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The map label for this gene is luxQ [H]

Identifier: 209694498

GI number: 209694498

Start: 1027355

End: 1029592

Strand: Direct

Name: luxQ [H]

Synonym: VSAL_I0930

Alternate gene names: 209694498

Gene position: 1027355-1029592 (Clockwise)

Preceding gene: 209694497

Following gene: 209694500

Centisome position: 30.9

GC content: 32.57

Gene sequence:

>2238_bases
ATGAATGATAAAAGAAAAGTACTGAAAAAAGCGTCGTTAGCCGATTTAATATTTCGTGCTATTTTTATTATATTTTCTAT
TTTGACCGTAGGCATTACTATTCATACTTATCAATTAAGCGTGAATACCATTAATGAAGAAGTTAAACGGAATTTAGAAC
AAACATCGGCACTATTAGAAAATTATTTTAATCATCGTTTAGCTATTTTACAAATTAGACAAGATACCGATGCGGGCAGC
CTCGGACTAACAGATCATTATGGTAATGGTCGAATTTTAAATTTAGAACAATATTTTTCAGATATAGAAGCTAAAGAACC
CTCAAACTCACCTGACTTTCGTTTTCTTGAAGCAAATAATCATGTTTTTTGGAGCGATGATAATCATTTGTTTCTTGGTA
TGAACTCTGAAAATTTAAAATATATTATAGATAAAAACATTTATATTAATACGTGGTATTACTTAACGGTTACTACAGAT
GAAAAAATAACGCATCTTTTGATTAGGCGAACACCTGTTGTTAGTTCTTTTACTGGAGAAGTTAGAAGTTATTTATACAA
TGCCGCAATATTAAATAATAATATTTCGTTTGTTCATAGTTTAAAGAGAGTGAGTCGTAGCCAAGAAATATTTATCGTTA
ATAATAAAAAATTAATATCGTCAACGATAAAGAAAAGTACCCCTAGATACGCAGAGGTCGAAAAGTGTATCGGAAATGGT
GTAGATACCTTTTCTGGAAAAATATTAAATTATACCCCGCTAAAAATAAAATCATTAAATGGTTCTTTATCGATCGTATC
GTTAAAAAATAAAGAGAATGTGACTTTACTTGAACAGCGTTTTATTTACAGTGTTGTTCTTTCCTTTTTTGTATTGATTG
CTATTGCGGTATTAGTCCGTGGCCTATTTGAACACCGAATTTTATTAGCATTAAACGCGCTTCTTTCTTATGCAAAAAGT
GTATCGAAAAAGAATGGGAATAAGCATTATCTTGGCAGTGGGATTCTTGAATTTGATCAAATAGGCGCAAAGCTTGAAGG
TATCTTTATTGAGCTTATTGAGGCAAAAGAAGAGAGTCATAAAGCACAAGCAGCCGCTGAAAAATTAACGCTAGTAAAAT
CTGATTTTCTTGCAAGAATGAGCCATGAAATCCGCACGCCACTGAATGGTATTCTAGGGATCTCTGGTTTATTAAAACAA
GCGCAACTTCCTTTAGAGCAGAAAAAACAAATTCAAATCATTCATCAAGGGGGAGAGCATTTATTAGCGGTATTAAACGA
TATTTTAGATTTCTCTCAGATAGAGCAAGATAAGTTAAATATTAATTTTGAAGAGTTTGTTCTTGATGATGTACTCGATA
CGATTAATGCGATATATACGCCACTTTGTATGGAAAAAAATATTACGTTCAATCTAAATAATAACATTGATAATAATGTT
ATTTTATATACAGATAAAGTTCGATTAACTCAAATCCTATTTAATTTATTGAGTAATGGCGTGAAGTTTACTGAGATTGG
ACAGGTCACCCTTAGCTTAAATCTTGAATCAAAAAATGGACAAATATTTTTATGTTTTGATGTTGAGGATACCGGGGTTG
GTATTGATATTGAAAACCAAGCATCGGTGTTTGACCCATTTATACAAGTGGAATCGACTGGAACAAGAAAATTTGGTGGC
AGTGGTCTCGGTTTGGCGATCGTTAAGCAATTATTGCATTTGCTTAATGGGTCGATTACGGTTGTTAGCTCACCGGGTTT
AGGGACGTCATTTACGATTAGGCTTCCTGTTGAAGTGATCGAGTATAAAAAAGAACTGCCTTTAGCCGCTTCAAGTCATA
ATGAATATTTATTGCCAACAAATTTGAAAGTATTATTGGTAGAAGATAATAAATCTAATGCGTATATCGCAAAAGCATAC
TGTCAAAAATACAGCTTAGATGTAACGTGGGTAACTTCTGCGGCTGAAGGGATTCAAATGATTAAAGAACACTCATTTGA
TTTGGTTTTGATGGATAATCAAATGCCAGAAATGAGTGGGATAGAAGCCACAAGATACATAAGAAAAATACTTAATTTGA
GTCTGCCAATTTATGCTTATACTGCAGATGTTTTAGAAGACGCGACAAACGAATTCTTATCTGCAGGTGCGGATTACATT
ATAACTAAGCCAATTAAAGAAAAATCGATTTTAGATGCTTTGGTTTTTTATAAAGCAGAGCTAAAACGGAAAAATTAA

