTATTGTCGATGATAAAAAAGTGCAACGA
ATGTTAATCCAAACATTTATAGCACAAGATAATATGAATATCCTGCAAGCCGAAAATGGAGAAGAAGCAATTTCTATTGC
GATGAATCACCCATTGGATATTATTTTTATGGATTCTAGAATGCCAGTAATGAATGGTATTGATGCTGCAAAAAGAATAA
AACTCTCCTACCCAAATTTACCGATCATTGCGTTAACGGGTGAATCCGGACACGATGAAATTCAGCGTATCTCTCAAGTT
ATGGACGGTTATCTGACAAAACCAATATCAAAACCACAACTCATACAAACTCTGCACAAGTGGGTGTAA

Upstream 100 bases:

>100_bases
ATAATGCAAGTCATGCTTTTGATCAATGTAATTTCAAATCCTACAATGTTAATATCATTAGAAAAAGAAAGGAATTAAAC
AAAAGATGAGTGTTTTATAA

Downstream 100 bases:

>100_bases
TGCACATAAAAAAATAGCCAACCTCAGTTGACTATTTACTTCACGATATATCAGCCGTCTTTATTCAAACGGGCTAGGAT
CGCCAGCGCCAACACGCGCA

Product: autoinducer regulatory protein AinR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MLIGFPKDKLLLFIAVFILLWVAFFIRSLFKERMKVDPKIYYPYIGYSIFIVFWVLINYYFQSNLLLHFSERVATTMAIL
ANLASYFAFAFAFLFSCRLSSTRKNKKMATWQIILFYAETIFAITINTIPNQTVTGVTIVEKGIFTIHFGPFASFFFINA
FLFIGLIFYNFFKLRKSTIRLNKEKSIYLLFGIVIFMISTIISQIIIPIIWQDFSFAWLPPALSVTEAILIGYTLLYHRL
YSLRYLAFWILSYSLNALIYLLPLFYIYKGASESNLLYMSIFLIVFTGLFWEKSLKRTKKMSSLLIYKDRKTPVEKIYAI
AEEFKFSSNNAMVKLAELLNTPKEDLLLVGKNANYNIFIPHLNKIHSALVKDELDYQIHYAPEKDNSSLHQVQEKMNESK
TALILPIFGENKHISHLLISSNKRDGSTFSNEEISAIQWVLTKVQGYIESERKVLQSQALANSIAHEMRNPLSQLQYHFE
RIKHHSSIDKENKELINNELRQGSLAIQRGAQLIDIILSEAKNTAINDELFTHYSAALLTERIVDEYAFDSDDMKKRINI
DLSQDFIFNLNDTLYSFILFNLLRNAVHYFSECNSTISIRLVKGFASNKVIFRDTGPGIDSHILPNIFDDFFTHNKEGGS
GLGLSYCLRVMHAFEGNIACYSKKGEFTEFVLSFPYIEGDLTSLINQQEHHESALPLIDVYDSGDTIKTILIVDDKKVQR
MLIQTFIAQDNMNILQAENGEEAISIAMNHPLDIIFMDSRMPVMNGIDAAKRIKLSYPNLPIIALTGESGHDEIQRISQV
MDGYLTKPISKPQLIQTLHKWV

Sequences:

>Translated_822_residues
MLIGFPKDKLLLFIAVFILLWVAFFIRSLFKERMKVDPKIYYPYIGYSIFIVFWVLINYYFQSNLLLHFSERVATTMAIL
ANLASYFAFAFAFLFSCRLSSTRKNKKMATWQIILFYAETIFAITINTIPNQTVTGVTIVEKGIFTIHFGPFASFFFINA
FLFIGLIFYNFFKLRKSTIRLNKEKSIYLLFGIVIFMISTIISQIIIPIIWQDFSFAWLPPALSVTEAILIGYTLLYHRL
YSLRYLAFWILSYSLNALIYLLPLFYIYKGASESNLLYMSIFLIVFTGLFWEKSLKRTKKMSSLLIYKDRKTPVEKIYAI
AEEFKFSSNNAMVKLAELLNTPKEDLLLVGKNANYNIFIPHLNKIHSALVKDELDYQIHYAPEKDNSSLHQVQEKMNESK
TALILPIFGENKHISHLLISSNKRDGSTFSNEEISAIQWVLTKVQGYIESERKVLQSQALANSIAHEMRNPLSQLQYHFE
RIKHHSSIDKENKELINNELRQGSLAIQRGAQLIDIILSEAKNTAINDELFTHYSAALLTERIVDEYAFDSDDMKKRINI
DLSQDFIFNLNDTLYSFILFNLLRNAVHYFSECNSTISIRLVKGFASNKVIFRDTGPGIDSHILPNIFDDFFTHNKEGGS
GLGLSYCLRVMHAFEGNIACYSKKGEFTEFVLSFPYIEGDLTSLINQQEHHESALPLIDVYDSGDTIKTILIVDDKKVQR
MLIQTFIAQDNMNILQAENGEEAISIAMNHPLDIIFMDSRMPVMNGIDAAKRIKLSYPNLPIIALTGESGHDEIQRISQV
MDGYLTKPISKPQLIQTLHKWV
>Mature_822_residues
MLIGFPKDKLLLFIAVFILLWVAFFIRSLFKERMKVDPKIYYPYIGYSIFIVFWVLINYYFQSNLLLHFSERVATTMAIL
ANLASYFAFAFAFLFSCRLSSTRKNKKMATWQIILFYAETIFAITINTIPNQTVTGVTIVEKGIFTIHFGPFASFFFINA
FLFIGLIFYNFFKLRKSTIRLNKEKSIYLLFGIVIFMISTIISQIIIPIIWQDFSFAWLPPALSVTEAILIGYTLLYHRL
YSLRYLAFWILSYSLNALIYLLPLFYIYKGASESNLLYMSIFLIVFTGLFWEKSLKRTKKMSSLLIYKDRKTPVEKIYAI
AEEFKFSSNNAMVKLAELLNTPKEDLLLVGKNANYNIFIPHLNKIHSALVKDELDYQIHYAPEKDNSSLHQVQEKMNESK
TALILPIFGENKHISHLLISSNKRDGSTFSNEEISAIQWVLTKVQGYIESERKVLQSQALANSIAHEMRNPLSQLQYHFE
RIKHHSSIDKENKELINNELRQGSLAIQRGAQLIDIILSEAKNTAINDELFTHYSAALLTERIVDEYAFDSDDMKKRINI
DLSQDFIFNLNDTLYSFILFNLLRNAVHYFSECNSTISIRLVKGFASNKVIFRDTGPGIDSHILPNIFDDFFTHNKEGGS
GLGLSYCLRVMHAFEGNIACYSKKGEFTEFVLSFPYIEGDLTSLINQQEHHESALPLIDVYDSGDTIKTILIVDDKKVQR
MLIQTFIAQDNMNILQAENGEEAISIAMNHPLDIIFMDSRMPVMNGIDAAKRIKLSYPNLPIIALTGESGHDEIQRISQV
MDGYLTKPISKPQLIQTLHKWV

Specific function: At low cell density, in the absence of AI-1 (autoinducer 1), luxN has a kinase activity and autophosphorylates on His-471. The phosphoryl group is then transferred on Asp-771 of the response regulator domain. The phosphoryl group is transferred to luxU, a

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=23.921568627451, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=370, Percent_Identity=22.972972972973, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=28.0632411067194, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 94655; Mature: 94655

