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The map label for this gene is asd [H]

Identifier: 209694632

GI number: 209694632

Start: 1165585

End: 1166598

Strand: Direct

Name: asd [H]

Synonym: VSAL_I1073

Alternate gene names: 209694632

Gene position: 1165585-1166598 (Clockwise)

Preceding gene: 209694631

Following gene: 209694633

Centisome position: 35.05

GC content: 40.53

Gene sequence:

>1014_bases
ATGACTCAAGAATTTGATGTTGCCATTCTAGGCGCAACTGGTGCCGTTGGCGAAGCAATCATAAATGTATTACAAGAGCG
CAAGTTTCCTGTACGTAATTTATATCTTCTAGCTTCAGAGCGCAGTGAAGGCAAAACAGTTCGTTTTAATGGTAAAACAT
TAACGGTTGAAAACGTAGAAGAGTTTGATTGGAGTCAAGTGCAGTTAGGTCTATTTTCTGCTGGTAGCGAATTGTCTGCT
AAGTGGGCACCTATTGCGGCTGAATCTGGTGTTGTTGTTATCGATAACACATCACACTTCCGTTACGATCAGGACATCCC
ATTAGTGATTCCTGAAGTGAATCCAGAAGCATTAGCTGATTTCCGTAACCGTAACATTATTGCGAACCCTAATTGTTCAA
CGATTCAAATGTTAGTGGCATTAAAACCAATTCACGATGCTGTTGGTATTGATCGTATCAACGTATCTACGTATCAGTCA
GTATCTGGTTCAGGTAAAGCGGGTATTGATGAGCTTGCAGGCCAAACTGCAAAACTACTCAATGGACTGCCTGCAGAAAA
TAAAGCATACGATAAGCAAATTGCATTTAACTGTTTGCCTCATATTGATGAGTTTATGGATAATGGCTACACCAAAGAAG
AAATGAAAATGGTGTGGGAAACGCAAAAAATCTTTGCAGATGAGAGCATCACAGTAAATGCAACGTGTGTGCGTGTTCCT
GTTTTTTATGGCCATGCTGAATCTGTTCATGTTGAAACTCGTGCACCAATTGATGCAGAAGAAGCGACTCGCCTACTTGA
AGAAACCGATGGTATTGAAGTATTCCATGGTAATGATTACCCAACACAAGTAAGTGATGCAACTGGCAAAGATCATGTAA
TGGTTGCTCGTATTCGTGCTGACATTAGTCACCCTATGGGACTAAATATGTGGGTAGTTGCTGATAATGTACGTAAAGGT
GCGGCAACAAATGCGGTTCAAATTGCAGAAGTATTAATTCGTGACTATTACTAA

Upstream 100 bases:

>100_bases
ATTGGGATAGAAGAGAATACAGTGCAATCACTATCACGGGTAATAAAGACTGTGGTCTTACCCCGTTAAAACAACTTGGA
TTTACAATCGAGGAAGTCTA

Downstream 100 bases:

>100_bases
TCGTCGCTATTAATTTAATGATGAAAGAGTATCTTATTCATTGATTGGTAAGTTTATTTTTCTTTCTAAAAAAGCCTTAG
TGAAAACTAAGGCTTTTTTC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTQEFDVAILGATGAVGEAIINVLQERKFPVRNLYLLASERSEGKTVRFNGKTLTVENVEEFDWSQVQLGLFSAGSELSA
KWAPIAAESGVVVIDNTSHFRYDQDIPLVIPEVNPEALADFRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQS
VSGSGKAGIDELAGQTAKLLNGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADESITVNATCVRVP
VFYGHAESVHVETRAPIDAEEATRLLEETDGIEVFHGNDYPTQVSDATGKDHVMVARIRADISHPMGLNMWVVADNVRKG
AATNAVQIAEVLIRDYY

Sequences:

>Translated_337_residues
MTQEFDVAILGATGAVGEAIINVLQERKFPVRNLYLLASERSEGKTVRFNGKTLTVENVEEFDWSQVQLGLFSAGSELSA
KWAPIAAESGVVVIDNTSHFRYDQDIPLVIPEVNPEALADFRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQS
VSGSGKAGIDELAGQTAKLLNGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADESITVNATCVRVP
VFYGHAESVHVETRAPIDAEEATRLLEETDGIEVFHGNDYPTQVSDATGKDHVMVARIRADISHPMGLNMWVVADNVRKG
AATNAVQIAEVLIRDYY
>Mature_336_residues
TQEFDVAILGATGAVGEAIINVLQERKFPVRNLYLLASERSEGKTVRFNGKTLTVENVEEFDWSQVQLGLFSAGSELSAK
WAPIAAESGVVVIDNTSHFRYDQDIPLVIPEVNPEALADFRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQSV
SGSGKAGIDELAGQTAKLLNGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADESITVNATCVRVPV
FYGHAESVHVETRAPIDAEEATRLLEETDGIEVFHGNDYPTQVSDATGKDHVMVARIRADISHPMGLNMWVVADNVRKGA
ATNAVQIAEVLIRDYY

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=46.8842729970326, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=24.6498599439776, Blast_Score=81, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6320362, Length=385, Percent_Identity=29.6103896103896, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37140; Mature: 37009

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEFDVAILGATGAVGEAIINVLQERKFPVRNLYLLASERSEGKTVRFNGKTLTVENVE
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCEEEECCCC
EFDWSQVQLGLFSAGSELSAKWAPIAAESGVVVIDNTSHFRYDQDIPLVIPEVNPEALAD
CCCCCCEEEEEEECCCCCCCCCCCEECCCCEEEEECCCCEEECCCCCEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQSVSGSGKAGIDELAGQTAKLL
HHCCCEEECCCCHHEEEEEHHHHHHHHCCCCEEECHHHHCCCCCCCCCHHHHHHHHHHHH
NGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADESITVNATCVRVP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEE
VFYGHAESVHVETRAPIDAEEATRLLEETDGIEVFHGNDYPTQVSDATGKDHVMVARIRA
EEECCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEC
DISHPMGLNMWVVADNVRKGAATNAVQIAEVLIRDYY
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TQEFDVAILGATGAVGEAIINVLQERKFPVRNLYLLASERSEGKTVRFNGKTLTVENVE
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEECCCEEEECCCC
EFDWSQVQLGLFSAGSELSAKWAPIAAESGVVVIDNTSHFRYDQDIPLVIPEVNPEALAD
CCCCCCEEEEEEECCCCCCCCCCCEECCCCEEEEECCCCEEECCCCCEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIHDAVGIDRINVSTYQSVSGSGKAGIDELAGQTAKLL
HHCCCEEECCCCHHEEEEEHHHHHHHHCCCCEEECHHHHCCCCCCCCCHHHHHHHHHHHH
NGLPAENKAYDKQIAFNCLPHIDEFMDNGYTKEEMKMVWETQKIFADESITVNATCVRVP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEE
VFYGHAESVHVETRAPIDAEEATRLLEETDGIEVFHGNDYPTQVSDATGKDHVMVARIRA
EEECCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEC
DISHPMGLNMWVVADNVRKGAATNAVQIAEVLIRDYY
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]