Upstream 100 bases:

>100_bases
TTTTCTGGCGATTTTGAAATGGTAACATCAGAAACGACAGAAGAAGAGTTACGTCAATTTAAAGAATGCGCATTCCGTTA
CTCAGGAATTGATTGATCGC

Downstream 100 bases:

>100_bases
CTGCGTTTAATTCGAACAACTTTCATTATTTCAAGTTCAAAACCGGCAAGAGACTCAGTACTAGGATAGTAAGTCATGTT
TACGTTCGCGCCTTTAAGTG

Product: autoinducer 2 sensor kinase/phosphatase LuxQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 745; Mature: 745

Protein sequence:

>745_residues
MNDKRKVLKKASLADLIFRAIFIIFSILTVGITIHTYQLSVNTINEEVKRNLEQTSALLENYFNHRLAILQIRQDTDAGS
LGLTDHYGNGRILNLEQYFSDIEAKEPSNSPDFRFLEANNHVFWSDDNHLFLGMNSENLKYIIDKNIYINTWYYLTVTTD
EKITHLLIRRTPVVSSFTGEVRSYLYNAAILNNNISFVHSLKRVSRSQEIFIVNNKKLISSTIKKSTPRYAEVEKCIGNG
VDTFSGKILNYTPLKIKSLNGSLSIVSLKNKENVTLLEQRFIYSVVLSFFVLIAIAVLVRGLFEHRILLALNALLSYAKS
VSKKNGNKHYLGSGILEFDQIGAKLEGIFIELIEAKEESHKAQAAAEKLTLVKSDFLARMSHEIRTPLNGILGISGLLKQ
AQLPLEQKKQIQIIHQGGEHLLAVLNDILDFSQIEQDKLNINFEEFVLDDVLDTINAIYTPLCMEKNITFNLNNNIDNNV
ILYTDKVRLTQILFNLLSNGVKFTEIGQVTLSLNLESKNGQIFLCFDVEDTGVGIDIENQASVFDPFIQVESTGTRKFGG
SGLGLAIVKQLLHLLNGSITVVSSPGLGTSFTIRLPVEVIEYKKELPLAASSHNEYLLPTNLKVLLVEDNKSNAYIAKAY
CQKYSLDVTWVTSAAEGIQMIKEHSFDLVLMDNQMPEMSGIEATRYIRKILNLSLPIYAYTADVLEDATNEFLSAGADYI
ITKPIKEKSILDALVFYKAELKRKN

Sequences:

>Translated_745_residues
MNDKRKVLKKASLADLIFRAIFIIFSILTVGITIHTYQLSVNTINEEVKRNLEQTSALLENYFNHRLAILQIRQDTDAGS
LGLTDHYGNGRILNLEQYFSDIEAKEPSNSPDFRFLEANNHVFWSDDNHLFLGMNSENLKYIIDKNIYINTWYYLTVTTD
EKITHLLIRRTPVVSSFTGEVRSYLYNAAILNNNISFVHSLKRVSRSQEIFIVNNKKLISSTIKKSTPRYAEVEKCIGNG
VDTFSGKILNYTPLKIKSLNGSLSIVSLKNKENVTLLEQRFIYSVVLSFFVLIAIAVLVRGLFEHRILLALNALLSYAKS
VSKKNGNKHYLGSGILEFDQIGAKLEGIFIELIEAKEESHKAQAAAEKLTLVKSDFLARMSHEIRTPLNGILGISGLLKQ
AQLPLEQKKQIQIIHQGGEHLLAVLNDILDFSQIEQDKLNINFEEFVLDDVLDTINAIYTPLCMEKNITFNLNNNIDNNV
ILYTDKVRLTQILFNLLSNGVKFTEIGQVTLSLNLESKNGQIFLCFDVEDTGVGIDIENQASVFDPFIQVESTGTRKFGG
SGLGLAIVKQLLHLLNGSITVVSSPGLGTSFTIRLPVEVIEYKKELPLAASSHNEYLLPTNLKVLLVEDNKSNAYIAKAY
CQKYSLDVTWVTSAAEGIQMIKEHSFDLVLMDNQMPEMSGIEATRYIRKILNLSLPIYAYTADVLEDATNEFLSAGADYI
ITKPIKEKSILDALVFYKAELKRKN
>Mature_745_residues
MNDKRKVLKKASLADLIFRAIFIIFSILTVGITIHTYQLSVNTINEEVKRNLEQTSALLENYFNHRLAILQIRQDTDAGS
LGLTDHYGNGRILNLEQYFSDIEAKEPSNSPDFRFLEANNHVFWSDDNHLFLGMNSENLKYIIDKNIYINTWYYLTVTTD
EKITHLLIRRTPVVSSFTGEVRSYLYNAAILNNNISFVHSLKRVSRSQEIFIVNNKKLISSTIKKSTPRYAEVEKCIGNG
VDTFSGKILNYTPLKIKSLNGSLSIVSLKNKENVTLLEQRFIYSVVLSFFVLIAIAVLVRGLFEHRILLALNALLSYAKS
VSKKNGNKHYLGSGILEFDQIGAKLEGIFIELIEAKEESHKAQAAAEKLTLVKSDFLARMSHEIRTPLNGILGISGLLKQ
AQLPLEQKKQIQIIHQGGEHLLAVLNDILDFSQIEQDKLNINFEEFVLDDVLDTINAIYTPLCMEKNITFNLNNNIDNNV
ILYTDKVRLTQILFNLLSNGVKFTEIGQVTLSLNLESKNGQIFLCFDVEDTGVGIDIENQASVFDPFIQVESTGTRKFGG
SGLGLAIVKQLLHLLNGSITVVSSPGLGTSFTIRLPVEVIEYKKELPLAASSHNEYLLPTNLKVLLVEDNKSNAYIAKAY
CQKYSLDVTWVTSAAEGIQMIKEHSFDLVLMDNQMPEMSGIEATRYIRKILNLSLPIYAYTADVLEDATNEFLSAGADYI
ITKPIKEKSILDALVFYKAELKRKN

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=430, Percent_Identity=33.7209302325581, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI87081816, Length=402, Percent_Identity=31.8407960199005, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=40, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1788713, Length=386, Percent_Identity=30.5699481865285, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1789149, Length=250, Percent_Identity=35.2, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788549, Length=262, Percent_Identity=27.0992366412214, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=25, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=26.2096774193548, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=27.4261603375527, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=27.1966527196653, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790346, Length=298, Percent_Identity=26.510067114094, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=27.7056277056277, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=26.9058295964126, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=28.125, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790861, Length=222, Percent_Identity=27.027027027027, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=45.945945945946, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83891; Mature: 83891