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGFPKDKLLLFIAVFILLWVAFFIRSLFKERMKVDPKIYYPYIGYSIFIVFWVLINYY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHH
FQSNLLLHFSERVATTMAILANLASYFAFAFAFLFSCRLSSTRKNKKMATWQIILFYAET
HHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IFAITINTIPNQTVTGVTIVEKGIFTIHFGPFASFFFINAFLFIGLIFYNFFKLRKSTIR
HHEEEEECCCCCCCCCEEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LNKEKSIYLLFGIVIFMISTIISQIIIPIIWQDFSFAWLPPALSVTEAILIGYTLLYHRL
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHH
YSLRYLAFWILSYSLNALIYLLPLFYIYKGASESNLLYMSIFLIVFTGLFWEKSLKRTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MSSLLIYKDRKTPVEKIYAIAEEFKFSSNNAMVKLAELLNTPKEDLLLVGKNANYNIFIP
HHHHEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEEEECCCCEEEEEC
HLNKIHSALVKDELDYQIHYAPEKDNSSLHQVQEKMNESKTALILPIFGENKHISHLLIS
CHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEE
SNKRDGSTFSNEEISAIQWVLTKVQGYIESERKVLQSQALANSIAHEMRNPLSQLQYHFE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIKHHSSIDKENKELINNELRQGSLAIQRGAQLIDIILSEAKNTAINDELFTHYSAALLT
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ERIVDEYAFDSDDMKKRINIDLSQDFIFNLNDTLYSFILFNLLRNAVHYFSECNSTISIR
HHHHHHHCCCCHHHHHHCCCEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LVKGFASNKVIFRDTGPGIDSHILPNIFDDFFTHNKEGGSGLGLSYCLRVMHAFEGNIAC
EEECCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEE
YSKKGEFTEFVLSFPYIEGDLTSLINQQEHHESALPLIDVYDSGDTIKTILIVDDKKVQR
EECCCCHHHHHHHCCCCCHHHHHHHCHHHHHHCCCCEEEEECCCCCEEEEEEECCHHHHH
MLIQTFIAQDNMNILQAENGEEAISIAMNHPLDIIFMDSRMPVMNGIDAAKRIKLSYPNL
HHHHHHHHCCCCCEEECCCCCCEEEEEECCCEEEEEECCCCCHHCCCCHHHEEEEECCCC
PIIALTGESGHDEIQRISQVMDGYLTKPISKPQLIQTLHKWV
CEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLIGFPKDKLLLFIAVFILLWVAFFIRSLFKERMKVDPKIYYPYIGYSIFIVFWVLINYY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHH
FQSNLLLHFSERVATTMAILANLASYFAFAFAFLFSCRLSSTRKNKKMATWQIILFYAET
HHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IFAITINTIPNQTVTGVTIVEKGIFTIHFGPFASFFFINAFLFIGLIFYNFFKLRKSTIR
HHEEEEECCCCCCCCCEEEEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LNKEKSIYLLFGIVIFMISTIISQIIIPIIWQDFSFAWLPPALSVTEAILIGYTLLYHRL
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHH
YSLRYLAFWILSYSLNALIYLLPLFYIYKGASESNLLYMSIFLIVFTGLFWEKSLKRTKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MSSLLIYKDRKTPVEKIYAIAEEFKFSSNNAMVKLAELLNTPKEDLLLVGKNANYNIFIP
HHHHEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEEEECCCCEEEEEC
HLNKIHSALVKDELDYQIHYAPEKDNSSLHQVQEKMNESKTALILPIFGENKHISHLLIS
CHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEE
SNKRDGSTFSNEEISAIQWVLTKVQGYIESERKVLQSQALANSIAHEMRNPLSQLQYHFE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIKHHSSIDKENKELINNELRQGSLAIQRGAQLIDIILSEAKNTAINDELFTHYSAALLT
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ERIVDEYAFDSDDMKKRINIDLSQDFIFNLNDTLYSFILFNLLRNAVHYFSECNSTISIR
HHHHHHHCCCCHHHHHHCCCEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LVKGFASNKVIFRDTGPGIDSHILPNIFDDFFTHNKEGGSGLGLSYCLRVMHAFEGNIAC
EEECCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEE
YSKKGEFTEFVLSFPYIEGDLTSLINQQEHHESALPLIDVYDSGDTIKTILIVDDKKVQR
EECCCCHHHHHHHCCCCCHHHHHHHCHHHHHHCCCCEEEEECCCCCEEEEEEECCHHHHH
MLIQTFIAQDNMNILQAENGEEAISIAMNHPLDIIFMDSRMPVMNGIDAAKRIKLSYPNL
HHHHHHHHCCCCCEEECCCCCCEEEEEECCCEEEEEECCCCCHHCCCCHHHEEEEECCCC
PIIALTGESGHDEIQRISQVMDGYLTKPISKPQLIQTLHKWV
CEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8231809 [H]