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKRKVLKKASLADLIFRAIFIIFSILTVGITIHTYQLSVNTINEEVKRNLEQTSALLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEHHHHHHHHHHHHHHHHHHH
NYFNHRLAILQIRQDTDAGSLGLTDHYGNGRILNLEQYFSDIEAKEPSNSPDFRFLEANN
HHHCCEEEEEEEECCCCCCCCCCEEECCCCEEEEHHHHHHHCCCCCCCCCCCEEEEECCC
HVFWSDDNHLFLGMNSENLKYIIDKNIYINTWYYLTVTTDEKITHLLIRRTPVVSSFTGE
EEEECCCCEEEEEECCCCCEEEEECCEEEEEEEEEEEECCHHHHHHHHHCCCCHHHHHHH
VRSYLYNAAILNNNISFVHSLKRVSRSQEIFIVNNKKLISSTIKKSTPRYAEVEKCIGNG
HHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHCCC
VDTFSGKILNYTPLKIKSLNGSLSIVSLKNKENVTLLEQRFIYSVVLSFFVLIAIAVLVR
CCCCCCCEEEECCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFEHRILLALNALLSYAKSVSKKNGNKHYLGSGILEFDQIGAKLEGIFIELIEAKEESH
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
KAQAAAEKLTLVKSDFLARMSHEIRTPLNGILGISGLLKQAQLPLEQKKQIQIIHQGGEH
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHH
LLAVLNDILDFSQIEQDKLNINFEEFVLDDVLDTINAIYTPLCMEKNITFNLNNNIDNNV
HHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCCE
ILYTDKVRLTQILFNLLSNGVKFTEIGQVTLSLNLESKNGQIFLCFDVEDTGVGIDIENQ
EEEECCHHHHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCEEEEEEEECCCCCEEEECCC
ASVFDPFIQVESTGTRKFGGSGLGLAIVKQLLHLLNGSITVVSSPGLGTSFTIRLPVEVI
CHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECHHHH
EYKKELPLAASSHNEYLLPTNLKVLLVEDNKSNAYIAKAYCQKYSLDVTWVTSAAEGIQM
HHHHHCCCEECCCCCEEECCCCEEEEEECCCCCEEEEEEHHHHHCCEEEEECCHHHHHHH
IKEHSFDLVLMDNQMPEMSGIEATRYIRKILNLSLPIYAYTADVLEDATNEFLSAGADYI
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
ITKPIKEKSILDALVFYKAELKRKN
EECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDKRKVLKKASLADLIFRAIFIIFSILTVGITIHTYQLSVNTINEEVKRNLEQTSALLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEHHHHHHHHHHHHHHHHHHH
NYFNHRLAILQIRQDTDAGSLGLTDHYGNGRILNLEQYFSDIEAKEPSNSPDFRFLEANN
HHHCCEEEEEEEECCCCCCCCCCEEECCCCEEEEHHHHHHHCCCCCCCCCCCEEEEECCC
HVFWSDDNHLFLGMNSENLKYIIDKNIYINTWYYLTVTTDEKITHLLIRRTPVVSSFTGE
EEEECCCCEEEEEECCCCCEEEEECCEEEEEEEEEEEECCHHHHHHHHHCCCCHHHHHHH
VRSYLYNAAILNNNISFVHSLKRVSRSQEIFIVNNKKLISSTIKKSTPRYAEVEKCIGNG
HHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHCCC
VDTFSGKILNYTPLKIKSLNGSLSIVSLKNKENVTLLEQRFIYSVVLSFFVLIAIAVLVR
CCCCCCCEEEECCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLFEHRILLALNALLSYAKSVSKKNGNKHYLGSGILEFDQIGAKLEGIFIELIEAKEESH
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHH
KAQAAAEKLTLVKSDFLARMSHEIRTPLNGILGISGLLKQAQLPLEQKKQIQIIHQGGEH
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHH
LLAVLNDILDFSQIEQDKLNINFEEFVLDDVLDTINAIYTPLCMEKNITFNLNNNIDNNV
HHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCCE
ILYTDKVRLTQILFNLLSNGVKFTEIGQVTLSLNLESKNGQIFLCFDVEDTGVGIDIENQ
EEEECCHHHHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCEEEEEEEECCCCCEEEECCC
ASVFDPFIQVESTGTRKFGGSGLGLAIVKQLLHLLNGSITVVSSPGLGTSFTIRLPVEVI
CHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECHHHH
EYKKELPLAASSHNEYLLPTNLKVLLVEDNKSNAYIAKAYCQKYSLDVTWVTSAAEGIQM
HHHHHCCCEECCCCCEEECCCCEEEEEECCCCCEEEEEEHHHHHCCEEEEECCHHHHHHH
IKEHSFDLVLMDNQMPEMSGIEATRYIRKILNLSLPIYAYTADVLEDATNEFLSAGADYI
HHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
ITKPIKEKSILDALVFYKAELKRKN
EECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA